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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of McQFold - scored higher in this pairwise comparison

  4. Performance of PETfold_2.0(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for McQFold & PETfold_2.0(seed) [.zip] - may take several seconds...


Overview

Metric McQFold PETfold_2.0(seed)
MCC 0.860 > 0.831
Average MCC ± 95% Confidence Intervals 0.860 ± > 0.831 ±
Sensitivity 0.774 < 0.806
Positive Predictive Value 0.960 > 0.862
Total TP 24 < 25
Total TN 1653 > 1649
Total FP 1 < 5
Total FP CONTRA 1 < 2
Total FP INCONS 0 < 2
Total FP COMP 0 < 1
Total FN 7 > 6
P-value 0.0

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Performance plots


  1. Comparison of performance of McQFold and PETfold_2.0(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for McQFold and PETfold_2.0(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for McQFold and PETfold_2.0(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for McQFold and PETfold_2.0(seed)).

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Performance of McQFold - scored higher in this pairwise comparison

1. Total counts & total scores for McQFold

Total Base Pair Counts
Total TP 24
Total TN 1653
Total FP 1
Total FP CONTRA 1
Total FP INCONS 0
Total FP COMP 0
Total FN 7
Total Scores
MCC 0.860
Average MCC ± 95% Confidence Intervals 0.860 ±
Sensitivity 0.774
Positive Predictive Value 0.960
Nr of predictions 1

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2. Individual counts for McQFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3W1K_J 0.86 0.77 0.96 24 1653 1 1 0 0 7

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Performance of PETfold_2.0(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for PETfold_2.0(seed)

Total Base Pair Counts
Total TP 25
Total TN 1649
Total FP 5
Total FP CONTRA 2
Total FP INCONS 2
Total FP COMP 1
Total FN 6
Total Scores
MCC 0.831
Average MCC ± 95% Confidence Intervals 0.831 ±
Sensitivity 0.806
Positive Predictive Value 0.862
Nr of predictions 1

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2. Individual counts for PETfold_2.0(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3W1K_J 0.83 0.81 0.86 25 1649 5 2 2 1 6

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.