CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Multilign(seed) - scored higher in this pairwise comparison

  4. Performance of Mastr(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for Multilign(seed) & Mastr(20) [.zip] - may take several seconds...


Overview

Metric Multilign(seed) Mastr(20)
MCC 0.625 > 0.531
Average MCC ± 95% Confidence Intervals 0.598 ± 0.338 > 0.397 ± 0.490
Sensitivity 0.587 > 0.381
Positive Predictive Value 0.673 < 0.750
Total TP 74 > 48
Total TN 11842 < 11888
Total FP 38 > 17
Total FP CONTRA 16 > 5
Total FP INCONS 20 > 11
Total FP COMP 2 > 1
Total FN 52 < 78
P-value 0.0

^top




Performance plots


  1. Comparison of performance of Multilign(seed) and Mastr(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(seed) and Mastr(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(seed) and Mastr(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(seed) and Mastr(20)).

^top





Performance of Multilign(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 74
Total TN 11842
Total FP 38
Total FP CONTRA 16
Total FP INCONS 20
Total FP COMP 2
Total FN 52
Total Scores
MCC 0.625
Average MCC ± 95% Confidence Intervals 0.598 ± 0.338
Sensitivity 0.587
Positive Predictive Value 0.673
Nr of predictions 5

^top



2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3E_8 0.19 0.20 0.19 3 2726 13 8 5 0 12
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.66 0.66 0.68 19 1505 9 4 5 0 10
3ZEX_C 0.50 0.45 0.57 13 5351 11 3 7 1 16
4AOB_A 0.73 0.66 0.83 19 1414 5 1 3 1 10

^top



Performance of Mastr(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(20)

Total Base Pair Counts
Total TP 48
Total TN 11888
Total FP 17
Total FP CONTRA 5
Total FP INCONS 11
Total FP COMP 1
Total FN 78
Total Scores
MCC 0.531
Average MCC ± 95% Confidence Intervals 0.397 ± 0.490
Sensitivity 0.381
Positive Predictive Value 0.750
Nr of predictions 5

^top



2. Individual counts for Mastr(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3E_8 0.00 0.00 0.00 0 2742 0 0 0 0 15
3RKF_A 0.84 0.71 1.00 17 849 0 0 0 0 7
3SD1_A 0.73 0.72 0.75 21 1505 7 4 3 0 8
3ZEX_C 0.00 0.00 0.00 0 5374 0 0 0 0 29
4AOB_A 0.42 0.34 0.53 10 1418 10 1 8 1 19

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.