CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Multilign(seed) - scored higher in this pairwise comparison

  4. Performance of NanoFolder - scored lower in this pairwise comparison

  5. Compile and download dataset for Multilign(seed) & NanoFolder [.zip] - may take several seconds...


Overview

Metric Multilign(seed) NanoFolder
MCC 0.637 > 0.319
Average MCC ± 95% Confidence Intervals 0.540 ± 0.537 > 0.328 ± 0.298
Sensitivity 0.588 > 0.387
Positive Predictive Value 0.700 > 0.284
Total TP 70 > 46
Total TN 7678 > 7616
Total FP 32 < 131
Total FP CONTRA 11 < 27
Total FP INCONS 19 < 89
Total FP COMP 2 < 15
Total FN 49 < 73
P-value 0.0

^top




Performance plots


  1. Comparison of performance of Multilign(seed) and NanoFolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(seed) and NanoFolder).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(seed) and NanoFolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(seed) and NanoFolder).

^top





Performance of Multilign(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 70
Total TN 7678
Total FP 32
Total FP CONTRA 11
Total FP INCONS 19
Total FP COMP 2
Total FN 49
Total Scores
MCC 0.637
Average MCC ± 95% Confidence Intervals 0.540 ± 0.537
Sensitivity 0.588
Positive Predictive Value 0.700
Nr of predictions 5

^top



2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 516 12 2 10 0 18
3J3E_8 0.19 0.20 0.19 3 2726 13 8 5 0 12
3W3S_B 0.92 0.88 0.97 29 1959 2 0 1 1 4
4AOB_A 0.73 0.66 0.83 19 1414 5 1 3 1 10
4JF2_A 0.89 0.79 1.00 19 1063 0 0 0 0 5

^top



Performance of NanoFolder - scored lower in this pairwise comparison

1. Total counts & total scores for NanoFolder

Total Base Pair Counts
Total TP 46
Total TN 7616
Total FP 131
Total FP CONTRA 27
Total FP INCONS 89
Total FP COMP 15
Total FN 73
Total Scores
MCC 0.319
Average MCC ± 95% Confidence Intervals 0.328 ± 0.298
Sensitivity 0.387
Positive Predictive Value 0.284
Nr of predictions 5

^top



2. Individual counts for NanoFolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.54 0.61 0.50 11 506 11 1 10 0 7
3J3E_8 -0.01 0.00 0.00 0 2707 47 11 24 12 15
3W3S_B 0.18 0.21 0.18 7 1949 34 2 31 1 26
4AOB_A 0.39 0.41 0.39 12 1406 20 4 15 1 17
4JF2_A 0.55 0.67 0.47 16 1048 19 9 9 1 8

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.