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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Murlet(seed) - scored higher in this pairwise comparison

  4. Performance of Mastr(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for Murlet(seed) & Mastr(20) [.zip] - may take several seconds...


Overview

Metric Murlet(seed) Mastr(20)
MCC 0.564 > 0.457
Average MCC ± 95% Confidence Intervals 0.561 ± 0.072 > 0.347 ± 0.188
Sensitivity 0.366 > 0.290
Positive Predictive Value 0.876 > 0.731
Total TP 148 > 117
Total TN 38418 < 38427
Total FP 28 < 47
Total FP CONTRA 4 < 10
Total FP INCONS 17 < 33
Total FP COMP 7 > 4
Total FN 256 < 287
P-value 1.91441904741e-08

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Performance plots


  1. Comparison of performance of Murlet(seed) and Mastr(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Murlet(seed) and Mastr(20)).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for Murlet(seed) and Mastr(20)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for Murlet(seed) and Mastr(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Murlet(seed) and Mastr(20)).

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Performance of Murlet(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Murlet(seed)

Total Base Pair Counts
Total TP 148
Total TN 38418
Total FP 28
Total FP CONTRA 4
Total FP INCONS 17
Total FP COMP 7
Total FN 256
Total Scores
MCC 0.564
Average MCC ± 95% Confidence Intervals 0.561 ± 0.072
Sensitivity 0.366
Positive Predictive Value 0.876
Nr of predictions 16

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2. Individual counts for Murlet(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3GX2_A 0.70 0.50 1.00 14 1435 1 0 0 1 14
3IVN_B 0.62 0.52 0.75 12 887 4 2 2 0 11
3J3E_8 0.36 0.13 1.00 2 2740 2 0 0 2 13
3J3F_8 0.61 0.37 1.00 7 4754 0 0 0 0 12
3LA5_A 0.67 0.56 0.82 14 937 3 1 2 0 11
3NPB_A 0.59 0.35 1.00 13 2265 2 0 0 2 24
3O58_3 0.52 0.27 1.00 6 4758 1 0 0 1 16
3PDR_A 0.53 0.28 1.00 14 4826 0 0 0 0 36
3RKF_A 0.62 0.50 0.80 12 851 3 1 2 0 12
3SD1_A 0.56 0.38 0.85 11 1520 2 0 2 0 18
3ZEX_C 0.49 0.24 1.00 7 5367 0 0 0 0 22
4A1C_2 0.59 0.35 1.00 7 4509 0 0 0 0 13
4AOB_A 0.69 0.48 1.00 14 1423 1 0 0 1 15
4ENB_A 0.63 0.40 1.00 6 466 0 0 0 0 9
4ENC_A 0.63 0.40 1.00 6 490 0 0 0 0 9
4FRG_B 0.17 0.13 0.25 3 1190 9 0 9 0 21

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Performance of Mastr(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(20)

Total Base Pair Counts
Total TP 117
Total TN 38427
Total FP 47
Total FP CONTRA 10
Total FP INCONS 33
Total FP COMP 4
Total FN 287
Total Scores
MCC 0.457
Average MCC ± 95% Confidence Intervals 0.347 ± 0.188
Sensitivity 0.290
Positive Predictive Value 0.731
Nr of predictions 16

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2. Individual counts for Mastr(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3GX2_A 0.46 0.39 0.55 11 1429 10 2 7 1 17
3IVN_B 0.86 0.83 0.90 19 882 2 2 0 0 4
3J3E_8 0.00 0.00 0.00 0 2742 0 0 0 0 15
3J3F_8 0.00 0.00 0.00 0 4761 0 0 0 0 19
3LA5_A 0.89 0.80 1.00 20 934 0 0 0 0 5
3NPB_A 0.34 0.30 0.41 11 2251 18 1 15 2 26
3O58_3 0.00 0.00 0.00 0 4764 0 0 0 0 22
3PDR_A 0.00 0.00 0.00 0 4840 0 0 0 0 50
3RKF_A 0.84 0.71 1.00 17 849 0 0 0 0 7
3SD1_A 0.73 0.72 0.75 21 1505 7 4 3 0 8
3ZEX_C 0.00 0.00 0.00 0 5374 0 0 0 0 29
4A1C_2 0.00 0.00 0.00 0 4516 0 0 0 0 20
4AOB_A 0.42 0.34 0.53 10 1418 10 1 8 1 19
4ENB_A 0.44 0.20 1.00 3 469 0 0 0 0 12
4ENC_A 0.57 0.33 1.00 5 491 0 0 0 0 10
4FRG_B 0.00 0.00 0.00 0 1202 0 0 0 0 24

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.