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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Murlet(seed) - scored higher in this pairwise comparison

  4. Performance of Mastr(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Murlet(seed) & Mastr(seed) [.zip] - may take several seconds...


Overview

Metric Murlet(seed) Mastr(seed)
MCC 0.534 > 0.043
Average MCC ± 95% Confidence Intervals 0.529 ± 0.077 > 0.009 ± 0.020
Sensitivity 0.349 > 0.005
Positive Predictive Value 0.828 > 0.375
Total TP 198 > 3
Total TN 46973 < 47204
Total FP 50 > 5
Total FP CONTRA 6 > 0
Total FP INCONS 35 > 5
Total FP COMP 9 > 0
Total FN 370 < 565
P-value 5.02343278931e-08

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Performance plots


  1. Comparison of performance of Murlet(seed) and Mastr(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Murlet(seed) and Mastr(seed)).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for Murlet(seed) and Mastr(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for Murlet(seed) and Mastr(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Murlet(seed) and Mastr(seed)).

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Performance of Murlet(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Murlet(seed)

Total Base Pair Counts
Total TP 198
Total TN 46973
Total FP 50
Total FP CONTRA 6
Total FP INCONS 35
Total FP COMP 9
Total FN 370
Total Scores
MCC 0.534
Average MCC ± 95% Confidence Intervals 0.529 ± 0.077
Sensitivity 0.349
Positive Predictive Value 0.828
Nr of predictions 22

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2. Individual counts for Murlet(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 516 12 0 12 0 18
3A3A_A 0.63 0.40 1.00 12 1488 0 0 0 0 18
3GX2_A 0.70 0.50 1.00 14 1435 1 0 0 1 14
3IVN_B 0.62 0.52 0.75 12 887 4 2 2 0 11
3J3E_8 0.36 0.13 1.00 2 2740 2 0 0 2 13
3J3F_8 0.61 0.37 1.00 7 4754 0 0 0 0 12
3LA5_A 0.67 0.56 0.82 14 937 3 1 2 0 11
3NPB_A 0.59 0.35 1.00 13 2265 2 0 0 2 24
3O58_3 0.52 0.27 1.00 6 4758 1 0 0 1 16
3PDR_A 0.53 0.28 1.00 14 4826 0 0 0 0 36
3RKF_A 0.62 0.50 0.80 12 851 3 1 2 0 12
3SD1_A 0.56 0.38 0.85 11 1520 2 0 2 0 18
3W1K_J 0.47 0.26 0.89 8 1669 1 0 1 0 23
3W3S_B 0.45 0.27 0.75 9 1977 3 0 3 0 24
3ZEX_C 0.49 0.24 1.00 7 5367 0 0 0 0 22
4A1C_2 0.59 0.35 1.00 7 4509 0 0 0 0 13
4AOB_A 0.69 0.48 1.00 14 1423 1 0 0 1 15
4ENB_A 0.63 0.40 1.00 6 466 0 0 0 0 9
4ENC_A 0.63 0.40 1.00 6 490 0 0 0 0 9
4FRG_B 0.17 0.13 0.25 3 1190 9 0 9 0 21
4FRN_A 0.66 0.50 0.88 14 1832 2 1 1 0 14
4JF2_A 0.47 0.29 0.78 7 1073 4 1 1 2 17

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Performance of Mastr(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(seed)

Total Base Pair Counts
Total TP 3
Total TN 47204
Total FP 5
Total FP CONTRA 0
Total FP INCONS 5
Total FP COMP 0
Total FN 565
Total Scores
MCC 0.043
Average MCC ± 95% Confidence Intervals 0.009 ± 0.020
Sensitivity 0.005
Positive Predictive Value 0.375
Nr of predictions 22

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2. Individual counts for Mastr(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.00 0.00 0.00 0 528 0 0 0 0 18
3A3A_A 0.00 0.00 0.00 0 1500 0 0 0 0 30
3GX2_A 0.00 0.00 0.00 0 1449 0 0 0 0 28
3IVN_B 0.00 0.00 0.00 0 903 0 0 0 0 23
3J3E_8 0.00 0.00 0.00 0 2742 0 0 0 0 15
3J3F_8 0.00 0.00 0.00 0 4761 0 0 0 0 19
3LA5_A 0.00 0.00 0.00 0 954 0 0 0 0 25
3NPB_A 0.00 0.00 0.00 0 2278 0 0 0 0 37
3O58_3 0.00 0.00 0.00 0 4764 0 0 0 0 22
3PDR_A 0.00 0.00 0.00 0 4840 0 0 0 0 50
3RKF_A 0.00 0.00 0.00 0 866 0 0 0 0 24
3SD1_A 0.00 0.00 0.00 0 1533 0 0 0 0 29
3W1K_J 0.00 0.00 0.00 0 1678 0 0 0 0 31
3W3S_B 0.00 0.00 0.00 0 1989 0 0 0 0 33
3ZEX_C 0.00 0.00 0.00 0 5374 0 0 0 0 29
4A1C_2 0.00 0.00 0.00 0 4516 0 0 0 0 20
4AOB_A 0.00 0.00 0.00 0 1437 0 0 0 0 29
4ENB_A 0.00 0.00 0.00 0 472 0 0 0 0 15
4ENC_A 0.00 0.00 0.00 0 496 0 0 0 0 15
4FRG_B 0.00 0.00 0.00 0 1202 0 0 0 0 24
4FRN_A 0.00 0.00 0.00 0 1848 0 0 0 0 28
4JF2_A 0.21 0.13 0.38 3 1074 5 0 5 0 21

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.