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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of Afold - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & Afold [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) Afold
MCC 0.428 > 0.353
Average MCC ± 95% Confidence Intervals 0.469 ± 0.540 > 0.421 ± 0.851
Sensitivity 0.400 < 0.420
Positive Predictive Value 0.465 > 0.304
Total TP 20 < 21
Total TN 7687 > 7661
Total FP 37 < 77
Total FP CONTRA 4 < 17
Total FP INCONS 19 < 31
Total FP COMP 14 < 29
Total FN 30 > 29
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and Afold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and Afold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and Afold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and Afold).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 20
Total TN 7687
Total FP 37
Total FP CONTRA 4
Total FP INCONS 19
Total FP COMP 14
Total FN 30
Total Scores
MCC 0.428
Average MCC ± 95% Confidence Intervals 0.469 ± 0.540
Sensitivity 0.400
Positive Predictive Value 0.465
Nr of predictions 3

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3E_8 0.48 0.47 0.50 7 2728 11 2 5 4 8
4A1C_2 0.25 0.25 0.25 5 4496 25 2 13 10 15
4ENB_A 0.68 0.53 0.89 8 463 1 0 1 0 7

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Performance of Afold - scored lower in this pairwise comparison

1. Total counts & total scores for Afold

Total Base Pair Counts
Total TP 21
Total TN 7661
Total FP 77
Total FP CONTRA 17
Total FP INCONS 31
Total FP COMP 29
Total FN 29
Total Scores
MCC 0.353
Average MCC ± 95% Confidence Intervals 0.421 ± 0.851
Sensitivity 0.420
Positive Predictive Value 0.304
Nr of predictions 3

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2. Individual counts for Afold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3E_8 0.26 0.33 0.21 5 2718 31 6 13 12 10
4A1C_2 0.19 0.25 0.15 5 4483 43 11 17 15 15
4ENB_A 0.81 0.73 0.92 11 460 3 0 1 2 4

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.