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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of CMfinder(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & CMfinder(20) [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) CMfinder(20)
MCC 0.722 > 0.580
Average MCC ± 95% Confidence Intervals 0.706 ± 0.343 > 0.564 ± 0.352
Sensitivity 0.724 > 0.500
Positive Predictive Value 0.724 > 0.681
Total TP 71 > 49
Total TN 10794 < 10820
Total FP 41 > 26
Total FP CONTRA 11 < 12
Total FP INCONS 16 > 11
Total FP COMP 14 > 3
Total FN 27 < 49
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and CMfinder(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and CMfinder(20)).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 71
Total TN 10794
Total FP 41
Total FP CONTRA 11
Total FP INCONS 16
Total FP COMP 14
Total FN 27
Total Scores
MCC 0.722
Average MCC ± 95% Confidence Intervals 0.706 ± 0.343
Sensitivity 0.724
Positive Predictive Value 0.724
Nr of predictions 5

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.95 0.95 0.95 20 1198 1 1 0 0 1
3J3D_C 0.87 0.89 0.85 17 948 3 3 0 0 2
3J3E_8 0.48 0.47 0.50 7 2728 11 2 5 4 8
3J3F_8 0.34 0.37 0.32 7 4739 24 5 10 9 12
4FRG_B 0.89 0.83 0.95 20 1181 2 0 1 1 4

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Performance of CMfinder(20) - scored lower in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 49
Total TN 10820
Total FP 26
Total FP CONTRA 12
Total FP INCONS 11
Total FP COMP 3
Total FN 49
Total Scores
MCC 0.580
Average MCC ± 95% Confidence Intervals 0.564 ± 0.352
Sensitivity 0.500
Positive Predictive Value 0.681
Nr of predictions 5

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.84 0.76 0.94 16 1202 2 1 0 1 5
3J3D_C 0.81 0.79 0.83 15 950 3 3 0 0 4
3J3E_8 0.14 0.13 0.17 2 2730 10 3 7 0 13
3J3F_8 0.48 0.47 0.50 9 4743 11 5 4 2 10
4FRG_B 0.54 0.29 1.00 7 1195 0 0 0 0 17

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.