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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of Multilign(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & Multilign(seed) [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) Multilign(seed)
MCC 0.553 > 0.517
Average MCC ± 95% Confidence Intervals 0.538 ± 0.768 > 0.474 ± 0.676
Sensitivity 0.521 > 0.479
Positive Predictive Value 0.594 > 0.565
Total TP 38 > 35
Total TN 9489 < 9491
Total FP 35 > 29
Total FP CONTRA 3 < 12
Total FP INCONS 23 > 15
Total FP COMP 9 > 2
Total FN 35 < 38
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and Multilign(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and Multilign(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and Multilign(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and Multilign(seed)).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 38
Total TN 9489
Total FP 35
Total FP CONTRA 3
Total FP INCONS 23
Total FP COMP 9
Total FN 35
Total Scores
MCC 0.553
Average MCC ± 95% Confidence Intervals 0.538 ± 0.768
Sensitivity 0.521
Positive Predictive Value 0.594
Nr of predictions 3

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3E_8 0.48 0.47 0.50 7 2728 11 2 5 4 8
3ZEX_C 0.26 0.24 0.29 7 5350 20 1 16 3 22
4AOB_A 0.87 0.83 0.92 24 1411 4 0 2 2 5

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Performance of Multilign(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 35
Total TN 9491
Total FP 29
Total FP CONTRA 12
Total FP INCONS 15
Total FP COMP 2
Total FN 38
Total Scores
MCC 0.517
Average MCC ± 95% Confidence Intervals 0.474 ± 0.676
Sensitivity 0.479
Positive Predictive Value 0.565
Nr of predictions 3

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2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3E_8 0.19 0.20 0.19 3 2726 13 8 5 0 12
3ZEX_C 0.50 0.45 0.57 13 5351 11 3 7 1 16
4AOB_A 0.73 0.66 0.83 19 1414 5 1 3 1 10

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.