Table of contents:
- Overview
- Performance Plots
- Performance of PETfold_pre2.0(20)
- scored higher in this pairwise comparison
- Performance of NanoFolder
- scored lower in this pairwise comparison
- Compile and download dataset for PETfold_pre2.0(20) & NanoFolder [.zip] - may take several seconds...
Overview
| Metric |
PETfold_pre2.0(20) |
|
NanoFolder |
|---|
| MCC |
0.588 |
>
|
0.314 |
| Average MCC ± 95% Confidence Intervals |
0.570
±
0.277
|
>
|
0.348
±
0.340
|
| Sensitivity |
0.581 |
>
|
0.427 |
| Positive Predictive Value |
0.602 |
>
|
0.242 |
| Total TP |
68 |
>
|
50 |
| Total TN |
14807 |
>
|
14713 |
| Total FP |
70 |
<
|
205 |
| Total FP CONTRA |
12 |
<
|
65 |
| Total FP INCONS |
33 |
<
|
92 |
| Total FP COMP |
25 |
<
|
48 |
| Total FN |
49 |
<
|
67 |
| P-value |
0.0 |
Performance plots
-
Comparison of performance of PETfold_pre2.0(20) and NanoFolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data
(individual counts for PETfold_pre2.0(20)
and NanoFolder).
-
Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data
(individual counts for PETfold_pre2.0(20)
and NanoFolder).
-
Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and NanoFolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data
(individual counts for PETfold_pre2.0(20)
and NanoFolder).
Performance of PETfold_pre2.0(20)
- scored higher in this pairwise comparison
1. Total counts & total scores for PETfold_pre2.0(20)
| Total Base Pair Counts |
|---|
| Total TP |
68 |
| Total TN |
14807 |
| Total FP |
70 |
| Total FP CONTRA |
12 |
| Total FP INCONS |
33 |
| Total FP COMP |
25 |
| Total FN |
49 |
| Total Scores |
|---|
| MCC |
0.588 |
| Average MCC ± 95% Confidence Intervals |
0.570
±
0.277
|
| Sensitivity |
0.581 |
| Positive Predictive Value |
0.602 |
| Nr of predictions |
6 |
Performance of NanoFolder
- scored lower in this pairwise comparison
1. Total counts & total scores for NanoFolder
| Total Base Pair Counts |
|---|
| Total TP |
50 |
| Total TN |
14713 |
| Total FP |
205 |
| Total FP CONTRA |
65 |
| Total FP INCONS |
92 |
| Total FP COMP |
48 |
| Total FN |
67 |
| Total Scores |
|---|
| MCC |
0.314 |
| Average MCC ± 95% Confidence Intervals |
0.348
±
0.340
|
| Sensitivity |
0.427 |
| Positive Predictive Value |
0.242 |
| Nr of predictions |
6 |
Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based
on the paper by Gardener & Giegerich, 2004.
| 
