CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of RDfolder - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & RDfolder [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) RDfolder
MCC 0.826 > 0.595
Average MCC ± 95% Confidence Intervals 0.797 ± 0.178 > 0.591 ± 0.232
Sensitivity 0.778 > 0.545
Positive Predictive Value 0.885 > 0.667
Total TP 77 > 54
Total TN 4505 < 4511
Total FP 12 < 29
Total FP CONTRA 4 < 7
Total FP INCONS 6 < 20
Total FP COMP 2 = 2
Total FN 22 < 45
P-value 0.0

^top




Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and RDfolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and RDfolder).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and RDfolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and RDfolder).

^top





Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 77
Total TN 4505
Total FP 12
Total FP CONTRA 4
Total FP INCONS 6
Total FP COMP 2
Total FN 22
Total Scores
MCC 0.826
Average MCC ± 95% Confidence Intervals 0.797 ± 0.178
Sensitivity 0.778
Positive Predictive Value 0.885
Nr of predictions 5

^top



2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.95 0.95 0.95 20 1198 1 1 0 0 1
3J3D_C 0.87 0.89 0.85 17 948 3 3 0 0 2
4AOB_A 0.87 0.83 0.92 24 1411 4 0 2 2 5
4ENB_A 0.68 0.53 0.89 8 463 1 0 1 0 7
4ENC_A 0.61 0.53 0.73 8 485 3 0 3 0 7

^top



Performance of RDfolder - scored lower in this pairwise comparison

1. Total counts & total scores for RDfolder

Total Base Pair Counts
Total TP 54
Total TN 4511
Total FP 29
Total FP CONTRA 7
Total FP INCONS 20
Total FP COMP 2
Total FN 45
Total Scores
MCC 0.595
Average MCC ± 95% Confidence Intervals 0.591 ± 0.232
Sensitivity 0.545
Positive Predictive Value 0.667
Nr of predictions 5

^top



2. Individual counts for RDfolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.82 0.76 0.89 16 1201 3 1 1 1 5
3J3D_C 0.76 0.79 0.75 15 948 5 3 2 0 4
4AOB_A 0.42 0.38 0.48 11 1414 13 3 9 1 18
4ENB_A 0.48 0.40 0.60 6 462 4 0 4 0 9
4ENC_A 0.48 0.40 0.60 6 486 4 0 4 0 9

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.