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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

  4. Performance of Afold - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(seed) & Afold [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(seed) Afold
MCC 0.698 > 0.454
Average MCC ± 95% Confidence Intervals 0.666 ± 0.200 > 0.489 ± 0.325
Sensitivity 0.624 > 0.495
Positive Predictive Value 0.788 > 0.427
Total TP 63 > 50
Total TN 10167 > 10130
Total FP 36 < 98
Total FP CONTRA 4 < 21
Total FP INCONS 13 < 46
Total FP COMP 19 < 31
Total FN 38 < 51
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(seed) and Afold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and Afold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and Afold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and Afold).

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Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(seed)

Total Base Pair Counts
Total TP 63
Total TN 10167
Total FP 36
Total FP CONTRA 4
Total FP INCONS 13
Total FP COMP 19
Total FN 38
Total Scores
MCC 0.698
Average MCC ± 95% Confidence Intervals 0.666 ± 0.200
Sensitivity 0.624
Positive Predictive Value 0.788
Nr of predictions 5

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2. Individual counts for PETfold_pre2.0(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.41 0.33 0.55 6 517 5 0 5 0 12
3J3E_8 0.71 0.67 0.77 10 2729 8 1 2 5 5
3W3S_B 0.80 0.73 0.89 24 1962 6 1 2 3 9
4A1C_2 0.79 0.75 0.83 15 4498 12 1 2 9 5
4ENB_A 0.61 0.53 0.73 8 461 5 1 2 2 7

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Performance of Afold - scored lower in this pairwise comparison

1. Total counts & total scores for Afold

Total Base Pair Counts
Total TP 50
Total TN 10130
Total FP 98
Total FP CONTRA 21
Total FP INCONS 46
Total FP COMP 31
Total FN 51
Total Scores
MCC 0.454
Average MCC ± 95% Confidence Intervals 0.489 ± 0.325
Sensitivity 0.495
Positive Predictive Value 0.427
Nr of predictions 5

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2. Individual counts for Afold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.64 0.61 0.69 11 512 6 0 5 1 7
3J3E_8 0.26 0.33 0.21 5 2718 31 6 13 12 10
3W3S_B 0.55 0.55 0.56 18 1957 15 4 10 1 15
4A1C_2 0.19 0.25 0.15 5 4483 43 11 17 15 15
4ENB_A 0.81 0.73 0.92 11 460 3 0 1 2 4

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.