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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

  4. Performance of CMfinder(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(seed) & CMfinder(20) [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(seed) CMfinder(20)
MCC 0.869 > 0.580
Average MCC ± 95% Confidence Intervals 0.860 ± 0.110 > 0.564 ± 0.352
Sensitivity 0.857 > 0.500
Positive Predictive Value 0.884 > 0.681
Total TP 84 > 49
Total TN 10797 < 10820
Total FP 30 > 26
Total FP CONTRA 7 < 12
Total FP INCONS 4 < 11
Total FP COMP 19 > 3
Total FN 14 < 49
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(seed) and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and CMfinder(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and CMfinder(20)).

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Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(seed)

Total Base Pair Counts
Total TP 84
Total TN 10797
Total FP 30
Total FP CONTRA 7
Total FP INCONS 4
Total FP COMP 19
Total FN 14
Total Scores
MCC 0.869
Average MCC ± 95% Confidence Intervals 0.860 ± 0.110
Sensitivity 0.857
Positive Predictive Value 0.884
Nr of predictions 5

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2. Individual counts for PETfold_pre2.0(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.95 0.95 0.95 20 1198 2 1 0 1 1
3J3D_C 0.90 0.95 0.86 18 947 4 3 0 1 1
3J3E_8 0.71 0.67 0.77 10 2729 8 1 2 5 5
3J3F_8 0.86 0.84 0.89 16 4743 13 2 0 11 3
4FRG_B 0.87 0.83 0.91 20 1180 3 0 2 1 4

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Performance of CMfinder(20) - scored lower in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 49
Total TN 10820
Total FP 26
Total FP CONTRA 12
Total FP INCONS 11
Total FP COMP 3
Total FN 49
Total Scores
MCC 0.580
Average MCC ± 95% Confidence Intervals 0.564 ± 0.352
Sensitivity 0.500
Positive Predictive Value 0.681
Nr of predictions 5

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.84 0.76 0.94 16 1202 2 1 0 1 5
3J3D_C 0.81 0.79 0.83 15 950 3 3 0 0 4
3J3E_8 0.14 0.13 0.17 2 2730 10 3 7 0 13
3J3F_8 0.48 0.47 0.50 9 4743 11 5 4 2 10
4FRG_B 0.54 0.29 1.00 7 1195 0 0 0 0 17

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.