Table of contents:
- Overview
- Performance Plots
- Performance of PETfold_pre2.0(seed)
- scored higher in this pairwise comparison
- Performance of Fold
- scored lower in this pairwise comparison
- Compile and download dataset for PETfold_pre2.0(seed) & Fold [.zip] - may take several seconds...
Overview
| Metric |
PETfold_pre2.0(seed) |
|
Fold |
|---|
| MCC |
0.831 |
>
|
0.517 |
| Average MCC ± 95% Confidence Intervals |
0.774
±
0.073
|
>
|
0.444
±
0.160
|
| Sensitivity |
0.802 |
>
|
0.544 |
| Positive Predictive Value |
0.863 |
>
|
0.493 |
| Total TP |
603 |
>
|
409 |
| Total TN |
451981 |
>
|
451851 |
| Total FP |
216 |
<
|
538 |
| Total FP CONTRA |
35 |
<
|
98 |
| Total FP INCONS |
61 |
<
|
322 |
| Total FP COMP |
120 |
>
|
118 |
| Total FN |
149 |
<
|
343 |
| P-value |
2.76499031155e-08 |
Performance plots
-
Comparison of performance of PETfold_pre2.0(seed) and Fold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data
(individual counts for PETfold_pre2.0(seed)
and Fold).
-
Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data
(individual counts for PETfold_pre2.0(seed)
and Fold).
-
Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and Fold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data
(individual counts for PETfold_pre2.0(seed)
and Fold).
Performance of PETfold_pre2.0(seed)
- scored higher in this pairwise comparison
1. Total counts & total scores for PETfold_pre2.0(seed)
| Total Base Pair Counts |
|---|
| Total TP |
603 |
| Total TN |
451981 |
| Total FP |
216 |
| Total FP CONTRA |
35 |
| Total FP INCONS |
61 |
| Total FP COMP |
120 |
| Total FN |
149 |
| Total Scores |
|---|
| MCC |
0.831 |
| Average MCC ± 95% Confidence Intervals |
0.774
±
0.073
|
| Sensitivity |
0.802 |
| Positive Predictive Value |
0.863 |
| Nr of predictions |
16 |
Performance of Fold
- scored lower in this pairwise comparison
1. Total counts & total scores for Fold
| Total Base Pair Counts |
|---|
| Total TP |
409 |
| Total TN |
451851 |
| Total FP |
538 |
| Total FP CONTRA |
98 |
| Total FP INCONS |
322 |
| Total FP COMP |
118 |
| Total FN |
343 |
| Total Scores |
|---|
| MCC |
0.517 |
| Average MCC ± 95% Confidence Intervals |
0.444
±
0.160
|
| Sensitivity |
0.544 |
| Positive Predictive Value |
0.493 |
| Nr of predictions |
16 |
Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based
on the paper by Gardener & Giegerich, 2004.
| 
