Table of contents:
- Overview
- Performance Plots
- Performance of PETfold_pre2.0(seed)
- scored higher in this pairwise comparison
- Performance of MCFold
- scored lower in this pairwise comparison
- Compile and download dataset for PETfold_pre2.0(seed) & MCFold [.zip] - may take several seconds...
Overview
Metric |
PETfold_pre2.0(seed) |
|
MCFold |
MCC |
0.772 |
>
|
0.364 |
Average MCC ± 95% Confidence Intervals |
0.752
±
0.096
|
>
|
0.393
±
0.154
|
Sensitivity |
0.709 |
>
|
0.417 |
Positive Predictive Value |
0.845 |
>
|
0.330 |
Total TP |
175 |
>
|
103 |
Total TN |
25001 |
>
|
24896 |
Total FP |
73 |
<
|
261 |
Total FP CONTRA |
14 |
<
|
59 |
Total FP INCONS |
18 |
<
|
150 |
Total FP COMP |
41 |
<
|
52 |
Total FN |
72 |
<
|
144 |
P-value |
1.82627677697e-08 |
Performance plots
-
Comparison of performance of PETfold_pre2.0(seed) and MCFold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data
(individual counts for PETfold_pre2.0(seed)
and MCFold).
-
Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data
(individual counts for PETfold_pre2.0(seed)
and MCFold).
-
Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and MCFold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data
(individual counts for PETfold_pre2.0(seed)
and MCFold).
Performance of PETfold_pre2.0(seed)
- scored higher in this pairwise comparison
1. Total counts & total scores for PETfold_pre2.0(seed)
Total Base Pair Counts |
Total TP |
175 |
Total TN |
25001 |
Total FP |
73 |
Total FP CONTRA |
14 |
Total FP INCONS |
18 |
Total FP COMP |
41 |
Total FN |
72 |
Total Scores |
MCC |
0.772 |
Average MCC ± 95% Confidence Intervals |
0.752
±
0.096
|
Sensitivity |
0.709 |
Positive Predictive Value |
0.845 |
Nr of predictions |
12 |
Performance of MCFold
- scored lower in this pairwise comparison
1. Total counts & total scores for MCFold
Total Base Pair Counts |
Total TP |
103 |
Total TN |
24896 |
Total FP |
261 |
Total FP CONTRA |
59 |
Total FP INCONS |
150 |
Total FP COMP |
52 |
Total FN |
144 |
Total Scores |
MCC |
0.364 |
Average MCC ± 95% Confidence Intervals |
0.393
±
0.154
|
Sensitivity |
0.417 |
Positive Predictive Value |
0.330 |
Nr of predictions |
12 |
Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based
on the paper by Gardener & Giegerich, 2004.
|