CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PPfold(20) - scored higher in this pairwise comparison

  4. Performance of CMfinder(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for PPfold(20) & CMfinder(20) [.zip] - may take several seconds...


Overview

Metric PPfold(20) CMfinder(20)
MCC 0.682 > 0.580
Average MCC ± 95% Confidence Intervals 0.648 ± 0.416 > 0.564 ± 0.352
Sensitivity 0.663 > 0.500
Positive Predictive Value 0.707 > 0.681
Total TP 65 > 49
Total TN 10800 < 10820
Total FP 38 > 26
Total FP CONTRA 11 < 12
Total FP INCONS 16 > 11
Total FP COMP 11 > 3
Total FN 33 < 49
P-value 0.0

^top




Performance plots


  1. Comparison of performance of PPfold(20) and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PPfold(20) and CMfinder(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PPfold(20) and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PPfold(20) and CMfinder(20)).

^top





Performance of PPfold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PPfold(20)

Total Base Pair Counts
Total TP 65
Total TN 10800
Total FP 38
Total FP CONTRA 11
Total FP INCONS 16
Total FP COMP 11
Total FN 33
Total Scores
MCC 0.682
Average MCC ± 95% Confidence Intervals 0.648 ± 0.416
Sensitivity 0.663
Positive Predictive Value 0.707
Nr of predictions 5

^top



2. Individual counts for PPfold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.95 0.95 0.95 20 1198 1 1 0 0 1
3J3D_C 0.87 0.89 0.85 17 948 3 3 0 0 2
3J3E_8 0.21 0.20 0.23 3 2729 13 2 8 3 12
3J3F_8 0.37 0.37 0.37 7 4742 20 5 7 8 12
4FRG_B 0.84 0.75 0.95 18 1183 1 0 1 0 6

^top



Performance of CMfinder(20) - scored lower in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 49
Total TN 10820
Total FP 26
Total FP CONTRA 12
Total FP INCONS 11
Total FP COMP 3
Total FN 49
Total Scores
MCC 0.580
Average MCC ± 95% Confidence Intervals 0.564 ± 0.352
Sensitivity 0.500
Positive Predictive Value 0.681
Nr of predictions 5

^top



2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.84 0.76 0.94 16 1202 2 1 0 1 5
3J3D_C 0.81 0.79 0.83 15 950 3 3 0 0 4
3J3E_8 0.14 0.13 0.17 2 2730 10 3 7 0 13
3J3F_8 0.48 0.47 0.50 9 4743 11 5 4 2 10
4FRG_B 0.54 0.29 1.00 7 1195 0 0 0 0 17

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.