CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PPfold(20) - scored higher in this pairwise comparison

  4. Performance of CRWrnafold - scored lower in this pairwise comparison

  5. Compile and download dataset for PPfold(20) & CRWrnafold [.zip] - may take several seconds...


Overview

Metric PPfold(20) CRWrnafold
MCC 0.681 > 0.592
Average MCC ± 95% Confidence Intervals 0.646 ± 0.293 < 0.646 ± 0.339
Sensitivity 0.611 = 0.611
Positive Predictive Value 0.767 > 0.584
Total TP 66 = 66
Total TN 8368 > 8341
Total FP 26 < 68
Total FP CONTRA 3 < 18
Total FP INCONS 17 < 29
Total FP COMP 6 < 21
Total FN 42 = 42
P-value 0.0

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Performance plots


  1. Comparison of performance of PPfold(20) and CRWrnafold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PPfold(20) and CRWrnafold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PPfold(20) and CRWrnafold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PPfold(20) and CRWrnafold).

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Performance of PPfold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PPfold(20)

Total Base Pair Counts
Total TP 66
Total TN 8368
Total FP 26
Total FP CONTRA 3
Total FP INCONS 17
Total FP COMP 6
Total FN 42
Total Scores
MCC 0.681
Average MCC ± 95% Confidence Intervals 0.646 ± 0.293
Sensitivity 0.611
Positive Predictive Value 0.767
Nr of predictions 5

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2. Individual counts for PPfold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3SD1_A 0.81 0.76 0.88 22 1508 3 2 1 0 7
4A1C_2 0.27 0.25 0.29 5 4499 16 1 11 4 15
4AOB_A 0.87 0.83 0.92 24 1411 4 0 2 2 5
4ENB_A 0.63 0.47 0.88 7 464 1 0 1 0 8
4ENC_A 0.64 0.53 0.80 8 486 2 0 2 0 7

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Performance of CRWrnafold - scored lower in this pairwise comparison

1. Total counts & total scores for CRWrnafold

Total Base Pair Counts
Total TP 66
Total TN 8341
Total FP 68
Total FP CONTRA 18
Total FP INCONS 29
Total FP COMP 21
Total FN 42
Total Scores
MCC 0.592
Average MCC ± 95% Confidence Intervals 0.646 ± 0.339
Sensitivity 0.611
Positive Predictive Value 0.584
Nr of predictions 5

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2. Individual counts for CRWrnafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3SD1_A 0.63 0.66 0.61 19 1502 12 6 6 0 10
4A1C_2 0.19 0.25 0.15 5 4483 44 8 20 16 15
4AOB_A 0.71 0.69 0.74 20 1410 8 4 3 1 9
4ENB_A 0.85 0.73 1.00 11 461 2 0 0 2 4
4ENC_A 0.85 0.73 1.00 11 485 2 0 0 2 4

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.