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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASLOpt - scored higher in this pairwise comparison

  4. Performance of Alterna - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASLOpt & Alterna [.zip] - may take several seconds...


Overview

Metric RNASLOpt Alterna
MCC 0.379 > 0.362
Average MCC ± 95% Confidence Intervals 0.348 ± 1.733 > 0.326 ± 1.837
Sensitivity 0.310 < 0.345
Positive Predictive Value 0.500 > 0.417
Total TP 9 < 10
Total TN 921 > 915
Total FP 10 < 15
Total FP CONTRA 3 = 3
Total FP INCONS 6 < 11
Total FP COMP 1 = 1
Total FN 20 > 19
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASLOpt and Alterna. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASLOpt and Alterna).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASLOpt and Alterna. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASLOpt and Alterna).

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Performance of RNASLOpt - scored higher in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 9
Total TN 921
Total FP 10
Total FP CONTRA 3
Total FP INCONS 6
Total FP COMP 1
Total FN 20
Total Scores
MCC 0.379
Average MCC ± 95% Confidence Intervals 0.348 ± 1.733
Sensitivity 0.310
Positive Predictive Value 0.500
Nr of predictions 2

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.48 0.39 0.64 7 517 4 0 4 0 11
3J0L_a - 0.21 0.18 0.29 2 404 6 3 2 1 9

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Performance of Alterna - scored lower in this pairwise comparison

1. Total counts & total scores for Alterna

Total Base Pair Counts
Total TP 10
Total TN 915
Total FP 15
Total FP CONTRA 3
Total FP INCONS 11
Total FP COMP 1
Total FN 19
Total Scores
MCC 0.362
Average MCC ± 95% Confidence Intervals 0.326 ± 1.837
Sensitivity 0.345
Positive Predictive Value 0.417
Nr of predictions 2

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2. Individual counts for Alterna [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.47 0.44 0.53 8 513 7 0 7 0 10
3J0L_a - 0.18 0.18 0.22 2 402 8 3 4 1 9

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.