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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(20) - scored higher in this pairwise comparison

  4. Performance of CMfinder(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(20) & CMfinder(20) [.zip] - may take several seconds...


Overview

Metric RNASampler(20) CMfinder(20)
MCC 0.629 > 0.580
Average MCC ± 95% Confidence Intervals 0.611 ± 0.383 > 0.564 ± 0.352
Sensitivity 0.633 > 0.500
Positive Predictive Value 0.633 < 0.681
Total TP 62 > 49
Total TN 10794 < 10820
Total FP 51 > 26
Total FP CONTRA 15 > 12
Total FP INCONS 21 > 11
Total FP COMP 15 > 3
Total FN 36 < 49
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(20) and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(20) and CMfinder(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(20) and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(20) and CMfinder(20)).

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Performance of RNASampler(20) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(20)

Total Base Pair Counts
Total TP 62
Total TN 10794
Total FP 51
Total FP CONTRA 15
Total FP INCONS 21
Total FP COMP 15
Total FN 36
Total Scores
MCC 0.629
Average MCC ± 95% Confidence Intervals 0.611 ± 0.383
Sensitivity 0.633
Positive Predictive Value 0.633
Nr of predictions 5

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2. Individual counts for RNASampler(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.90 0.90 0.90 19 1198 3 1 1 1 2
3J3D_C 0.90 0.95 0.86 18 947 3 3 0 0 1
3J3E_8 0.19 0.20 0.19 3 2726 21 5 8 8 12
3J3F_8 0.43 0.47 0.39 9 4738 20 6 8 6 10
4FRG_B 0.64 0.54 0.76 13 1185 4 0 4 0 11

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Performance of CMfinder(20) - scored lower in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 49
Total TN 10820
Total FP 26
Total FP CONTRA 12
Total FP INCONS 11
Total FP COMP 3
Total FN 49
Total Scores
MCC 0.580
Average MCC ± 95% Confidence Intervals 0.564 ± 0.352
Sensitivity 0.500
Positive Predictive Value 0.681
Nr of predictions 5

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.84 0.76 0.94 16 1202 2 1 0 1 5
3J3D_C 0.81 0.79 0.83 15 950 3 3 0 0 4
3J3E_8 0.14 0.13 0.17 2 2730 10 3 7 0 13
3J3F_8 0.48 0.47 0.50 9 4743 11 5 4 2 10
4FRG_B 0.54 0.29 1.00 7 1195 0 0 0 0 17

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.