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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(seed) - scored higher in this pairwise comparison

  4. Performance of CRWrnafold - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(seed) & CRWrnafold [.zip] - may take several seconds...


Overview

Metric RNASampler(seed) CRWrnafold
MCC 0.423 > 0.322
Average MCC ± 95% Confidence Intervals 0.363 ± 0.925 > 0.262 ± 0.831
Sensitivity 0.358 = 0.358
Positive Predictive Value 0.511 > 0.304
Total TP 24 = 24
Total TN 6530 > 6498
Total FP 31 < 71
Total FP CONTRA 4 < 17
Total FP INCONS 19 < 38
Total FP COMP 8 < 16
Total FN 43 = 43
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(seed) and CRWrnafold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(seed) and CRWrnafold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(seed) and CRWrnafold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(seed) and CRWrnafold).

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Performance of RNASampler(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 24
Total TN 6530
Total FP 31
Total FP CONTRA 4
Total FP INCONS 19
Total FP COMP 8
Total FN 43
Total Scores
MCC 0.423
Average MCC ± 95% Confidence Intervals 0.363 ± 0.925
Sensitivity 0.358
Positive Predictive Value 0.511
Nr of predictions 3

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 518 10 0 10 0 18
3SD1_A 0.72 0.55 0.94 16 1516 1 0 1 0 13
4A1C_2 0.40 0.40 0.40 8 4496 20 4 8 8 12

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Performance of CRWrnafold - scored lower in this pairwise comparison

1. Total counts & total scores for CRWrnafold

Total Base Pair Counts
Total TP 24
Total TN 6498
Total FP 71
Total FP CONTRA 17
Total FP INCONS 38
Total FP COMP 16
Total FN 43
Total Scores
MCC 0.322
Average MCC ± 95% Confidence Intervals 0.262 ± 0.831
Sensitivity 0.358
Positive Predictive Value 0.304
Nr of predictions 3

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2. Individual counts for CRWrnafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 513 15 3 12 0 18
3SD1_A 0.63 0.66 0.61 19 1502 12 6 6 0 10
4A1C_2 0.19 0.25 0.15 5 4483 44 8 20 16 15

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.