CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(seed) - scored higher in this pairwise comparison

  4. Performance of RDfolder - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(seed) & RDfolder [.zip] - may take several seconds...


Overview

Metric RNASampler(seed) RDfolder
MCC 0.688 > 0.515
Average MCC ± 95% Confidence Intervals 0.647 ± 0.367 > 0.504 ± 0.389
Sensitivity 0.541 > 0.446
Positive Predictive Value 0.885 > 0.614
Total TP 85 > 70
Total TN 7223 > 7205
Total FP 12 < 44
Total FP CONTRA 0 < 6
Total FP INCONS 11 < 38
Total FP COMP 1 > 0
Total FN 72 < 87
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(seed) and RDfolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(seed) and RDfolder).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(seed) and RDfolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(seed) and RDfolder).

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Performance of RNASampler(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 85
Total TN 7223
Total FP 12
Total FP CONTRA 0
Total FP INCONS 11
Total FP COMP 1
Total FN 72
Total Scores
MCC 0.688
Average MCC ± 95% Confidence Intervals 0.647 ± 0.367
Sensitivity 0.541
Positive Predictive Value 0.885
Nr of predictions 6

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 518 10 0 10 0 18
3A3A_A 0.77 0.60 1.00 18 1482 0 0 0 0 12
3IVN_B 0.91 0.83 1.00 19 884 0 0 0 0 4
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.72 0.55 0.94 16 1516 1 0 1 0 13
3W3S_B 0.60 0.36 1.00 12 1977 1 0 0 1 21

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Performance of RDfolder - scored lower in this pairwise comparison

1. Total counts & total scores for RDfolder

Total Base Pair Counts
Total TP 70
Total TN 7205
Total FP 44
Total FP CONTRA 6
Total FP INCONS 38
Total FP COMP 0
Total FN 87
Total Scores
MCC 0.515
Average MCC ± 95% Confidence Intervals 0.504 ± 0.389
Sensitivity 0.446
Positive Predictive Value 0.614
Nr of predictions 6

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2. Individual counts for RDfolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 514 14 3 11 0 18
3A3A_A 0.59 0.50 0.71 15 1479 6 0 6 0 15
3IVN_B 0.91 0.83 1.00 19 884 0 0 0 0 4
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.35 0.24 0.54 7 1520 6 1 5 0 22
3W3S_B 0.29 0.27 0.33 9 1962 18 2 16 0 24

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.