CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(seed) - scored higher in this pairwise comparison

  4. Performance of TurboFold(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(seed) & TurboFold(20) [.zip] - may take several seconds...


Overview

Metric RNASampler(seed) TurboFold(20)
MCC 0.526 > 0.515
Average MCC ± 95% Confidence Intervals 0.512 ± 0.273 > 0.505 ± 0.276
Sensitivity 0.478 < 0.537
Positive Predictive Value 0.586 > 0.500
Total TP 65 < 73
Total TN 19681 > 19646
Total FP 75 < 115
Total FP CONTRA 16 < 25
Total FP INCONS 30 < 48
Total FP COMP 29 < 42
Total FN 71 > 63
P-value 0.0

^top




Performance plots


  1. Comparison of performance of RNASampler(seed) and TurboFold(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(seed) and TurboFold(20)).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for RNASampler(seed) and TurboFold(20)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(seed) and TurboFold(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(seed) and TurboFold(20)).

^top





Performance of RNASampler(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 65
Total TN 19681
Total FP 75
Total FP CONTRA 16
Total FP INCONS 30
Total FP COMP 29
Total FN 71
Total Scores
MCC 0.526
Average MCC ± 95% Confidence Intervals 0.512 ± 0.273
Sensitivity 0.478
Positive Predictive Value 0.586
Nr of predictions 6

^top



2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3E_8 0.18 0.20 0.18 3 2725 22 5 9 8 12
3J3F_8 0.47 0.47 0.47 9 4742 18 5 5 8 10
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.72 0.55 0.94 16 1516 1 0 1 0 13
3ZEX_C 0.39 0.31 0.50 9 5356 14 2 7 5 20
4A1C_2 0.40 0.40 0.40 8 4496 20 4 8 8 12

^top



Performance of TurboFold(20) - scored lower in this pairwise comparison

1. Total counts & total scores for TurboFold(20)

Total Base Pair Counts
Total TP 73
Total TN 19646
Total FP 115
Total FP CONTRA 25
Total FP INCONS 48
Total FP COMP 42
Total FN 63
Total Scores
MCC 0.515
Average MCC ± 95% Confidence Intervals 0.505 ± 0.276
Sensitivity 0.537
Positive Predictive Value 0.500
Nr of predictions 6

^top



2. Individual counts for TurboFold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3E_8 0.27 0.33 0.23 5 2720 28 6 11 11 10
3J3F_8 0.42 0.53 0.34 10 4732 37 9 10 18 9
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.71 0.69 0.74 20 1506 7 2 5 0 9
3ZEX_C 0.49 0.45 0.54 13 5350 15 2 9 4 16
4A1C_2 0.22 0.25 0.21 5 4492 28 6 13 9 15

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.