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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNAalifold(20) - scored higher in this pairwise comparison

  4. Performance of CRWrnafold - scored lower in this pairwise comparison

  5. Compile and download dataset for RNAalifold(20) & CRWrnafold [.zip] - may take several seconds...


Overview

Metric RNAalifold(20) CRWrnafold
MCC 0.625 > 0.592
Average MCC ± 95% Confidence Intervals 0.609 ± 0.327 < 0.646 ± 0.339
Sensitivity 0.565 < 0.611
Positive Predictive Value 0.701 > 0.584
Total TP 61 < 66
Total TN 8367 > 8341
Total FP 30 < 68
Total FP CONTRA 9 < 18
Total FP INCONS 17 < 29
Total FP COMP 4 < 21
Total FN 47 > 42
P-value 0.0

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Performance plots


  1. Comparison of performance of RNAalifold(20) and CRWrnafold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNAalifold(20) and CRWrnafold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNAalifold(20) and CRWrnafold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNAalifold(20) and CRWrnafold).

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Performance of RNAalifold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for RNAalifold(20)

Total Base Pair Counts
Total TP 61
Total TN 8367
Total FP 30
Total FP CONTRA 9
Total FP INCONS 17
Total FP COMP 4
Total FN 47
Total Scores
MCC 0.625
Average MCC ± 95% Confidence Intervals 0.609 ± 0.327
Sensitivity 0.565
Positive Predictive Value 0.701
Nr of predictions 5

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2. Individual counts for RNAalifold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3SD1_A 0.84 0.86 0.83 25 1503 5 4 1 0 4
4A1C_2 0.22 0.25 0.19 5 4490 23 5 16 2 15
4AOB_A 0.85 0.72 1.00 21 1416 2 0 0 2 8
4ENB_A 0.51 0.27 1.00 4 468 0 0 0 0 11
4ENC_A 0.63 0.40 1.00 6 490 0 0 0 0 9

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Performance of CRWrnafold - scored lower in this pairwise comparison

1. Total counts & total scores for CRWrnafold

Total Base Pair Counts
Total TP 66
Total TN 8341
Total FP 68
Total FP CONTRA 18
Total FP INCONS 29
Total FP COMP 21
Total FN 42
Total Scores
MCC 0.592
Average MCC ± 95% Confidence Intervals 0.646 ± 0.339
Sensitivity 0.611
Positive Predictive Value 0.584
Nr of predictions 5

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2. Individual counts for CRWrnafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3SD1_A 0.63 0.66 0.61 19 1502 12 6 6 0 10
4A1C_2 0.19 0.25 0.15 5 4483 44 8 20 16 15
4AOB_A 0.71 0.69 0.74 20 1410 8 4 3 1 9
4ENB_A 0.85 0.73 1.00 11 461 2 0 0 2 4
4ENC_A 0.85 0.73 1.00 11 485 2 0 0 2 4

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.