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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(20) - scored higher in this pairwise comparison

  4. Performance of CMfinder(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(20) & CMfinder(20) [.zip] - may take several seconds...


Overview

Metric TurboFold(20) CMfinder(20)
MCC 0.656 > 0.580
Average MCC ± 95% Confidence Intervals 0.653 ± 0.365 > 0.564 ± 0.352
Sensitivity 0.714 > 0.500
Positive Predictive Value 0.609 < 0.681
Total TP 70 > 49
Total TN 10777 < 10820
Total FP 75 > 26
Total FP CONTRA 19 > 12
Total FP INCONS 26 > 11
Total FP COMP 30 > 3
Total FN 28 < 49
P-value 0.0

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Performance plots


  1. Comparison of performance of TurboFold(20) and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and CMfinder(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and CMfinder(20)).

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Performance of TurboFold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(20)

Total Base Pair Counts
Total TP 70
Total TN 10777
Total FP 75
Total FP CONTRA 19
Total FP INCONS 26
Total FP COMP 30
Total FN 28
Total Scores
MCC 0.656
Average MCC ± 95% Confidence Intervals 0.653 ± 0.365
Sensitivity 0.714
Positive Predictive Value 0.609
Nr of predictions 5

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2. Individual counts for TurboFold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.74 0.76 0.73 16 1197 7 1 5 1 5
3J3D_C 0.90 0.95 0.86 18 947 3 3 0 0 1
3J3E_8 0.27 0.33 0.23 5 2720 28 6 11 11 10
3J3F_8 0.42 0.53 0.34 10 4732 37 9 10 18 9
4FRG_B 0.93 0.88 1.00 21 1181 0 0 0 0 3

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Performance of CMfinder(20) - scored lower in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 49
Total TN 10820
Total FP 26
Total FP CONTRA 12
Total FP INCONS 11
Total FP COMP 3
Total FN 49
Total Scores
MCC 0.580
Average MCC ± 95% Confidence Intervals 0.564 ± 0.352
Sensitivity 0.500
Positive Predictive Value 0.681
Nr of predictions 5

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.84 0.76 0.94 16 1202 2 1 0 1 5
3J3D_C 0.81 0.79 0.83 15 950 3 3 0 0 4
3J3E_8 0.14 0.13 0.17 2 2730 10 3 7 0 13
3J3F_8 0.48 0.47 0.50 9 4743 11 5 4 2 10
4FRG_B 0.54 0.29 1.00 7 1195 0 0 0 0 17

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.