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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(20) - scored higher in this pairwise comparison

  4. Performance of CRWrnafold - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(20) & CRWrnafold [.zip] - may take several seconds...


Overview

Metric TurboFold(20) CRWrnafold
MCC 0.597 > 0.592
Average MCC ± 95% Confidence Intervals 0.620 ± 0.278 < 0.646 ± 0.339
Sensitivity 0.556 < 0.611
Positive Predictive Value 0.652 > 0.584
Total TP 60 < 66
Total TN 8362 > 8341
Total FP 42 < 68
Total FP CONTRA 11 < 18
Total FP INCONS 21 < 29
Total FP COMP 10 < 21
Total FN 48 > 42
P-value 0.0

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Performance plots


  1. Comparison of performance of TurboFold(20) and CRWrnafold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and CRWrnafold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and CRWrnafold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and CRWrnafold).

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Performance of TurboFold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(20)

Total Base Pair Counts
Total TP 60
Total TN 8362
Total FP 42
Total FP CONTRA 11
Total FP INCONS 21
Total FP COMP 10
Total FN 48
Total Scores
MCC 0.597
Average MCC ± 95% Confidence Intervals 0.620 ± 0.278
Sensitivity 0.556
Positive Predictive Value 0.652
Nr of predictions 5

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2. Individual counts for TurboFold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3SD1_A 0.71 0.69 0.74 20 1506 7 2 5 0 9
4A1C_2 0.22 0.25 0.21 5 4492 28 6 13 9 15
4AOB_A 0.67 0.59 0.77 17 1415 6 2 3 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Performance of CRWrnafold - scored lower in this pairwise comparison

1. Total counts & total scores for CRWrnafold

Total Base Pair Counts
Total TP 66
Total TN 8341
Total FP 68
Total FP CONTRA 18
Total FP INCONS 29
Total FP COMP 21
Total FN 42
Total Scores
MCC 0.592
Average MCC ± 95% Confidence Intervals 0.646 ± 0.339
Sensitivity 0.611
Positive Predictive Value 0.584
Nr of predictions 5

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2. Individual counts for CRWrnafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3SD1_A 0.63 0.66 0.61 19 1502 12 6 6 0 10
4A1C_2 0.19 0.25 0.15 5 4483 44 8 20 16 15
4AOB_A 0.71 0.69 0.74 20 1410 8 4 3 1 9
4ENB_A 0.85 0.73 1.00 11 461 2 0 0 2 4
4ENC_A 0.85 0.73 1.00 11 485 2 0 0 2 4

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.