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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(seed) - scored higher in this pairwise comparison

  4. Performance of CMfinder(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(seed) & CMfinder(20) [.zip] - may take several seconds...


Overview

Metric TurboFold(seed) CMfinder(20)
MCC 0.357 > 0.342
Average MCC ± 95% Confidence Intervals 0.347 ± 0.971 > 0.315 ± 2.159
Sensitivity 0.441 > 0.324
Positive Predictive Value 0.294 < 0.367
Total TP 15 > 11
Total TN 7452 < 7473
Total FP 63 > 21
Total FP CONTRA 15 > 8
Total FP INCONS 21 > 11
Total FP COMP 27 > 2
Total FN 19 < 23
P-value 0.0

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Performance plots


  1. Comparison of performance of TurboFold(seed) and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(seed) and CMfinder(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(seed) and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(seed) and CMfinder(20)).

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Performance of TurboFold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(seed)

Total Base Pair Counts
Total TP 15
Total TN 7452
Total FP 63
Total FP CONTRA 15
Total FP INCONS 21
Total FP COMP 27
Total FN 19
Total Scores
MCC 0.357
Average MCC ± 95% Confidence Intervals 0.347 ± 0.971
Sensitivity 0.441
Positive Predictive Value 0.294
Nr of predictions 2

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2. Individual counts for TurboFold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3E_8 0.27 0.33 0.23 5 2720 28 6 11 11 10
3J3F_8 0.42 0.53 0.34 10 4732 35 9 10 16 9

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Performance of CMfinder(20) - scored lower in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 11
Total TN 7473
Total FP 21
Total FP CONTRA 8
Total FP INCONS 11
Total FP COMP 2
Total FN 23
Total Scores
MCC 0.342
Average MCC ± 95% Confidence Intervals 0.315 ± 2.159
Sensitivity 0.324
Positive Predictive Value 0.367
Nr of predictions 2

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3E_8 0.14 0.13 0.17 2 2730 10 3 7 0 13
3J3F_8 0.48 0.47 0.50 9 4743 11 5 4 2 10

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.