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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CMfinder(20) - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for CMfinder(20) & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric CMfinder(20) Carnac(seed)
MCC 0.333 > 0.000
Average MCC ± 95% Confidence Intervals 0.337 ± 0.514 > 0.000 ± 0.000
Sensitivity 0.208 > 0.000
Positive Predictive Value 0.538 > 0.000
Total TP 21 > 0
Total TN 23196 < 23235
Total FP 18 > 0
Total FP CONTRA 2 > 0
Total FP INCONS 16 > 0
Total FP COMP 0 = 0
Total FN 80 < 101
P-value 0.0

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Performance plots


  1. Comparison of performance of CMfinder(20) and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CMfinder(20) and Carnac(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CMfinder(20) and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CMfinder(20) and Carnac(seed)).

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Performance of CMfinder(20) - scored higher in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 21
Total TN 23196
Total FP 18
Total FP CONTRA 2
Total FP INCONS 16
Total FP COMP 0
Total FN 80
Total Scores
MCC 0.333
Average MCC ± 95% Confidence Intervals 0.337 ± 0.514
Sensitivity 0.208
Positive Predictive Value 0.538
Nr of predictions 3

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3E_8 0.10 0.06 0.17 2 7491 10 1 9 0 31
3J3F_8 0.45 0.33 0.60 12 12226 8 1 7 0 24
4FRG_B 0.47 0.22 1.00 7 3479 0 0 0 0 25

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Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 0
Total TN 23235
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 101
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ± 0.000
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 3

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2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3E_8 0.00 0.00 0.00 0 7503 0 0 0 0 33
3J3F_8 0.00 0.00 0.00 0 12246 0 0 0 0 36
4FRG_B 0.00 0.00 0.00 0 3486 0 0 0 0 32

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.