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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CMfinder(20) - scored higher in this pairwise comparison

  4. Performance of RDfolder - scored lower in this pairwise comparison

  5. Compile and download dataset for CMfinder(20) & RDfolder [.zip] - may take several seconds...


Overview

Metric CMfinder(20) RDfolder
MCC 0.753 > 0.722
Average MCC ± 95% Confidence Intervals 0.753 ± 0.028 > 0.723 ± 0.086
Sensitivity 0.586 = 0.586
Positive Predictive Value 0.971 > 0.895
Total TP 34 = 34
Total TN 5590 > 5587
Total FP 2 < 5
Total FP CONTRA 0 = 0
Total FP INCONS 1 < 4
Total FP COMP 1 = 1
Total FN 24 = 24
P-value 0.0

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Performance plots


  1. Comparison of performance of CMfinder(20) and RDfolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CMfinder(20) and RDfolder).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CMfinder(20) and RDfolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CMfinder(20) and RDfolder).

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Performance of CMfinder(20) - scored higher in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 34
Total TN 5590
Total FP 2
Total FP CONTRA 0
Total FP INCONS 1
Total FP COMP 1
Total FN 24
Total Scores
MCC 0.753
Average MCC ± 95% Confidence Intervals 0.753 ± 0.028
Sensitivity 0.586
Positive Predictive Value 0.971
Nr of predictions 2

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.75 0.57 1.00 17 2833 1 0 0 1 13
3J3D_C 0.76 0.61 0.94 17 2757 1 0 1 0 11

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Performance of RDfolder - scored lower in this pairwise comparison

1. Total counts & total scores for RDfolder

Total Base Pair Counts
Total TP 34
Total TN 5587
Total FP 5
Total FP CONTRA 0
Total FP INCONS 4
Total FP COMP 1
Total FN 24
Total Scores
MCC 0.722
Average MCC ± 95% Confidence Intervals 0.723 ± 0.086
Sensitivity 0.586
Positive Predictive Value 0.895
Nr of predictions 2

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2. Individual counts for RDfolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.73 0.57 0.94 17 2832 2 0 1 1 13
3J3D_C 0.72 0.61 0.85 17 2755 3 0 3 0 11

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.