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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CMfinder(20) - scored higher in this pairwise comparison

  4. Performance of RNASampler(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for CMfinder(20) & RNASampler(seed) [.zip] - may take several seconds...


Overview

Metric CMfinder(20) RNASampler(seed)
MCC 0.296 > 0.287
Average MCC ± 95% Confidence Intervals 0.272 ± 2.210 < 0.278 ± 2.001
Sensitivity 0.203 < 0.217
Positive Predictive Value 0.438 > 0.385
Total TP 14 < 15
Total TN 19717 > 19710
Total FP 18 < 37
Total FP CONTRA 2 < 3
Total FP INCONS 16 < 21
Total FP COMP 0 < 13
Total FN 55 > 54
P-value 0.0

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Performance plots


  1. Comparison of performance of CMfinder(20) and RNASampler(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CMfinder(20) and RNASampler(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CMfinder(20) and RNASampler(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CMfinder(20) and RNASampler(seed)).

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Performance of CMfinder(20) - scored higher in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 14
Total TN 19717
Total FP 18
Total FP CONTRA 2
Total FP INCONS 16
Total FP COMP 0
Total FN 55
Total Scores
MCC 0.296
Average MCC ± 95% Confidence Intervals 0.272 ± 2.210
Sensitivity 0.203
Positive Predictive Value 0.438
Nr of predictions 2

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3E_8 0.10 0.06 0.17 2 7491 10 1 9 0 31
3J3F_8 0.45 0.33 0.60 12 12226 8 1 7 0 24

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Performance of RNASampler(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 15
Total TN 19710
Total FP 37
Total FP CONTRA 3
Total FP INCONS 21
Total FP COMP 13
Total FN 54
Total Scores
MCC 0.287
Average MCC ± 95% Confidence Intervals 0.278 ± 2.001
Sensitivity 0.217
Positive Predictive Value 0.385
Nr of predictions 2

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3E_8 0.12 0.09 0.17 3 7485 22 2 13 7 30
3J3F_8 0.44 0.33 0.57 12 12225 15 1 8 6 24

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.