CompaRNA - on-line benchmarks of RNA structure prediction methods

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Metric	CRWrnafold		NanoFolder
MCC	0.492	>	0.366
Average MCC ± 95% Confidence Intervals	0.482 ± 0.246	>	0.394 ± 0.166
Sensitivity	0.431	>	0.380
Positive Predictive Value	0.570	>	0.362
Total TP	118	>	104
Total TN	37991	>	37911
Total FP	101	<	193
Total FP CONTRA	11	<	27
Total FP INCONS	78	<	156
Total FP COMP	12	>	10
Total FN	156	<	170
P-value	0.0

Comparison of performance of CRWrnafold and NanoFolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CRWrnafold and NanoFolder).
Comparison of average Matthews Correlation Coefficients (MCCs) for CRWrnafold and NanoFolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CRWrnafold and NanoFolder).

Total Scores
MCC	0.492
Average MCC ± 95% Confidence Intervals	0.482 ± 0.246
Sensitivity	0.431
Positive Predictive Value	0.570
Nr of predictions	8

RNA Chain	Rfam family	MCC	SENS	PPV	TP	TN	FP	FP CONTRA	FP INCONS	FP COMP	FN
2LC8_A	GP_knot1 links to Rfam database...	-0.01	0.00	0.00	0	1525	15	2	13	0	20
2LKR_A	-	0.52	0.44	0.63	17	6078	12	2	8	2	22
3J16_L	tRNA links to Rfam database...	0.84	0.70	1.00	21	2754	0	0	0	0	9
3U4M_B	-	0.38	0.32	0.46	12	3134	14	0	14	0	25
4A1C_3	5S_rRNA links to Rfam database...	0.70	0.59	0.84	32	7102	6	0	6	0	22
4A1C_2	5_8S_rRNA links to Rfam database...	0.13	0.15	0.13	5	11741	44	4	31	9	28
4AOB_A	SAM links to Rfam database...	0.59	0.48	0.74	20	4344	8	2	5	1	22
4ENC_A	crcB links to Rfam database...	0.70	0.58	0.85	11	1313	2	1	1	0	8

Total Scores
MCC	0.366
Average MCC ± 95% Confidence Intervals	0.394 ± 0.166
Sensitivity	0.380
Positive Predictive Value	0.362
Nr of predictions	8

RNA Chain	Rfam family	MCC	SENS	PPV	TP	TN	FP	FP CONTRA	FP INCONS	FP COMP	FN
2LC8_A	GP_knot1 links to Rfam database...	0.52	0.55	0.50	11	1518	11	0	11	0	9
2LKR_A	-	0.29	0.33	0.25	13	6054	38	8	30	0	26
3J16_L	tRNA links to Rfam database...	0.36	0.37	0.37	11	2745	19	3	16	0	19
3U4M_B	-	0.61	0.57	0.66	21	3128	11	1	10	0	16
4A1C_3	5S_rRNA links to Rfam database...	0.48	0.46	0.51	25	7091	24	2	22	0	29
4A1C_2	5_8S_rRNA links to Rfam database...	0.00	0.00	0.00	0	11728	61	12	41	8	33
4AOB_A	SAM links to Rfam database...	0.33	0.29	0.39	12	4340	20	1	18	1	30
4ENC_A	crcB links to Rfam database...	0.57	0.58	0.58	11	1307	9	0	8	1	8

Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.