CompaRNA - on-line benchmarks of RNA structure prediction methods

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Metric	CRWrnafold		TurboFold(seed)
MCC	0.483	>	0.483
Average MCC ± 95% Confidence Intervals	0.476 ± 0.272	>	0.473 ± 0.263
Sensitivity	0.428	>	0.397
Positive Predictive Value	0.554	<	0.595
Total TP	98	>	91
Total TN	31172	<	31196
Total FP	89	>	72
Total FP CONTRA	12	>	8
Total FP INCONS	67	>	54
Total FP COMP	10	=	10
Total FN	131	<	138
P-value	0.0

Comparison of performance of CRWrnafold and TurboFold(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CRWrnafold and TurboFold(seed)).
Comparison of average Matthews Correlation Coefficients (MCCs) for CRWrnafold and TurboFold(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CRWrnafold and TurboFold(seed)).

Total Scores
MCC	0.483
Average MCC ± 95% Confidence Intervals	0.476 ± 0.272
Sensitivity	0.428
Positive Predictive Value	0.554
Nr of predictions	7

RNA Chain	Rfam family	MCC	SENS	PPV	TP	TN	FP	FP CONTRA	FP INCONS	FP COMP	FN
2LC8_A	GP_knot1 links to Rfam database...	-0.01	0.00	0.00	0	1525	15	2	13	0	20
3SD1_A	THF links to Rfam database...	0.52	0.45	0.61	19	3885	12	2	10	0	23
4A1C_3	5S_rRNA links to Rfam database...	0.70	0.59	0.84	32	7102	6	0	6	0	22
4A1C_2	5_8S_rRNA links to Rfam database...	0.13	0.15	0.13	5	11741	44	4	31	9	28
4AOB_A	SAM links to Rfam database...	0.59	0.48	0.74	20	4344	8	2	5	1	22
4ENB_A	crcB links to Rfam database...	0.70	0.58	0.85	11	1262	2	1	1	0	8
4ENC_A	crcB links to Rfam database...	0.70	0.58	0.85	11	1313	2	1	1	0	8

Total Scores
MCC	0.483
Average MCC ± 95% Confidence Intervals	0.473 ± 0.263
Sensitivity	0.397
Positive Predictive Value	0.595
Nr of predictions	7

RNA Chain	Rfam family	MCC	SENS	PPV	TP	TN	FP	FP CONTRA	FP INCONS	FP COMP	FN
2LC8_A	GP_knot1 links to Rfam database...	-0.01	0.00	0.00	0	1525	15	2	13	0	20
3SD1_A	THF links to Rfam database...	0.59	0.48	0.74	20	3889	7	1	6	0	22
4A1C_3	5S_rRNA links to Rfam database...	0.69	0.57	0.84	31	7103	6	0	6	0	23
4A1C_2	5_8S_rRNA links to Rfam database...	0.15	0.15	0.15	5	11748	37	3	25	9	28
4AOB_A	SAM links to Rfam database...	0.56	0.40	0.77	17	4349	6	1	4	1	25
4ENB_A	crcB links to Rfam database...	0.69	0.47	1.00	9	1266	0	0	0	0	10
4ENC_A	crcB links to Rfam database...	0.65	0.47	0.90	9	1316	1	1	0	0	10

Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.