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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CentroidAlifold(20) - scored higher in this pairwise comparison

  4. Performance of PETfold_2.0(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for CentroidAlifold(20) & PETfold_2.0(20) [.zip] - may take several seconds...


Overview

Metric CentroidAlifold(20) PETfold_2.0(20)
MCC 0.662 > 0.647
Average MCC ± 95% Confidence Intervals 0.662 ± > 0.647 ±
Sensitivity 0.474 < 0.509
Positive Predictive Value 0.931 > 0.829
Total TP 27 < 29
Total TN 6992 > 6986
Total FP 2 < 6
Total FP CONTRA 0 < 1
Total FP INCONS 2 < 5
Total FP COMP 0 = 0
Total FN 30 > 28
P-value 0.0

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Performance plots


  1. Comparison of performance of CentroidAlifold(20) and PETfold_2.0(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CentroidAlifold(20) and PETfold_2.0(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CentroidAlifold(20) and PETfold_2.0(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CentroidAlifold(20) and PETfold_2.0(20)).

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Performance of CentroidAlifold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for CentroidAlifold(20)

Total Base Pair Counts
Total TP 27
Total TN 6992
Total FP 2
Total FP CONTRA 0
Total FP INCONS 2
Total FP COMP 0
Total FN 30
Total Scores
MCC 0.662
Average MCC ± 95% Confidence Intervals 0.662 ±
Sensitivity 0.474
Positive Predictive Value 0.931
Nr of predictions 1

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2. Individual counts for CentroidAlifold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3V_B 0.66 0.47 0.93 27 6992 2 0 2 0 30

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Performance of PETfold_2.0(20) - scored lower in this pairwise comparison

1. Total counts & total scores for PETfold_2.0(20)

Total Base Pair Counts
Total TP 29
Total TN 6986
Total FP 6
Total FP CONTRA 1
Total FP INCONS 5
Total FP COMP 0
Total FN 28
Total Scores
MCC 0.647
Average MCC ± 95% Confidence Intervals 0.647 ±
Sensitivity 0.509
Positive Predictive Value 0.829
Nr of predictions 1

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2. Individual counts for PETfold_2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3V_B 0.65 0.51 0.83 29 6986 6 1 5 0 28

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.