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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of ContextFold - scored higher in this pairwise comparison

  4. Performance of PETfold_2.0(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for ContextFold & PETfold_2.0(seed) [.zip] - may take several seconds...


Overview

Metric ContextFold PETfold_2.0(seed)
MCC 0.780 > 0.769
Average MCC ± 95% Confidence Intervals 0.786 ± 0.332 > 0.771 ± 0.133
Sensitivity 0.632 < 0.642
Positive Predictive Value 0.968 > 0.924
Total TP 60 < 61
Total TN 11145 > 11141
Total FP 2 < 7
Total FP CONTRA 1 = 1
Total FP INCONS 1 < 4
Total FP COMP 0 < 2
Total FN 35 > 34
P-value 0.0

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Performance plots


  1. Comparison of performance of ContextFold and PETfold_2.0(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for ContextFold and PETfold_2.0(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for ContextFold and PETfold_2.0(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for ContextFold and PETfold_2.0(seed)).

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Performance of ContextFold - scored higher in this pairwise comparison

1. Total counts & total scores for ContextFold

Total Base Pair Counts
Total TP 60
Total TN 11145
Total FP 2
Total FP CONTRA 1
Total FP INCONS 1
Total FP COMP 0
Total FN 35
Total Scores
MCC 0.780
Average MCC ± 95% Confidence Intervals 0.786 ± 0.332
Sensitivity 0.632
Positive Predictive Value 0.968
Nr of predictions 2

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2. Individual counts for ContextFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3V_B 0.76 0.58 1.00 33 6988 0 0 0 0 24
3W1K_J 0.81 0.71 0.93 27 4157 2 1 1 0 11

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Performance of PETfold_2.0(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for PETfold_2.0(seed)

Total Base Pair Counts
Total TP 61
Total TN 11141
Total FP 7
Total FP CONTRA 1
Total FP INCONS 4
Total FP COMP 2
Total FN 34
Total Scores
MCC 0.769
Average MCC ± 95% Confidence Intervals 0.771 ± 0.133
Sensitivity 0.642
Positive Predictive Value 0.924
Nr of predictions 2

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2. Individual counts for PETfold_2.0(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3V_B 0.76 0.61 0.95 35 6984 3 0 2 1 22
3W1K_J 0.78 0.68 0.90 26 4157 4 1 2 1 12

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.