CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Cylofold - scored higher in this pairwise comparison

  4. Performance of RNASampler(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Cylofold & RNASampler(seed) [.zip] - may take several seconds...


Overview

Metric Cylofold RNASampler(seed)
MCC 0.540 > 0.514
Average MCC ± 95% Confidence Intervals 0.558 ± 0.201 > 0.470 ± 0.361
Sensitivity 0.462 > 0.351
Positive Predictive Value 0.637 < 0.759
Total TP 79 > 60
Total TN 24699 < 24744
Total FP 55 > 24
Total FP CONTRA 5 > 2
Total FP INCONS 40 > 17
Total FP COMP 10 > 5
Total FN 92 < 111
P-value 0.0

^top




Performance plots


  1. Comparison of performance of Cylofold and RNASampler(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Cylofold and RNASampler(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Cylofold and RNASampler(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Cylofold and RNASampler(seed)).

^top





Performance of Cylofold - scored higher in this pairwise comparison

1. Total counts & total scores for Cylofold

Total Base Pair Counts
Total TP 79
Total TN 24699
Total FP 55
Total FP CONTRA 5
Total FP INCONS 40
Total FP COMP 10
Total FN 92
Total Scores
MCC 0.540
Average MCC ± 95% Confidence Intervals 0.558 ± 0.201
Sensitivity 0.462
Positive Predictive Value 0.637
Nr of predictions 5

^top



2. Individual counts for Cylofold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.61 0.55 0.69 11 1524 5 0 5 0 9
3O58_3 0.36 0.34 0.38 12 12371 29 5 15 9 23
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.62 0.50 0.78 21 3889 6 0 6 0 21
3W3S_B 0.44 0.38 0.52 15 4724 15 0 14 1 25

^top



Performance of RNASampler(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 60
Total TN 24744
Total FP 24
Total FP CONTRA 2
Total FP INCONS 17
Total FP COMP 5
Total FN 111
Total Scores
MCC 0.514
Average MCC ± 95% Confidence Intervals 0.470 ± 0.361
Sensitivity 0.351
Positive Predictive Value 0.759
Nr of predictions 5

^top



2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1530 10 0 10 0 20
3O58_3 0.45 0.34 0.60 12 12383 12 2 6 4 23
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.60 0.38 0.94 16 3899 1 0 1 0 26
3W3S_B 0.55 0.30 1.00 12 4741 1 0 0 1 28

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.