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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Multilign(seed) - scored higher in this pairwise comparison

  4. Performance of CMfinder(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for Multilign(seed) & CMfinder(20) [.zip] - may take several seconds...


Overview

Metric Multilign(seed) CMfinder(20)
MCC 0.128 > 0.098
Average MCC ± 95% Confidence Intervals 0.128 ± > 0.098 ±
Sensitivity 0.091 > 0.061
Positive Predictive Value 0.188 > 0.167
Total TP 3 > 2
Total TN 7487 < 7491
Total FP 13 > 10
Total FP CONTRA 5 > 1
Total FP INCONS 8 < 9
Total FP COMP 0 = 0
Total FN 30 < 31
P-value 0.0

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Performance plots


  1. Comparison of performance of Multilign(seed) and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(seed) and CMfinder(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(seed) and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(seed) and CMfinder(20)).

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Performance of Multilign(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 3
Total TN 7487
Total FP 13
Total FP CONTRA 5
Total FP INCONS 8
Total FP COMP 0
Total FN 30
Total Scores
MCC 0.128
Average MCC ± 95% Confidence Intervals 0.128 ±
Sensitivity 0.091
Positive Predictive Value 0.188
Nr of predictions 1

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2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3E_8 0.13 0.09 0.19 3 7487 13 5 8 0 30

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Performance of CMfinder(20) - scored lower in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 2
Total TN 7491
Total FP 10
Total FP CONTRA 1
Total FP INCONS 9
Total FP COMP 0
Total FN 31
Total Scores
MCC 0.098
Average MCC ± 95% Confidence Intervals 0.098 ±
Sensitivity 0.061
Positive Predictive Value 0.167
Nr of predictions 1

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3E_8 0.10 0.06 0.17 2 7491 10 1 9 0 31

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.