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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Murlet(seed) - scored higher in this pairwise comparison

  4. Performance of Mastr(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for Murlet(seed) & Mastr(20) [.zip] - may take several seconds...


Overview

Metric Murlet(seed) Mastr(20)
MCC 0.454 > 0.387
Average MCC ± 95% Confidence Intervals 0.455 ± 0.064 > 0.322 ± 0.167
Sensitivity 0.241 > 0.200
Positive Predictive Value 0.861 > 0.754
Total TP 155 > 129
Total TN 116289 < 116298
Total FP 31 < 45
Total FP CONTRA 5 > 3
Total FP INCONS 20 < 39
Total FP COMP 6 > 3
Total FN 489 < 515
P-value 3.13260312532e-08

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Performance plots


  1. Comparison of performance of Murlet(seed) and Mastr(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Murlet(seed) and Mastr(20)).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for Murlet(seed) and Mastr(20)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for Murlet(seed) and Mastr(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Murlet(seed) and Mastr(20)).

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Performance of Murlet(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Murlet(seed)

Total Base Pair Counts
Total TP 155
Total TN 116289
Total FP 31
Total FP CONTRA 5
Total FP INCONS 20
Total FP COMP 6
Total FN 489
Total Scores
MCC 0.454
Average MCC ± 95% Confidence Intervals 0.455 ± 0.064
Sensitivity 0.241
Positive Predictive Value 0.861
Nr of predictions 18

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2. Individual counts for Murlet(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.52 0.27 1.00 3 403 0 0 0 0 8
3GX2_A 0.59 0.35 1.00 14 4357 1 0 0 1 26
3IVN_B 0.53 0.39 0.75 12 2330 4 2 2 0 19
3J3E_8 0.25 0.06 1.00 2 7501 2 0 0 2 31
3J3F_8 0.44 0.19 1.00 7 12239 0 0 0 0 29
3JYX_4 0.23 0.09 0.60 3 12241 4 0 2 2 30
3LA5_A 0.58 0.41 0.82 14 2468 3 1 2 0 20
3NPB_A 0.49 0.28 0.87 13 7006 2 1 1 0 33
3O58_3 0.45 0.20 1.00 7 12396 0 0 0 0 28
3PDR_A 0.44 0.19 1.00 14 12866 0 0 0 0 58
3RKF_A 0.53 0.35 0.80 12 2196 3 1 2 0 22
3SD1_A 0.47 0.26 0.85 11 3903 2 0 2 0 31
3ZEX_C 0.37 0.13 1.00 7 14189 0 0 0 0 45
4A1C_2 0.46 0.21 1.00 7 11774 0 0 0 0 26
4AOB_A 0.58 0.33 1.00 14 4357 1 0 0 1 28
4ENB_A 0.56 0.32 1.00 6 1269 0 0 0 0 13
4ENC_A 0.56 0.32 1.00 6 1320 0 0 0 0 13
4FRG_B 0.15 0.09 0.25 3 3474 9 0 9 0 29

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Performance of Mastr(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(20)

Total Base Pair Counts
Total TP 129
Total TN 116298
Total FP 45
Total FP CONTRA 3
Total FP INCONS 39
Total FP COMP 3
Total FN 515
Total Scores
MCC 0.387
Average MCC ± 95% Confidence Intervals 0.322 ± 0.167
Sensitivity 0.200
Positive Predictive Value 0.754
Nr of predictions 18

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2. Individual counts for Mastr(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.95 0.91 1.00 10 396 0 0 0 0 1
3GX2_A 0.39 0.28 0.55 11 4351 10 0 9 1 29
3IVN_B 0.78 0.65 0.95 20 2325 1 1 0 0 11
3J3E_8 0.00 0.00 0.00 0 7503 0 0 0 0 33
3J3F_8 0.00 0.00 0.00 0 12246 0 0 0 0 36
3JYX_4 0.00 0.00 0.00 0 12246 0 0 0 0 33
3LA5_A 0.76 0.59 1.00 20 2465 0 0 0 0 14
3NPB_A 0.30 0.24 0.39 11 6993 18 1 16 1 35
3O58_3 0.00 0.00 0.00 0 12403 0 0 0 0 35
3PDR_A 0.00 0.00 0.00 0 12880 0 0 0 0 72
3RKF_A 0.70 0.50 1.00 17 2194 0 0 0 0 17
3SD1_A 0.61 0.50 0.75 21 3888 7 1 6 0 21
3ZEX_C 0.00 0.00 0.00 0 14196 0 0 0 0 52
4A1C_2 0.00 0.00 0.00 0 11781 0 0 0 0 33
4AOB_A 0.39 0.26 0.58 11 4352 9 0 8 1 31
4ENB_A 0.39 0.16 1.00 3 1272 0 0 0 0 16
4ENC_A 0.51 0.26 1.00 5 1321 0 0 0 0 14
4FRG_B 0.00 0.00 0.00 0 3486 0 0 0 0 32

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.