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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of Multilign(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & Multilign(seed) [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) Multilign(seed)
MCC 0.443 > 0.401
Average MCC ± 95% Confidence Intervals 0.436 ± 0.663 > 0.377 ± 0.598
Sensitivity 0.323 > 0.283
Positive Predictive Value 0.612 > 0.571
Total TP 41 > 36
Total TN 26003 < 26007
Total FP 32 > 28
Total FP CONTRA 0 < 8
Total FP INCONS 26 > 19
Total FP COMP 6 > 1
Total FN 86 < 91
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and Multilign(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and Multilign(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and Multilign(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and Multilign(seed)).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 41
Total TN 26003
Total FP 32
Total FP CONTRA 0
Total FP INCONS 26
Total FP COMP 6
Total FN 86
Total Scores
MCC 0.443
Average MCC ± 95% Confidence Intervals 0.436 ± 0.663
Sensitivity 0.323
Positive Predictive Value 0.612
Nr of predictions 3

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3E_8 0.32 0.21 0.50 7 7489 11 0 7 4 26
3ZEX_C 0.24 0.17 0.35 9 14170 18 0 17 1 43
4AOB_A 0.74 0.60 0.93 25 4344 3 0 2 1 17

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Performance of Multilign(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 36
Total TN 26007
Total FP 28
Total FP CONTRA 8
Total FP INCONS 19
Total FP COMP 1
Total FN 91
Total Scores
MCC 0.401
Average MCC ± 95% Confidence Intervals 0.377 ± 0.598
Sensitivity 0.283
Positive Predictive Value 0.571
Nr of predictions 3

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2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3E_8 0.13 0.09 0.19 3 7487 13 5 8 0 30
3ZEX_C 0.39 0.27 0.58 14 14172 10 3 7 0 38
4AOB_A 0.61 0.45 0.83 19 4348 5 0 4 1 23

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.