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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of RDfolder - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & RDfolder [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) RDfolder
MCC 0.733 > 0.535
Average MCC ± 95% Confidence Intervals 0.707 ± 0.154 > 0.531 ± 0.221
Sensitivity 0.587 > 0.413
Positive Predictive Value 0.920 > 0.704
Total TP 81 > 57
Total TN 12509 < 12516
Total FP 8 < 26
Total FP CONTRA 0 < 1
Total FP INCONS 7 < 23
Total FP COMP 1 < 2
Total FN 57 < 81
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and RDfolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and RDfolder).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and RDfolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and RDfolder).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 81
Total TN 12509
Total FP 8
Total FP CONTRA 0
Total FP INCONS 7
Total FP COMP 1
Total FN 57
Total Scores
MCC 0.733
Average MCC ± 95% Confidence Intervals 0.707 ± 0.154
Sensitivity 0.587
Positive Predictive Value 0.920
Nr of predictions 5

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.84 0.70 1.00 21 2829 0 0 0 0 9
3J3D_C 0.80 0.68 0.95 19 2755 1 0 1 0 9
4AOB_A 0.74 0.60 0.93 25 4344 3 0 2 1 17
4ENB_A 0.61 0.42 0.89 8 1266 1 0 1 0 11
4ENC_A 0.55 0.42 0.73 8 1315 3 0 3 0 11

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Performance of RDfolder - scored lower in this pairwise comparison

1. Total counts & total scores for RDfolder

Total Base Pair Counts
Total TP 57
Total TN 12516
Total FP 26
Total FP CONTRA 1
Total FP INCONS 23
Total FP COMP 2
Total FN 81
Total Scores
MCC 0.535
Average MCC ± 95% Confidence Intervals 0.531 ± 0.221
Sensitivity 0.413
Positive Predictive Value 0.704
Nr of predictions 5

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2. Individual counts for RDfolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.73 0.57 0.94 17 2832 2 0 1 1 13
3J3D_C 0.72 0.61 0.85 17 2755 3 0 3 0 11
4AOB_A 0.35 0.26 0.48 11 4348 13 1 11 1 31
4ENB_A 0.43 0.32 0.60 6 1265 4 0 4 0 13
4ENC_A 0.43 0.32 0.60 6 1316 4 0 4 0 13

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.