CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

  4. Performance of Alterna - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(seed) & Alterna [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(seed) Alterna
MCC 0.683 > 0.545
Average MCC ± 95% Confidence Intervals 0.643 ± 0.540 > 0.537 ± 0.224
Sensitivity 0.540 > 0.460
Positive Predictive Value 0.870 > 0.656
Total TP 47 > 40
Total TN 7831 > 7824
Total FP 8 < 21
Total FP CONTRA 1 < 3
Total FP INCONS 6 < 18
Total FP COMP 1 > 0
Total FN 40 < 47
P-value 0.0

^top




Performance plots


  1. Comparison of performance of PETfold_pre2.0(seed) and Alterna. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and Alterna).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and Alterna. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and Alterna).

^top





Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(seed)

Total Base Pair Counts
Total TP 47
Total TN 7831
Total FP 8
Total FP CONTRA 1
Total FP INCONS 6
Total FP COMP 1
Total FN 40
Total Scores
MCC 0.683
Average MCC ± 95% Confidence Intervals 0.643 ± 0.540
Sensitivity 0.540
Positive Predictive Value 0.870
Nr of predictions 3

^top



2. Individual counts for PETfold_pre2.0(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.40 0.30 0.55 6 1529 5 0 5 0 14
3J16_L 0.82 0.70 0.95 21 2753 1 0 1 0 9
3UZL_B 0.72 0.54 0.95 20 3549 2 1 0 1 17

^top



Performance of Alterna - scored lower in this pairwise comparison

1. Total counts & total scores for Alterna

Total Base Pair Counts
Total TP 40
Total TN 7824
Total FP 21
Total FP CONTRA 3
Total FP INCONS 18
Total FP COMP 0
Total FN 47
Total Scores
MCC 0.545
Average MCC ± 95% Confidence Intervals 0.537 ± 0.224
Sensitivity 0.460
Positive Predictive Value 0.656
Nr of predictions 3

^top



2. Individual counts for Alterna [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.46 0.40 0.53 8 1525 7 0 7 0 12
3J16_L 0.63 0.53 0.76 16 2754 5 1 4 0 14
3UZL_B 0.52 0.43 0.64 16 3545 9 2 7 0 21

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.