Table of contents:
- Overview
- Performance Plots
- Performance of PETfold_pre2.0(seed)
- scored higher in this pairwise comparison
- Performance of McQFold
- scored lower in this pairwise comparison
- Compile and download dataset for PETfold_pre2.0(seed) & McQFold [.zip] - may take several seconds...
Overview
| Metric |
PETfold_pre2.0(seed) |
|
McQFold |
|---|
| MCC |
0.715 |
>
|
0.484 |
| Average MCC ± 95% Confidence Intervals |
0.699
±
0.059
|
>
|
0.539
±
0.107
|
| Sensitivity |
0.602 |
>
|
0.412 |
| Positive Predictive Value |
0.850 |
>
|
0.571 |
| Total TP |
935 |
>
|
639 |
| Total TN |
1251685 |
>
|
1251666 |
| Total FP |
203 |
<
|
523 |
| Total FP CONTRA |
18 |
<
|
35 |
| Total FP INCONS |
147 |
<
|
445 |
| Total FP COMP |
38 |
<
|
43 |
| Total FN |
617 |
<
|
913 |
| P-value |
5.19332990918e-08 |
Performance plots
-
Comparison of performance of PETfold_pre2.0(seed) and McQFold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data
(individual counts for PETfold_pre2.0(seed)
and McQFold).
-
Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data
(individual counts for PETfold_pre2.0(seed)
and McQFold).
-
Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and McQFold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data
(individual counts for PETfold_pre2.0(seed)
and McQFold).
Performance of PETfold_pre2.0(seed)
- scored higher in this pairwise comparison
1. Total counts & total scores for PETfold_pre2.0(seed)
| Total Base Pair Counts |
|---|
| Total TP |
935 |
| Total TN |
1251685 |
| Total FP |
203 |
| Total FP CONTRA |
18 |
| Total FP INCONS |
147 |
| Total FP COMP |
38 |
| Total FN |
617 |
| Total Scores |
|---|
| MCC |
0.715 |
| Average MCC ± 95% Confidence Intervals |
0.699
±
0.059
|
| Sensitivity |
0.602 |
| Positive Predictive Value |
0.850 |
| Nr of predictions |
26 |
Performance of McQFold
- scored lower in this pairwise comparison
1. Total counts & total scores for McQFold
| Total Base Pair Counts |
|---|
| Total TP |
639 |
| Total TN |
1251666 |
| Total FP |
523 |
| Total FP CONTRA |
35 |
| Total FP INCONS |
445 |
| Total FP COMP |
43 |
| Total FN |
913 |
| Total Scores |
|---|
| MCC |
0.484 |
| Average MCC ± 95% Confidence Intervals |
0.539
±
0.107
|
| Sensitivity |
0.412 |
| Positive Predictive Value |
0.571 |
| Nr of predictions |
26 |
Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based
on the paper by Gardener & Giegerich, 2004.
| 
