Table of contents:
- Overview
- Performance Plots
- Performance of PETfold_pre2.0(seed)
- scored higher in this pairwise comparison
- Performance of Multilign(20)
- scored lower in this pairwise comparison
- Compile and download dataset for PETfold_pre2.0(seed) & Multilign(20) [.zip] - may take several seconds...
Overview
| Metric |
PETfold_pre2.0(seed) |
|
Multilign(20) |
|---|
| MCC |
0.731 |
>
|
0.514 |
| Average MCC ± 95% Confidence Intervals |
0.702
±
0.085
|
>
|
0.503
±
0.141
|
| Sensitivity |
0.616 |
>
|
0.433 |
| Positive Predictive Value |
0.870 |
>
|
0.617 |
| Total TP |
356 |
>
|
250 |
| Total TN |
89569 |
<
|
89573 |
| Total FP |
75 |
<
|
177 |
| Total FP CONTRA |
3 |
<
|
17 |
| Total FP INCONS |
50 |
<
|
138 |
| Total FP COMP |
22 |
=
|
22 |
| Total FN |
222 |
<
|
328 |
| P-value |
2.86595104665e-08 |
Performance plots
-
Comparison of performance of PETfold_pre2.0(seed) and Multilign(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data
(individual counts for PETfold_pre2.0(seed)
and Multilign(20)).
-
Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data
(individual counts for PETfold_pre2.0(seed)
and Multilign(20)).
-
Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and Multilign(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data
(individual counts for PETfold_pre2.0(seed)
and Multilign(20)).
Performance of PETfold_pre2.0(seed)
- scored higher in this pairwise comparison
1. Total counts & total scores for PETfold_pre2.0(seed)
| Total Base Pair Counts |
|---|
| Total TP |
356 |
| Total TN |
89569 |
| Total FP |
75 |
| Total FP CONTRA |
3 |
| Total FP INCONS |
50 |
| Total FP COMP |
22 |
| Total FN |
222 |
| Total Scores |
|---|
| MCC |
0.731 |
| Average MCC ± 95% Confidence Intervals |
0.702
±
0.085
|
| Sensitivity |
0.616 |
| Positive Predictive Value |
0.870 |
| Nr of predictions |
16 |
Performance of Multilign(20)
- scored lower in this pairwise comparison
1. Total counts & total scores for Multilign(20)
| Total Base Pair Counts |
|---|
| Total TP |
250 |
| Total TN |
89573 |
| Total FP |
177 |
| Total FP CONTRA |
17 |
| Total FP INCONS |
138 |
| Total FP COMP |
22 |
| Total FN |
328 |
| Total Scores |
|---|
| MCC |
0.514 |
| Average MCC ± 95% Confidence Intervals |
0.503
±
0.141
|
| Sensitivity |
0.433 |
| Positive Predictive Value |
0.617 |
| Nr of predictions |
16 |
Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based
on the paper by Gardener & Giegerich, 2004.
| 
