CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(seed) - scored higher in this pairwise comparison

  4. Performance of PPfold(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(seed) & PPfold(20) [.zip] - may take several seconds...


Overview

Metric RNASampler(seed) PPfold(20)
MCC 0.423 > 0.419
Average MCC ± 95% Confidence Intervals 0.424 ± 0.241 > 0.402 ± 0.255
Sensitivity 0.300 = 0.300
Positive Predictive Value 0.600 > 0.590
Total TP 69 = 69
Total TN 51738 > 51736
Total FP 71 > 63
Total FP CONTRA 4 > 0
Total FP INCONS 42 < 48
Total FP COMP 25 > 15
Total FN 161 = 161
P-value 0.0

^top




Performance plots


  1. Comparison of performance of RNASampler(seed) and PPfold(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(seed) and PPfold(20)).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for RNASampler(seed) and PPfold(20)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(seed) and PPfold(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(seed) and PPfold(20)).

^top





Performance of RNASampler(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 69
Total TN 51738
Total FP 71
Total FP CONTRA 4
Total FP INCONS 42
Total FP COMP 25
Total FN 161
Total Scores
MCC 0.423
Average MCC ± 95% Confidence Intervals 0.424 ± 0.241
Sensitivity 0.300
Positive Predictive Value 0.600
Nr of predictions 6

^top



2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3E_8 0.12 0.09 0.17 3 7485 22 2 13 7 30
3J3F_8 0.44 0.33 0.57 12 12225 15 1 8 6 24
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.60 0.38 0.94 16 3899 1 0 1 0 26
3ZEX_C 0.32 0.19 0.53 10 14177 13 1 8 4 42
4A1C_2 0.31 0.24 0.40 8 11761 20 0 12 8 25

^top



Performance of PPfold(20) - scored lower in this pairwise comparison

1. Total counts & total scores for PPfold(20)

Total Base Pair Counts
Total TP 69
Total TN 51736
Total FP 63
Total FP CONTRA 0
Total FP INCONS 48
Total FP COMP 15
Total FN 161
Total Scores
MCC 0.419
Average MCC ± 95% Confidence Intervals 0.402 ± 0.255
Sensitivity 0.300
Positive Predictive Value 0.590
Nr of predictions 6

^top



2. Individual counts for PPfold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3E_8 0.14 0.09 0.23 3 7490 13 0 10 3 30
3J3F_8 0.33 0.25 0.43 9 12225 18 0 12 6 27
3RKF_A 0.73 0.56 0.95 19 2191 1 0 1 0 15
3SD1_A 0.68 0.52 0.88 22 3891 3 0 3 0 20
3ZEX_C 0.33 0.21 0.52 11 14175 12 0 10 2 41
4A1C_2 0.21 0.15 0.29 5 11764 16 0 12 4 28

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.