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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNAalifold(seed) - scored higher in this pairwise comparison

  4. Performance of CMfinder(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNAalifold(seed) & CMfinder(20) [.zip] - may take several seconds...


Overview

Metric RNAalifold(seed) CMfinder(20)
MCC 0.507 > 0.333
Average MCC ± 95% Confidence Intervals 0.409 ± 0.924 > 0.337 ± 0.514
Sensitivity 0.257 > 0.208
Positive Predictive Value 1.000 > 0.538
Total TP 26 > 21
Total TN 23209 > 23196
Total FP 0 < 18
Total FP CONTRA 0 < 2
Total FP INCONS 0 < 16
Total FP COMP 0 = 0
Total FN 75 < 80
P-value 0.0

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Performance plots


  1. Comparison of performance of RNAalifold(seed) and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNAalifold(seed) and CMfinder(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNAalifold(seed) and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNAalifold(seed) and CMfinder(20)).

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Performance of RNAalifold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNAalifold(seed)

Total Base Pair Counts
Total TP 26
Total TN 23209
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 75
Total Scores
MCC 0.507
Average MCC ± 95% Confidence Intervals 0.409 ± 0.924
Sensitivity 0.257
Positive Predictive Value 1.000
Nr of predictions 3

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2. Individual counts for RNAalifold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3E_8 0.00 0.00 0.00 0 7503 0 0 0 0 33
3J3F_8 0.50 0.25 1.00 9 12237 0 0 0 0 27
4FRG_B 0.73 0.53 1.00 17 3469 0 0 0 0 15

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Performance of CMfinder(20) - scored lower in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 21
Total TN 23196
Total FP 18
Total FP CONTRA 2
Total FP INCONS 16
Total FP COMP 0
Total FN 80
Total Scores
MCC 0.333
Average MCC ± 95% Confidence Intervals 0.337 ± 0.514
Sensitivity 0.208
Positive Predictive Value 0.538
Nr of predictions 3

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3E_8 0.10 0.06 0.17 2 7491 10 1 9 0 31
3J3F_8 0.45 0.33 0.60 12 12226 8 1 7 0 24
4FRG_B 0.47 0.22 1.00 7 3479 0 0 0 0 25

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.