CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(20) - scored higher in this pairwise comparison

  4. Performance of Alterna - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(20) & Alterna [.zip] - may take several seconds...


Overview

Metric TurboFold(20) Alterna
MCC 0.676 > 0.584
Average MCC ± 95% Confidence Intervals 0.686 ± 0.219 > 0.597 ± 0.298
Sensitivity 0.544 > 0.495
Positive Predictive Value 0.848 > 0.699
Total TP 56 > 51
Total TN 9064 > 9057
Total FP 12 < 24
Total FP CONTRA 1 < 2
Total FP INCONS 9 < 20
Total FP COMP 2 = 2
Total FN 47 < 52
P-value 0.0

^top




Performance plots


  1. Comparison of performance of TurboFold(20) and Alterna. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and Alterna).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and Alterna. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and Alterna).

^top





Performance of TurboFold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(20)

Total Base Pair Counts
Total TP 56
Total TN 9064
Total FP 12
Total FP CONTRA 1
Total FP INCONS 9
Total FP COMP 2
Total FN 47
Total Scores
MCC 0.676
Average MCC ± 95% Confidence Intervals 0.686 ± 0.219
Sensitivity 0.544
Positive Predictive Value 0.848
Nr of predictions 3

^top



2. Individual counts for TurboFold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3AMU_B 0.70 0.59 0.84 16 2984 5 0 3 2 11
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.59 0.48 0.74 20 3889 7 1 6 0 22

^top



Performance of Alterna - scored lower in this pairwise comparison

1. Total counts & total scores for Alterna

Total Base Pair Counts
Total TP 51
Total TN 9057
Total FP 24
Total FP CONTRA 2
Total FP INCONS 20
Total FP COMP 2
Total FN 52
Total Scores
MCC 0.584
Average MCC ± 95% Confidence Intervals 0.597 ± 0.298
Sensitivity 0.495
Positive Predictive Value 0.699
Nr of predictions 3

^top



2. Individual counts for Alterna [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3AMU_B 0.64 0.59 0.70 16 2980 9 0 7 2 11
3RKF_A 0.69 0.56 0.86 19 2189 3 1 2 0 15
3SD1_A 0.46 0.38 0.57 16 3888 12 1 11 0 26

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.