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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(20) - scored higher in this pairwise comparison

  4. Performance of Mastr(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(20) & Mastr(seed) [.zip] - may take several seconds...


Overview

Metric TurboFold(20) Mastr(seed)
MCC 0.616 > 0.000
Average MCC ± 95% Confidence Intervals 0.618 ± 0.099 > 0.000 ± 0.000
Sensitivity 0.508 > 0.000
Positive Predictive Value 0.752 > 0.000
Total TP 372 > 0
Total TN 112809 < 113304
Total FP 168 > 0
Total FP CONTRA 11 > 0
Total FP INCONS 112 > 0
Total FP COMP 45 > 0
Total FN 361 < 733
P-value 5.10776592382e-08

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Performance plots


  1. Comparison of performance of TurboFold(20) and Mastr(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and Mastr(seed)).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for TurboFold(20) and Mastr(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and Mastr(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and Mastr(seed)).

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Performance of TurboFold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(20)

Total Base Pair Counts
Total TP 372
Total TN 112809
Total FP 168
Total FP CONTRA 11
Total FP INCONS 112
Total FP COMP 45
Total FN 361
Total Scores
MCC 0.616
Average MCC ± 95% Confidence Intervals 0.618 ± 0.099
Sensitivity 0.508
Positive Predictive Value 0.752
Nr of predictions 20

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2. Individual counts for TurboFold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3AMU_B 0.70 0.59 0.84 16 2984 5 0 3 2 11
3J20_0 0.66 0.57 0.77 17 2828 6 0 5 1 13
3J20_1 0.96 0.91 1.00 21 2905 0 0 0 0 2
3J2L_3 0.74 0.58 0.94 31 7842 5 0 2 3 22
3J3D_C 0.82 0.71 0.95 20 2754 1 0 1 0 8
3J3E_7 0.65 0.54 0.78 29 7103 8 1 7 0 25
3J3E_8 0.17 0.15 0.21 5 7479 28 2 17 9 28
3J3F_7 0.79 0.68 0.92 34 7223 4 0 3 1 16
3J3F_8 0.38 0.36 0.39 13 12213 34 2 18 14 23
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.59 0.48 0.74 20 3889 7 1 6 0 22
3ZEX_D 0.76 0.63 0.91 31 6987 3 0 3 0 18
3ZEX_C 0.39 0.27 0.56 14 14171 14 2 9 3 38
3ZND_W 0.43 0.39 0.47 9 2984 12 1 9 2 14
4A1C_3 0.69 0.57 0.84 31 7103 6 0 6 0 23
4A1C_2 0.18 0.15 0.21 5 11757 28 0 19 9 28
4AOB_A 0.56 0.40 0.77 17 4349 6 1 4 1 25
4ENB_A 0.69 0.47 1.00 9 1266 0 0 0 0 10
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10
4FRG_B 0.81 0.66 1.00 21 3465 0 0 0 0 11

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Performance of Mastr(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(seed)

Total Base Pair Counts
Total TP 0
Total TN 113304
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 733
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ± 0.000
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 20

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2. Individual counts for Mastr(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3AMU_B 0.00 0.00 0.00 0 3003 0 0 0 0 27
3J20_0 0.00 0.00 0.00 0 2850 0 0 0 0 30
3J20_1 0.00 0.00 0.00 0 2926 0 0 0 0 23
3J2L_3 0.00 0.00 0.00 0 7875 0 0 0 0 53
3J3D_C 0.00 0.00 0.00 0 2775 0 0 0 0 28
3J3E_7 0.00 0.00 0.00 0 7140 0 0 0 0 54
3J3E_8 0.00 0.00 0.00 0 7503 0 0 0 0 33
3J3F_7 0.00 0.00 0.00 0 7260 0 0 0 0 50
3J3F_8 0.00 0.00 0.00 0 12246 0 0 0 0 36
3RKF_A 0.00 0.00 0.00 0 2211 0 0 0 0 34
3SD1_A 0.00 0.00 0.00 0 3916 0 0 0 0 42
3ZEX_D 0.00 0.00 0.00 0 7021 0 0 0 0 49
3ZEX_C 0.00 0.00 0.00 0 14196 0 0 0 0 52
3ZND_W 0.00 0.00 0.00 0 3003 0 0 0 0 23
4A1C_3 0.00 0.00 0.00 0 7140 0 0 0 0 54
4A1C_2 0.00 0.00 0.00 0 11781 0 0 0 0 33
4AOB_A 0.00 0.00 0.00 0 4371 0 0 0 0 42
4ENB_A 0.00 0.00 0.00 0 1275 0 0 0 0 19
4ENC_A 0.00 0.00 0.00 0 1326 0 0 0 0 19
4FRG_B 0.00 0.00 0.00 0 3486 0 0 0 0 32

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.