ModeRNA

A program for comparative RNA modeling

by Magdalena Rother, Kristian Rother, Tomasz Puton, Janusz Bujnicki

http://iimcb.genesilico.pl/moderna/

What is ModeRNA

ModeRNA is a program for comparative modeling of RNA 3D structures. It requires a pairwise sequence alignment and a structural template to generate a 3D structural model of the target RNA sequence via either a fully automated or script-based approaches. ModeRNA is capable of handling 115 different nucleotide modifications and bridging gaps using fragments derived from an extensive fragment library.

ModeRNA can also be integrated into other programs. If you wish to learn the basic manipulation of ModeRNA through a tutorial, we recommend that you read the Tutorial and/or the Frequently Asked Questions.

News:

2010/07/21 - ModeRNA 1.5 released with secondary structure modeling functions (see RELEASE NOTES).

2010/02/13 - ModeRNA 1.4 released with easier installation & cleanup feature.

2010/02/13 - ModeRNA 1.3 released with improved linker/backbone modeling.

2009/11/23 - ModeRNA 1.2 released with changed order of sequences in the alignment.

2009/09/21 - ModeRNA 1.1 released with many improvements and bugfixes.