| Name | Acute Myeloid Leukemia (xX:Xm) |
| Description | Decrease in 2'-O-Me due to knock-out of SNORD42A leads to a decrease in ribosomal proteins translation. 2'-O-Me impacts global protein translation by fine-tuning the synthesis of the translational machinery. |
| Related RNA reaction | xX:Xm |
| Found in RNA | rRNA |
| Modified Transcript | rRNA 18S ( position U116) |
| Mapping Technology | RiboMeth-Seq |
| Quantification techniques | qPCR |
| Acronym | Full name | Enzyme Role | Organism |
|---|
| ID | Title | Authors | Journal | Details | ||
|---|---|---|---|---|---|---|
| 962 | Site-specific methylation of 18S ribosomal RNA by SNORD42A is required for acutemyeloid leukemia cell proliferation. | Pauli C | Blood | [details] | 32097467 | S0006-4971(20)61978-4 |