Acute Myeloid Leukemia (xX:Xm) - disease summary
Acute Myeloid Leukemia (xX:Xm)
Decrease in 2'-O-Me due to knock-out of SNORD42A leads to a decrease in ribosomal proteins translation. 2'-O-Me impacts global protein translation by fine-tuning the synthesis of the translational machinery.
Related RNA reaction
Found in RNA
rRNA 18S ( position U116)
Enzymes connected to this disease:
Site-specific methylation of 18S ribosomal RNA by SNORD42A is required for acutemyeloid leukemia cell proliferation.
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