|Acute Myeloid Leukemia (N:Nm)
|Decrease in 2'-O-Me due to knock-out of SNORD42A leads to a decrease in ribosomal proteins translation. 2'-O-Me impacts global protein translation by fine-tuning the synthesis of the translational machinery.
|Related RNA reaction
|Found in RNA
|rRNA 18S ( position U116)
|Site-specific methylation of 18S ribosomal RNA by SNORD42A is required for acutemyeloid leukemia cell proliferation.