Modomics - A Database of RNA Modifications

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Title	PubMed ID / DOI
"NAD-capQ" detection and quantitation of NAD caps.	30045887
1 METTL8 is required for 3-methylcytosine modification in human mitochondrial tRNAs	https://www.biorxiv.org/content/10.1101/2021.05.02
1,4,9-Triazaspiro[5.5]undecan-2-one Derivatives as Potent and Selective METTL3 Inhibitors.	34431664
1.92 Angstrom Zinc-Free APOBEC3F Catalytic Domain Crystal Structure.	27139641
1.92 Angstrom Zinc-Free APOBEC3F Catalytic Domain Crystal Structure.	27139641
15N-labeled tRNA. Identification of 4-thiouridine in Escherichia coli tRNASer1 and tRNATyr2 by 1H-15N two-dimensional NMR spectroscopy.	3638307
16S ribosomal RNA pseudouridine synthase RsuA of Escherichia coli: deletion, mutation of the conserved Asp102 residue, and sequence comparison among all other pseudouridine synthases.	10376875
2'-O-Methyl-5-hydroxymethylcytidine: A Second Oxidative Derivative of 5-Methylcytidine in RNA.	28107630
2'-O-methylation of the mRNA cap protects RNAs from decapping and degradation by DXO	29601584
2'-O-ribose methylation of cap2 in human: function and evolution in a horizontally mobile family.	21310715
2′-O-Methyl Thiomethyl Modifications in Hammerhead Ribozymes	10.1080/07328319708006114
3-(3-amino-3-carboxypropyl)-5,6-Dihydrouridine is one of two novel post-transcriptional modifications in tRNA(Lys) (UUU) from Trypanosoma brucei.	22040320
4-Demethylwyosine synthase from Pyrococcus abyssi is a radical-S-adenosyl-L-methionine enzyme with an additional [4Fe-4S](+2) cluster that interacts with the pyruvate co-substrate.	23043105
5' End Nicotinamide Adenine Dinucleotide Cap in Human Cells Promotes RNA Decay through DXO-Mediated deNADding.	28283058
5-methoxyuridine: a new minor constituent located in the first position of the anticodon of tRNAAla, tRNAThr, and tRNAVal from Bacillus subtilis.	825836
5-methylcytosine in RNA: detection, enzymatic formation and biological functions.	20007150
5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs	31358969
7-Methylguanosine diphosphate (m(7)GDP) is not hydrolyzed but strongly bound by decapping scavenger (dcpS) enzymes and potently inhibits their activity.	22985415
90 S pre-ribosome transformation into the primordial 40 S subunit.	32943521
[Knockdown of YTH N(6)-methyladenosine RNA binding protein 2 (YTHDF2) inhibitsproliferation and promotes apoptosis in MGC-803 gastric cancer cells].	29382422
A bimodular nuclear localization signal assembled via an extended double-stranded RNA-binding domain acts as an RNA-sensing signal for transportin 1.	24753571
A Bump-Hole Approach for Directed RNA Editing.	30581135
A capping-independent function of MePCE in stabilizing 7SK snRNA and facilitating the assembly of 7SK snRNP.	19906723
A catalytic intermediate and several flavin redox states stabilized by folate-dependent tRNA methyltransferase from Bacillus subtilis.	21561081
A chemical screen for biological small molecule-RNA conjugates reveals CoA-linked RNA.	19416889
A cluster of methylations in the domain IV of 25S rRNA is required for ribosome stability.	25125595
A common variant in the FTO gene is associated with body mass index and predisposesto childhood and adult obesity.	17434869
A commonly carried allele of the obesity-related FTO gene is associated with reducedbrain volume in the healthy elderly.	20404173
A Complement to the Modern Crystallographer'S Toolbox: Caged Gadolinium Complexes with Versatile Binding Modes.	24914962
A complete landscape of post-transcriptional modifications in mammalian mitochondrial tRNAs.	24831542
A conserved family of Saccharomyces cerevisiae synthases effects dihydrouridine modification of tRNA.	12003496
A conserved modified wobble nucleoside (mcm5s2U) in lysyl-tRNA is required for viability in yeast.	17592039
A cyclic form of N(6)-threonylcarbamoyladenosine as a widely distributed tRNA hypermodification.	23242255
A cytidine deaminase edits C to U in transfer RNAs in Archaea	19407206
A cytidine deaminase edits C to U in transfer RNAs in Archaea.	19407206
A disease-causing point mutation in human mitochondrial tRNAMet rsults in tRNA misfolding leading to defects in translational initiation and elongation.	18835817
A disrupted RNA editing balance mediated by ADARs (Adenosine DeAminases that act on RNA) in human hepatocellular carcinoma.	23766440
A distinct assembly pathway of the human 39S late pre-mitoribosome	34315873
A domain of the actin binding protein Abp140 is the yeast methyltransferase responsible for 3-methylcytidine modification in the tRNA anti-codon loop.	21518804
A dual role of human tRNA methyltransferase hTrmt13 in regulating translation and transcription	34850409
A dual-specificity pseudouridine synthase: an Escherichia coli synthase purified and cloned on the basis of its specificity for psi 746 in 23S RNA is also specific for psi 32 in tRNA(phe).	7493321
A Facile Synthesis of the Phosphoramidites of 2-N-Methyl-2′- deoxy (or 2′-O-allyl)-ψ-isocytidine, 1, 3-Dimethyl-2′-deoxy-ψ-uridine and N1- Methyl-2′-O-allyl-ψ-uridine as Synthons Suitable for Oligonuc	10.1080/15257779408009476
A fluorescence assay for phenylalanine transfer RNA.	5722700
A functional proteomics approach links the ubiquitin-related modifier Urm1 to a tRNA modification pathway.	19017811
A gain of function mutation in a protein mediates production of novel modified nucleosides.	15861125
A Genome-wide CRISPR Death Screen Identifies Genes Essential for Oxidative Phosphorylation.	27667664
A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae.	18755837
A genome-wide screen identifies the evolutionarily conserved KEOPS complex as a telomere regulator.	16564010
A High-Throughput Radioactivity-Based Assay for Screening SARS-CoV-2 nsp10-nsp16 Complex.	33874769
A homozygous truncating mutation in PUS3 expands the role of tRNA modification in normal cognition.	27055666
A human mitochondrial GTP binding protein related to tRNA modification may modulate phenotypic expression of the deafness-associated mitochondrial 12S rRNA mutation.	12370316
A human mitochondrial transcription factor is related to RNA adenine methyltransferases and binds S-adenosylmethionine.	11809803
A Left-Handed RNA Double Helix Bound by the Zalpha Domain of the RNA-Editing Enzyme ADAR1.	17437712
A limited number of pseudouridine residues in the human atac spliceosomal UsnRNAs as compared to human major spliceosomal UsnRNAs	10580478
A map of 5-methylcytosine residues in Trypanosoma brucei tRNA revealed by sodium bisulfite sequencing.	24389163
A METTL3-METTL14 complex mediates mammalian nuclear RNA N-adenosine methylation.	24316715
A minimalist glutamyl-tRNA synthetase dedicated to aminoacylation of the tRNAAsp QUC anticodon.	15150343
A mitochondrial rRNA dimethyladenosine methyltransferase in Arabidopsis.	19929881
A new function of S-adenosylmethionine: the ribosyl moiety of AdoMet is the precursor of the cyclopentenediol moiety of the tRNA wobble base queuine.	8347586
A new mechanism for chloramphenicol, florfenicol and clindamycin resistance: methylation of 23S ribosomal RNA at A2503.	16091044
A new RNA synthetic method with a 2'-O-(2-cyanoethoxymethyl) protecting group.	16048321
A novel cloverleaf structure found in mammalian mitochondrial tRNA(Ser) (UCN).	1840673
A novel human tRNA-dihydrouridine synthase involved in pulmonary carcinogenesis.	15994936
A novel link between the biosynthesis of aromatic amino acids and transfer RNA modification in Escherichia coli.	6160251
A novel methyltransferase required for the formation of the hypermodified nucleoside wybutosine in eucaryotic tRNA.	16005430
A novel minimum ribozyme with oxidoreduction activity.	2271669
A novel Nop5-sRNA interaction that is required for efficient archaeal box C/D sRNP formation.	20962039
A Novel RNA Editing Sensor Tool and a Specific Agonist Determine Neuronal Protein Expression of RNA-Edited Glycine Receptors and Identify a Genomic APOBEC1 Dimorphism as a New Genetic Risk Factor of Epilepsy.	29375302
A novel translational repressor mRNA is edited extensively in livers containingtumors caused by the transgene expression of the apoB mRNA-editing enzyme.	9030685
A novel unanticipated type of pseudouridine synthase with homologs in bacteria, archaea, and eukarya.	12756329
A paradigm for biological sulfur transfers via persulfide groups: a persulfide-disulfide-thiol cycle in 4-thiouridine biosynthesis.	12510310
A paradigm for local conformational control of function in the ribosome: binding of ribosomal protein S19 to Escherichia coli 16S rRNA in the presence of S7 is required for methylation of m2G966 and blocks methylation of m5C967 by their respective methyltransferases.	1766869
A previously unidentified activity of yeast and mouse RNA:pseudouridine synthases 1 (Pus1p) on tRNAs.	16804160
A primordial RNA modification enzyme: the case of tRNA (m1A) methyltransferase.	14739239
A primordial tRNA modification required for the evolution of life?	11226173
A pseudouridine synthase module is essential for mitochondrial protein synthesis and cell viability.	27974379
A purified selenophosphate-dependent enzyme from Salmonella typhimurium catalyzes the replacement of sulfur in 2-thiouridine residues in tRNAs with selenium.	7520175
A role for the universal Kae1/Qri7/YgjD (COG0533) family in tRNA modification.	21285948
A second function for pseudouridine synthases: A point mutant of RluD unable to form pseudouridines 1911, 1915, and 1917 in Escherichia coli 23S ribosomal RNA restores normal growth to an RluD-minus strain.	11453071
A second type of N7-guanine RNA cap methyltransferase in an unusual locus of a large RNA virus genome.	36265859
A single acetylation of 18S rRNA is essential for biogenesis of the small ribosomal subunit in Saccharomyces cerevisiae.	25086048
A single methyltransferase YefA (RlmCD) catalyses both m5U747 and m5U1939 modifications in Bacillus subtilis 23S rRNA.	21824914
A single zinc ion is sufficient for an active Trypanosoma brucei tRNA editing deaminase.	21507956
A small RNA derived from RNA coactivator SRA blocks steroid receptor signaling via inhibition of Pus1p-mediated pseudouridylation of SRA: evidence of a novel RNA binding domain in the N-terminus of steroid receptors.	22998747
A specific modification next to the anticodon of phenylalanine transfer ribonucleic acid.	5698615
A splice site mutation in the methyltransferase gene FTSJ1 in Xp11.23 is associated with non-syndromic mental retardation in a large Belgian family (MRX9).	15342698
A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor ofN6-methyladenosine demethylase FTO.	28553460
A structural, phylogenetic, and functional study of 15.5-kD/Snu13 protein binding on U3 small nucleolar RNA.	12810916
A subcomplex of human mitochondrial RNase P is a bifunctional methyltransferase--extensive moonlighting in mitochondrial tRNA biogenesis.	23042678
A third member of the RNA-specific adenosine deaminase gene family, ADAR3, contains both single- and double-stranded RNA binding domains.	10836796
A tRNA methyltransferase paralog is important for ribosome stability and cell division in Trypanosoma brucei.	26888608
A truncated aminoacyl-tRNA synthetase modifies RNA.	15096612
A U3 snoRNP protein with homology to splicing factor PRP4 and G beta domains is required for ribosomal RNA processing.	8508778
A Unique RNA Fold in the Ruma-RNA-Cofactor Ternary Complex Contributes to Substrate Selectivity and Enzymatic Function	15766524
A unique RNA Fold in the RumA-RNA-cofactor ternary complex contributes to substrate selectivity and enzymatic function.	15766524
A vastly increased chemical variety of RNA modifications that includes a thioacetal structure	29624844
A-to-I and C-to-U editing within transfer RNAs.	22022967
A-to-I RNA editing of BLCAP lost the inhibition to STAT3 activation in cervicalcancer.	28455960
ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.	15087549
Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders.	25063673
Aberrant RNA homeostasis in amyotrophic lateral sclerosis: potential for newtherapeutic targets?	25531686
Abnormality of m6A mRNA Methylation Is Involved in Alzheimer's Disease.	32184705
Absolute and relative quantification of RNA modifications via biosynthetic isotopomers.	25129236
Acquisition of a bacterial RumA-type tRNA(uracil-54, C5)-methyltransferase by Archaea through an ancient horizontal gene transfer.	18069966
Acquisition of the wobble modification in mitochondrial tRNALeu(CUN) bearing the G12300A mutation suppresses the MELAS molecular defect.	16446307
Actin-binding protein ABP140 is a methyltransferase for 3-methylcytidine at position 32 of tRNAs in Saccharomyces cerevisiae.	21518805
Active site in RrmJ, a heat shock-induced methyltransferase.	12181314
Active site mapping and substrate specificity of bacterial Hen1, a manganese-dependent 3' terminal RNA ribose 2'O-methyltransferase.	21205839
Active Site of Lysyl-tRNA Synthetase: Structural Studies of the Adenylation Reaction	10913247
Acute spinal cord injury persistently reduces R/G RNA editing of AMPA receptors.	20456005
ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia.	23275297
ADAR2 functions as a tumor suppressor via editing IGFBP7 in esophageal squamous cell carcinoma.	28035363
Adenosine-to-inosine RNA editing mediated by ADARs in esophageal squamous cell carcinoma.	24302582
Agmatidine, a modified cytidine in the anticodon of archaeal tRNA(Ile), base pairs with adenosine but not with guanosine.	20133752
Agmatine-conjugated cytidine in a tRNA anticodon is essential for AUA decoding in archaea.	20139989
AI-empowered integrative structural characterization of m 6 A methyltransferase complex.	36357785
AID Recognizes Structured DNA for Class Switch Recombination.	28757211
AID Recognizes Structured DNA for Class Switch Recombination.	28757211
Alanine-scanning mutagenesis of the predicted rRNA-binding domain of ErmC' redefines the substrate-binding site and suggests a model for protein-RNA interactions.	12907737
ALKBH1 is an RNA dioxygenase responsible for cytoplasmic and mitochondrial tRNA modifications.	28472312
ALKBH5 Inhibits Pancreatic Cancer Motility by Decreasing Long Non-Coding RNA KCNK15-AS1 Methylation.	30032148
ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility.	23177736
ALKBH5 promotes invasion and metastasis of gastric cancer by decreasing methylation of the lncRNA NEAT1.	31290116
ALKBH5-m(6)A-FOXM1 signaling axis promotes proliferation and invasion of lungadenocarcinoma cells under intermittent hypoxia.	31677788
ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNA.	21285950
Altered adenosine-to-inosine RNA editing in human cancer	17908822
Altered editing in cyclic nucleotide phosphodiesterase 8A1 gene transcripts of systemic lupus erythematosus T lymphocytes	18462347
Altered Editing of Serotonin 2C Receptor Pre-mRNA in the Prefrontal Cortex of Depressed Suicide Victims	11988167
Alternate rRNA secondary structures as regulators of translation	21217697
Alternative conformations of the archaeal Nop56/58-fibrillarin complex imply flexibility in box C/D RNPs.	17617422
Alternative Conformations of the Archaeal Nop56/58-Fibrillarin Complex Imply Flexibility in Box C/D RNPs.	17617422
Alternative splicing and extensive RNA editing of human TPH2 transcripts.	20126463
Alternative Tertiary Structure of tRNA for Recognition by a Posttranscriptional Modification Enzyme	12732145
Alternative tertiary structure of tRNA for recognition by a posttranscriptional modification enzyme.	12732145
Alu-dependent RNA editing of GLI1 promotes malignant regeneration in multiple myeloma.	29203771
Aminoacylation of the anticodon stem by a tRNA-synthetase paralog: relic of an ancient code?	15450604
AML1-ETO requires enhanced C/D box snoRNA/RNP formation to induce self-renewal and leukaemia.	28650479
AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders	31300657
An adenosine deaminase that generates inosine at the wobble position of tRNAs.	10550050
An adenosine-to-inosine tRNA-editing enzyme that can perform C-to-U deamination of DNA.	17483465
An aminoacyl-tRNA synthetase-like protein encoded by the Escherichia coli yadB gene glutamylates specifically tRNAAsp.	15096594
An archaeal orthologue of the universal protein Kae1 is an iron metalloprotein which exhibits atypical DNA-binding properties and apurinic-endonuclease activity in vitro.	17766251
An arginine-aspartate network in the active site of bacterial TruB is critical for catalyzing pseudouridine formation.	24371284
An association study of the m6A genes with major depressive disorder in Chinese Hanpopulation.	26047305
An ATP-binding cassette transporter and two rRNA methyltransferases are involved in resistance to avilamycin in the producer organism Streptomyces viridochromogenes Tu57.	11181344
An early step in wobble uridine tRNA modification requires the Elongator complex.	15769872
An essential function of Saccharomyces cerevisiae RNA triphosphatase Cet1 is to stabilize RNA guanylyltransferase Ceg1 against thermal inactivation.	11463793
An essential yeast protein, CBF5p, binds in vitro to centromeres and microtubules.	8336724
An extended dsRBD is required for post-transcriptional modification in human tRNAs.	26429968
An extended dsRBD is required for post-transcriptional modification in human tRNAs.	26429968
An extended structure of the APOBEC3G catalytic domain suggests a unique holoenzyme model	19389408
An extensive allelic series of Drosophila kae1 mutants reveals diverse and tissue-specific requirements for t6A biogenesis	26516084
An Improved Synthesis of Inosine 3′-Phosphoramidite	10.1080/00397910008086956
An intact Box C sequence in the U3 snRNA is required for binding of fibrillarin, the protein common to the major family of nucleolar snRNPs.	1714385
An RNA modification enzyme directly senses reactive oxygen species for translational regulation in Enterococcus faecalis	37433804
An RNA-modifying enzyme that governs both the codon and amino acid specificities of isoleucine tRNA.	14527414
Analysis of deletion phenotypes and GFP fusions of 21 novel Saccharomyces cerevisiae open reading frames.	10649453
Analysis of GTP addition in the reverse (3'-5') direction by human tRNA His guanylyltransferase.	33758037
Analysis of pre-mRNA and pre-rRNA processing factor Snu13p structure and mutants.	17631273
Analysis of sequence and structural features that identify the B/C motif of U3 small nucleolar RNA as the recognition site for the Snu13p-Rrp9p protein pair.	17145781
Analysis of Snu13p mutations reveals differential interactions with the U4 snRNA and U3 snoRNA.	14730029
Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.	34813592
Analysis of the function of E. coli 23S rRNA helix-loop 69 by mutagenesis.	16053518
Antiviral amphipathic oligo- and polyribonucleotides: analogue development and biological studies.	12723951
APOBEC3A is implicated in a novel class of G-to-A mRNA editing in WT1 transcripts.	25807502
Aquifex aeolicus Trm1[tRNA (m2(2)G26) methyltransferase] has a novel recognition mechanism of the substrate RNA.	17150754
Aquifex aeolicus tRNA (N2,N2-guanine)-dimethyltransferase (Trm1) catalyzes transfer of methyl groups not only to guanine 26 but also to guanine 27 in tRNA.	19491098
Arabidopsis N6-methyladenosine methyltransferase FIONA1 regulates floral transition by affecting the splicing of FLC and the stability of floral activators SPL3 and SEP3	36416766
Arabidopsis tRNA adenosine deaminase arginine edits the wobble nucleotide of chloroplast tRNAArg(ACG) and is essential for efficient chloroplast translation.	19602623
Archaeal Pus10 proteins can produce both pseudouridine 54 and 55 in tRNA.	18952823
Archease from Pyrococcus abyssi improves substrate specificity and solubility of a tRNA m5C methyltransferase.	17470432
Architecture of the Human Mitochondrial Iron-Sulfur Cluster Assembly Machinery.	27519411
Architecture of the yeast Elongator complex.	27974378
Architecture of the yeast small subunit processome.	27980088
Archtecture of the yeast small subunit processome	27980088
Artificial intelligence-assisted cryoEM structure of Bfr2-Lcp5 complex observed in the yeast small subunit processome	35650250
Assay of both activities of the bifunctional tRNA-modifying enzyme MnmC reveals a kinetic basis for selective full modification of cmnm5s2U to mnm5s2U.	21306992
Assembly of the archaeal box C/D sRNP can occur via alternative pathways and requires temperature-facilitated sRNA remodeling.	16949610
Assignment of 2'-O-methyltransferases to Modification Sites on the Mammalian Mitochondrial Large Subunit 16S rRNA.	25074936
Association between obesity-related gene FTO and ADHD.	23512716
Asymmetric dimerization of adenosine deaminase acting on RNA facilitates substrate recognition.	32597966
Atomic structure of a folate/FAD-dependent tRNA T54 methyltransferase	19416846
Atomic structure of a folate/FAD-dependent tRNA T54 methyltransferase	19416846
Atomic structure of a folate/FAD-dependent tRNA T54 methyltransferase.	19416846
Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine.	18951093
Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine.	18951093
Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine.	18951093
Backbone resonance assignments of the 48 kDa dimeric putative 18S rRNA-methyltransferase Nep1 from Methanocaldococcus jannaschii.	19779849
Bacterial Hen1 is a 3' terminal RNA ribose 2'-O-methyltransferase component of a bacterial RNA repair cassette.	20007328
Base methylations in the double-stranded RNA by a fused methyltransferase bearing unwinding activity.	22210896
Binding Induced RNA Conformational Changes Control Substrate Recognition and Catalysis by the Thiostrepton-resistance Methyltransferase (Tsr).	25086036
Binding of adenosine-based ligands to the MjDim1 rRNA methyltransferase: implications for reaction mechanism and drug design.	20163168
Binding of adenosine-based ligands to the MjDim1 rRNA methyltransferase: implications for reaction mechanism and drug design.	20163168
Binding of adenosine-based ligands to the MjDim1 rRNA methyltransferase: implications for reaction mechanism and drug design.	20163168
Binding of L7Ae protein to the K-turn of archaeal snoRNAs: a shared RNA binding motif for C/D and H/ACA box snoRNAs in Archaea.	12560482
Binding of the human Prp31 Nop domain to a composite RNA-protein platform in U4 snRNP.	17412961
Binding of the human Prp31 Nop domain to a composite RNA-protein platform in U4 snRNP.	17412961
Biochemical and Computational Analysis of the Substrate Specificities of Cfr and RlmN Methyltransferases	26700482
Biochemical and genetic analysis of RNA cap guanine-N2 methyltransferases from Giardia lamblia and Schizosaccharomyces pombe.	17284461
Biochemical and structural characterization of a thermostable Dps protein with His-type ferroxidase centers and outer metal-binding sites.	32170832
Biochemical and structural insights into the mechanisms of SARS coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex.	22022266
Biochemical characterization of mRNA capping enzyme from Faustovirus	37625853
Biogenesis and growth phase-dependent alteration of 5-methoxycarbonylmethoxyuridine in tRNA anticodons	26681692
Biogenesis and intranuclear trafficking of human box C/D and H/ACA RNPs.	17381323
Biogenesis of 2-agmatinylcytidine catalyzed by the dual protein and RNA kinase TiaS.	22002222
Biogenesis of glutaminyl-mt tRNAGln in human mitochondria.	19805282
Bioinformatic analyses of the tRNA: (guanine 26, N2,N2)-dimethyltransferase (Trm1) family.	12125821
Biosynthesis and function of tRNA modifications in Archaea.	21470902
Biosynthesis of 7-deazaguanosine-modified tRNA nucleosides: a new role for GTP cyclohydrolase I.	18931107
Biosynthesis of a hypermodified nucleotide in Saccharomyces carlsbergensis 17S and HeLa-cell 18S ribosomal ribonucleic acid.	629754
Biosynthesis of archaeosine, a novel derivative of 7-deazaguanosine specific to archaeal tRNA, proceeds via a pathway involving base replacement on the tRNA polynucleotide chain.	9242689
Biosynthesis of selenophosphate.	10609888
Biosynthesis of threonylcarbamoyl adenosine (t6A), a universal tRNA nucleoside.	22378793
Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA.	16642040
Biosynthesis of wyosine derivatives in tRNA(Phe) of Archaea: role of a remarkable bifunctional tRNA(Phe):m1G/imG2 methyltransferase.	24837075
Biosynthesis of wyosine derivatives in tRNA: an ancient and highly diverse pathway in Archaea.	20382657
Box C/D guide RNAs recognize a maximum of 10 nt of substrates	27625427
Box C/D guide RNAs recognize a maximum of 10 nt of substrates	27625427
Box C/D snoRNP catalysed methylation is aided by additional pre-rRNA base-pairing.	21556049
Box H/ACA small ribonucleoproteins.	20227365
Bud23 methylates G1575 of 18S rRNA and is required for efficient nuclear export of pre-40S subunits.	18332120
C-->U editing of neurofibromatosis 1 mRNA occurs in tumors that express both thetype II transcript and apobec-1, the catalytic subunit of the apolipoprotein BmRNA-editing enzyme.	11727199
Caenorhabditis elegans pseudouridine synthase 1 activity in vivo: tRNA is a substrate, but not U2 small nuclear RNA.	12597772
cAMP-dependent transcription of the human CYP21B (P-450C21) gene requires a cis-regulatory element distinct from the consensus cAMP-regulatory element.	2162843
Cap methyltransferase selective binding and methylation of GpppG-RNA are stimulated by importin-alpha.	11114884
Cap-specific terminal -methylation of RNA by an RNA polymerase II-associated methyltransferase.	30467178
Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II-associated methyltransferase.	30467178
Cap-specific, terminal N-methylation by a mammalian mAm methyltransferase.	30487554
Catalysis by the second class of tRNA(m1G37) methyl transferase requires a conserved proline.	16768442
Cbf5p, the putative pseudouridine synthase of H/ACA-type snoRNPs, can form a complex with Gar1p and Nop10p in absence of Nhp2p and box H/ACA snoRNAs.	15388873
CDK13 RNA Over-Editing Mediated by ADAR1 Associates with Poor Prognosis of Hepatocellular Carcinoma Patients.	29996118
cDNA cloning and sequencing of human fibrillarin, a conserved nucleolar protein recognized by autoimmune antisera.	1846968
Cfr and RlmN contain a single [4Fe-4S] cluster, which directs two distinct reactivities for S-adenosylmethionine: methyl transfer by SN2 displacement and radical generation.	21916495
Changes in conformational equilibria regulate the activity of the Dcp2 decapping enzyme.	28533364
Changes of N6-methyladenosine modulators promote breast cancer progression.	30953473
Chapter 21 - Aberrant AID Expression by Pathogen Infection	doi.org/10.1016/B978-0-12-397933-9.00021-7
Characterization and structure of the Aquifex aeolicus protein DUF752: a bacterial tRNA-methyltransferase (MnmC2) functioning without the usually fused oxidase domain (MnmC1)	23091054
Characterization and structure of the Aquifex aeolicus protein DUF752: a bacterial tRNA-methyltransferase (MnmC2) functioning without the usually fused oxidase domain (MnmC1).	23091054
Characterization of a B. subtilis minor isoleucine tRNA deduced from tDNA having a methionine anticodon CAT.	8743586
Characterization of a whole set of tRNA molecules in an aerobic hyper-thermophilic Crenarchaeon, Aeropyrum pernix K1.	16769697
Characterization of GTPase activity of TrmE, a member of a novel GTPase superfamily, from Thermotoga maritima.	11092873
Characterization of hMTr1, a human Cap1 2'-O-ribose methyltransferase.	20713356
Characterization of human, Schizosaccharomyces pombe, and Candida albicans mRNA cap methyltransferases and complete replacement of the yeast capping apparatus by mammalian enzymes.	10347220
Characterization of novel human Intragenic Antimicrobial Peptides, incorporation and release studies from ureasil-polyether hybrid matrix	33321627
Characterization of the 23 S ribosomal RNA m5U1939 methyltransferase from Escherichia coli.	11779873
Characterization of the human tRNA-guanine transglycosylase: confirmation of the heterodimeric subunit structure.	20354154
Characterization of two homologous 2'-O-methyltransferases showing different specificities for their tRNA substrates.	24951554
Characterization of Two Homologous 2'-O-Methyltransferases Showing Different Specificities for Their tRNA Substrates.	24951554
Characterization of Two Homologous 2'-O-Methyltransferases Showing Different Specificities for Their tRNA Substrates.	24951554
Characterization of yeast protein Deg1 as pseudouridine synthase (Pus3) catalyzing the formation of psi 38 and psi 39 in tRNA anticodon loop.	9430663
Chemical Approach for the Study of the ‘Kissing Complex’ of Moloney murine leukaemia Virus	10.1002/hlca.200890133
Chemical incorporation of 1‑methyladenosine into oligonucleotides	11861902
Chemical synthesis of a biologically active natural tRNA with its minor bases.	1383941
Chemical synthesis of RNA including 5-taurinomethyluridine	10.1093/nass/nrl005
Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediate	12949492
Chloroplast development at low temperatures requires a homolog of DIM1, a yeast gene encoding the 18S rRNA dimethylase.	9596631
Chromosome 8 BAC array comparative genomic hybridization and expression analysis identify amplification and overexpression of TRMT12 in breast cancer.	17440925
Cloning and characterization of a p53-related protein kinase expressed in interleukin-2-activated cytotoxic T-cells, epithelial tumor cell lines, and the testes.	11546806
Cloning and characterization of an aminoglycoside resistance determinant from Micromonospora zionensis.	1447159
Cloning and characterization of the 23S RNA pseudouridine 2633 synthase from Bacillus subtilis.	9888802
Cloning and characterization of the Schizosaccharomyces pombe tRNA:pseudouridine synthase Pus1p.	11095668
Cloning and characterization of three human cDNAs encoding mRNA (guanine-7-)-methyltransferase, an mRNA cap methylase.	9790902
Cloning and characterization of tRNA (m1A58) methyltransferase (TrmI) from Thermus thermophilus HB27, a protein required for cell growth at extreme temperatures.	12682365
Cloning and characterization of two human cDNAs encoding the mRNA capping enzyme.	9473487
Cloning and mapping of a human novel cDNA (NHP2L1) that encodes a protein highly homologous to yeast nuclear protein NHP2.	8978773
Cloning and restriction mapping of the trmA gene coding for transfer ribonucleic acid (5-methyluridine)-methyltransferase in Escherichia coli K-12.	6247318
Cloning of a human tRNA isopentenyl transferase.	11111046
Cloning of an Apobec-1-binding protein that also interacts with apolipoprotein B mRNA and evidence for its involvement in RNA editing	8999813
Cocrystal structure of a tRNA Psi55 pseudouridine synthase: nucleotide flipping by an RNA-modifying enzyme.	11779468
Common thiolation mechanism in the biosynthesis of tRNA thiouridine and sulphur-containing cofactors.	19037260
Comparative analysis of the 15.5kD box C/D snoRNP core protein in the primitive eukaryote Giardia lamblia reveals unique structural and functional features.	21366326
Comparative analysis of the 15.5kD box C/D snoRNP core protein in the primitive eukaryote Giardia lamblia reveals unique structural and functional features.	21366326
Complete chemical structures of human mitochondrial tRNAs	32859890
Comprehensive phylogenetic analysis of evolutionarily conserved rRNA adenine dimethyltransferase suggests diverse bacterial contributions to the nucleus-encoded plastid proteome.	19017544
Conformational change of pseudouridine 55 synthase upon its association with RNA substrate.	14990747
Conformational communication mediates the reset step in t6A biosynthesis.	31114923
Conformational proofreading of distant 40S ribosomal subunit maturation events by a long-range communication mechanism.	31227701
Conformational Stability Adaptation of a Double-Stranded RNA-Binding Domain to Transfer RNA Ligand.	31045345
Conformational Switch Regulates the DNA Cytosine Deaminase Activity of Human APOBEC3B.	29234087
Conformational Switch Regulates the DNA Cytosine Deaminase Activity of Human APOBEC3B.	29234087
Conformational switches control early maturation of the eukaryotic small ribosomal subunit.	31206356
Conservation of an intricate circuit for crucial modifications of the tRNAPhe anticodon loop in eukaryotes.	25404562
Conservation of structure and mechanism by Trm5 enzymes.	23887145
Conserved amino acids in each subunit of the heteroligomeric tRNA m1A58 Mtase from Saccharomyces cerevisiae contribute to tRNA binding.	17932071
Conserved cysteine residues of GidA are essential for biogenesis of 5-carboxymethylaminomethyluridine at tRNA anticodon	19446527
Conserved cysteine residues of GidA are essential for biogenesis of 5-carboxymethylaminomethyluridine at tRNA anticodon	19446527
Conserved cysteine residues of GidA are essential for biogenesis of 5-carboxymethylaminomethyluridine at tRNA anticodon.	19446527
Conserved network of proteins essential for bacterial viability.	19376873
Conserved P-loop GTPases of unknown function in bacteria: an emerging and vital ensemble in bacterial physiology.	16333325
Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis.	32668200
Control of catalytic cycle by a pair of analogous tRNA modification enzymes.	20452364
Control of human potassium channel inactivation by editing of a small mRNA hairpin.	15361858
Control of substrate specificity by a single active site residue of the KsgA methyltransferase.	22142337
Control of Substrate Specificity by a Single Active Site Residue of the KsgA Methyltransferase.	22142337
Coordinate expression of NADPH-dependent flavin reductase, Fre-1, and Hint-related 7meGMP-directed hydrolase, DCS-1.	12871939
Coupling of N7-methyltransferase and 3'-5' exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading.	34143953
Covalent Intermediate in the Catalytic Mechanism of the Radical S-Adenosyl-l-methionine Methyl Synthase RlmN Trapped by Mutagenesis.	23088750
Critical residues for cofactor binding and catalytic activity in the aminoglycoside resistance methyltransferase Sgm.	18586937
Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states.	32943522
Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation	287811266
Cryo-EM Structure of an Extended SARS-CoV-2 Replication and Transcription Complex Reveals an Intermediate State in Cap Synthesis.	33232691
Cryo-EM Structure of an Extended SARS-CoV-2 Replication and Transcription Complex Reveals an Intermediate State in Cap Synthesis.	33232691
Cryo-EM structure of the EBV ribonucleotide reductase BORF2 and mechanism of APOBEC3B inhibition.	35476445
Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution.	26829225
Cryo-EM structures of human m6A writer complexes.	36167981
CryoEM structure of the low-complexity domain of hnRNPA2 and its conversion to pathogenic amyloid	32796831
Crystal and solution structures of methyltransferase RsmH provide basis for methylation of C1402 in 16S rRNA.	22561317
Crystal and solution structures of methyltransferase RsmH provide basis for methylation of C1402 in 16S rRNA.	22561317
Crystal structure and cap binding analysis of the methyltransferase of langat virus	36347437
Crystal structure and functional analysis of Dcp2p from Schizosaccharomyces pombe	16341225
Crystal Structure and Functional Analysis of the Sars-Coronavirus RNA CAP 2'-O-Methyltransferase Nsp10/Nsp16 Complex.	21637813
Crystal structure and mutational study of a unique SpoU family archaeal methylase that forms 2'-O-methylcytidine at position 56 of tRNA	18068186
Crystal structure and mutational study of a unique SpoU family archaeal methylase that forms 2'-O-methylcytidine at position 56 of tRNA.	18068186
Crystal structure and RNA binding properties of the RNA recognition motif (RRM) and AlkB domains in human AlkB homolog 8 (ABH8), an enzyme catalyzing tRNA hypermodification.	22065580
Crystal structure and RNA binding properties of the RNA recognition motif (RRM) and AlkB domains in human AlkB homolog 8 (ABH8), an enzyme catalyzing tRNA hypermodification.	22065580
Crystal structure and RNA binding properties of the RNA recognition motif (RRM) and AlkB domains in human AlkB homolog 8 (ABH8), an enzyme catalyzing tRNA hypermodification.	22065580
Crystal structure of a Cbf5-Nop10-Gar1 complex and implications in RNA-guided pseudouridylation and dyskeratosis congenita.	16427014
Crystal structure of a fibrillarin homologue from Methanococcus jannaschii, a hyperthermophile, at 1.6 A resolution.	10654930
Crystal structure of a fibrillarin homologue from Methanococcus jannaschii, a hyperthermophile, at 1.6 A resolution.	10654930
Crystal structure of a junction between B-DNA and Z-DNA reveals two extruded bases.	6237447
Crystal structure of a junction between two Z-DNA helices.	20439751
Crystal structure of a novel JmjC-domain-containing protein, TYW5, involved in tRNA modification.	20972222
Crystal structure of a novel JmjC-domain-containing protein, TYW5, involved in tRNA modification.	20972222
Crystal structure of a novel JmjC-domain-containing protein, TYW5, involved in tRNA modification.	20972222
Crystal structure of a Y-box binding protein 1 (YB-1)-RNA complex reveals key features and residues interacting with RNA.	31160337
Crystal structure of an H/ACA box ribonucleoprotein particle	16943774
Crystal structure of an RluF-RNA complex: a base-pair rearrangement is the key to selectivity of RluF for U2604 of the ribosome.	19298824
Crystal structure of an RluF-RNA complex: a base-pair rearrangement is the key to selectivity of RluF for U2604 of the ribosome.	19298824
Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity.	28452355
Crystal structure of archaeal tRNA(m(1)G37)methyltransferase aTrm5.	18384044
Crystal structure of archaeal tRNA(m(1)G37)methyltransferase aTrm5.	18384044
Crystal structure of archaeosine tRNA-guanine transglycosylase.	12054814
Crystal structure of archaeosine tRNA-guanine transglycosylase.	12054814
Crystal structure of Bacillus anthracis ThiI, a tRNA-modifying enzyme containing the predicted RNA-binding THUMP domain.	16343540
Crystal structure of Bacillus subtilis S-adenosylmethionine:tRNA ribosyltransferase-isomerase.	17083917
Crystal structure of Bacillus subtilis TrmB, the tRNA (m7G46) methyltransferase.	16600901
Crystal structure of Bacillus subtilis TrmB, the tRNA (m7G46) methyltransferase.	16600901
Crystal structure of DNA cytidine deaminase ABOBEC3G catalytic deamination domain suggests a binding mode of full-length enzyme to single-stranded DNA	25542899
Crystal structure of elongator subcomplex Elp4-6	22556426
Crystal structure of ErmC', an rRNA methyltransferase which mediates antibiotic resistance in bacteria.	9585521
Crystal structure of ErmC', an rRNA methyltransferase which mediates antibiotic resistance in bacteria.	9585521
Crystal structure of ErmE - 23S rRNA methyltransferase in macrolide resistance.	31601908
Crystal structure of ErmE - 23S rRNA methyltransferase in macrolide resistance.	31601908
Crystal structure of glutamyl-queuosine tRNAAsp synthetase complexed with L-glutamate: structural elements mediating tRNA-independent activation of glutamate and glutamylation of tRNAAsp anticodon.	18602926
Crystal Structure of Glutamyl-Queuosine Trnaasp Synthetase Complexed with L-Glutamate: Structural Elements Mediating tRNA-Independent Activation of Glutamate and Glutamylation of Trnaasp Anticodon.	18602926
Crystal structure of human ABAD/HSD10 with a bound inhibitor: implications for design of Alzheimer's disease therapeutics	15342248
Crystal structure of human cytoplasmic tRNAHis-specific 5'-monomethylphosphate capping enzyme.	31919512
Crystal structure of human diphosphoinositol phosphatase 1	19585659
Crystal structure of human diphosphoinositol phosphatase 1.	19585659
Crystal structure of human METTL6, the m3C methyltransferase	34862464
Crystal structure of human Pus10, a novel pseudouridine synthase.	17900615
Crystal Structure of Human Pus10, a Novel Pseudouridine Synthase.	17900615
Crystal structure of human YTHDC2 YTH domain.	31472957
Crystal structure of IscA, an iron-sulfur cluster assembly protein from Escherichia coli.	15050828
Crystal structure of IscA, an iron-sulfur cluster assembly protein from Escherichia coli.	15050828
Crystal Structure of IscS, a Cysteine Desulfurase from Escherichia coli	12860127
Crystal structure of IscS, a cysteine desulfurase from Escherichia coli.	12860127
Crystal structure of KsgA, a universally conserved rRNA adenine dimethyltransferase in Escherichia coli	15136037
Crystal structure of KsgA, a universally conserved rRNA adenine dimethyltransferase in Escherichia coli.	15136037
Crystal structure of Methanocaldococcus jannaschii Trm4 complexed with sinefungin.	20600111
Crystal structure of Mj1640/DUF358 protein reveals a putative SPOUT-class RNA methyltransferase	21098051
Crystal structure of Mj1640/DUF358 protein reveals a putative SPOUT-class RNA methyltransferase.	21098051
Crystal Structure of Non-Structural Protein 10 from Severe Acute Respiratory Syndrome Coronavirus-2.	33036230
Crystal structure of pseudouridine synthase RluA: indirect sequence readout through protein-induced RNA structure	17188032
Crystal structure of pseudouridine synthase RluA: indirect sequence readout through protein-induced RNA structure.	17188032
Crystal structure of QueC from Bacillus subtilis: an enzyme involved in preQ1 biosynthesis.	18491386
Crystal structure of RlmAI: implications for understanding the 23S rRNA G745/G748-methylation at the macrolide antibiotic-binding site.	14999102
Crystal structure of RlmAI: implications for understanding the 23S rRNA G745/G748-methylation at the macrolide antibiotic-binding site.	14999102
Crystal Structure of Rlmm, the 2'O-Ribose Methyltransferase for C2498 of Escherichia Coli 23S Rrna	22923526
Crystal Structure of RNA 3'-Terminal Phosphate Cyclase, a Ubiquitous Enzyme with Unusual Topology	10673421
Crystal structure of RumA, an iron-sulfur cluster containing E. coli ribosomal RNA 5-methyluridine methyltransferase.	15016356
Crystal Structure of Ruma, an Iron-Sulfur Cluster Containing E. Coli Ribosomal RNA 5-Methyluridine Methyltransferase.	15016356
Crystal structure of Rv2118c: an AdoMet-dependent methyltransferase from Mycobacterium tuberculosis H37Rv.	11554794
Crystal structure of Rv2118c: an AdoMet-dependent methyltransferase from Mycobacterium tuberculosis H37Rv.	11554794
Crystal structure of S-adenosylmethionine:tRNA ribosyltransferase-isomerase (QueA) from Thermotoga maritima at 2.0 A resolution reveals a new fold.	15822125
Crystal structure of SARS-CoV-2 nsp10 bound to nsp14-ExoN domain reveals an exoribonuclease with both structural and functional integrity.	33956156
Crystal structure of SARS-CoV-2 nsp10 bound to nsp14-ExoN domain reveals an exoribonuclease with both structural and functional integrity.	33956156
Crystal structure of Staphylococcus aureus tRNA adenosine deaminase TadA in complex with RNA.	16415880
Crystal structure of Sulfolobus tokodaii Sua5 complexed with L-threonine and AMPPNP.	21538543
Crystal structure of the ancient, Fe-S scaffold IscA reveals a novel protein fold.	14705938
Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications.	18849968
Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications.	18849968
Crystal structure of the apo forms of psi 55 tRNA pseudouridine synthase from Mycobacterium tuberculosis: a hinge at the base of the catalytic cleft.	15028724
Crystal Structure of the APOBEC3G Catalytic Domain Reveals Potential Oligomerization Interfaces.	20152150
Crystal Structure of the Avilamycin Resistance-Conferring Methyltransferase Avira from Streptomyces Viridochromogenes	12742024
Crystal structure of the avilamycin resistance-conferring methyltransferase AviRa from Streptomyces viridochromogenes.	12742024
Crystal structure of the bifunctional tRNA modification enzyme MnmC from Escherichia coli	21574198
Crystal structure of the bifunctional tRNA modification enzyme MnmC from Escherichia coli.	21574198
Crystal structure of the catalytic domain of HIV-1 restriction factor APOBEC3G in complex with ssDNA.	29941968
Crystal structure of the catalytic domain of RluD, the only rRNA pseudouridine synthase required for normal growth of Escherichia coli	14730022
Crystal structure of the catalytic domain of RluD, the only rRNA pseudouridine synthase required for normal growth of Escherichia coli.	14730022
Crystal structure of the dimeric Urm1 from the yeast Saccharomyces cerevisiae	18260097
Crystal Structure of the DNA Cytosine Deaminase APOBEC3F: The Catalytically Active and HIV-1 Vif-Binding Domain.	23685212
Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain.	26416889
Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain.	26416889
Crystal structure of the Escherichia coli 23S rRNA:m5C methyltransferase RlmI (YccW) reveals evolutionary links between RNA modification enzymes	18789337
Crystal structure of the Escherichia coli 23S rRNA:m5C methyltransferase RlmI (YccW) reveals evolutionary links between RNA modification enzymes.	18789337
Crystal structure of the Escherichia coli glucose-inhibited division protein B (GidB) reveals a methyltransferase fold.	12001236
Crystal structure of the Escherichia coli glucose-inhibited division protein B (GidB) reveals a methyltransferase fold.	12001236
Crystal structure of the FTO protein reveals basis for its substrate specificity	20376003
Crystal structure of the FTO protein reveals basis for its substrate specificity.	20376003
Crystal structure of the highly divergent pseudouridine synthase TruD reveals a circular permutation of a conserved fold.	15208439
Crystal structure of the highly divergent pseudouridine synthase TruD reveals a circular permutation of a conserved fold.	15208439
Crystal structure of the human PRPK-TPRKB complex.	33547416
Crystal Structure of the Human tRNA Guanine Transglycosylase Catalytic Subunit QTRT1.	30149595
Crystal Structure of the Human tRNA Guanine Transglycosylase Catalytic Subunit QTRT1.	30149595
Crystal Structure of the Human tRNA m(1)A58 Methyltransferase-tRNA3(Lys) Complex: Refolding of Substrate tRNA Allows Access to the Methylation Target.	26470919
Crystal Structure of the Human tRNA m(1)A58 Methyltransferase-tRNA3(Lys) Complex: Refolding of Substrate tRNA Allows Access to the Methylation Target.	26470919
Crystal Structure of the Human tRNA mA58 Methyltransferase-tRNA Complex: Refolding of Substrate tRNA allows Access to the Methylation Target.	26470919
Crystal Structure of the Nosiheptide-Resistance Methyltransferase of Streptomyces actuosus	20550164
Crystal structure of the radical SAM enzyme catalyzing tricyclic modified base formation in tRNA.	17727881
Crystal structure of the RluD pseudouridine Synthase catalytic module, an enzyme that modifies 23S rRNA and is essential for normal cell growth of Escherichia coli	14659742
Crystal structure of the RluD pseudouridine synthase catalytic module, an enzyme that modifies 23S rRNA and is essential for normal cell growth of Escherichia coli.	14659742
Crystal structure of the RNA demethylase ALKBH5 from zebrafish.	24561204
Crystal Structure of the Spliceosomal 15.5Kd Protein Bound to a U4 Snrna Fragment	11163207
Crystal structure of the spliceosomal 15.5kD protein bound to a U4 snRNA fragment.	11163207
Crystal structure of the Thermus thermophilus 16 S rRNA methyltransferase RsmC in complex with cofactor and substrate guanosine.	18667428
Crystal structure of the transcription factor sc-mtTFB offers insights into mitochondrial transcription.	11567089
Crystal structure of the transcription factor sc-mtTFB offers insights into mitochondrial transcription.	11567089
Crystal structure of the Tum1 protein from the yeast Saccharomyces cerevisiae.	22587783
Crystal structure of the two-subunit tRNA m(1)A58 methyltransferase TRM6-TRM61 from Saccharomyces cerevisiae.	27582183
Crystal structure of the YTH domain of YTHDF2 reveals mechanism for recognition of N6-methyladenosine.	25412661
Crystal structure of the Zalpha domain of the human editing enzyme ADAR1 bound to left-handed Z-DNA.	10364558
Crystal Structure of Thermus thermophilus tRNA m(1)A(58) Methyltransferase and Biophysical Characterization of Its Interaction with tRNA.	18262540
Crystal structure of Thermus thermophilus tRNA m1A58 methyltransferase and biophysical characterization of its interaction with tRNA.	18262540
Crystal structure of tRNA adenosine deaminase (TadA) from Aquifex aeolicus.	15677468
Crystal structure of tRNA m1G9 methyltransferase Trm10: insight into the catalytic mechanism and recognition of tRNA substrate	24081582
Crystal structure of tRNA m1G9 methyltransferase Trm10: insight into the catalytic mechanism and recognition of tRNA substrate.	24081582
Crystal Structure of tRNA N(2),N(2)-Guanosine Dimethyltransferase Trm1 from Pyrococcus horikoshii	18789948
Crystal Structure of tRNA N(2),N(2)-Guanosine Dimethyltransferase Trm1 from Pyrococcus horikoshii	18789948
Crystal structure of tRNA N2,N2-guanosine dimethyltransferase Trm1 from Pyrococcus horikoshii.	18789948
Crystal structure of tRNA pseudouridine synthase TruA from Thermus thermophilus HB8.	17114947
Crystal structure of tRNA-guanine transglycosylase: RNA modification by base exchange.	8654383
Crystal structure of TruD, a novel pseudouridine synthase with a new protein fold	14999002
Crystal structure of TruD, a novel pseudouridine synthase with a new protein fold.	14999002
Crystal structure of YecO from Haemophilus influenzae (HI0319) reveals a methyltransferase fold and a bound S-adenosylhomocysteine.	11746687
Crystal structure of YecO from Haemophilus influenzae (HI0319) reveals a methyltransferase fold and a bound S-adenosylhomocysteine.	11746687
Crystal structures of human DcpS in ligand-free and m7GDP-bound forms suggest a dynamic mechanism for scavenger mRNA decapping.	15769464
Crystal Structures of Human RNA Demethylase Alkbh5 Reveal Basis for Substrate Recognition.	24616105
Crystal structures of the bifunctional tRNA methyltransferase Trm5a	27629654
Crystal structures of the catalytic domains of pseudouridine synthases RluC and RluD from Escherichia coli	15078091
Crystal structures of the catalytic domains of pseudouridine synthases RluC and RluD from Escherichia coli.	15078091
Crystal structures of the conserved tRNA-modifying enzyme GidA: implications for its interaction with MnmE and substrate.	18565343
Crystal structures of the conserved tRNA-modifying enzyme GidA: implications for its interaction with MnmE and substrate	18565343
Crystal structures of the conserved tRNA-modifying enzyme GidA: implications for its interaction with MnmE and substrate	18565343
Crystal structures of the Gon7/Pcc1 and Bud32/Cgi121 complexes provide a model for the complete yeast KEOPS complex.	25735745
Crystal structures of the human RNA demethylase Alkbh5 reveal basis for substrate recognition	24616105
Crystal structures of the human RNA demethylase Alkbh5 reveal basis for substrate recognition	24616105
Crystal structures of the tRNA:m2G6 methyltransferase Trm14/TrmN from two domains of life.	22362751
Crystal structures of the tRNA:m2G6 methyltransferase Trm14/TrmN from two domains of life.	22362751
Crystal structures of tRNA-guanine transglycosylase (TGT) in complex with novel and potent inhibitors unravel pronounced induced-fit adaptations and suggest dimer formation upon substrate binding.	17524419
Crystallization and characterization of a fragment of pseudouridine synthase RluC from Escherichia coli.	10089432
Crystallization and preliminary crystallographic analysis of nosiheptide-resistance methyltransferase from Streptomyces actuosus in complex with SAM.	20445264
Crystallization and preliminary X-ray characterization of queD from Bacillus subtilis, an enzyme involved in queuosine biosynthesis.	18259064
Crystallization and preliminary X-ray characterization of the nitrile reductase QueF: a queuosine-biosynthesis enzyme.	16511203
Crystallographic snapshots of eukaryotic dimethylallyltransferase acting on tRNA: insight into tRNA recognition and reaction mechanism.	18852462
Cysteine of sequence motif VI is essential for nucleophilic catalysis by yeast tRNA m5C methyltransferase.	17475914
Cytosine-5 RNA methylation links protein synthesis to cell metabolism.	31199786
DcpS as a therapeutic target for spinal muscular atrophy.	18839960
DcpS can act in the 5'-3' mRNA decay pathway in addition to the 3'-5' pathway.	14523240
Decapping Enzyme NUDT12 Partners with BLMH for Cytoplasmic Surveillance of NAD-Capped RNAs.	31875550
Decapping reaction of mRNA requires Dcp1 in fission yeast: its characterization in different species from yeast to human.	15671491
Deciphering Determinants in Ribosomal Methyltransferases That Confer Antimicrobial Resistance	30624914
Decoding the Mechanism of Specific RNA Targeting by Ribosomal Methyltransferases.	35316014
Deduced RNA binding mechanism of ThiI based on structural and binding analyses of a minimal RNA ligand.	19509301
Deep Knot Structure for Construction of Active Site and Cofactor Binding Site of tRNA Modification Enzyme	15062082
Deep knot structure for construction of active site and cofactor binding site of tRNA modification enzyme.	15062082
Defects in t 6 A tRNA modification due to GON7 and YRDC mutations lead to Galloway-Mowat syndrome.	31481669
Defects in tRNA Anticodon Loop 2'-O-Methylation Are Implicated in Nonsyndromic X-Linked Intellectual Disability due to Mutations in FTSJ1.	26310293
Deficient methylation and formylation of mt-tRNA(Met) wobble cytosine in a patient carrying mutations in NSUN3.	27356879
Deficit of tRNA(Lys) modification by Cdkal1 causes the development of type 2 diabetes in mice.	21841312
Deletion of gene encoding methyltransferase (gidB) confers high-level antimicrobial resistance in Salmonella.	22318332
Deletion of the Escherichia coli pseudouridine synthase gene truB blocks formation of pseudouridine 55 in tRNA in vivo, does not affect exponential growth, but confers a strong selective disadvantage in competition with wild-type cells.	11142385
Deletion of the MTO2 gene related to tRNA modification causes a failure in mitochondrial RNA metabolism in the yeast Saccharomyces cerevisiae.	17706197
Determinants of the CmoB carboxymethyl transferase utilized for selective tRNA wobble modification.	25855808
Determinants of the CmoB carboxymethyl transferase utilized for selective tRNA wobble modification.	25855808
Determinants of the CmoB carboxymethyl transferase utilized for selective tRNA wobble modification.	25855808
Determinants of tRNA editing and modification: Avoiding conundrums, affecting function.	22024020
Determination of DNA and RNA Methylation in Circulating Tumor Cells by Mass Spectrometry.	26707930
Determination of queuosine derivatives by reverse-phase liquid chromatography for the hypomodification study of Q-bearing tRNAs from various mammal liver cells.	14751792
Determination of the target nucleosides for members of two families of 16S rRNA methyltransferases that confer resistance to partially overlapping groups of aminoglycoside antibiotics.	19589804
Development of metachronous rectal cancers in a young man with dyskeratosis congenita: a case report.	31027506
Different mechanisms for pseudouridine formation in yeast 5S and 5.8S rRNAs.	18332121
Differential roles of archaeal box H/ACA proteins in guide RNA-dependent and independent pseudouridine formation.	17993784
Differential roles of human PUS10 in miRNA processing and tRNA pseudouridylation.	31819270
Differentiating analogous tRNA methyltransferases by fragments of the methyl donor.	21602303
Dim1p is required for efficient splicing and export of mRNA encoding lid1p, a component of the fission yeast anaphase-promoting complex.	15755920
Dim2p, a KH-domain protein required for small ribosomal subunit synthesis.	15037774
Dimerisation-dependent GTPase reaction of MnmE: how potassium acts as GTPase-activating element.	16763562
Dimerisation-dependent GTPase reaction of MnmE: how potassium acts as GTPase-activating element.	16763562
Dimerization of elongator protein 1 is essential for Elongator complex assembly.	26261306
Direct evidence for enzyme persulfide and disulfide intermediates during 4-thiouridine biosynthesis.	16855700
Direct evidence that ThiI is an ATP pyrophosphatase for the adenylation of uridine in 4-thiouridine biosynthesis.	18604845
Discovery and biological characterization of geranylated RNA in bacteria.	22983156
Discovery and characterization of an amidinotransferase involved in the modification of archaeal tRNA.	20129918
Discovery and characterization of tRNAIle lysidine synthetase (TilS).	19944692
Discovery of a gene family critical to wyosine base formation in a subset of phenylalanine-specific transfer RNAs.	16162496
Discovery of epoxyqueuosine (oQ) reductase reveals parallels between halorespiration and tRNA modification.	21502530
Discovery of the beta-barrel-type RNA methyltransferase responsible for N6-methylation of N6-threonylcarbamoyladenosine in tRNAs.	25063302
Disruption and functional analysis of six ORFs of chromosome IV: YDL103c (QRI1), YDL105w (QRI2), YDL112w (TRM3), YDL113c, YDL116w (NUP84) and YDL167c (NRP1).	11180460
Dissecting the roles of a strictly conserved tyrosine in substrate recognition and catalysis by pseudouridine 55 synthase	16300397
Distinct iron-sulfur cluster assembly complexes exist in the cytosol and mitochondria of human cells.	11060020
Distinct substrate specificities of the human tRNA methyltransferases TRMT10A and TRMT10B.	31292261
Distinct tRNA modifications in the thermo-acidophilic archaeon, Thermoplasma acidophilum.	24076028
Division of labour: tRNA methylation by the NSun2 tRNA methyltransferases Trm4a and Trm4b in fission yeast.	30646830
Dodecamer Structure of Severe Acute Respiratory Syndrome Coronavirus Nonstructural Protein nsp10	16873247
Doing it in reverse: 3'-to-5' polymerization by the Thg1 superfamily.	22456265
Domain Organization and Crystal Structure of the Catalytic Domain of E.coli RluF, a Pseudouridine Synthase that Acts on 23S rRNA	16712869
Domain organization and crystal structure of the catalytic domain of E.coli RluF, a pseudouridine synthase that acts on 23S rRNA.	16712869
Domain V of 23S rRNA contains all the structural elements necessary for recognition by the ErmE methyltransferase.	7961464
Down-Regulation of m6A mRNA Methylation Is Involved in Dopaminergic Neuronal Death.	30835997
Downregulation of N-methyladenosine binding YTHDF2 protein mediated by miR-493-3p suppresses prostate cancer by elevating N-methyladenosine levels.	29423080
DrosophilaYBX1 homolog YPS promotes ovarian germ line stem cell development by preferentially recognizing 5-methylcytosine RNAs.	32015133
Dual conformational recognition by Z-DNA binding protein is important for the B-Z transition process.	33245772
Dynamic association of capping enzymes with transcribing RNA polymerase II.	11018011
Dynamic inosinome profiles reveal novel patient stratification and gender-specific differences in glioblastoma.	30760294
Dynamic mA mRNA methylation reveals the role of METTL3-mA-CDCP1 signaling axis in chemical carcinogenesis.	30796352
Dynamic modulation of Dnmt2-dependent tRNA methylation by the micronutrient queuine.	26424849
Dynamics of RNA modification by a multi-site-specific tRNA methyltransferase.	25217588
Dysregulated N6-methyladenosine methylation writer METTL3 contributes to the proliferation and migration of gastric cancer.	31232471
Dysregulated N6-methyladenosine methylation writer METTL3 contributes to the proliferation and migration of gastric cancer.	31232471
Early-onset epilepsy and postnatal lethality associated with an editing-deficientGluR-B allele in mice.	7502080
Editing modifies the GABAA receptor subunit α3	17369310
Effect of a mutation in the anticodon of human mitochondrial tRNAPro on its post-transcriptional modification pattern.	9421512
Effects of mutagenesis in the switch I region and conserved arginines of Escherichia coli MnmE protein, a GTPase involved in tRNA modification.	15983041
Effects on transcription of mutations in ygjD, yeaZ, and yjeE genes, which are involved in a universal tRNA modification in Escherichia coli.	21873492
Ein neuer Zugang zu 2’-O-Alkylribonucleosiden und Eigenschaften deren Oligonucleotide	10.1002/hlca.19950780219
Electrostatic Potential in the tRNA Binding Evolution of Dihydrouridine Synthases.	30149704
Electrostatic Potential in the tRNA Binding Evolution of Dihydrouridine Synthases.	30149704
Elongator complex influences telomeric gene silencing and DNA damage response by its role in wobble uridine tRNA modification.	21912530
Elongator, a multisubunit component of a novel RNA polymerase II holoenzyme for transcriptional elongation.	10024884
Emerging themes in radical SAM chemistry.	23141873
Enzymatic characterization of three human RNA adenosine methyltransferases reveals diverse substrate affinities and reaction optima	33428944
Enzymatic formation of queuosine and of glycosyl queuosine in yeast tRNAs microinjected into Xenopus laevis oocytes. The effect of the anticodon loop sequence.	3117541
Enzymatic modification of tRNAs: MiaB is an iron-sulfur protein.	11882645
Enzymatic synthesis of Q nucleoside containing mannose in the anticodon of tRNA: isolation of a novel mannosyltransferase from a cell-free extract of rat liver.	20603
Enzymology of tRNA modification in the bacterial MnmEG pathway.	22386868
Epigenetic control of rDNA loci in response to intracellular energy status	18485871
Epigenetic loss of m1A RNA demethylase ALKBH3 in Hodgkin lymphoma targets collagen, conferring poor clinical outcome.	32915956
Epigenetic loss of RNA-methyltransferase NSUN5 in glioma targets ribosomes to drive a stress adaptive translational program	31428936
ErmE methyltransferase recognizes features of the primary and secondary structure in a motif within domain V of 23 S rRNA.	9973557
Escherichia coli dimethylallyl diphosphate:tRNA dimethylallyltransferase: a binding mechanism for recombinant enzyme.	9012675
Escherichia coli dimethylallyl diphosphate:tRNA dimethylallyltransferase: essential elements for recognition of tRNA substrates within the anticodon stem-loop.	10828971
Escherichia coli mutant SELD enzymes. The cysteine 17 residue is essential for selenophosphate formation from ATP and selenide.	1527085
Escherichia coli QueD is a 6-carboxy-5,6,7,8-tetrahydropterin synthase.	19231875
Essential role of METTL3-mediated mA modification in glioma stem-like cells maintenance and radioresistance.	28991227
Essential role of METTL3-mediated mA modification in glioma stem-like cells maintenance and radioresistance.	28991227
Eukaryotic stand-alone pseudouridine synthases – RNA modifying enzymes and emerging regulators of gene expression?	28045575
Eukaryotic wobble uridine modifications promote a functionally redundant decoding system.	18332122
Evidence for an early gene duplication event in the evolution of the mitochondrial transcription factor B family and maintenance of rRNA methyltransferase activity in human mtTFB1 and mtTFB2.	17031457
Evidence for natural gene transfer from gram-positive cocci to Escherichia coli.	2832378
Evidence for the transfer of sulfane sulfur from IscS to ThiI during the in vitro biosynthesis of 4-thiouridine in Escherichia coli tRNA.	10753862
Evidence that the folate-dependent proteins YgfZ and MnmEG have opposing effects on growth and on activity of the iron-sulfur enzyme MiaB.	22081392
Evidence that ThiI, an enzyme shared between thiamin and 4-thiouridine biosynthesis, may be a sulfurtransferase that proceeds through a persulfide intermediate.	10722656
Evolutionarily conserved proteins MnmE and GidA catalyze the formation of two methyluridine derivatives at tRNA wobble positions.	19767610
Evolutionary conservation of the human nucleolar protein fibrillarin and its functional expression in yeast.	2026646
Expanded tRNA methyltransferase family member TRMT9B regulates synaptic growth and function	37642556
Expanding role of the jumonji C domain as an RNA hydroxylase.	20739293
Expanding the Kinome World: A New Protein Kinase Family Widely Conserved in Bacteria	28890133
Expression and analysis of the SAM-dependent RNA methyltransferase Rsm22 from Saccharomyces cerevisiae.	34076597
Expression and purification of untagged and histidine-tagged folate-dependent tRNA:m5U54 methyltransferase from Bacillus subtilis.	20412857
Expression and roles of Wilms' tumor 1-associating protein in glioblastoma.	22957919
Expression and roles of Wilms' tumor 1-associating protein in glioblastoma.	22957919
Expression of Demethylase Genes, FTO and ALKBH1, Is Associated with Prognosis of Gastric Cancer.	30637548
Expression of Demethylase Genes, FTO and ALKBH1, Is Associated with Prognosis of Gastric Cancer.	30637548
Expression of the mRNA (N6-adenosine)-methyltransferase S-adenosyl-L-methionine binding subunit mRNA in cultured cells.	11470232
Expression profiles and prognostic significance of RNA N6-methyladenosine-related genes in patients with hepatocellular carcinoma: evidence from independent datasets	31118805
Expression profiles and prognostic significance of RNA N6-methyladenosine-related genes in patients with hepatocellular carcinoma: evidence from independent datasets.	31118805
Expression, purification and preliminary X-ray analysis of a fibrillarin homolog from Methanococcus jannaschii, a hyperthermophile.	10089444
Extensive 5'-surveillance guards against non-canonical NAD-caps of nuclear mRNAs in yeast.	33139726
FAD/Folate-Dependent tRNA Methyltransferase: Flavin as a new methyl-transfer agent.	23157377
Family background of children with Down's syndrome and of children with a similar degree of mental retardation.	2946350
Fat mass and obesity-associated (FTO) protein regulates adult neurogenesis.	28398475
Fat mass-and obesity-associated (FTO) gene variant is associated with obesity: longitudinal analyses in two cohort studies and functional test.	18647953
FICC-Seq: a method for enzyme-specified profiling of methyl-5-uridine in cellular RNA.	31361898
Fine-tuning of the ribosomal decoding center by conserved methyl-modifications in the Escherichia coli 16S rRNA.	19965768
FIONA1 is an RNA N6-methyladenosine methyltransferase affecting Arabidopsis photomorphogenesis and flowering	35101091
FIONA1-Mediated m6 A Modification Regulates the Floral Transition in Arabidopsis	34989479
First-In-Class Small Molecule Inhibitors of the Single-Strand DNA Cytosine Deaminase APOBEC3G.	22181350
First-In-Class Small Molecule Inhibitors of the Single-Strand DNA Cytosine Deaminase APOBEC3G.	22181350
Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein	26457839
Fluorescent properties of an unnatural nucleobase, 2-amino-6-(2-thienyl)purine, in DNA and RNA fragments.	17150745
Formation of m2G6 in Methanocaldococcus jannaschii tRNA catalyzed by the novel methyltransferase Trm14.	21693558
Formation of the conserved pseudouridine at position 55 in archaeal tRNA.	16920741
Formation of thiolated nucleosides present in tRNA from Salmonella enterica serovar Typhimurium occurs in two principally distinct pathways.	14729702
FoxM1 Drives a Feed-Forward STAT3-Activation Signaling Loop That Promotes the Self-Renewal and Tumorigenicity of Glioblastoma Stem-like Cells.	25832656
Fragment Ligands of the m 6 A-RNA Reader YTHDF2.	36110386
From bacterial to human dihydrouridine synthase: automated structure determination.	26143927
From cyclohydrolase to oxidoreductase: discovery of nitrile reductase activity in a common fold.	15767583
FTO expression is associated with the occurrence of gastric cancer and prognosis.	28849183
FTO expression is associated with the occurrence of gastric cancer and prognosis.	28849183
FTO haplotyping underlines high obesity risk for European populations.	30871540
FTO is involved in Alzheimer's disease by targeting TSC1-mTOR-Tau signaling.	29501742
FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N(6)-Methyladenosine RNADemethylase.	28017614
FTO regulates the chemo-radiotherapy resistance of cervical squamous cell carcinoma (CSCC) by targeting β-catenin through mRNA demethylation.	29315835
FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis.	25412662
FTO-mediated formation of N(6)-hydroxymethyladenosine and N(6)-formyladenosine in mammalian RNA.	23653210
Function and detection of 5-methylcytosine in eukaryotic RNA.	22122054
Functional analysis of mRNA scavenger decapping enzymes.	15273322
Functional and Structural Impact of Target Uridine Substitutions on the H/ACA Ribonucleoprotein Particle Pseudouridine Synthase	20575532
Functional categorization of the conserved basic amino acid residues in TrmH (tRNA (Gm18) methyltransferase) enzymes.	16963456
Functional characterization of the eukaryotic cysteine desulfurase Nfs1p from Saccharomyces cerevisiae.	15220327
Functional characterization of the mammalian mRNA decapping enzyme hDcp2.	12923261
Functional characterization of the YmcB and YqeV tRNA methylthiotransferases of Bacillus subtilis.	20472640
Functional diversity of the rhodanese homology domain: the Escherichia coli ybbB gene encodes a selenophosphate-dependent tRNA 2-selenouridine synthase.	14594807
Functional effect of deletion and mutation of the Escherichia coli ribosomal RNA and tRNA pseudouridine synthase RluA.	10383384
Functional homology between yeast piD261/Bud32 and human PRPK: both phosphorylate p53 and PRPK partially complements piD261/Bud32 deficiency.	12914926
Functional Implications for a Prototypical K-Turn Binding Protein from Structural and Dynamical Studies of 15.5K	18044964
Functional interaction of a novel 15.5kD [U4/U6.U5] tri-snRNP protein with the 5' stem-loop of U4 snRNA.	10545122
Functional link between the mammalian exosome and mRNA decapping.	11747811
Functional organization of box C/D RNA-guided RNA methyltransferase.	32297938
Functional promiscuity of the COG0720 family.	21999246
Functional redundancy of Spb1p and a snR52-dependent mechanism for the 2'-O-ribose methylation of a conserved rRNA position in yeast.	14636587
Functional requirement of a site-specific ribose methylation in ribosomal RNA.	8266080
Functional specialization of domains tandemly duplicated within 16S rRNA methyltransferase RsmC	17576679
Functional specialization of domains tandemly duplicated within 16S rRNA methyltransferase RsmC.	17576679
Functionally critical residues in the aminoglycoside resistance-associated methyltransferase RmtC play distinct roles in 30S substrate recognition.	31594862
Functionally critical residues in the aminoglycoside resistance-associated methyltransferase RmtC play distinct roles in 30S substrate recognition.	31594862
Functions and consequences of AID/APOBEC-mediated DNA and RNA deamination	35256818
Functions and Regulation of RNA Editing by ADAR Deaminases	20192758
Further insights into the tRNA modification process controlled by proteins MnmE and GidA of Escherichia coli.	17062623
GAR1 is an essential small nucleolar RNP protein required for pre-rRNA processing in yeast.	1531632
GCD14p, a repressor of GCN4 translation, cooperates with Gcd10p and Lhp1p in the maturation of initiator methionyl-tRNA in Saccharomyces cerevisiae.	10330157
Gcn4 misregulation reveals a direct role for the evolutionary conserved EKC/KEOPS in the t6A modification of tRNAs.	21459853
Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis.	26640150
Genetic alterations of mA regulators predict poorer survival in acute myeloid leukemia.	28153030
Genetic analysis identifies a function for the queC (ybaX) gene product at an initial step in the queuosine biosynthetic pathway in Escherichia coli.	16199558
Genetic and biochemical analysis of yeast and human cap trimethylguanosine synthase: functional overlap of 2,2,7-trimethylguanosine caps, small nuclear ribonucleoprotein components, pre-mRNA splicing factors, and RNA decay pathways.	18775984
Genetic associations and regulation of expression indicate an independent role for14q32 snoRNAs in human cardiovascular disease.	30544252
Genetic dissection of synthesis and function of modified nucleosides in bacterial transfer RNA.	7538683
Genetic interactions show the importance of rRNA modification machinery for the role of Rps15p during ribosome biogenesis in S. cerevisiae.	20454621
Genetic mapping and cloning of the gene (trmC) responsible for the synthesis of tRNA (mnm5s2U)methyltransferase in Escherichia coli K12.	6387395
Genetic variants in the Fat and Obesity Associated (FTO) gene and risk ofAlzheimer's disease.	23251365
Genome-wide association scan shows genetic variants in the FTO gene are associatedwith obesity-related traits.	17658951
Germline copy number variation in the YTHDC2 gene: does it have a role in finding a novel potential molecular target involved in pancreatic adenocarcinoma susceptibility?	24834797
Germline NPM1 mutations lead to altered rRNA 2'-O-methylation and cause dyskeratosis congenita.	31570891
Giardia lamblia RNA cap guanine-N2 methyltransferase (Tgs2).	16046409
Global analysis of A-to-I RNA editing reveals association with common disease variants.	29527417
Glu-Q-tRNA(Asp) synthetase coded by the yadB gene, a new paralog of aminoacyl-tRNA synthetase that glutamylates tRNA(Asp) anticodon.	16164993
Glycosidic bond conformation preference plays a pivotal role in catalysis of RNA pseudouridylation: a combined simulation and structural study.	20615421
Harnessing human ADAR2 for RNA repair - Recoding a PINK1 mutation rescues mitophagy.	27907896
HBXIP-elevated methyltransferase METTL3 promotes the progression of breast cancervia inhibiting tumor suppressor let-7g.	29174803
Helicase of Type 2 Porcine Reproductive and Respiratory Syndrome Virus Strain HV Reveals a Unique Structure.	32075207
HEN1 recognizes 21-24 nt small RNA duplexes and deposits a methyl group onto the 2' OH of the 3' terminal nucleotide.	16449203
High precision NMR structure of YhhP, a novel Escherichia coli protein implicated in cell division.	11080457
High precision NMR structure of YhhP, a novel Escherichia coli protein implicated in cell division.	11080457
High tRNA Transferase NSUN2 Gene Expression is Associated with Poor Prognosis inHead and Neck Squamous Carcinoma.	29775108
High-resolution structure of eukaryotic Fibrillarin interacting with Nop56 amino-terminal domain.	33483369
High-resolution structures of the SARS-CoV-2 2'- O -methyltransferase reveal strategies for structure-based inhibitor design.	32994211
High-resolution structures of the SARS-CoV-2 2'- O -methyltransferase reveal strategies for structure-based inhibitor design.	32994211
High-resolution structures of the SARS-CoV-2 2'--methyltransferase reveal strategies for structure-based inhibitor design.	32994211
hLARP7 C-terminal domain contains an xRRM that binds the 3' hairpin of 7SK RNA.	27679474
HNRNPA2/B1 is upregulated in endocrine-resistant LCC9 breast cancer cells and alters the miRNA transcriptome when overexpressed in MCF-7 cells.	31263129
How U38, 39, and 40 of many tRNAs become the targets for pseudouridylation by TruA.	17466622
How U38, 39, and 40 of Many tRNAs Become the Targets for Pseudouridylation by TruA.	17466622
How U38, 39, and 40 of Many tRNAs Become the Targets for Pseudouridylation by TruA.	17466622
Human Abh3 Structure and Key Residues for Oxidative Demethylation to Reverse DNA/RNA Damage.	16858410
Human AlkB homolog ABH8 Is a tRNA methyltransferase required for wobble uridine modification and DNA damage survival.	20308323
Human AlkB homologue 5 is a nuclear 2-oxoglutarate dependent oxygenase and a direct target of hypoxia-inducible factor 1alpha (HIF-1alpha).	21264265
Human ALKBH3-induced m(1)A demethylation increases the CSF-1 mRNA stability inbreast and ovarian cancer cells.	30342176
Human BLCAP transcript: new editing events in normal andcancerous tissues	19908260
Human cells have a limited set of tRNA anticodon loop substrates of the tRNA isopentenyltransferase TRIT1 tumor suppressor	24126054
Human Dcp2: a catalytically active mRNA decapping enzyme located in specific cytoplasmic structures.	12486012
Human fibrillarin forms a sub-complex with splicing factor 2-associated p32, protein arginine methyltransferases, and tubulins alpha 3 and beta 1 that is independent of its association with preribosomal ribonucleoprotein complexes.	14583623
Human mitochondrial diseases caused by lack of taurine modification in mitochondrial tRNAs.	21957023
Human mitochondrial transcription factor B1 methylates ribosomal RNA at a conserved stem-loop.	12496758
Human mitochondrial tRNAs: biogenesis, function, structural aspects, and diseases.	21910628
Human mRNA cap methyltransferase: alternative nuclear localization signal motifs ensure nuclear localization required for viability.	15767670
Human NAT10 is an ATP-dependent RNA acetyltransferase responsible for N4-acetylcytidine formation in 18S rRNA.	25411247
Human RNA Methyltransferase BCDIN3D Regulates MicroRNA Processing.	23063121
Human TRMT1 catalyzes m2G or m22G formation on tRNAs in a substrate-dependent manner	37204604
Human TRMU encoding the mitochondrial 5-methylaminomethyl-2-thiouridylate-methyltransferase is a putative nuclear modifier gene for the phenotypic expression of the deafness-associated 12S rRNA mutations.	16513084
Hydroxylation of a conserved tRNA modification establishes non-universal genetic code in echinoderm mitochondria.	28783151
Hypermethylated-capped selenoprotein mRNAs in mammals.	25013170
Hypermethylation of 28S ribosomal RNA in β-thalassemia trait carriers.	27765567
Hypermethylation of the cap structure of both yeast snRNAs and snoRNAs requires a conserved methyltransferase that is localized to the nucleolus.	11983179
Hypermethylation of yeast telomerase RNA by the snRNA and snoRNA methyltransferase Tgs1.	18840651
Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m⁶A-demethylation of NANOG mRNA.	27001847
Identification and characterization of a human tRNA-specific adenosine deaminase related to the ADAR family of pre-mRNA editing enzymes.	10430867
Identification and characterization of RsmE, the founding member of a new RNA base methyltransferase family.	16431987
Identification and characterization of the Thermus thermophilus 5-methylcytidine (m5C) methyltransferase modifying 23 S ribosomal RNA (rRNA) base C1942.	22711535
Identification and Characterization of the Thermus thermophilus 5-Methylcytidine (m5C) Methyltransferase Modifying 23 S Ribosomal RNA (rRNA) Base C1942.	22711535
Identification and characterization of the tRNA:Psi 31-synthase (Pus6p) of Saccharomyces cerevisiae.	11406626
Identification and characterization of tRNA (Gm18) methyltransferase from Thermus thermophilus HB8: domain structure and conserved amino acid sequence motifs.	11918670
Identification and codon reading properties of 5-cyanomethyl uridine, a new modified nucleoside found in the anticodon wobble position of mutant haloarchaeal isoleucine tRNAs.	24344322
Identification and site of action of the remaining four putative pseudouridine synthases in Escherichia coli.	11720289
Identification of 2-methylthio cyclic N6-threonylcarbamoyladenosine (ms2ct6A) as a novel RNA modification at position 37 of tRNAs	5389704
Identification of 5-hydroxycytidine at position 2501 concludes characterization of modified nucleotides in E. coli 23S rRNA.	21723290
Identification of 8-methyladenosine as the modification catalyzed by the radical SAM methyltransferase Cfr that confers antibiotic resistance in bacteria.	19144912
Identification of a bifunctional enzyme MnmC involved in the biosynthesis of a hypermodified uridine in the wobble position of tRNA.	15247431
Identification of a gene involved in the generation of 4-thiouridine in tRNA.	9592144
Identification of a novel 5-aminomethyl-2-thiouridine methyltransferase in tRNA modification.	36762482
Identification of a novel gene encoding a flavin-dependent tRNA:m5U methyltransferase in bacteria--evolutionary implications.	16027442
Identification of a novel methyltransferase, Bmt2, responsible for the N-1-methyl-adenosine base modification of 25S rRNA in Saccharomyces cerevisiae	23558746
Identification of a novel tRNA wobble uridine modifying activity in the biosynthesis of 5-methoxyuridine.	29982645
Identification of a novel tRNA wobble uridine modifying activity in the biosynthesis of 5-methoxyuridine.	29982645
Identification of a quality-control mechanism for mRNA 5'-end capping.	20802481
Identification of a tRNA isopentenyltransferase gene from Arabidopsis thaliana.	11999372
Identification of Aquifex aeolicus tRNA (m2(2G26) methyltransferase gene.	12903189
Identification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cells.	14660579
Identification of CGI-121, a novel PRPK (p53-related protein kinase)-binding protein.	12659830
Identification of determinants for tRNA substrate recognition by Escherichia coli C/U34 2'-O-methyltransferase.	26106808
Identification of determinants in the protein partners aCBF5 and aNOP10 necessary for the tRNA:Psi55-synthase and RNA-guided RNA:Psi-synthase activities.	17704128
Identification of entacapone as a chemical inhibitor of FTO mediating metabolic regulation through FOXO1	30996080
Identification of Escherichia coli m2G methyltransferases: I. the ycbY gene encodes a methyltransferase specific for G2445 of the 23 S rRNA.	17010378
Identification of Escherichia coli m2G methyltransferases: II. The ygjO gene encodes a methyltransferase specific for G1835 of the 23 S rRNA.	17010380
Identification of eukaryotic and prokaryotic methylthiotransferase for biosynthesis of 2-methylthio-N6-threonylcarbamoyladenosine in tRNA.	20584901
Identification of factors required for m(6) A mRNA methylation in Arabidopsis reveals a role for the conserved E3 ubiquitin ligase HAKAI.	28503769
Identification of factors required for m6 A mRNA methylation in Arabidopsis reveals a role for the conserved E3 ubiquitin ligase HAKAI	28503769
Identification of factors required for m6 A mRNA methylation in Arabidopsis reveals a role for the conserved E3 ubiquitin ligase HAKAI	28503769
Identification of four genes necessary for biosynthesis of the modified nucleoside queuosine.	14660578
Identification of human tRNA:m5C methyltransferase catalysing intron-dependent m5C formation in the first position of the anticodon of the pre-tRNA Leu (CAA).	17071714
Identification of novel methyltransferases, Bmt5 and Bmt6, responsible for the m3U methylations of 25S rRNA in Saccharomyces cerevisiae.	24335083
Identification of pseudouridine methyltransferase in Escherichia coli.	18755836
Identification of the 16S rRNA m5C967 methyltransferase from Escherichia coli.	10194318
Identification of the chloroplast adenosine-to-inosine tRNA editing enzyme.	19460869
Identification of the enzyme responsible for N1-methylation of pseudouridine 54 in archaeal tRNAs.	22274954
Identification of the mAm Methyltransferase PCIF1 Reveals the Location and Functions of mAm in the Transcriptome.	31279658
Identification of the methyltransferase targeting C2499 in Deinococcus radiodurans 23S ribosomal RNA.	26590840
Identification of the miaB gene, involved in methylthiolation of isopentenylated A37 derivatives in the tRNA of Salmonella typhimurium and Escherichia coli.	10572129
Identification of the rrmA gene encoding the 23S rRNA m1G745 methyltransferase in Escherichia coli and characterization of an m1G745-deficient mutant.	9440525
Identification of the RsmG methyltransferase target as 16S rRNA nucleotide G527 and characterization of Bacillus subtilis rsmG mutants.	17573471
Identification of the Saccharomyces cerevisiae RNA:pseudouridine synthase responsible for formation of psi(2819) in 21S mitochondrial ribosomal RNA.	10756195
Identification of the TRM2 gene encoding the tRNA(m5U54)methyltransferase of Saccharomyces cerevisiae.	10864043
Identification of the tRNA-dihydrouridine synthase family.	11983710
Identification of the yeast gene encoding the tRNA m1G methyltransferase responsible for modification at position 9.	12702816
Identification of two Escherichia coli pseudouridine synthases that show multisite specificity for 23S RNA.	9843401
Identification of two tRNA thiolation genes required for cell growth at extremely high temperatures.	16547008
Identification of yeast tRNA Um(44) 2'-O-methyltransferase (Trm44) and demonstration of a Trm44 role in sustaining levels of specific tRNA(Ser) species.	18025252
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase.	34198328
Identifying the methyltransferases for m(5)U747 and m(5)U1939 in 23S rRNA using MALDI mass spectrometry.	12907714
Implications of a functional large ribosomal RNA with only three modified nucleotides.	7541254
In Human Pseudouridine Synthase 1 (hPus1), a C-Terminal Helical Insert Blocks tRNA from Binding in the Same Orientation as in the Pus1 Bacterial Homologue TruA, Consistent with Their Different Target Selectivities.	23707380
In Human Pseudouridine Synthase 1 (hPus1), a C-Terminal Helical Insert Blocks tRNA from Binding in the Same Orientation as in the Pus1 Bacterial Homologue TruA, Consistent with Their Different Target Selectivities.	23707380
In silico analysis of the tRNA:m1A58 methyltransferase family: homology-based fold prediction and identification of new members from Eubacteria and Archaea.	11684083
In vitro synthesis of selenocysteinyl-tRNA(UCA) from seryl-tRNA(UCA): involvement and characterization of the selD gene product.	2405383
Inactivation of KsgA, a 16S rRNA methyltransferase, causes vigorous emergence of mutants with high-level kasugamycin resistance.	19001112
Inactivation of the Fto gene protects from obesity.	19234441
Increased adenosine-to-inosine RNA editing in rheumatoid arthritis	31493964
Increased N6-methyladenosine causes infertility is associated with FTO expression.	29384212
Induction of sporulation in Saccharomyces cerevisiae leads to the formation of N6-methyladenosine in mRNA: a potential mechanism for the activity of the IME4 gene.	12384598
Influence of phylogeny on posttranscriptional modification of rRNA in thermophilic prokaryotes: the complete modification map of 16S rRNA of Thermus thermophilus.	16605256
Influence of temperature on tRNA modification in archaea: Methanococcoides burtonii (optimum growth temperature [Topt], 23 degrees C) and Stetteria hydrogenophila (Topt, 95 degrees C).	12949100
Initiator tRNAs from archaebacteria show common unique sequence characteristics.	6178978
Inositol hexakisphosphate is bound in the ADAR2 core and required for RNA editing.	16141067
Insights into catalysis by a knotted TrmD tRNA methyltransferase.	14583191
Insights into Catalysis by a Knotted TrmD tRNA Methyltransferase.	14583191
Insights into DNA substrate selection by APOBEC3G from structural, biochemical, and functional studies.	29596531
Insights into folate/FAD-dependent tRNA methyltransferase mechanism: role of two highly conserved cysteines in catalysis.	21846722
Insights into molecular plasticity in protein complexes from Trm9-Trm112 tRNA modifying enzyme crystal structure.	26438534
Insights into molecular plasticity in protein complexes from Trm9-Trm112 tRNA modifying enzyme crystal structure.	26438534
Insights into the hyperthermostability and unusual region-specificity of archaeal Pyrococcus abyssi tRNA m1A57/58 methyltransferase.	20483913
Insights into the hyperthermostability and unusual region-specificity of archaeal Pyrococcus abyssi tRNA m1A57/58 methyltransferase.	20483913
Insights into the hyperthermostability and unusual region-specificity of archaeal Pyrococcus abyssi tRNA m1A57/58 methyltransferase.	20483913
Insights into the structure, function and evolution of the radical-SAM 23S rRNA methyltransferase Cfr that confers antibiotic resistance in bacteria.	20007606
Insights into the structure, mechanism, and regulation of scavenger mRNA decapping activity	15068804
Insights into the structure, mechanism, and regulation of scavenger mRNA decapping activity	15068804
Insights into the structure, mechanism, and regulation of scavenger mRNA decapping activity.	15068804
Interaction mode between catalytic and regulatory subunits in glucosidase II involved in ER glycoprotein quality control	27576940
Interaction of the tylosin-resistance methyltransferase RlmA II at its rRNA target differs from the orthologue RlmA I.	18406425
Intrinsic resistance to aminoglycosides in Enterococcus faecium is conferred by the 16S rRNA m5C1404-specific methyltransferase EfmM.	21159796
Introduction of hypermodified nucleotides in RNA.	15333904
Intron-dependent formation of pseudouridines in the anticodon of Saccharomyces cerevisiae minor tRNA(Ile).	7925304
Iron-sulfur cluster assembly: characterization of IscA and evidence for a specific and functional complex with ferredoxin.	11319236
Iron-sulfur cluster biosynthesis in bacteria: Mechanisms of cluster assembly and transfer.	18191630
IscS is a sulfurtransferase for the in vitro biosynthesis of 4-thiouridine in Escherichia coli tRNA.	10600118
Isd11p protein activates the mitochondrial cysteine desulfurase Nfs1p protein.	21908622
Isolation and characterization of a human cDNA for mRNA 5'-capping enzyme.	9512541
Isolation and characterization of MOD5, a gene required for isopentenylation of cytoplasmic and mitochondrial tRNAs of Saccharomyces cerevisiae.	3031456
Isolation and characterization of SUA5, a novel gene required for normal growth in Saccharomyces cerevisiae.	1325384
Isolation and characterization of the human tRNA-(N1G37) methyltransferase (TRM5) and comparison to the Escherichia coli TrmD protein.	15248782
Isolation and characterization of the TRM1 locus, a gene essential for the N2,N2-dimethylguanosine modification of both mitochondrial and cytoplasmic tRNA in Saccharomyces cerevisiae.	2426253
Isolation and characterization of the yeast mRNA capping enzyme beta subunit gene encoding RNA 5'-triphosphatase, which is essential for cell viability.	9345280
Isolation and sequencing of NOP1. A yeast gene encoding a nucleolar protein homologous to a human autoimmune antigen.	2298745
Isolation of 5-hydroxyuridine (iso-barbituridine) from yeast ribonucleic acids.	5957714
Isolation of temperature-sensitive mutants for mRNA capping enzyme in Saccharomyces cerevisiae.	7500935
Isolation of the gene (miaE) encoding the hydroxylase involved in the synthesis of 2-methylthio-cis-ribozeatin in tRNA of Salmonella typhimurium and characterization of mutants.	8253666
KIAA1429 contributes to liver cancer progression through N6-methyladenosine-dependent post-transcriptional modification of GATA3.	31856849
KIAA1429 regulates the migration and invasion of hepatocellular carcinoma by altering m6A modification of ID2 mRNA.	31118692
Kinetic and functional analysis of the small RNA methyltransferase HEN1: the catalytic domain is essential for preferential modification of duplex RNA.	20705645
Kissing G domains of MnmE monitored by X-ray crystallography and pulse electron paramagnetic resonance spectroscopy	19806182
Kissing G domains of MnmE monitored by X-ray crystallography and pulse electron paramagnetic resonance spectroscopy.	19806182
KMT9 monomethylates histone H4 lysine 12 and controls proliferation of prostate cancer cells.	31061526
Known bioactive small molecules probe the function of a widely conserved but enigmatic bacterial ATPase, YjeE.	19101473
Lack of pseudouridine 38/39 in the anticodon arm of yeast cytoplasmic tRNA decreases in vivo recoding efficiency.	12058040
LC/MS analysis and deep sequencing reveal the accurate RNA composition in the HIV-1 virion.	31213632
LC/MS analysis of cellular RNA reveals NAD-linked RNA.	19820715
Letter: The structure of Q* nucleoside isolated from rabbit liver transfer ribonucleic acid.	950430
Life without the essential bacterial tRNA Ile2-lysidine synthetase TilS: a case of tRNA gene recruitment in Bacillus subtilis.	21435031
Ligand-mediated anticodon conformational changes occur during tRNA methylation by a TrmD methyltransferase.	15850396
Local cerebral glucose consumption during ethanol withdrawal in the rat: effects of single and multiple episodes and previous convulsive seizures.	3401759
Loss of 5-methylcytosine alters the biogenesis of vault-derived small RNAs to coordinate epidermal differentiation.	31186410
Loss of a conserved 7-methylguanosine modification in 16S rRNA confers low-level streptomycin resistance in bacteria.	17238915
Loss of a Conserved tRNA Anticodon Modification Perturbs Plant Immunity.	26492405
Loss of a universal tRNA feature.	17172343
Loss of Ftsj1 perturbs codon-specific translation efficiency in the brain and is associated with X-linked intellectual disability.	33771871
Loss of the ribosomal RNA methyltransferase NSUN5 impairs global protein synthesis and normal growth	31722427
m(6)A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells bySustaining FOXM1 Expression and Cell Proliferation Program.	28344040
m(6)A demethylase FTO facilitates tumor progression in lung squamous cell carcinomaby regulating MZF1 expression.	29842885
m(6)A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of GlioblastomaStem Cells.	28297667
m1A Regulated Genes Modulate PI3K/AKT/mTOR and ErbB Pathways in GastrointestinalCancer.	31352195
m6A modification of U6 snRNA modulates usage of two major classes of pre-mRNA 5' splice site	36409063
M6A-mediated upregulation of LINC00958 increases lipogenesis and acts as a nanotherapeutic target in hepatocellular carcinoma.	31915027
mA demethylase ALKBH5 inhibits pancreatic cancer tumorigenesis by decreasing WIF-1 RNA methylation and mediating Wnt signaling.	31906946
mA methyltransferase METTL3 suppresses colorectal cancer proliferation and migration through p38/ERK pathways.	31239708
mA modification suppresses ocular melanoma through modulating HINT2 mRNA translation.	31722709
mA mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade.	31239444
mA mRNA methylation initiated by METTL3 directly promotes YAP translation and increases YAP activity by regulating the MALAT1-miR-1914-3p-YAP axis to induce NSCLC drug resistance and metastasis.	31818312
mA mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer.	30154548
mA mRNA Methylation Regulates Human β-Cell Biology in Physiological States and in Type 2 Diabetes.	31867565
mA-induced lncRNA RP11 triggers the dissemination of colorectal cancer cells via upregulation of Zeb1.	30979372
Major Reorientation of tRNA Substrates Defines Specificity of Dihydrouridine Synthases.	25902496
Major reorientation of tRNA substrates defines specificity of dihydrouridine synthases.	25902496
Mammalian ALKBH8 possesses tRNA methyltransferase activity required for the biogenesis of multiple wobble uridine modifications implicated in translational decoding.	20123966
Mammalian nuclear TRUB1, mitochondrial TRUB2, and cytoplasmic PUS10 produce conserved pseudouridine 55 in different sets of tRNA.	33023933
Mammalian Nudix proteins cleave nucleotide metabolite caps on RNAs.	32432673
Mechanism and substrate specificity of tRNA-guanine transglycosylases (TGTs): tRNA-modifying enzymes from the three different kingdoms of life share a common catalytic mechanism.	16206323
Mechanism of 5' splice site transfer for human spliceosome activation.	30975767
Mechanism of dihydrouridine synthase 2 from yeast and the importance of modifications for efficient tRNA reduction.	19139092
Mechanism of mitoribosomal small subunit biogenesis and preinitiation.	35676484
Mechanism of N-methylation by the tRNA m1G37 methyltransferase Trm5.	20980671
Mechanism of N6-threonylcarbamoyladenonsine (t(6)A) biosynthesis: isolation and characterization of the intermediate threonylcarbamoyl-AMP.	23072323
Mechanisms of substrate recognition and N6-methyladenosine demethylation revealed by crystal structures of ALKBH5-RNA complexes.	35333330
Mechanistic characterization of the sulfur-relay system for eukaryotic 2-thiouridine biogenesis at tRNA wobble positions.	19151091
Mechanistic insight into the ribosome biogenesis functions of the ancient protein KsgA.	18990185
Mechanistic insights into m6A modification of U6 snRNA by human METTL16.	32266935
Mechanistic insights into small RNA recognition and modification by the HEN1 methyltransferase.	23621770
Mechanistic insights into sulfur relay by multiple sulfur mediators involved in thiouridine biosynthesis at tRNA wobble positions.	16387657
Mechanistic investigations of the pseudouridine synthase RluA using RNA containing 5-fluorouridine.	17002302
Mechanistic studies of Bacillus subtilis QueF, the nitrile oxidoreductase involved in queuosine biosynthesis.	17929836
Meclofenamic acid selectively inhibits FTO demethylation of m6A over ALKBH5.	25452335
Messenger RNA guanylyltransferase from Saccharomyces cerevisiae. Large scale purification, subunit functions, and subcellular localization.	3029058
Methylaminedeprotectionprovidesincreasedyield of oligoribonucleotides	10.1016/0040-4039(95)01953-F
Methylated 23S rRNA nucleotide m2G1835 of Escherichia coli ribosome facilitates subunit association.	21237242
Methylation as a crucial step in plant microRNA biogenesis.	15705854
Methylation by NSun2 represses the levels and function of microRNA 125b.	25047833
Methylation of 12S rRNA is necessary for in vivo stability of the small subunit of the mammalian mitochondrial ribosome.	19356719
Methylation of 23S rRNA nucleotide G745 is a secondary function of the RlmAI methyltransferase.	15388872
Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan.	25635753
Methylation of Structured RNA by the m6A Writer METTL16 Is Essential for Mouse Embryonic Development.	30197299
Methylation of Structured RNA by the m6A Writer METTL16 Is Essential for Mouse Embryonic Development.	30197299
Methylation of tRNAAsp by the DNA methyltransferase homolog Dnmt2.	16424344
Methylation protects miRNAs and siRNAs from a 3'-end uridylation activity in Arabidopsis.	16111943
Methyltransferase that modifies guanine 966 of the 16 S rRNA: functional identification and tertiary structure.	17189261
Methyltransferase that modifies guanine 966 of the 16 S rRNA: functional identification and tertiary structure.	17189261
Mettl14 inhibits bladder TIC self-renewal and bladder tumorigenesis through N-methyladenosine of Notch1.	31760940
METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and PromotesLeukemogenesis via mRNA m(6)A Modification.	29290617
METTL14 Suppresses CRC Progression via Regulating N6-Methyladenosine-DependentPrimary miR-375 Processing.	31839484
METTL14 suppresses the metastatic potential of hepatocellular carcinoma by modulating N -methyladenosine-dependent primary MicroRNA processing.	27774652
METTL15 interacts with the assembly intermediate of murine mitochondrial small ribosomal subunit to form m4C840 12S rRNA residue.	32573735
METTL15 introduces N4-methylcytidine into human mitochondrial 12S rRNA and is required for mitoribosome biogenesis.	31665743
METTL3 and ALKBH5 oppositely regulate mA modification of mRNA, which dictates the fate of hypoxia/reoxygenation-treated cardiomyocytes.	30870073
METTL3 facilitates tumor progression via an mA-IGF2BP2-dependent mechanism in colorectal carcinoma.	31230592
METTL3 Inhibitors for Epitranscriptomic Modulation of Cellular Processes.	34237194
METTL3 promote tumor proliferation of bladder cancer by accelerating pri-miR221/222 maturation in m6A-dependent manner.	31228940
METTL3 Promotes the Proliferation and Mobility of Gastric Cancer Cells	30886897
METTL3 Promotes the Proliferation and Mobility of Gastric Cancer Cells.	30886897
Mettl3-mediated mA RNA methylation regulates the fate of bone marrow mesenchymal stem cells and osteoporosis.	30429466
METTL4 is an snRNA mAm methyltransferase that regulates RNA splicing.	31913360
MiaB protein from Thermotoga maritima. Characterization of an extremely thermophilic tRNA-methylthiotransferase.	12766153
MiaB protein is a bifunctional radical-S-adenosylmethionine enzyme involved in thiolation and methylation of tRNA.	15339930
MiaB, a bifunctional radical-S-adenosylmethionine enzyme involved in the thiolation and methylation of tRNA, contains two essential [4Fe-4S] clusters.	17407324
MicroRNA-145 Modulates -Methyladenosine Levels by Targeting the 3'-Untranslated mRNA Region of the -Methyladenosine Binding YTH Domain Family 2 Protein.	28104805
MiR-33a suppresses proliferation of NSCLC cells via targeting METTL3 mRNA.	27856248
Missense mutation in pseudouridine synthase 1 (PUS1) causes mitochondrial myopathyand sideroblastic anemia (MLASA).	15108122
Mitochondria-specific RNA-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial tRNAs. Implications for the molecular pathogenesis of human mitochondrial diseases.	15509579
Mitochondrial 16S rRNA Is Methylated by tRNA Methyltransferase TRMT61B in All Vertebrates.	27631568
Mitochondrial myopathy and sideroblastic anemia (MLASA): missense mutation in the pseudouridine synthase 1 (PUS1) gene is associated with the loss of tRNA pseudouridylation.	15772074
Mitochondrial tRNA import in Toxoplasma gondii.	15280394
MnmA and IscS are required for in vitro 2-thiouridine biosynthesis in Escherichia coli.	12549933
Modifications Modulate Anticodon Loop Dynamics and Codon Recognition of E. coli tRNA(Arg1,2).	22240457
Modulation of microRNA editing, expression and processing by ADAR2 deaminase in glioblastoma.	25582055
Molecular architecture of the 90S small subunit pre-ribosome	28244370
Molecular architecture of the 90S small subunit pre-ribosome.	28244370
Molecular architecture of the human U4/U6.U5 tri-snRNP.	26912367
Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1	29379020
Molecular basis for transfer RNA recognition by the double-stranded RNA-binding domain of human dihydrouridine synthase 2.	30605527
Molecular basis of box C/D RNA-protein interactions; cocrystal structure of archaeal L7Ae and a box C/D RNA.	15130473
Molecular Basis of Box C/D RNA-Protein Interactions; Cocrystal Structure of Archaeal L7Ae and a Box C/D RNA.	15130473
Molecular basis of tRNA recognition by the Elongator complex.	31309145
Molecular biology. Internal mRNA methylation finally finds functions.	24626918
Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editing	7972084
Molecular cloning of the Escherichia coli miaA gene involved in the formation of delta 2-isopentenyl adenosine in tRNA.	3045085
Molecular determinants of dihydrouridine synthase activity.	16962594
Molecular evolution of dihydrouridine synthases.	22741570
Molecular Interactions of a DNA Modifying Enzyme APOBEC3F Catalytic Domain with a Single-Stranded DNA.	29191651
Molecular phylogenetics and comparative modeling of HEN1, a methyltransferase involved in plant microRNA biogenesis.	16433904
Molecular phylogenetics of the RrmJ/fibrillarin superfamily of ribose 2'-O-methyltransferases.	12527203
Molecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA.	24717845
Molecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA.	24717845
Molybdenum cofactor biosynthesis in humans: identification of a persulfide group in the rhodanese-like domain of MOCS3 by mass spectrometry.	15910006
Monomeric tRNA (m(7)G46) methyltransferase from Escherichia coli presents a novel structure at the function-essential insertion	19373903
Monomeric tRNA (m(7)G46) methyltransferase from Escherichia coli presents a novel structure at the function-essential insertion	19373903
Mouse Trmt2B protein is a dual specific mitochondrial metyltransferase responsible for mU formation in both tRNA and rRNA.	31736397
MRM2 and MRM3 are involved in biogenesis of the large subunit of the mitochondrial ribosome.	25009282
MRM2 encodes a novel yeast mitochondrial 21S rRNA methyltransferase.	11867542
mRNA capping enzyme. Isolation and characterization of the gene encoding mRNA guanylytransferase subunit from Saccharomyces cerevisiae.	1315757
mRNA circularization by METTL3-eIF3h enhances translation and promotes oncogenesis.	30232453
mRNA:guanine-N7 cap methyltransferases: identification of novel members of the family, evolutionary analysis, homology modeling, and analysis of sequence-structure-function relationships.	11472630
MSS1, a nuclear-encoded mitochondrial GTPase involved in the expression of COX1 subunit of cytochrome c oxidase.	8392589
MTA is an Arabidopsis messenger RNA adenosine methylase and interacts with a homolog of a sex-specific splicing factor.	18505803
MTERF4 regulates translation by targeting the methyltransferase NSUN4 to the mammalian mitochondrial ribosome.	21531335
MTO1 codes for a mitochondrial protein required for respiration in paromomycin-resistant mutants of Saccharomyces cerevisiae.	9774408
mU54 tRNA Hypomodification by Lack of TRMT2A Drives the Generation of tRNA-Derived Small RNAs.	33799331
Multi-site-specific 16S rRNA methyltransferase RsmF from Thermus thermophilus.	20558545
Multi-site-specific 16S rRNA methyltransferase RsmF from Thermus thermophilus.	20558545
Multi-site-specific 16S rRNA methyltransferase RsmF from Thermus thermophilus.	20558545
Multi-site-specific 16S rRNA methyltransferase RsmF from Thermus thermophilus.	20558545
Multiple enzymatic activities associated with severe acute respiratory syndrome coronavirus helicase.	15140959
Multiple mRNA decapping enzymes in mammalian cells.	21070968
Multisite-specific archaeosine tRNA-guanine transglycosylase (ArcTGT) from Thermoplasma acidophilum, a thermo-acidophilic archaeon.	26721388
Multisite-specific tRNA:m5C-methyltransferase (Trm4) in yeast Saccharomyces cerevisiae: identification of the gene and substrate specificity of the enzyme.	10445884
Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase reveal aspartate 102 as the active site nucleophile.	8961936
Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase to elucidate the role of serine 103 for enzymatic activity.	10413112
Mutagenesis of the modified bases, m(5)U1939 and psi2504, in Escherichia coli 23S rRNA.	20067766
Mutagenesis of the peptidyltransferase center of 23S rRNA: the invariant U2449 is dispensable.	11160893
Mutation in TRMU related to transfer RNA modification modulates the phenotypic expression of the deafness-associated mitochondrial 12S ribosomal RNA mutations.	16826519
Mutation in WDR4 impairs tRNA m(7)G46 methylation and causes a distinct form of microcephalic primordial dwarfism.	26416026
Mutational analysis of the Saccharomyces cerevisiae ABD1 gene: cap methyltransferase activity is essential for cell growth.	8552073
Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature.	23001123
Mutations in MTO2 related to tRNA modification impair mitochondrial gene expression and protein synthesis in the presence of a paromomycin resistance mutation in mitochondrial 15 S rRNA.	15944150
Mutations in rsmG, encoding a 16S rRNA methyltransferase, result in low-level streptomycin resistance and antibiotic overproduction in Streptomyces coelicolor A3(2).	17384192
Mutations in the FTSJ1 gene coding for a novel S-adenosylmethionine-binding protein cause nonsyndromic X-linked mental retardation.	15162322
Mutations of the RNA-Specific Adenosine Deaminase Gene (DSRAD) Are Involved in Dyschromatosis Symmetrica Hereditaria	12916015
Mutually exclusive substrate selection strategy by human m3C RNA transferases METTL2A and METTL6.	34268557
Mycobacterium tuberculosis Rv2118c codes for a single-component homotetrameric m1A58 tRNA methyltransferase.	14960715
N(6)-methyladenosine ALKBH5 promotes non-small cell lung cancer progress byregulating TIMP3 stability.	31927006
N-Deoxyadenosine Methylation in Mammalian Mitochondrial DNA.	32183942
N-methyladenosine contributes to cellular phenotype in a genetically-defined model of breast cancer progression.	30131850
N1-methyladenosine profiling of long non-coding RNA in colorectal cancer.	34314547
N2-methylation of guanosine at position 10 in tRNA is catalyzed by a THUMP domain-containing, S-adenosylmethionine-dependent methyltransferase, conserved in Archaea and Eukaryota.	15210688
N6-Acetyladenosine: a new modified nucleoside from Methanopyrus kandleri tRNA.	15907485
N6-adenosine methylation in mRNA: substrate specificity and enzyme complexity.	7748945
N6-methyladenosine demethylase FTO suppresses clear cell renal cell carcinoma through a novel FTO-PGC-1α signalling axis.	30648791
N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO.	22002720
N6-methyladenosine induced miR-143-3p promotes the brain metastasis of lung cancer via regulation of VASH1.	31823788
N6-methyladenosine METTL3 promotes the breast cancer progression via targetingBcl-2.	31454538
N6-methyladenosine-related Genomic Targets are Altered in Breast Cancer Tissue and Associated with Poor Survival.	31632489
New and convenient protection system for pseudouridine, highly suitable for solid-phase oligoribonucleotide synthesis	10.1039/P19940003423
New bioinformatic tools for analysis of nucleotide modifications in eukaryotic rRNA.	17283215
New function of vitamin B12: cobamide-dependent reduction of epoxyqueuosine to queuosine in tRNAs of Escherichia coli and Salmonella typhimurium.	3129401
New structural insights reveal an expanded reaction cycle for inositol pyrophosphate hydrolysis by human DIPP1.	33475202
New structural insights reveal an expanded reaction cycle for inositol pyrophosphate hydrolysis by human DIPP1.	33475202
Nhp2p and Nop10p are essential for the function of H/ACA snoRNPs.	9843512
NMethyladenosine methyltransferase ZCCHC4 mediates ribosomal RNA methylation.	30531910
NMR structure of human restriction factor APOBEC3A reveals substrate binding and enzyme specificity.	23695684
NMR-based Structural Analysis of Threonylcarbamoyl-AMP Synthase and Its Substrate Interactions.	2MX1
Nop2p is required for pre-rRNA processing and 60S ribosome subunit synthesis in yeast.	8972218
Nop5p is a small nucleolar ribonucleoprotein component required for pre-18 S rRNA processing in yeast.	9632712
Novel long noncoding RNA NMR promotes tumor progression via NSUN2 and BPTF inesophageal squamous cell carcinoma.	29763634
Novel methyltransferase for modified uridine residues at the wobble position of tRNA.	14645538
Novel plasmid-mediated 16S rRNA m1A1408 methyltransferase, NpmA, found in a clinically isolated Escherichia coli strain resistant to structurally diverse aminoglycosides.	17875999
NSUN2 modified by SUMO-2/3 promotes gastric cancer progression and regulates mRNA m5C methylation.	34504059
NSUN3 and ABH1 modify the wobble position of mt-tRNAMet to expand codon recognition in mitochondrial translation.	27497299
NSUN3 methylase initiates 5-formylcytidine biogenesis in human mitochondrial tRNA(Met).	27214402
NSUN3-mediated mitochondrial tRNA 5-formylcytidine modification is essential for embryonic development and respiratory complexes in mice	36949224
NSUN4 is a dual function mitochondrial protein required for both methylation of 12S rRNA and coordination of mitoribosomal assembly.	24516400
NSUN6 is a human RNA methyltransferase that catalyzes formation of m5C72 in specific tRNAs.	26160102
Nuclear Magnetic Resonance Structure of the APOBEC3B Catalytic Domain: Structural Basis for Substrate Binding and DNA Deaminase Activity.	27163633
Nucleolar KKE/D repeat proteins Nop56p and Nop58p interact with Nop1p and are required for ribosome biogenesis.	9372940
Nucleolar maturation of the human small subunit processome.	34516797
Nucleotide sequence of nuclear 5.4 S RNA of mouse cells.	6202321
Nucleotide sequence of the erythromycin resistance gene of the conjugative transposon Tn1545.	2163525
Nucleotide sequence of tRNA(Thr1) of Escherichia coli and of the gene (thrV) that encodes it.	1380693
Nucleotide sequences encoding and promoting expression of three antibiotic resistance genes indigenous to Streptomyces.	2987648
N⁶-Methyladenosine Landscape of Glioma Stem-Like Cells: METTL3 Is Essential for the Expression of Actively Transcribed Genes and Sustenance of the Oncogenic Signaling.	30781903
N⁶-Methyladenosine Landscape of Glioma Stem-Like Cells: METTL3 Is Essential for theExpression of Actively Transcribed Genes and Sustenance of the Oncogenic Signaling	30781903
Oncogene c-Myc promotes epitranscriptome mA reader YTHDF1 expression in colorectal cancer.	29484125
Oncogene c-Myc promotes epitranscriptome mA reader YTHDF1 expression in colorectal cancer.	29484125
Over expression of a tRNA(Leu) isoacceptor changes charging pattern of leucine tRNAs and reveals new codon reading.	16236318
Overexpression of the thiostrepton-resistance gene from Streptomyces azureus in Escherichia coli and characterization of recognition sites of the 23S rRNA A1067 2'-methyltransferase in the guanosine triphosphatase center of 23S ribosomal RNA.	7925357
Overexpression of YTHDF1 is associated with poor prognosis in patients with hepatocellular carcinoma	29439311
Overexpression of YTHDF1 is associated with poor prognosis in patients withhepatocellular carcinoma.	29439311
Overexpression, crystallization and preliminary X-ray crystallographic analysis of Pseudomonas aeruginosa MnmE, a GTPase involved in tRNA modification.	20693664
Overview of distinct 5-methylcytosine profiles of messenger RNA in human hepatocellular carcinoma and paired adjacent non-tumor tissues.	32571340
p53 acts as a safeguard of translational control by regulating fibrillarin and rRNAmethylation in cancer.	24029231
Partial activity is seen with many substitutions of highly conserved active site residues in human Pseudouridine synthase 1.	18648068
Partial Methylation at Am100 in 18S rRNA of Baker's Yeast Reveals Ribosome Heterogeneity on the Level of Eukaryotic rRNA Modification.	24586927
PCIF1 Catalyzes m6Am mRNA Methylation to Regulate Gene Expression.	31279659
Phylogenetic analysis of the eukaryotic RNA (cytosine-5)-methyltransferases.	19135144
Phylogenomic analysis of 16S rRNA:(guanine-N2) methyltransferases suggests new family members and reveals highly conserved motifs and a domain structure similar to other nucleic acid amino-methyltransferases.	11053259
Plasmid-mediated 16S rRNA methylases among extended-spectrum beta-lactamase-producing Enterobacteriaceae isolates.	18838598
Plasticity and diversity of tRNA anticodon determinants of substrate recognition by eukaryotic A37 isopentenyltransferases.	21873461
Pmt1, a Dnmt2 homolog in Schizosaccharomyces pombe, mediates tRNA methylation in response to nutrient signaling.	23074192
Point mutations in yeast CBF5 can abolish in vivo pseudouridylation of rRNA.	10523634
Posttranscriptional modifications in the A-loop of 23S rRNAs from selected archaea and eubacteria.	11911366
Pre-steady-state kinetic analysis of the three Escherichia coli pseudouridine synthases TruB, TruA, and RluA reveals uniformly slow catalysis.	21998096
Precursor complex structure of pseudouridine synthase TruB suggests coupling of active site perturbations to an RNA-sequestering peripheral protein domain	15987897
Presence and coding properties of 2'-O-methyl-5-carbamoylmethyluridine (ncm5Um) in the wobble position of the anticodon of tRNA(Leu) (U*AA) from brewer's yeast.	1468572
Principles Governing A-to-I RNA Editing in the Breast Cancer Transcriptome.	26440892
Probing N6-methyladenosine RNA modification status at single nucleotide resolution in mRNA and long noncoding RNA.	24141618
Probing the substrate specificity of the bacterial Pnkp/Hen1 RNA repair system using synthetic RNAs.	22190744
Profiling of RNA modifications by multiplexed stable isotope labelling.	24567952
Profound downregulation of the RNA editing enzyme ADAR2 in ALS spinal motor neurons	22226999
Properties of small rRNA methyltransferase RsmD: Mutational and kinetic study.	22535590
Protection of the Queuosine Biosynthesis Enzyme QueF from Irreversible Oxidation by a Conserved Intramolecular Disulfide	28300774
Protein degradation and dynamic tRNA thiolation fine-tune translation at elevated temperatures.	25870413
Protein phosphatase methyltransferase 1 (Ppm1p) is the sole activity responsible for modification of the major forms of protein phosphatase 2A in yeast.	11697862
Proteomic analysis of the human KEOPS complex identifies C14ORF142 as a core subunit homologous to yeast Gon7.	27903914
Proteomic and 3D structure analyses highlight the C/D box snoRNP assembly mechanism and its control	25404746
Pseudouridine at position 55 in tRNA controls the contents of other modified nucleotides for low-temperature adaptation in the extreme-thermophilic eubacterium Thermus thermophilus.	21097467
Pseudouridine formation in archaeal RNAs: The case of Haloferax volcanii.	21628430
Pseudouridine mapping in the Saccharomyces cerevisiae spliceosomal U small nuclear RNAs (snRNAs) reveals that pseudouridine synthase pus1p exhibits a dual substrate specificity for U2 snRNA and tRNA.	10022901
Pseudouridine modification in Caenorhabditis elegans spliceosomal snRNAs: unique modifications are found in regions involved in snRNA-snRNA interactions.	16236171
Pseudouridine Modification Inhibits Muscleblind-like 1 (MBNL1) Binding to CCUG Repeats and Minimally Structured RNA through Reduced RNA Flexibility.	28130447
Pseudouridine synthase 1: a site-specific synthase without strict sequence recognition requirements.	22102571
Pseudouridine synthetase Pus1 of Saccharomyces cerevisiae: kinetic characterisation, tRNA structural requirement and real-time analysis of its complex with tRNA.	10356324
Pseudouridines and pseudouridine synthases of the ribosome.	12762017
Pseudouridylation at position 32 of mitochondrial and cytoplasmic tRNAs requires two distinct enzymes in Saccharomyces cerevisiae.	15466869
Pseudouridylation goes regulatory.	21206510
Pseudouridylation of tRNA-Derived Fragments Steers Translational Control in Stem Cells.	29628141
Psi35 in the branch site recognition region of U2 small nuclear RNA is important for pre-mRNA splicing in Saccharomyces cerevisiae.	15611063
Purification and cDNA cloning of the AdoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase.	9409616
Purification and characterization of the human elongator complex.	11714725
Purification, cloning, and characterization of the 16 S RNA m2G1207 methyltransferase from Escherichia coli.	9873033
Purification, cloning, and characterization of the 16S RNA m5C967 methyltransferase from Escherichia coli.	10026269
Purification, cloning, and properties of the 16S RNA pseudouridine 516 synthase from Escherichia coli.	7612632
Purification, crystallization and preliminary crystallographic analysis of the 16S rRNA methyltransferase RsmI from Escherichia coli.	25195904
Purification, structure, and properties of Escherichia coli tRNA pseudouridine synthase I.	3276686
PUS7 mutations impair pseudouridylation in humans and cause intellectual disability and microcephaly.	30778726
Pyruvate formate lyase is structurally homologous to type I ribonucleotide reductase.	10425676
Pyruvate is the source of the two carbons that are required for formation of the imidazoline ring of 4-demethylwyosine.	22026549
Qri7/OSGEPL, the mitochondrial version of the universal Kae1/YgjD protein, is essential for mitochondrial genome maintenance.	19578062
Quantitative analysis of 5HT(2C) receptor RNA editing patterns in psychiatric disorders.	21914481
Quantitative analysis of ribonucleoside modifications in tRNA by HPLC-coupled mass spectrometry.	24625781
Radical mediated ring formation in the biosynthesis of the hypermodified tRNA base wybutosine.	23856057
Radical-mediated enzymatic methylation: a tale of two SAMS.	22097883
RAM/Fam103a1 is required for mRNA cap methylation.	22099306
Rational Design of RNA Editing Guide Strands: Cytidine Analogs at the Orphan Position.	33939417
Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma.	23291631
Recognition and Cleavage of Human tRNA Methyltransferase TRMT1 by the SARS-CoV-2 Main Protease	36865253
Recognition elements in rRNA for the tylosin resistance methyltransferase RlmA(II).	17673230
Recognition of a complex substrate by the KsgA/Dim1 family of enzymes has been conserved throughout evolution.	16540698
Recombinant human mRNA cap methyltransferase binds capping enzyme/RNA polymerase IIo complexes.	9705270
Reconstituting bacterial RNA repair and modification in vitro.	19815768
Reconstitution and characterization of eukaryotic N6-threonylcarbamoylation of tRNA using a minimal enzyme system.	23620299
Reconstitution and structural analysis of the yeast box H/ACA RNA-guided pseudouridine synthase	22085967
Reconstitution and structural analysis of the yeast box H/ACA RNA-guided pseudouridine synthase.	22085967
Reduced levels of protein recoding by A-to-I RNA editing in Alzheimer's disease	26655226
Reduced m6A modification predicts malignant phenotypes and augmented Wnt/PI3K-Akt signaling in gastric cancer.	31243897
Reduced mA mRNA methylation is correlated with the progression of human cervical cancer.	29228737
Reduced misreading of asparagine codons by Escherichia coli tRNALys with hypomodified derivatives of 5-methylaminomethyl-2-thiouridine in the wobble position.	9811540
Reduction of GluR2 RNA editing, a molecular change that increases calcium influx through AMPA receptors, selective in the spinal ventral gray of patients with amyotrophic lateral sclerosis	10589532
Region-specific alterations of A-to-I RNA editing of serotonin 2c receptor in the cortex of suicides with major depression	27576167
Regulation of expression and catalytic activity of Escherichia coli RsmG methyltransferase.	22337945
Reliable Chemical Synthesis of Oligoribonucleotides (RNA) with 2′-O-[(Triisopropylsilyl)oxy]methyl(2′-O-tom)-Protected Phosphoramidites	10.1002/1522-2675(20011219)84:12<3773::AID-HLCA377
Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins.	22760636
Requirement for IscS in biosynthesis of all thionucleosides in Escherichia coli.	12446632
Ribosomal RNA guanine-(N2)-methyltransferases and their targets.	17389639
Ribosome biogenesis factor Tsr3 is the aminocarboxypropyl transferase responsible for 18S rRNA hypermodification in yeast and humans	27084949
Rit1, a tRNA backbone-modifying enzyme that mediates initiator and elongator tRNA discrimination.	7954819
RlmCD-mediated U747 methylation promotes efficient G748 methylation by methyltransferase RlmAII in 23S rRNA in Streptococcus pneumoniae; interplay between two rRNA methylations responsible for telithr	26365244
RlmN and Cfr are radical SAM enzymes involved in methylation of ribosomal RNA	20184321
RluD, a highly conserved pseudouridine synthase, modifies 50S subunits more specifically and efficiently than free 23S rRNA.	17872507
RmtC introduces G1405 methylation in 16S rRNA and confers high-level aminoglycoside resistance on Gram-positive microorganisms.	20722735
RNA Cytidine Acetyltransferase of Small-Subunit Ribosomal RNA: Identification of Acetylation Sites and the Responsible Acetyltransferase in Fission Yeast, Schizosaccharomyces pombe.	25402480
RNA editing (R/G site) and flip–flop splicing of the AMPA receptorsubunit GluR2 in nervous tissue of epilepsy patients	15006707
RNA editing by adenosine deaminases generates RNA and protein diversity.	12457566
RNA editing in RHOQ promotes invasion potential in colorectal cancer.	24663214
RNA editing of drives early tumor invasion and metastasis in familial esophageal cancer.	28533408
RNA editing of apolipoprotein B mRNA. Sequence specificity determined by in vitrocoupled transcription editing.	2324099
RNA editing of Filamin A pre-mRNA regulates vascular contraction and diastolic blood pressure	30087110
RNA editing of the 5-HT2C receptor is reduced in schizophrenia	11443520
RNA editing of the serotonin 5HT2C receptor and its effects on cell signalling, pharmacology and brain function	18554725
RNA helicase module in an acetyltransferase that modifies a specific tRNA anticodon	19322199
RNA helicase module in an acetyltransferase that modifies a specific tRNA anticodon.	19322199
RNA helicase YTHDC2 promotes cancer metastasis via the enhancement of the efficiencyby which HIF-1α mRNA is translated.	26996300
RNA hyperediting and alternative splicing of hematopoietic cell phosphatase (PTPN6) gene in acute myeloid leukemia.	11001933
RNA m6A methyltransferase METTL3 regulates invasiveness of melanoma cells by matrixmetallopeptidase 2.	30762711
RNA mA methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail.	31061416
RNA mA Methyltransferase METTL3 Promotes The Growth Of Prostate Cancer By Regulating Hedgehog Pathway.	31806999
RNA methylation by radical SAM enzymes RlmN and Cfr proceeds via methylene transfer and hydride shift.	21368151
RNA methylation by the MIS complex regulates a cell fate decision in yeast.	22685417
RNA methylation under heat shock control.	10983982
RNA methyltransferases in plants: Breakthroughs in function and evolution	36502609
RNA methyltransferases utilize two cysteine residues in the formation of 5-methylcytosine.	12220187
RNA modification landscape of the human mitochondrial tRNA regulates protein synthesis.	30262910
RNA N6-methyladenosine demethylase FTO promotes breast tumor progression through inhibiting BNIP3.	30922314
RNA N6-methyladenosine methyltransferase-like 3 promotes liver cancer progression through YTHDF2-dependent posttranscriptional silencing of SOCS2.	29171881
RNA nucleotide methylation.	21823225
RNA recognition mechanism of eukaryote tRNA (m7G46) methyltransferase (Trm8-Trm82 complex).	17382321
RNA sequence and two-dimensional structure features required for efficient substrate modification by the Saccharomyces cerevisiae RNA:{Psi}-synthase Pus7p.	19114708
RNA-guided RNA modification: functional organization of the archaeal H/ACA RNP.	15870259
RNA-protein mutually induced fit: structure of Escherichia coli isopentenyl-tRNA transferase in complex with tRNA(Phe).	19158097
RNA-Protein Mutually Induced Fit: STRUCTURE OF ESCHERICHIA COLI ISOPENTENYL-tRNA TRANSFERASE IN COMPLEX WITH tRNA(Phe).	19158097
RNA:(guanine-N2) methyltransferases RsmC/RsmD and their homologs revisited--bioinformatic analysis and prediction of the active site based on the uncharacterized Mj0882 protein structure.	11929612
RNA:pseudouridine synthetase Pus1 from Saccharomyces cerevisiae: oligomerization property and stoichiometry of the complex with yeast tRNA(Phe).	10492022
Role of human mitochondrial Nfs1 in cytosolic iron-sulfur protein biogenesis and iron regulation.	16847322
Roles of Arabidopsis ATP/ADP isopentenyltransferases and tRNA isopentenyltransferases in cytokinin biosynthesis.	17062755
Roles of conserved amino acid sequence motifs in the SpoU (TrmH) RNA methyltransferase family.	15637073
Rrp8p is a yeast nucleolar protein functionally linked to Gar1p and involved in pre-rRNA cleavage at site A2.	10864042
rystal structure of the yeast heterodimeric ADAT2/3 deaminase.	33272269
S-Adenosyl-S-carboxymethyl-L-homocysteine: a novel cofactor found in the putative tRNA-modifying enzyme CmoA.	23695253
S-Adenosyl-S-carboxymethyl-L-homocysteine: a novel cofactor found in the putative tRNA-modifying enzyme CmoA.	23695253
S-Adenosylmethionine-dependent radical-based modification of biological macromolecules.	20951571
Saccharomyces cerevisiae Mod5p-II contains sequences antagonistic for nuclear and cytosolic locations.	9872948
SAXS analysis of the tRNA-modifying enzyme complex MnmE/MnmG reveals a novel interaction mode and GTP-induced oligomerization.	24634441
Selenium-containing tRNA(Glu) and tRNA(Lys) from Escherichia coli: purification, codon specificity and translational activity.	2679651
Selenophosphate synthetase. Enzyme properties and catalytic reaction.	8144648
Sequence analysis and overexpression of the Zymomonas mobilis tgt gene encoding tRNA-guanine transglycosylase: purification and biochemical characterization of the enzyme.	7665516
Sequence analysis and structure prediction of 23S rRNA:m1G methyltransferases reveals a conserved core augmented with a putative Zn-binding domain in the N-terminus and family-specific elaborations in the C-terminus.	11763974
Sequence analysis and structure prediction of aminoglycoside-resistance 16S rRNA:m7G methyltransferases.	11518396
Sequence analysis of a 13.4 kbp fragment from the left arm of chromosome XV reveals a malate dehydrogenase gene, a putative Ser/Thr protein kinase, the ribosomal L25 gene and four new open reading frames.	8896265
Sequence and genetic analysis of NHP2: a moderately abundant high mobility group-like nuclear protein with an essential function in Saccharomyces cerevisiae.	2063628
Sequence and properties of pIM13, a macrolide-lincosamide-streptogramin B resistance plasmid from Bacillus subtilis.	3087948
Sequence preference and structural heterogeneity of BZ junctions.	30184200
Sequence preference and structural heterogeneity of BZ junctions.	30184200
Sequence-specific and Shape-selective RNA Recognition by the Human RNA 5-Methylcytosine Methyltransferase NSun6.	27703015
Sequence-structure-function analysis of the bifunctional enzyme MnmC that catalyses the last two steps in the biosynthesis of hypermodified nucleoside mnm5s2U in tRNA.	18186482
Sequence-structure-function relationships of a tRNA (m7G46) methyltransferase studied by homology modeling and site-directed mutagenesis.	15789416
Sequence-structure-function relationships of Tgs1, the yeast snRNA/snoRNA cap hypermethylase.	12907733
Sequence-structure-function studies of tRNA:m5C methyltransferase Trm4p and its relationship to DNA:m5C and RNA:m5U methyltransferases.	15121902
Sequential 2'-O-methylation of archaeal pre-tRNATrp nucleotides is guided by the intron-encoded but trans-acting box C/D ribonucleoprotein of pre-tRNA.	15347671
Sinorhizobium meliloti YrbA binds divalent metal cations using two conserved histidines.	32970113
siRNAs compete with miRNAs for methylation by HEN1 in Arabidopsis.	20448024
Site-directed cleavage of RNA.	2438655
Site-directed mutants of 16S rRNA reveal important RNA domains for KsgA function and 30S subunit assembly.	21142019
Site-selected introduction of modified purine and pyrimidine ribonucleosides into RNA by automated phosphoramidite chemistry.	7599270
Site-specific methylation of 18S ribosomal RNA by SNORD42A is required for acutemyeloid leukemia cell proliferation.	32097467
Sites of action of two ribosomal RNA methylases responsible for resistance to aminoglycosides.	2441068
Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia.	33902106
Small-Molecule Inhibitors of METTL3, the Major Human Epitranscriptomic Writer.	32159918
Small-Molecule Inhibitors of METTL3, the Major Human Epitranscriptomic Writer.	32159918
Small-molecule modulators of TRMT2A decrease PolyQ aggregation and PolyQ-induced cell death.	35070167
Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia.	30991027
Snapshots of dynamics in synthesizing N(6)-isopentenyladenosine at the tRNA anticodon	19435325
Snapshots of dynamics in synthesizing N(6)-isopentenyladenosine at the tRNA anticodon	19435325
Snapshots of dynamics in synthesizing N(6)-isopentenyladenosine at the tRNA anticodon.	19435325
Snapshots of tRNA sulphuration via an adenylated intermediate	16871210
Snapshots of tRNA sulphuration via an adenylated intermediate	16871210
Snapshots of tRNA sulphuration via an adenylated intermediate.	16871210
Solid phase synthesis of the 5'-half of the initiator t-RNA from B. subtilis.	2508060
Solution structure of an rRNA methyltransferase (ErmAM) that confers macrolide-lincosamide-streptogramin antibiotic resistance.	9187657
Solution structure of an rRNA methyltransferase (ErmAM) that confers macrolide-lincosamide-streptogramin antibiotic resistance.	9187657
Solution structure of Kti11p from Saccharomyces cerevisiae reveals a novel zinc-binding module.	15952786
Solution structure of Kti11p from Saccharomyces cerevisiae reveals a novel zinc-binding module.	15952786
Solution structure of the RNA recognition domain of METTL3-METTL14 N6-methyladenosine methyltransferase.	29542011
Solution structure of Urm1 and its implications for the origin of protein modifiers.	16864801
Spb1p is a putative methyltransferase required for 60S ribosomal subunit biogenesis in Saccharomyces cerevisiae.	10556316
Spb1p is a yeast nucleolar protein associated with Nop1p and Nop58p that is able to bind S-adenosyl-L-methionine in vitro.	10648622
Spb1p-directed formation of Gm2922 in the ribosome catalytic center occurs at a late processing stage.	15546625
Specificity and kinetics of 23S rRNA modification enzymes RlmH and RluD.	20817755
Specificity and mechanism of RNA cap guanine-N2 methyltransferase (Tgs1).	15590684
Specificity shifts in the rRNA and tRNA nucleotide targets of archaeal and bacterial m5U methyltransferases.	21051506
SPL1-1, a Saccharomyces cerevisiae mutation affecting tRNA splicing.	8444805
Stepwise maturation of the peptidyl transferase region of human mitoribosomes.	34135320
Steroid Receptor RNA Activator (SRA) Modification by the Human Pseudouridine Synthase 1 (hPus1p): RNA Binding, Activity, and Atomic Model	24722331
Steroid Receptor RNA Activator (SRA) Modification by the Human Pseudouridine Synthase 1 (hPus1p): RNA Binding, Activity, and Atomic Model	24722331
Steroid receptor RNA activator (SRA) modification by the human pseudouridine synthase 1 (hPus1p): RNA binding, activity, and atomic model.	24722331
Stresses that Raise NpA Levels Induce Protective Nucleoside Tetraphosphate Capping of Bacterial RNA.	31178354
Structural alterations of the cysteine desulfurase IscS of Salmonella enterica serovar Typhimurium reveal substrate specificity of IscS in tRNA thiolation.	16585765
Structural analyses of NudT16-ADP-ribose complexes direct rational design of mutants with improved processing of poly(ADP-ribosyl)ated proteins.	30976021
Structural analyses of NudT16-ADP-ribose complexes direct rational design of mutants with improved processing of poly(ADP-ribosyl)ated proteins.	30976021
Structural analysis of human 2'-O-ribose methyltransferases involved in mRNA cap structure formation.	24402442
Structural analysis of human 2'-O-ribose methyltransferases involved in mRNA cap structure formation.	24402442
Structural analysis of the activation-induced deoxycytidine deaminase required in immunoglobulin diversification.	27258794
Structural analysis of the essential resuscitation promoting factor YeaZ suggests a mechanism of nucleotide regulation through dimer reorganization.	21858042
Structural analysis of the SARS-CoV-2 methyltransferase complex involved in RNA cap creation bound to sinefungin.	32709887
Structural and biochemical insights into 2'-O-methylation at the 3'-terminal nucleotide of RNA by Hen1.	19822745
Structural and biochemical insights into 2'-O-methylation at the 3'-terminal nucleotide of RNA by Hen1.	19822745
Structural and catalytic analyses of the InsP 6 kinase activities of higher plant ITPKs.	35635723
Structural and catalytic roles of the human 18SrRNA methyltransferases DIMT1 in ribosome assembly and translation	32616653
Structural and Dynamic Insights into Redundant Function of YTHDF Proteins.	33073985
Structural and evolutionary bioinformatics of the SPOUT superfamily of methyltransferases.	17338813
Structural and functional characterization of KEOPS dimerization by Pcc1 and its role in t6A biosynthesis	27302132
Structural and functional characterization of Rv2966c protein reveals an RsmD-like methyltransferase from Mycobacterium tuberculosis and the role of its N-terminal domain in target recognition	21474448
Structural and functional characterization of Rv2966c protein reveals an RsmD-like methyltransferase from Mycobacterium tuberculosis and the role of its N-terminal domain in target recognition.	21474448
Structural and functional divergence within the Dim1/KsgA family of rRNA methyltransferases.	19520088
Structural and functional divergence within the Dim1/KsgA family of rRNA methyltransferases.	19520088
Structural and functional divergence within the Dim1/KsgA family of rRNA methyltransferases.	19520088
Structural and functional evidence of high specificity of Cbf5 for ACA trinucleotide.	21149572
Structural and functional insights into human tRNA guanine transgylcosylase	34241577
Structural and functional insights into the molecular mechanism of rRNA m6A methyltransferase RlmJ.	23945937
Structural and Functional Insights Into the Molecular Mechanism of Rrna M6A Methyltransferase Rlmj.	23945937
Structural and Functional Insights Into the Molecular Mechanism of Rrna M6A Methyltransferase Rlmj.	23945937
Structural and functional insights into tRNA binding and adenosine N1-methylation by an archaeal Trm10 homologue.	26673726
Structural and Functional Insights Into tRNA Binding and Adenosine N1-Methylation by an Archaeal Trm10 Homologue.	26673726
Structural and Functional Insights Into tRNA Binding and Adenosine N1-Methylation by an Archaeal Trm10 Homologue.	26673726
Structural and functional studies of Bud23-Trm112 reveal 18S rRNA N7-G1575 methylation occurs on late 40S precursor ribosomes	25489090
Structural and functional studies of Bud23-Trm112 reveal 18S rRNA N7-G1575 methylation occurs on late 40S precursor ribosomes.	25489090
Structural and functional studies of the Thermus thermophilus 16S rRNA methyltransferase RsmG	19622680
Structural and functional studies of the Thermus thermophilus 16S rRNA methyltransferase RsmG	19622680
Structural and functional studies of the Thermus thermophilus 16S rRNA methyltransferase RsmG.	19622680
Structural and kinetic characterization of Escherichia coli TadA, the wobble-specific tRNA deaminase.	16700551
Structural and kinetic characterization of Escherichia coli TadA, the wobble-specific tRNA deaminase.	16700551
Structural and mechanistic basis of mammalian Nudt12 RNA deNADding.	31101919
Structural and thermodynamic evidence for a stabilizing role of Nop5p in S-adenosyl-L-methionine binding to fibrillarin.	15286083
Structural bases for 16 S rRNA methylation catalyzed by ArmA and RmtB methyltransferases	19303884
Structural bases for 16 S rRNA methylation catalyzed by ArmA and RmtB methyltransferases	19303884
Structural bases for 16 S rRNA methylation catalyzed by ArmA and RmtB methyltransferases.	19303884
Structural basis for binding of RNA and cofactor by a KsgA methyltransferase.	19278652
Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases.	27373337
Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases.	27373337
Structural basis for Fe-S cluster assembly and tRNA thiolation mediated by IscS protein-protein interactions.	20404999
Structural basis for Fe-S cluster assembly and tRNA thiolation mediated by IscS protein-protein interactions.	20404999
Structural basis for Fe-S cluster assembly and tRNA thiolation mediated by IscS protein-protein interactions.	20404999
Structural basis for hypermodification of the wobble uridine in tRNA by bifunctional enzyme MnmC.	23617613
Structural basis for hypermodification of the wobble uridine in tRNA by bifunctional enzyme MnmC.	23617613
Structural basis for inhibition of the fat mass and obesity associated protein (FTO)	23547775
Structural basis for late maturation steps of the human mitoribosomal large subunit.	34135318
Structural basis for lysidine formation by ATP pyrophosphatase accompanied by a lysine-specific loop and a tRNA-recognition domain.	15894617
Structural basis for lysidine formation by ATP pyrophosphatase accompanied by a lysine-specific loop and a tRNA-recognition domain.	15894617
Structural basis for m7G-cap hypermethylation of small nuclear, small nucleolar and telomerase RNA by the dimethyltransferase TGS1.	19386620
Structural basis for m7G-cap hypermethylation of small nuclear, small nucleolar and telomerase RNA by the dimethyltransferase TGS1.	19386620
Structural basis for methyl transfer by a radical SAM enzyme.	21527678
Structural basis for methyl transfer by a radical SAM enzyme.	21527678
Structural basis for METTL6-mediated m3C RNA methylation.	34922197
Structural basis for nucleotide recognition by the ectoenzyme CD203c.	29717535
Structural basis for recognition of human 7SK long noncoding RNA by the La-related protein Larp7.	29946027
Structural Basis for Regulation of METTL16, an S-Adenosylmethionine Homeostasis Factor.	30197297
Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase.	32526208
Structural basis for site-specific ribose methylation by box C/D RNA protein complexes.	21270896
Structural basis for site-specific ribose methylation by box C/D RNA protein complexes.	21270896
Structural basis for substrate binding and catalytic mechanism of a human RNA:m5C methyltransferase NSun6	28531330
Structural basis for substrate binding and catalytic mechanism of a human RNA:m5C methyltransferase NSun6.	28531330
Structural basis for substrate placement by an archaeal box C/D ribonucleoprotein particle.	20864039
Structural basis for substrate placement by an archaeal box C/D ribonucleoprotein particle.	20864039
Structural basis for substrate placement by an archaeal box C/D ribonucleoprotein particle.	20864039
Structural Basis for Sulfur Relay to RNA Mediated by Heterohexameric TusBCD Complex	16472754
Structural basis for sulfur relay to RNA mediated by heterohexameric TusBCD complex.	16472754
Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B.	27991903
Structural Basis for the Discriminative Recognition of N6-Methyladenosine RNA by the Human YT521-B Homology Domain Family of Proteins.	26318451
Structural basis for the dual U4 and U4atac snRNA-binding specificity of spliceosomal protein hPrp31.	21784869
Structural basis for the methylation of A1408 in 16S rRNA by a panaminoglycoside resistance methyltransferase NpmA from a clinical isolate and analysis of the NpmA interactions with the 30S ribosomal subunit.	21062819
Structural basis for the methylation of A1408 in 16S rRNA by a panaminoglycoside resistance methyltransferase NpmA from a clinical isolate and analysis of the NpmA interactions with the 30S ribosomal subunit.	21062819
Structural basis for the methylation of A1408 in 16S rRNA by a panaminoglycoside resistance methyltransferase NpmA from a clinical isolate and analysis of the NpmA interactions with the 30S ribosomal subunit.	21062819
Structural basis for the methylation of G1405 in 16S rRNA by aminoglycoside resistance methyltransferase Sgm from an antibiotic producer: a diversity of active sites in m7G methyltransferases.	20194115
Structural basis for the methylation of G1405 in 16S rRNA by aminoglycoside resistance methyltransferase Sgm from an antibiotic producer: a diversity of active sites in m7G methyltransferases.	20194115
Structural basis for the methylation of G1405 in 16S rRNA by aminoglycoside resistance methyltransferase Sgm from an antibiotic producer: a diversity of active sites in m7G methyltransferases.	20194115
Structural Basis for the Specificity of Human Nudt16 and its Regulation by Inosine Monophosphate.	26121039
Structural basis for translational fidelity ensured by transfer RNA lysidine synthetase.	19847269
Structural basis for translational fidelity ensured by transfer RNA lysidine synthetase.	19847269
Structural basis of 7SK RNA 5'-gamma-phosphate methylation and retention by MePCE.	30559425
Structural basis of AdoMet-dependent aminocarboxypropyl transfer reaction catalyzed by tRNA-wybutosine synthesizing enzyme, TYW2	19717466
Structural basis of AdoMet-dependent aminocarboxypropyl transfer reaction catalyzed by tRNA-wybutosine synthesizing enzyme, TYW2	19717466
Structural basis of AdoMet-dependent aminocarboxypropyl transfer reaction catalyzed by tRNA-wybutosine synthesizing enzyme, TYW2.	19717466
Structural basis of antagonism of human APOBEC3F by HIV-1 Vif.	31792451
Structural Basis of Biological Nitrile Reduction.	22787148
Structural basis of biological nitrile reduction.	22787148
Structural basis of dcp2 recognition and activation by dcp1	18280239
Structural basis of DNA binding to human YB-1 cold shock domain regulated by phosphorylation.	32710623
Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling.	34135319
Structural basis of mismatch recognition by a SARS-CoV-2 proofreading enzyme.	34315827
Structural basis of mRNA-cap recognition by Dcp1-Dcp2.	27694842
Structural basis of N6-adenosine methylation by the METTL3-METTL14 complex	27281194
Structural basis of nucleic acid recognition and 6mA demethylation by human ALKBH1.	32051559
Structural basis of prokaryotic NAD-RNA decapping by NudC	27561816
Structural basis of regulated m 7 G tRNA modification by METTL1-WDR4.	36599985
Structural basis of RNA conformational switching in the transcriptional regulator 7SK RNP.	35320752
Structural basis of RNA processing by human mitochondrial RNase P	34489609
Structural basis of tRNA agmatinylation essential for AUA codon decoding	22002223
Structural basis of tRNA agmatinylation essential for AUA codon decoding	22002223
Structural basis of tRNA agmatinylation essential for AUA codon decoding.	22002223
Structural basis of tRNA modification with CO2 fixation and methylation by wybutosine synthesizing enzyme TYW4.	19287006
Structural basis of tRNA modification with CO2 fixation and methylation by wybutosine synthesizing enzyme TYW4.	19287006
Structural bioinformatics analysis of enzymes involved in the biosynthesis pathway of the hypermodified nucleoside ms(2)io(6)A37 in tRNA.	17910062
Structural characterization of B. subtilis m1A22 tRNA methyltransferase TrmK: insights into tRNA recognition	30931478
Structural characterization of glycinamide-RNase-transformylase T fromMycobacterium tuberculosis.	31894729
Structural comparison of tRNA m(1)A58 methyltransferases revealed different molecular strategies to maintain their oligomeric architecture under extreme conditions.	22168821
Structural comparison of yeast snoRNP and spliceosomal protein Snu13p with its homologs	15963469
Structural Consequences of Nucleophosmin Mutations in Acute Myeloid Leukemia.	18511415
Structural determinants of APOBEC3B non-catalytic domain for molecular assembly and catalytic regulation.	28575276
Structural determinants of HIV-1 Vif susceptibility and DNA binding in APOBEC3F.	24185281
Structural features of the guide:target RNA duplex required for archaeal box C/D sRNA-guided nucleotide 2'-O-methylation.	17438123
Structural Insight Into hnRNP A2/B1 Homodimerization and DNA Recognition.	36528084
Structural insight into human N6amt1-Trm112 complex functioning as a protein methyltransferase.	31636962
Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis.	21087996
Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis.	21087996
Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis.	21087996
Structural insight into the mechanism of stabilization of the 7SK small nuclear RNA by LARP7.	25753663
Structural insight into the methyltransfer mechanism of the bifunctional Trm5	29214216
Structural insights into actin filament recognition by commonly used cellular actin markers	32567727
Structural insights into dimethylation of 12S rRNA by TFB1M: indispensable role in translation of mitochondrial genes and mitochondrial function.	31251801
Structural insights into dimethylation of 12S rRNA by TFB1M: indispensable role in translation of mitochondrial genes and mitochondrial function.	31251801
Structural insights into dimethylation of 12S rRNA by TFB1M: indispensable role in translation of mitochondrial genes and mitochondrial function.	31251801
Structural insights into dpCoA-RNA decapping by NudC.	34074215
Structural insights into FTO's catalytic mechanism for the demethylation of multiple RNA substrates	30718435
Structural Insights into HIV-1 Vif-APOBEC3F Interaction.	26537685
Structural insights into mechanisms of the small RNA methyltransferase HEN1.	19812675
Structural insights into mechanisms of the small RNA methyltransferase HEN1.	19812675
Structural Insights Into Methyltransferase Ksga Function in 30S Ribosomal Subunit Biogenesis	22308031
Structural insights into methyltransferase KsgA function in 30S ribosomal subunit biogenesis.	22308031
Structural insights into the catalytic mechanism of Escherichia coli selenophosphate synthetase.	22081394
Structural insights into the function of 23S rRNA methyltransferase RlmG (m2G1835) from Escherichia coli	22753782
Structural insights into the function of aminoglycoside-resistance A1408 16S rRNA methyltransferases from antibiotic-producing and human pathogenic bacteria.	20639535
Structural insights into the function of aminoglycoside-resistance A1408 16S rRNA methyltransferases from antibiotic-producing and human pathogenic bacteria.	20639535
Structural insights into the GTPase domain of Escherichia coli MnmE protein.	17143896
Structural Insights into the Methylation of C1402 in 16S rRNA by Methyltransferase RsmI	27711192
Structural insights into the molecular mechanism of the m(6)A writer complex.	27627798
Structural insights into the molecular mechanism of the m(6)A writer complex.	27627798
Structural insights into the RNA methyltransferase domain of METTL16.	29593291
Structural insights into the stimulation of S. pombe Dnmt2 catalytic efficiency by the tRNA nucleoside queuosine.	29892076
Structural Investigations on the Interactions between Cytidine Deaminase Human APOBEC3G and DNA.	31116511
Structural Investigations on the Interactions between Cytidine Deaminase Human APOBEC3G and DNA.	31116511
Structural mechanism of substrate RNA recruitment in H/ACA RNA-guided pseudouridine synthase.	19481523
Structural model of the M7G46 Methyltransferase TrmB in complex with tRNA	34006170
Structural organization of box C/D RNA-guided RNA methyltransferase.	19666563
Structural organization of box C/D RNA-guided RNA methyltransferase.	19666563
Structural rearrangements in the active site of the Thermus thermophilus 16S rRNA methyltransferase KsgA in a binary complex with 5'-methylthioadenosine.	19285505
Structural rearrangements in the active site of the Thermus thermophilus 16S rRNA methyltransferase KsgA in a binary complex with 5'-methylthioadenosine.	19285505
Structural rearrangements in the active site of the Thermus thermophilus 16S rRNA methyltransferase KsgA in a binary complex with 5'-methylthioadenosine.	19285505
Structural study of the H/ACA snoRNP components Nop10p and the 3' hairpin of U65 snoRNA	16373493
Structural study of the H/ACA snoRNP components Nop10p and the 3' hairpin of U65 snoRNA.	16373493
Structure analysis of the conserved methyltransferase domain of human trimethylguanosine synthase TGS1.	19307714
Structure analysis of the conserved methyltransferase domain of human trimethylguanosine synthase TGS1.	19307714
Structure and function of archaeal box C/D sRNP core proteins.	12598892
Structure and function of archaeal box C/D sRNP core proteins.	12598892
Structure and function of the antibiotic resistance-mediating methyltransferase AviRb from Streptomyces viridochromogenes	15581897
Structure and function of the antibiotic resistance-mediating methyltransferase AviRb from Streptomyces viridochromogenes.	15581897
Structure and function of the bacterial decapping enzyme NudC	27428510
Structure and function of the bacterial decapping enzyme NudC.	27428510
Structure and function of the NS5 methyltransferase domain from Usutu virus	36334638
Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex.	29097656
Structure and mechanism of yeast RNA triphosphatase: an essential component of the mRNA capping apparatus.	10589681
Structure and mechanism of yeast RNA triphosphatase: an essential component of the mRNA capping apparatus.	10589681
Structure and mechanism of yeast RNA triphosphatase: an essential component of the mRNA capping apparatus.	10589681
Structure and organization of Escherichia coli genes involved in biosynthesis of the deazaguanine derivative queuine, a nutrient factor for eukaryotes.	1706703
Structure and regulation of ZCCHC4 in m6A-methylation of 28S rRNA.	31695039
Structure and regulation of ZCCHC4 in mA-methylation of 28S rRNA.	31695039
Structure determination of fibrillarin from the hyperthermophilic archaeon Pyrococcus furiosus.	14975761
Structure determination of two new amino acid-containing derivatives of adenosine from tRNA of thermophilic bacteria and archaea.	1280806
Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA	19478803
Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA	19478803
Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA.	19478803
Structure of a pre-catalytic spliceosome.	28530653
Structure of a reaction intermediate mimic in t6A biosynthesis bound in the active site of the TsaBD heterodimer from Escherichia coli.	33524148
Structure of a TrmA-RNA complex: A consensus RNA fold contributes to substrate selectivity and catalysis in m5U methyltransferases.	18451029
Structure of a TrmA-RNA complex: A consensus RNA fold contributes to substrate selectivity and catalysis in m5U methyltransferases.	18451029
Structure of active human telomerase with telomere shelterin protein TPP1.	35418675
Structure of an archaeal TYW1, the enzyme catalyzing the second step of wye-base biosynthesis	17881823
Structure of an archaeal TYW1, the enzyme catalyzing the second step of wye-base biosynthesis.	17881823
Structure of an essential bacterial protein YeaZ (TM0874) from Thermotoga maritima at 2.5 A resolution.	20944216
Structure of D-tyrosyl-tRNATyr deacylase using home-source Cu Kalpha and moderate-quality iodide-SAD data: structural polymorphism and HEPES-bound enzyme states	20445234
Structure of dihydrouridine synthase C (DusC) from Escherichia coli	23908023
Structure of dihydrouridine synthase C (DusC) from Escherichia coli.	23908023
Structure of H/ACA RNP protein Nhp2p reveals cis/trans isomerization of a conserved proline at the RNA and Nop10 binding interface.	21708174
Structure of H/ACA RNP Protein Nhp2p Reveals Cis/Trans Isomerization of a Conserved Proline at the RNA and Nop10 Binding Interface.	21708174
Structure of human DNMT2, an enigmatic DNA methyltransferase homolog that displays denaturant-resistant binding to DNA.	11139614
Structure of human DNMT2, an enigmatic DNA methyltransferase homolog that displays denaturant-resistant binding to DNA.	11139614
Structure of human Fe-S assembly subcomplex reveals unexpected cysteine desulfurase architecture and acyl-ACP-ISD11 interactions.	28634302
Structure of human RNA N6-methyladenine demethylase ALKBH5 provides insights into its mechanisms of nucleic acid recognition and demethylation.	24489119
Structure of human RNA N6-methyladenine demethylase ALKBH5 provides insights into its mechanisms of nucleic acid recognition and demethylation.	24489119
Structure of human telomerase holoenzyme with bound telomeric DNA.	33883742
Structure of Nucleophosmin DNA-binding Domain and Analysis of Its Complex with a G-quadruplex Sequence from the c-MYC Promoter.	22707729
Structure of protein L7Ae bound to a K-turn derived from an archaeal box H/ACA sRNA at 1.8 A resolution.	15130481
Structure of Protein L7Ae Bound to a K-Turn Derived from an Archaeal Box H/ACA sRNA at 1.8 A Resolution.	15130481
Structure of Saccharomyces cerevisiae mitochondrial Qri7 in complex with AMP	25084372
Structure of Saccharomyces cerevisiae mitochondrial Qri7 in complex with AMP.	25084372
Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP.	11953756
Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP.	11953756
Structure of the archaeal Kae1/Bud32 fusion protein MJ1130: a model for the eukaryotic EKC/KEOPS subcomplex.	19172740
Structure of the bifunctional methyltransferase YcbY (RlmKL) that adds the m7G2069 and m2G2445 modifications in Escherichia coli 23S rRNA	22362734
Structure of the bifunctional methyltransferase YcbY (RlmKL) that adds the m7G2069 and m2G2445 modifications in Escherichia coli 23S rRNA.	22362734
Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation.	27183195
Structure of the DNA deaminase domain of the HIV-1 restriction factor APOBEC3G.	18288108
Structure of the Essential MTERF4:NSUN4 Protein Complex Reveals How an MTERF Protein Collaborates to Facilitate rRNA Modification.	23022348
Structure of the guanylyltransferase domain of human mRNA capping enzyme.	21636784
Structure of the guanylyltransferase domain of human mRNA capping enzyme.	21636784
Structure of the human frataxin-bound iron-sulfur cluster assembly complex provides insight into its activation mechanism.	31101807
Structure of the human MTERF4-NSUN4 protein complex that regulates mitochondrial ribosome biogenesis.	22949673
Structure of the human MTERF4-NSUN4 protein complex that regulates mitochondrial ribosome biogenesis.	22949673
Structure of the Kti11/Kti13 Heterodimer and Its Double Role in Modifications of tRNA and Eukaryotic Elongation Factor 2.	25543256
Structure of the Kti11/Kti13 Heterodimer and its Double Role in Modifications of tRNA and Eukaryotic Elongation Factor 2.	25543256
Structure of the Kti11/Kti13 Heterodimer and its Double Role in Modifications of tRNA and Eukaryotic Elongation Factor 2.	25543256
Structure of the Lifeact-F-actin complex	33216759
Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome.	33326748
Structure of the pseudouridine synthase RsuA from Haemophilus influenzae.	16511038
Structure of the RNA 3'-phosphate cyclase-adenylate intermediate illuminates nucleotide specificity and covalent nucleotidyl transfer.	20399182
Structure of the RNA-dependent RNA polymerase from COVID-19 virus.	32277040
Structure of the Saccharomyces cerevisiae Cet1-Ceg1 mRNA capping apparatus.	20159466
Structure of the Saccharomyces cerevisiae Cet1-Ceg1 mRNA Capping Apparatus.	20159466
Structure of the Saccharomyces cerevisiae Hrr25:Mam1 monopolin subcomplex reveals a novel kinase regulator.	27491543
Structure of the Saccharomyces cerevisiae Hrr25:Mam1 monopolin subcomplex reveals a novel kinase regulator.	27491543
Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors.	31138817
Structure of the Shq1-Cbf5-Nop10-Gar1 complex and implications for H/ACA RNP biogenesis and dyskeratosis congenita	22117216
Structure of the Shq1-Cbf5-Nop10-Gar1 complex and implications for H/ACA RNP biogenesis and dyskeratosis congenita.	22117216
Structure of the thiostrepton resistance methyltransferase.S-adenosyl-L-methionine complex and its interaction with ribosomal RNA.	19369248
Structure of the thiostrepton-resistance methyltransferase-S-adenosyl-L-methionine complex and its interaction with ribosomal RNA	19369248
Structure of the yeast tRNA m7G methylation complex.	18184583
Structure of the Yeast tRNA M7G Methylation Complex.	18184583
Structure of the YTH domain of human YTHDF2 in complex with an m(6)A mononucleotide reveals an aromatic cage for m(6)A recognition.	25412658
Structure of tRNA dimethylallyltransferase: RNA modification through a channel.	17292915
Structure of tRNA methyltransferase complex of Trm7 and Trm734 reveals a novel binding interface for tRNA recognition.	31586407
Structure of tRNA Pseudouridine Synthase TruB and Its RNA Complex: RNA Recognition Through a Combination of Rigid Docking and Induced Fit	14566049
Structure of tRNA pseudouridine synthase TruB and its RNA complex: RNA recognition through a combination of rigid docking and induced fit.	14566049
Structure of wye (Yt base) and wyosine (Yt) from Torulopsis utilis phenylalanine transfer ribonucleic acid.	942858
Structure prediction and phylogenetic analysis of a functionally diverse family of proteins homologous to the MT-A70 subunit of the human mRNA:m(6)A methyltransferase.	12355263
Structure, biosynthesis, and function of queuosine in transfer RNA.	6410456
Structure, interaction and real-time monitoring of the enzymatic reaction of wild-type APOBEC3G	19153609
Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase.	34381037
Structure-Activity Relationships and Antileukemia Effects of the Tricyclic Benzoic Acid FTO Inhibitors	35793358
Structure-Based Design of Selective Fat Mass and Obesity Associated Protein (FTO) Inhibitors	34762429
Structure-function analysis of Escherichia coli MnmG (GidA), a highly conserved tRNA-modifying enzyme.	19801413
Structure-function analysis of human TYW2 enzyme required for the biosynthesis of a highly modified Wybutosine (yW) base in phenylalanine-tRNA.	22761755
Structure-function analysis of the mRNA cap methyltransferase of Saccharomyces cerevisiae.	9169431
Structure-function analysis of yeast piD261/Bud32, an atypical protein kinase essential for normal cell life.	12023889
Structure-guided discovery of the metabolite carboxy-SAM that modulates tRNA function	23676670
Structure-guided discovery of the metabolite carboxy-SAM that modulates tRNA function.	23676670
Structures and mechanisms of tRNA methylation by METTL1-WDR4.	36599982
Structures of a putative RNA 5-methyluridine methyltransferase, Thermus thermophilus TTHA1280, and its complex with S-adenosyl-L-homocysteine.	16511182
Structures of human ADAR2 bound to dsRNA reveal base-flipping mechanism and basis for site selectivity.	27065196
Structures of human ALKBH5 demethylase reveal a unique binding mode for specific single stranded m6A RNA demethylation.	24778178
Structures of human ALKBH5 demethylase reveal a unique binding mode for specific single-stranded N6-methyladenosine RNA demethylation.	24778178
Structures of human ALKBH5 demethylase reveal a unique binding mode for specific single-stranded N6-methyladenosine RNA demethylation.	24778178
Structures of RNA 3'-phosphate cyclase bound to ATP reveal the mechanism of nucleotidyl transfer and metal-assisted catalysis.	22167800
Structures of RNA 3'-phosphate cyclase bound to ATP reveal the mechanism of nucleotidyl transfer and metal-assisted catalysis.	22167800
Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation	29794219
Structures of the human pre-catalytic spliceosome and its precursor spliceosome.	30315277
Studies on polynucleotides, lxviii the primary structure of yeast phenylalanine transfer RNA.	16591527
Studies on the function of two adjacent N6,N6-dimethyladenosines near the 3' end of 16 S ribosomal RNA of Escherichia coli. III. Purification and properties of the methylating enzyme and methylase-30 S interactions.	383712
Studies on the function of two adjacent N6,N6-dimethyladenosines near the 3' end of 16S ribosomal RNA of Escherichia coli. IV. The effect of the methylgroups on ribosomal subunit interaction.	6986611
Substitutions in an active site loop of Escherichia coli IscS result in specific defects in Fe-S cluster and thionucleoside biosynthesis in vivo.	14978044
Substrate binding analysis of the 23S rRNA methyltransferase RrmJ.	15375145
Substrate Recognition and Modification by the Nosiheptide Resistance Methyltransferase	4409310
Substrate recognition of tRNA (Guanosine-2'-)-methyltransferase from Thermus thermophilus HB27.	9748240
Substrate requirements for ErmC' methyltransferase activity.	7543473
Substrate RNA positioning in the archaeal H/ACA ribonucleoprotein complex	18059286
Substrate specificity and properties of the Escherichia coli 16S rRNA methyltransferase, RsmE.	17872509
Substrate specificity of the pseudouridine synthase RluD in Escherichia coli.	17937767
Substrate tRNA recognition mechanism of a multisite-specific tRNA methyltransferase, Aquifex aeolicus Trm1, based on the X-ray crystal structure	21844194
Substrate tRNA recognition mechanism of a multisite-specific tRNA methyltransferase, Aquifex aeolicus Trm1, based on the X-ray crystal structure	21844194
Substrate tRNA recognition mechanism of a multisite-specific tRNA methyltransferase, Aquifex aeolicus Trm1, based on the X-ray crystal structure.	21844194
Substrate tRNA recognition mechanism of eubacterial tRNA (m1A58) methyltransferase (TrmI).	25593312
SufA/IscA: reactivity studies of a class of scaffold proteins involved in [Fe-S] cluster assembly.	15278785
Suppression of mA reader Ythdf2 promotes hematopoietic stem cell expansion.	30065315
Switching Demethylation Activities between AlkB Family RNA/DNA Demethylases through Exchange of Active-Site Residues.	24596302
Synthesis and Characterization of the Native Anticodon Domain of E. coli tRNALys: Simultaneous Incorporation of Modified Nucleosides mnm5s2U, t6A, and Pseudouridine Using Phosphoramidite Chemistry	10970299
Synthesis and hybridization studies on two complementary nona(2'-O-methyl)ribonucleotides.	3627981
Synthesis and Incorporation of 2′-O-Methyl-Pseudouridine into Oligonucleotides	10.1080/07328319708006226
Synthesis and properties of 2'-O-methyl-2-thiouridine and oligoribonucleotides containing 2'-O-methyl-2-thiouridine.	10969970
Synthesis and studies on the effect of 2-thiouridine and 4-thiouridine on sugar conformation and RNA duplex stability.	9092639
Synthesis of 2′-O-[(Triisopropylsilyl)oxy]methyl (= tom)-Protected Ribonucleoside Phosphoramidites Containing Various Nucleobase Analogues	10.1002/hlca.200590209
Synthesis of a 3-methyluridine phosphoramidite to investigate the role of methylation in a ribosomal RNA hairpin.	11741781
Synthesis of helix 69 of Escherichia coli 23S rRNA containing its natural modified nucleosides, m(3)Psi and Psi.	12467398
Synthesis of modified nucleosides for the incorporation into tRNAs
Synthesis of N-Methylated Ribonucleosides for RNA Synthesis	10.1002/hlca.200390205
Synthesis of the Anticodon Hairpin tRNAfMet Containing N-{[9-(β-D-Ribofuranosyl)-9H-purin-6-yl]carbamoyl}-L-threonine (=N6-{{[(1S,2R)-1-Carboxy-2-hydroxypropyl]amino}carbonyl}adenosine, t6A)	10.1002/(SICI)1522-2675(20000119)83:1<152::AID-HLC
Synthesis of the tRNALys,3 Anticodon Stem-Loop Domain Containing the Hypermodified ms2t6A Nucleoside	12126427
Synthesis, base pairing properties and trans-lesion synthesis by reverse transcriptases of oligoribonucleotides containing the oxidatively damaged base 5-hydroxycytidine.	21852326
Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.	17643375
Tad1p, a yeast tRNA-specific adenosine deaminase, is related to the mammalian pre-mRNA editing enzymes ADAR1 and ADAR2.	9707437
tadA, an essential tRNA-specific adenosine deaminase from Escherichia coli.	12110595
Target recognition, RNA methylation activity and transcriptional regulation of the Dictyostelium discoideum Dnmt2-homologue (DnmA)	23877245
Targeting the RNA m(6)A Reader YTHDF2 Selectively Compromises Cancer Stem Cells inAcute Myeloid Leukemia.	31031138
Taurine as a constituent of mitochondrial tRNAs: new insights into the functions of taurine and human mitochondrial diseases.	12456664
Taurine-containing uridine modifications in tRNA anticodons are required to decipher non-universal genetic codes in ascidian mitochondria	21873425
Temperature sensitive nop2 alleles defective in synthesis of 25S rRNA and large ribosomal subunits in Saccharomyces cerevisiae.	11452018
Tertiary network in mammalian mitochondrial tRNAAsp revealed by solution probing and phylogeny.	19767615
Tertiary structure checkpoint at anticodon loop modification in tRNA functional maturation	19749755
Tertiary structure checkpoint at anticodon loop modification in tRNA functional maturation.	19749755
Tertiary structure checkpoint at anticodon loop modification in tRNA functional maturation.	19749755
The 18S ribosomal RNA m6 A methyltransferase Mettl5 is required for normal walking behavior in Drosophila.	32350990
The 18S rRNA dimethylase Dim1p is required for pre-ribosomal RNA processing in yeast.	7590228
The 2'-O-methyltransferase responsible for modification of yeast tRNA at position 4.	17242307
The 2-thiouridylase function of the human MTU1 (TRMU) enzyme is dispensable for mitochondrial translation.	21890497
The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism.	10366505
The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism.	10366505
The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism.	10366505
The 3.8 angstrom structure of the U4/U6.U5 tri-snRNP: Insights into spliceosome assembly and catalysis	26743623
The activity of an ancient atypical protein kinase is stimulated by ADP-ribose in vitro.	21527241
The ADAR protein family	23273215
The Alazami Syndrome-Associated Protein LARP7 Guides U6 Small Nuclear RNA Modification and Contributes to Splicing Robustness.	32017898
The AlkB domain of mammalian ABH8 catalyzes hydroxylation of 5-methoxycarbonylmethyluridine at the wobble position of tRNA.	20583019
The aminoglycoside resistance methyltransferase Sgm impedes RsmF methylation at an adjacent rRNA nucleotide in the ribosomal A site.	19509304
The Antiviral and Cancer Genomic DNA Deaminase APOBEC3H Is Regulated by an RNA-Mediated Dimerization Mechanism.	29290613
The ApaH-like phosphatase TbALPH1 is the major mRNA decapping enzyme of trypanosomes	28628654
The APOBEC-2 crystal structure and functional implications for the deaminase AID.	17187054
The APOBEC3C crystal structure and the interface for HIV-1 Vif binding.	23001005
The archaeal COG1901/DUF358 SPOUT-methyltransferase members, together with pseudouridine synthase Pus10, catalyze the formation of 1-methylpseudouridine at position 54 of tRNA.	22274953
The archaeon Haloarcula marismortui has few modifications in the central parts of its 23S ribosomal RNA.	15826654
The Association Between the FTO rs9939609 Variant and Malignant Pleural Mesothelioma Risk: A Case-Control Study.	29260910
The ATP-mediated formation of the YgjD-YeaZ-YjeE complex is required for the biosynthesis of tRNA t6A in Escherichia coli	25578970
The ATPase activity of an 'essential' Bacillus subtilis enzyme, YdiB, is required for its cellular function and is modulated by oligomerization.	19246765
The avilamycin resistance determinants AviRa and AviRb methylate 23S rRNA at the guanosine 2535 base and the uridine 2479 ribose.	12828631
The Bacillus subtilis open reading frame ysgA encodes the SPOUT methyltransferase RlmP forming 2'- O-methylguanosine at position 2553 in the A-loop of 23S rRNA	35710145
The bipartite structure of the tRNA m1A58 methyltransferase from S. cerevisiae is conserved in humans.	16043508
The Bowen-Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Psi1191 in yeast 18S rRNA.	20972225
The box H + ACA snoRNAs carry Cbf5p, the putative rRNA pseudouridine synthase.	9472021
The box H/ACA ribonucleoprotein complex: interplay of RNA and protein structures in post-transcriptional RNA modification.	19917616
The box H/ACA RNP assembly factor Naf1p contains a domain homologous to Gar1p mediating its interaction with Cbf5p.	17612558
The C-terminal end of the Trypanosoma brucei editing deaminase plays a critical role in tRNA binding.	21602302
The carboxyl-terminal extension of yeast tRNA m5C methyltransferase enhances the catalytic efficiency of the amino-terminal domain.	17567576
The catalytic domain of topological knot tRNA methyltransferase (TrmH) discriminates between substrate tRNA and non-substrate tRNA via an induced-fit process.	23867454
The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs.	16286935
The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs.	16286935
The Cm56 tRNA modification in archaea is catalyzed either by a specific 2'-O-methylase, or a C/D sRNP.	15987815
The coiled-coil domain of the Nop56/58 core protein is dispensable for sRNP assembly but is critical for archaeal box C/D sRNP-guided nucleotide methylation.	16601205
The complete set of H/ACA snoRNAs that guide rRNA pseudouridylations in Saccharomyces cerevisiae.	15923376
The complete set of tRNA species in Nanoarchaeum equitans.	15893316
The complete structure of small.subunit processome	28945246
The complete structure of the small-subunit processome.	28945246
The conformation of 23S rRNA nucleotide A2058 determines its recognition by the ErmE methyltransferase.	7489511
The conserved Cys-X1-X2-Cys motif present in the TtcA protein is required for the thiolation of cytidine in position 32 of tRNA from Salmonella enterica serovar Typhimurium.	14729701
The conserved Wobble uridine tRNA thiolase Ctu1-Ctu2 is required to maintain genome integrity.	18391219
The critical function of the plastid rRNA methyltransferase, CMAL, in ribosome biogenesis and plant development.	32095829
The crystal structure and small-angle X-ray analysis of CsdL/TcdA reveal a new tRNA binding motif in the MoeB/E1 superfamily.	25897750
The Crystal Structure and Small-Angle X-Ray Analysis of Csdl/Tcda Reveal a New tRNA Binding Motif in the Moeb/E1 Superfamily.	25897750
The crystal structure of E. coli rRNA pseudouridine synthase RluE.	17320904
The Crystal Structure of E. coli rRNA Pseudouridine Synthase RluE.	17320904
The crystal structure of Nep1 reveals an extended SPOUT-class methyltransferase fold and a pre-organized SAM-binding site.	18208838
The crystal structure of Nep1 reveals an extended SPOUT-class methyltransferase fold and a pre-organized SAM-binding site.	18208838
The crystal structure of Pyrococcus abyssi tRNA (uracil-54, C5)-methyltransferase provides insights into its tRNA specificity.	18653523
The Crystal Structure of Pyrococcus Abyssi tRNA (Uracil-54, C5)-Methyltransferase Provides Insights Into its tRNA Specificity.	18653523
The Crystal Structure of Pyrococcus Abyssi tRNA (Uracil-54, C5)-Methyltransferase Provides Insights Into its tRNA Specificity.	18653523
The crystal structure of the lysyl-tRNA synthetase (LysU) from Escherichia coli	7735833
The crystal structure of the lysyl-tRNA synthetase (LysU) from Escherichia coli.	7735833
The crystal structure of the Methanocaldococcus jannaschii multifunctional L7Ae RNA-binding protein reveals an induced-fit interaction with the box C/D RNAs.	16008351
The crystal structure of the Methanocaldococcus jannaschii multifunctional L7Ae RNA-binding protein reveals an induced-fit interaction with the box C/D RNAs.	16008351
The Crystal Structure of the Methanocaldococcus jannaschii Multifunctional L7Ae RNA-Binding Protein Reveals an Induced-Fit Interaction with the Box C/D RNAs.	16008351
The crystal structure of the Pyrococcus abyssi mono-functional methyltransferase PaTrm5b	28911863
The Crystal Structure of the Z[beta] Domain of the RNA-editing Enzyme ADAR1 Reveals Distinct Conserved Surfaces Among Z-domains.	16023667
The cysteine desulfurase IscS is required for synthesis of all five thiolated nucleosides present in tRNA from Salmonella enterica serovar typhimurium.	12446633
The deazapurine biosynthetic pathway revealed: in vitro enzymatic synthesis of PreQ(0) from guanosine 5'-triphosphate in four steps.	19354300
The DIM1 gene responsible for the conserved m6(2)Am6(2)A dimethylation in the 3'-terminal loop of 18 S rRNA is essential in yeast.	8064863
The Dnmt2 RNA methyltransferase homolog of Geobacter sulfurreducens specifically methylates tRNA-Glu.	24711368
The effect of FTO rs9939609 on major depression differs across MDD subtypes.	24492350
The effect of FTO rs9939609 on major depression differs across MDD subtypes.	24492350
The Elongator Subcomplex Elp456 is a Hexameric Reca-Like ATPase.	22343726
The elp2 subunit is essential for elongator complex assembly and functional regulation	25960406
The epitranscriptome m6A writer METTL3 promotes chemo- and radioresistance in pancreatic cancer cells.	29345285
The Era GTPase recognizes the GAUCACCUCC sequence and binds helix 45 near the 3' end of 16S rRNA.	The Era GTPase recognizes the GAUCACCUCC sequence and binds helix 45 near the 3' end of 16S rRNA.
The Escherichia coli FtsH protein is a prokaryotic member of a protein family of putative ATPases involved in membrane functions, cell cycle control, and gene expression.	8444796
The Escherichia coli RlmN methyltransferase is a dual-specificity enzyme that modifies both rRNA and tRNA and controls translational accuracy.	22891362
The Escherichia coli trmE (mnmE) gene, involved in tRNA modification, codes for an evolutionarily conserved GTPase with unusual biochemical properties.	10601028
The Escherichia coli YadB gene product reveals a novel aminoacyl-tRNA synthetase like activity.	15003446
The Escherichia coli YadB gene product reveals a novel aminoacyl-tRNA synthetase like activity.	15003446
The essential Gcd10p-Gcd14p nuclear complex is required for 1-methyladenosine modification and maturation of initiator methionyl-tRNA.	9851972
The essential interaction between yeast mRNA capping enzyme subunits is not required for triphosphatase function in vivo.	11094081
The expansion of Inosine at the wobble position of tRNAs, and its role in the evolution of proteomes	30590541
The First Structure of an RNA m5C Methyltransferase, Fmu, Provides Insight into Catalytic Mechanism and Specific Binding of RNA Substrate	14656444
The first structure of an RNA m5C methyltransferase, Fmu, provides insight into catalytic mechanism and specific binding of RNA substrate.	14656444
The flavoprotein Mcap0476 (RlmFO) catalyzes m5U1939 modification in Mycoplasma capricolum 23S rRNA.	24939895
The FtsJ/RrmJ heat shock protein of Escherichia coli is a 23 S ribosomal RNA methyltransferase.	10748051
The Gcd10p/Gcd14p complex is the essential two-subunit tRNA(1-methyladenosine) methyltransferase of Saccharomyces cerevisiae.	10779558
The GTPase activity and C-terminal cysteine of the Escherichia coli MnmE protein are essential for its tRNA modifying function.	12730230
The H/ACA RNP assembly factor SHQ1 functions as an RNA mimic.	22085966
The Handling of the Mechanistic Probe 5-Fluorouridine by the Pseudouridine Synthase TruA and Its Consistency with the Handling of the Same Probe by the Pseudouridine Synthases TruB and RluA.	21142053
The highly conserved KEOPS/EKC complex is essential for a universal tRNA modification, t6A.	21183954
The human 18S rRNA base methyltransferases DIMT1L and WBSCR22-TRMT112 but not rRNA modification are required for ribosome biogenesis.	25851604
The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112.	31328227
The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112.	31328227
The human EKC/KEOPS complex is recruited to Cullin2 ubiquitin ligases by the human tumour antigen PRAME.	22912744
The human interferon-regulated ISG95 protein interacts with RNA polymerase II and shows methyltransferase activity.	18533109
The human methyltransferase ZCCHC4 catalyses N6-methyladenosine modification of 28S ribosomal RNA.	31799605
The human mitochondrial 12S rRNA mC methyltransferase METTL15 is required for mitochondrial function.	32371392
The human ortholog of archaeal Pus10 produces pseudouridine 54 in select tRNAs where its recognition sequence contains a modified residue.	30530625
The Human tRNA m ( 5) C methyltransferase Misu is multisite-specific.	22995836
The human tRNA(m(2)(2)G(26))dimethyltransferase: functional expression and characterization of a cloned hTRM1 gene.	10982862
The identification of the tRNA substrates for the supK tRNA methylase.	347399
The immunophilin-interacting protein AtFIP37 from Arabidopsis is essential for plant development and is involved in trichome endoreduplication	15047892
The isolation and characterization of N-[9-(beta-D-ribofuranosyl)-purin-6-ylcarbamoyl]glycine from yeast transfer RNA.	5503779
The K-loop, a general feature of the Pyrococcus C/D guide RNAs, is an RNA structural motif related to the K-turn.	16293637
The last rRNA methyltransferase of E. coli revealed: the yhiR gene encodes adenine-N6 methyltransferase specific for modification of A2030 of 23S ribosomal RNA.	22847818
The m(6)A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells.	27117702
The m1A58 modification in eubacterial tRNA: An overview of tRNA recognition and mechanism of catalysis by Trm	26189113
The m6A demethylase FTO promotes the growth of lung cancer cells by regulating them6A level of USP7 mRNA.	30905413
The m6A methyltransferase METTL3 promotes osteosarcoma progression by regulating them6A level of LEF1.	31253399
The M6A methyltransferase METTL3: acting as a tumor suppressor in renal cell carcinoma.	29221190
The mA eraser FTO facilitates proliferation and migration of human cervical cancer cells.	31827395
The mA methyltransferase METTL3 promotes bladder cancer progression via AFF4/NF-κB/MYC signaling network.	30659266
The mA-suppressed P2RX6 activation promotes renal cancer cells migration and invasion through ATP-induced Ca influx modulating ERK1/2 phosphorylation and MMP9 signaling pathway.	31159832
The methyl group of the N6-methyl-N6-threonylcarbamoyladenosine in tRNA of Escherichia coli modestly improves the efficiency of the tRNA.	9537379
The methylthiolation reaction mediated by the Radical-SAM enzymes.	22178611
The methyltransferase adaptor protein Trm112 is involved in biogenesis of both ribosomal subunits.	22956767
The methyltransferase YfgB/RlmN is responsible for modification of adenosine 2503 in 23S rRNA.	18025251
The METTL5-TRMT112 N6-methyladenosine methyltransferase complex regulates mRNA translation via 18S rRNA methylation	35033535
The modified wobble nucleoside uridine-5-oxyacetic acid in tRNAPro(cmo5UGG) promotes reading of all four proline codons in vivo.	15383682
The ms2io6A37 modification of tRNA in Salmonella typhimurium regulates growth on citric acid cycle intermediates.	9620964
The N-methyladenosine (mA)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells.	28920958
The NADH diphosphatase encoded by the Saccharomyces cerevisiae NPY1 nudix hydrolase gene is located in peroxisomes.	11361135
The Neurofibromatosis Type I Messenger RNA Undergoes Base-Modification RNA Editing	8602361
The nucleotide sequence of a threonine transfer ribonucleic acid from Escherichia coli.	4608712
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.	9169867
The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.	9169869
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications.	9169873
The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.	9169875
The O-Carbamoyltransferase TobZ Catalyzes an Ancient Enzymatic Reaction.	22383337
The obesity related gene, FTO, interacts with APOE, and is associated withAlzheimer's disease risk: a prospective cohort study.	21098976
The open reading frame TTC1157 of Thermus thermophilus HB27 encodes the methyltransferase forming N(2)-methylguanosine at position 6 in tRNA.	22337946
The output of the tRNA modification pathways controlled by the Escherichia coli MnmEG and MnmC enzymes depends on the growth conditions and the tRNA species.	24293650
The p27 catalytic subunit of the apolipoprotein B mRNA editing enzyme is a cytidine deaminase	8407891
The presence of modified nucleotides is required for cloverleaf folding of a human mitochondrial tRNA.	9512533
The presence of N-[9-(beta-D-ribofuranosyl)purin-6-ylcarbamoyl]threonine in serine, methionine and lysine transfer RNA's from Escherichia coli.	4902784
The protective effect of the obesity-associated rs9939609 A variant in fat mass- and obesity-associated gene on depression.	23164817
The protective effect of the obesity-associated rs9939609 A variant in fat mass- and obesity-associated gene on depression.	23164817
The pseudouridine synthase RluD is required for normal ribosome assembly and function in Escherichia coli.	15928344
The Pseudouridine Synthase RPUSD4 Is an Essential Component of Mitochondrial RNA Granules.	28082677
The ribosomal components responsible for kasugamycin dependence, and its suppression, in a mutant of Escherichia coli.	6988670
The ribosomal RNA m5C methyltransferase NSUN-1 modulates healthspan and oogenesis in Caenorhabditis elegans	33289480
The ribosome assembly factor Nep1 responsible for Bowen-Conradi syndrome is a pseudouridine-N1-specific methyltransferase	20047967
The ribosome assembly factor Nep1 responsible for Bowen-Conradi syndrome is a pseudouridine-N1-specific methyltransferase.	20047967
The rlmB gene is essential for formation of Gm2251 in 23S rRNA but not for ribosome maturation in Escherichia coli.	11698387
The rluC gene of Escherichia coli codes for a pseudouridine synthase that is solely responsible for synthesis of pseudouridine at positions 955, 2504, and 2580 in 23 S ribosomal RNA.	9660827
The RNA acetyltransferase driven by ATP hydrolysis synthesizes N4-acetylcytidine of tRNA anticodon.	18668122
The RNA editing enzyme APOBEC1 induces somatic mutations and a compatible mutational signature is present in esophageal adenocarcinomas	25085003
The RNA methyltransferase NSUN6 suppresses pancreatic cancer development by regulating cell proliferation.	33418496
The RNA Modification Database: 1999 update.	9847178
The role of the cysteine residues of ThiI in the generation of 4-thiouridine in tRNA.	11443125
The rRNA mA methyltransferase METTL5 is involved in pluripotency and developmental programs.	32217665
The Saccharomyces cerevisiae Pus2 protein encoded by YGL063w ORF is a mitochondrial tRNA:Psi27/28-synthase.	17684231
The Saccharomyces cerevisiae TAN1 gene is required for N4-acetylcytidine formation in tRNA.	15037780
The Saccharomyces cerevisiae U2 snRNA:pseudouridine-synthase Pus7p is a novel multisite-multisubstrate RNA:Psi-synthase also acting on tRNAs.	14561887
The scavenger mRNA decapping enzyme DcpS is a member of the HIT family of pyrophosphatases.	12198172
The small nucleolar RNP protein NOP1 (fibrillarin) is required for pre-rRNA processing in yeast.	1825809
The Solution Structure and DNA-Binding Properties of the Cold-Shock Domain of the Human Y-Box Protein Yb-1.	11851341
The solution structure of the Zalpha domain of the human RNA editing enzyme ADAR1 reveals a prepositioned binding surface for Z-DNA.	10535945
The specificities of four yeast dihydrouridine synthases for cytoplasmic tRNAs.	14970222
The spoU gene of Escherichia coli, the fourth gene of the spoT operon, is essential for tRNA (Gm18) 2'-O-methyltransferase activity.	9321663
The ssDNA Mutator APOBEC3A Is Regulated by Cooperative Dimerization.	25914058
The structural basis for specific decoding of AUA by isoleucine tRNA on the ribosome.	23542153
The structural basis for tRNA recognition and pseudouridine formation by pseudouridine synthase I.	10625422
The Structural Basis of Edc3- and Scd6-Mediated Activation of the Dcp1:Dcp2 Mrna Decapping Complex	22085934
The structural gene (trmD) for the tRNA(m1G)methyltransferase is part of a four polypeptide operon in Escherichia coli K-12.	6298574
The structure of APOBEC1 and insights into its RNA and DNA substrate selectivity.	33094286
The Structure of Escherichia coli TcdA (Also Known As CsdL) Reveals a Novel Topology and Provides Insight into the tRNA Binding Surface Required for N(6)-Threonylcarbamoyladenosine Dehydratase Activity.	26101842
The Structure of Escherichia coli TcdA (Also Known As CsdL) Reveals a Novel Topology and Provides Insight into the tRNA Binding Surface Required for N-Threonylcarbamoyladenosine Dehydratase Activity.	26101842
The Structure of the Box C/D Enzyme Reveals Regulation of RNA Methylation.	24121435
The structure of the hypothetical protein smu.1377c from Streptococcus mutans suggests a role in tRNA modification.	20606270
The Structure of the Rlmb 23S Rrna Methyltransferase Reveals a New Methyltransferase Fold with a Unique Knot	12377117
The structure of the RlmB 23S rRNA methyltransferase reveals a new methyltransferase fold with a unique knot.	12377117
The structure of the RNA m5C methyltransferase YebU from Escherichia coli reveals a C-terminal RNA-recruiting PUA domain	16793063
The structure of the RNA m5C methyltransferase YebU from Escherichia coli reveals a C-terminal RNA-recruiting PUA domain.	16793063
The structure of the TrmE GTP-binding protein and its implications for tRNA modification	15616586
The structure of the TrmE GTP-binding protein and its implications for tRNA modification.	15616586
The structure of the TsaB/TsaD/TsaE complex reveals an unexpected mechanism for the bacterial t6A tRNA-modification.	29741707
The structure of the yrdC gene product from Escherichia coli reveals a new fold and suggests a role in RNA binding.	11206077
The structure of the yrdC gene product from Escherichia coli reveals a new fold and suggests a role in RNA binding.	11206077
The structures of non-CG-repeat Z-DNAs co-crystallized with the Z-DNA-binding domain, hZ{alpha}ADAR1	19074195
The structures of non-CG-repeat Z-DNAs co-crystallized with the Z-DNA-binding domain, hZ{alpha}ADAR1	19074195
The study of METTL3 and METTL14 expressions in childhood ETV6/RUNX1-positive acute lymphoblastic leukemia.	31429529
The Sua5 protein is essential for normal translational regulation in yeast.	19884342
The sulfurtransferase activity of Uba4 presents a link between ubiquitin-like protein conjugation and activation of sulfur carrier proteins	18491921
The synthesis of 2'-O-[(Triisopropylsilyl)oxy] methyl (TOM) phosphoramidites of methylated ribonucleosides (m1G, m2G, m22G, m1I, m3U, m4C, m6A, m62A) for use in automated RNA solid-phase synthesis
The Synthesis of Allyl- and Ailyioxycarbonyl-Protected RNA Phosphoramidites. Useful Reagents for Solid-Phase Synthesis of RNAs with Base-Labile Modifications	10.1016/S0040-4039(98)00157-9
The synthesis of oligoribonucleotides containing N6-alkyladenosines and 2-methylthio-N6-alkyladenosines via post-synthetic modification of precursor oligomers.	12888506
The Treacher Collins syndrome (TCOF1) gene product is involved in pre-rRNAmethylation.	15930015
The tRNA methyltransferase NSun2 stabilizes p16INK⁴ mRNA by methylating the 3'-untranslated region of p16.	22395603
The tRNA recognition mechanism of folate/FAD-dependent tRNA methyltransferase (TrmFO).	23095745
The tRNA recognition mechanism of the minimalist SPOUT methyltransferase, TrmL	23804755
The tRNA recognition mechanism of the minimalist SPOUT methyltransferase, TrmL	23804755
The tRNA recognition mechanism of the minimalist SPOUT methyltransferase, TrmL.	23804755
The tylosin-resistance methyltransferase RlmA(II) (TlrB) modifies the N-1 position of 23S rRNA nucleotide G748.	15046978
The U6 snRNA m6A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention	28525753
The universal Kae1 protein and the associated Bud32 kinase (PRPK), a mysterious protein couple probably essential for genome maintenance in Archaea and Eukarya.	19143597
The universal YrdC/Sua5 family is required for the formation of threonylcarbamoyladenosine in tRNA.	19287007
The use of labilebaseprotectinggroups in oligoribonucleotidesynthesis	10.1016/S0040-4039(01)80326-9
The wobble hypothesis revisited: uridine-5-oxyacetic acid is critical for reading of G-ending codons.	17942742
The ybiN gene of Escherichia coli encodes adenine-N6 methyltransferase specific for modification of A1618 of 23 S ribosomal RNA, a methylated residue located close to the ribosomal exit tunnel.	18021804
The yeast gene YNL292w encodes a pseudouridine synthase (Pus4) catalyzing the formation of psi55 in both mitochondrial and cytoplasmic tRNAs.	9358157
The yeast ribosome synthesis factor Emg1 is a novel member of the superfamily of alpha/beta knot fold methyltransferases.	18063569
The Yeast Ribosome Synthesis Factor Emg1 is a Novel Member of the Superfamily of Alpha/Beta Knot Fold Methyltransferases.	18063569
The yeast Saccharomyces cerevisiae YDL112w ORF encodes the putative 2'-O-ribose methyltransferase catalyzing the formation of Gm18 in tRNAs.	9917067
The yeast tRNA:pseudouridine synthase Pus1p displays a multisite substrate specificity.	9671058
The yfhQ gene of Escherichia coli encodes a tRNA:Cm32/Um32 methyltransferase.	16848900
The yfiC gene of E. coli encodes an adenine-N6 methyltransferase that specifically modifies A37 of tRNA1Val(cmo5UAC).	19383770
The yggH gene of Escherichia coli encodes a tRNA (m7G46) methyltransferase.	12730187
The YqfN protein of Bacillus subtilis is the tRNA: m1A22 methyltransferase (TrmK).	18420655
Thio-modification of yeast cytosolic tRNA requires a ubiquitin-related system that resembles bacterial sulfur transfer systems.	18664566
Thiobases in Escherchia coli Transfer RNA: 2-Thiocytosine and 5-Methylaminomethyl-2-thiouracil.	17812290
Three distinct 3-methylcytidine (m(3)C) methyltransferases modify tRNA and mRNA in mice and humans.	28655767
THUMP from archaeal tRNA:m22G10 methyltransferase, a genuine autonomously folding domain.	16687654
THUMP--a predicted RNA-binding domain shared by 4-thiouridine, pseudouridine synthases and RNA methylases.	11295541
THUMPD3-TRMT112 is a m2G methyltransferase working on a broad range of tRNA substrates.	34669960
Topological Characterization of Human and Mouse mC Epitranscriptome Revealed by Bisulfite Sequencing.	30009162
TRAM, a predicted RNA-binding domain, common to tRNA uracil methylation and adenine thiolation enzymes.	11313137
Transcriptome-wide map of mA circRNAs identified in a rat model of hypoxia mediated pulmonary hypertension.	31931709
Transfer and isomerization of the ribose moiety of AdoMet during the biosynthesis of queuosine tRNAs, a new unique reaction catalyzed by the QueA protein from Escherichia coli.	7849103
Transfer RNA demethylase ALKBH3 promotes cancer progression via induction oftRNA-derived small RNAs.	30541109
Transfer RNA modification enzymes from Pyrococcus furiosus: detection of the enzymatic activities in vitro.	9973619
Transfer RNA recognition by the Escherichia coli delta2-isopentenyl-pyrophosphate:tRNA delta2-isopentenyl transferase: dependence on the anticodon arm structure.	9214656
Transfer RNA(5-methylaminomethyl-2-thiouridine)-methyltransferase from Escherichia coli K-12 has two enzymatic activities.	3298234
Transfer RNA-pseudouridine synthetase Pus1 of Saccharomyces cerevisiae contains one atom of zinc essential for its native conformation and tRNA recognition.	9585540
Translational adaptation to heat stress is mediated by RNA 5-methylcytosine in Caenorhabditis elegans	33283887
Translational defects of Escherichia coli mutants deficient in the Um(2552) 23S ribosomal RNA methyltransferase RrmJ/FTSJ.	10814528
Translational infidelity-induced protein stress results from a deficiency in Trm9-catalyzed tRNA modifications.	22832247
Translational misreading: a tRNA modification counteracts a +2 ribosomal frameshift.	11544186
Trm112 Is Required for Bud23-Mediated Methylation of the 18S rRNA at Position G1575.	22493060
Trm112p is a 15-kDa zinc finger protein essential for the activity of two tRNA and one protein methyltransferases in yeast.	20400505
Trm11p and Trm112p are both required for the formation of 2-methylguanosine at position 10 in yeast tRNA.	15899842
Trm13p, the tRNA:Xm4 modification enzyme from Saccharomyces cerevisiae is a member of the Rossmann-fold MTase superfamily: prediction of structure and active site.	19697067
Trm4 and Nsun2 RNA:mC Methyltransferases Form Metabolite-Dependent, Covalent Adducts with Previously Methylated RNA.	25375641
TRM6/61 connects PKCα with translational control through tRNAi(Met) stabilization: impact on tumorigenesis.	26234676
Trm7p catalyses the formation of two 2'-O-methylriboses in yeast tRNA anticodon loop.	11927565
Trm9-Catalyzed tRNA Modifications Regulate Global Protein Expression by Codon-Biased Translation	26670883
TRMT1-Catalyzed tRNA Modifications Are Required for Redox Homeostasis To Ensure Proper Cellular Proliferation and Oxidative Stress Survival	28784718
TRMT10A dysfunction is associated with abnormalities in glucose homeostasis, short stature and microcephaly.	25053765
TRMT2B is responsible for both tRNA and rRNA mU-methylation in human mitochondria.	31948311
Trmt61B is a methyltransferase responsible for 1-methyladenosine at position 58 of human mitochondrial tRNAs.	23097428
tRNA binding, positioning and modification by the pseudouridine synthase Pus10.	23743107
tRNA m7G methyltransferase Trm8p/Trm82p: evidence linking activity to a growth phenotype and implicating Trm82p in maintaining levels of active Trm8p.	15811913
tRNA N6-adenosine threonylcarbamoyltransferase defect due to KAE1/TCS3 (OSGEP) mutation manifest by neurodegeneration and renal tubulopathy.	28272532
tRNA recognition by a bacterial tRNA Xm32 modification enzyme from the SPOUT methyltransferase superfamily.	26202969
tRNA transfers to the limelight.	12533506
tRNA-modifying MiaE protein from Salmonella typhimurium is a nonheme diiron monooxygenase.	17679698
tRNAGlu wobble uridine methylation by Trm9 identifies Elongator's key role for zymocin-induced cell death in yeast.	16390459
tRNAHis guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'-3' DNA polymerases.	21059936
tRNAHis guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'-3' DNA polymerases.	21059936
tRNAHis guanylyltransferase (THG1), a unique 3′-5′ nucleotidyl transferase, shares unexpected structural homology with canonical 5′-3′ DNA polymerases.	21059936
tRNAHis maturation: an essential yeast protein catalyzes addition of a guanine nucleotide to the 5' end of tRNAHis.	14633974
TRUB1 is the predominant pseudouridine synthase acting on mammalian mRNA via a predictable and conserved code.	28073919
TtcA a new tRNA-thioltransferase with an Fe-S cluster.	24914049
Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance.	33910046
Two different kinds of interaction modes of deaminase APOBEC3A with single-stranded DNA in solution detected by nuclear magnetic resonance.	34792260
Two proteins that form a complex are required for 7-methylguanosine modification of yeast tRNA.	12403464
U2 snRNA is inducibly pseudouridylated at novel sites by Pus7p and snR81 RNP.	21131909
Ubiquitin-related modifier Urm1 acts as a sulphur carrier in thiolation of eukaryotic transfer RNA.	19145231
Ultrafast Cleavage and Deprotection of Oligonucleotides Synthesis and Use of CAc Derivatives	10.1080/07328319708006236
Underediting of glutamate receptor GluR-B mRNA in malignant gliomas.	11717408
Understanding the Structure, Multimerization, Subcellular Localization and mC Selectivity of a Genomic Mutator and Anti-HIV Factor APOBEC3H.	29491387
Unexpected accumulation of ncm(5)U and ncm(5)S(2) (U) in a trm9 mutant suggests an additional step in the synthesis of mcm(5)U and mcm(5)S(2)U.	21687733
Unexpected expansion of tRNA substrate recognition by the yeast m1G9 methyltransferase Trm10.	23793893
Unique Features of the m6A Methylome in Arabidopsis thaliana	25430002
Unique structural and stabilizing roles for the individual pseudouridine residues in the 1920 region of Escherichia coli 23S rRNA.	10773075
Unveiling structural and functional divergences of bacterial tRNA dihydrouridine synthases: perspectives on the evolution scenario.	29294097
Upregulated METTL3 promotes metastasis of colorectal Cancer via miR-1246/SPRED2/MAPK signaling pathway.	31492150
Uridin-5-oxy acetic acid: a new minor constituent from E. coli valine transfer RNA I.	4910247
Variants in PUS7 Cause Intellectual Disability with Speech Delay, Microcephaly,Short Stature, and Aggressive Behavior.	30526862
Variants in SUP45 and TRM10 underlie natural variation in translation termination efficiency in Saccharomyces cerevisiae.	21829385
Vip1 is a kinase and pyrophosphatase switch that regulates inositol diphosphate signaling.	32303658
Vip1 is a kinase and pyrophosphatase switch that regulates inositol diphosphate signaling.	32303658
Visualizing formation of the active site in the mitochondrial ribosome.	34609277
Visualizing late states of human 40S ribosomal subunit maturation.	29875412
Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.	29245012
Whole exome sequencing identifies a splicing mutation in NSUN2 as a cause of a Dubowitz-like syndrome.	22577224
Widespread occurrence of 5-methylcytosine in human coding and non-coding RNA.	22344696
Wilms' tumor 1-associating protein promotes renal cell carcinoma proliferation by regulating CDK2 mRNA stability.	29482572
Wilms' tumour 1-associating protein inhibits endothelial cell angiogenesis by m6A-dependent epigenetic silencing of desmoplakin in brain arteriovenous malformation.	32281240
Wobble modification deficiency in mutant tRNAs in patients with mitochondrial diseases.	15893315
WTAP Expression Predicts Poor Prognosis in Malignant Glioma Patients.	27370540
WTAP Expression Predicts Poor Prognosis in Malignant Glioma Patients.	27370540
WTAP facilitates progression of hepatocellular carcinoma via m6A-HuR-dependent epigenetic silencing of ETS1.	31438961
X-ray crystal structure of a hypothetical Sua5 protein from Sulfolobus tokodaii strain 7.	18004774
X-ray structure of tRNA pseudouridine synthase TruD reveals an inserted domain with a novel fold	15135053
X-ray structure of tRNA pseudouridine synthase TruD reveals an inserted domain with a novel fold.	15135053
X-ray structures of U2 snRNA-branchpoint duplexes containing conserved pseudouridines.	18435545
YbeA is the m3Psi methyltransferase RlmH that targets nucleotide 1915 in 23S rRNA.	18755835
YccW is the m5C methyltransferase specific for 23S rRNA nucleotide 1962.	18786544
Yeast 18S rRNA dimethylase Dim1p: a quality control mechanism in ribosome synthesis?	9528805
Yeast Kre33 and human NAT10 are conserved 18S rRNA cytosine acetyltransferases that modify tRNAs assisted by the adaptor Tan1/THUMPD1.	25653167
Yeast mitochondrial initiator tRNA is methylated at guanosine 37 by the Trm5-encoded tRNA (guanine-N1-)-methyltransferase.	17652090
Yeast mRNA cap methyltransferase is a 50-kilodalton protein encoded by an essential gene.	7623811
Yeast Nfs1p is involved in thio-modification of both mitochondrial and cytoplasmic tRNAs.	14722066
Yeast Nop2 and Rcm1 methylate C2870 and C2278 of the 25S rRNA, respectively	23913415
Yeast Nop2 and Rcm1 methylate C2870 and C2278 of the 25S rRNA, respectively.	23913415
Yeast NOP2 encodes an essential nucleolar protein with homology to a human proliferation marker.	7806561
Yeast Rrp8p, a novel methyltransferase responsible for m1A 645 base modification of 25S rRNA.	23180764
Yeast serine isoacceptor tRNAs: variations of their content as a function of growth conditions and primary structure of the minor tRNA(Ser)GCU.	8033992
Yeast targets for mRNA methylation.	20421205
Yeast Trm7 interacts with distinct proteins for critical modifications of the tRNAPhe anticodon loop.	22912484
YebU is a m5C methyltransferase specific for 16 S rRNA nucleotide 1407.	16678201
YgdE is the 2'-O-ribose methyltransferase RlmM specific for nucleotide C2498 in bacterial 23S rRNA.	19400805
YhiQ Is RsmJ, the Methyltransferase Responsible for Methylation of G1516 in 16S rRNA of E. coli.	22079366
YibK is the 2'-O-methyltransferase TrmL that modifies the wobble nucleotide in Escherichia coli tRNA(Leu) isoacceptors.	20855540
YrdC exhibits properties expected of a subunit for a tRNA threonylcarbamoyl transferase.	21775474
YTH domain family 2 orchestrates epithelial-mesenchymal transition/proliferation dichotomy in pancreatic cancer cells.	29135329
YTH domain family 2 promotes lung cancer cell growth by facilitating6-phosphogluconate dehydrogenase mRNA translation.	31504235
YTHDF1 Regulates Tumorigenicity and Cancer Stem Cell-Like Activity in Human Colorectal Carcinoma	31131257
YTHDF1 Regulates Tumorigenicity and Cancer Stem Cell-Like Activity in Human Colorectal Carcinoma.	31131257
YTHDF2 reduction fuels inflammation and vascular abnormalization in hepatocellular carcinoma.	31735169
YTHDF2 suppresses cell proliferation and growth via destabilizing the EGFR mRNA inhepatocellular carcinoma.	30423408
Zipper head mechanism of telomere synthesis by human telomerase.	34782750


"NAD-capQ" detection and quantitation of NAD caps.
1 METTL8 is required for 3-methylcytosine modification in human mitochondrial tRNAs
1,4,9-Triazaspiro[5.5]undecan-2-one Derivatives as Potent and Selective METTL3 Inhibitors.
1.92 Angstrom Zinc-Free APOBEC3F Catalytic Domain Crystal Structure.
1.92 Angstrom Zinc-Free APOBEC3F Catalytic Domain Crystal Structure.
15N-labeled tRNA. Identification of 4-thiouridine in Escherichia coli tRNASer1 and tRNATyr2 by 1H-15N two-dimensional NMR spectroscopy.
16S ribosomal RNA pseudouridine synthase RsuA of Escherichia coli: deletion, mutation of the conserved Asp102 residue, and sequence comparison among all other pseudouridine synthases.
2'-O-Methyl-5-hydroxymethylcytidine: A Second Oxidative Derivative of 5-Methylcytidine in RNA.
2'-O-methylation of the mRNA cap protects RNAs from decapping and degradation by DXO
2'-O-ribose methylation of cap2 in human: function and evolution in a horizontally mobile family.
2′-O-Methyl Thiomethyl Modifications in Hammerhead Ribozymes
3-(3-amino-3-carboxypropyl)-5,6-Dihydrouridine is one of two novel post-transcriptional modifications in tRNA(Lys) (UUU) from Trypanosoma brucei.
4-Demethylwyosine synthase from Pyrococcus abyssi is a radical-S-adenosyl-L-methionine enzyme with an additional [4Fe-4S](+2) cluster that interacts with the pyruvate co-substrate.
5' End Nicotinamide Adenine Dinucleotide Cap in Human Cells Promotes RNA Decay through DXO-Mediated deNADding.
5-methoxyuridine: a new minor constituent located in the first position of the anticodon of tRNAAla, tRNAThr, and tRNAVal from Bacillus subtilis.
5-methylcytosine in RNA: detection, enzymatic formation and biological functions.
5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs
7-Methylguanosine diphosphate (m(7)GDP) is not hydrolyzed but strongly bound by decapping scavenger (dcpS) enzymes and potently inhibits their activity.
90 S pre-ribosome transformation into the primordial 40 S subunit.
[Knockdown of YTH N(6)-methyladenosine RNA binding protein 2 (YTHDF2) inhibitsproliferation and promotes apoptosis in MGC-803 gastric cancer cells].
A bimodular nuclear localization signal assembled via an extended double-stranded RNA-binding domain acts as an RNA-sensing signal for transportin 1.
A Bump-Hole Approach for Directed RNA Editing.
A capping-independent function of MePCE in stabilizing 7SK snRNA and facilitating the assembly of 7SK snRNP.
A catalytic intermediate and several flavin redox states stabilized by folate-dependent tRNA methyltransferase from Bacillus subtilis.
A chemical screen for biological small molecule-RNA conjugates reveals CoA-linked RNA.
A cluster of methylations in the domain IV of 25S rRNA is required for ribosome stability.
A common variant in the FTO gene is associated with body mass index and predisposesto childhood and adult obesity.
A commonly carried allele of the obesity-related FTO gene is associated with reducedbrain volume in the healthy elderly.
A Complement to the Modern Crystallographer'S Toolbox: Caged Gadolinium Complexes with Versatile Binding Modes.
A complete landscape of post-transcriptional modifications in mammalian mitochondrial tRNAs.
A conserved family of Saccharomyces cerevisiae synthases effects dihydrouridine modification of tRNA.
A conserved modified wobble nucleoside (mcm5s2U) in lysyl-tRNA is required for viability in yeast.
A cyclic form of N(6)-threonylcarbamoyladenosine as a widely distributed tRNA hypermodification.
A cytidine deaminase edits C to U in transfer RNAs in Archaea
A cytidine deaminase edits C to U in transfer RNAs in Archaea.
A disease-causing point mutation in human mitochondrial tRNAMet rsults in tRNA misfolding leading to defects in translational initiation and elongation.
A disrupted RNA editing balance mediated by ADARs (Adenosine DeAminases that act on RNA) in human hepatocellular carcinoma.
A distinct assembly pathway of the human 39S late pre-mitoribosome
A domain of the actin binding protein Abp140 is the yeast methyltransferase responsible for 3-methylcytidine modification in the tRNA anti-codon loop.
A dual role of human tRNA methyltransferase hTrmt13 in regulating translation and transcription
A dual-specificity pseudouridine synthase: an Escherichia coli synthase purified and cloned on the basis of its specificity for psi 746 in 23S RNA is also specific for psi 32 in tRNA(phe).
A Facile Synthesis of the Phosphoramidites of 2-N-Methyl-2′- deoxy (or 2′-O-allyl)-ψ-isocytidine, 1, 3-Dimethyl-2′-deoxy-ψ-uridine and N1- Methyl-2′-O-allyl-ψ-uridine as Synthons Suitable for Oligonuc
A fluorescence assay for phenylalanine transfer RNA.
A functional proteomics approach links the ubiquitin-related modifier Urm1 to a tRNA modification pathway.
A gain of function mutation in a protein mediates production of novel modified nucleosides.
A Genome-wide CRISPR Death Screen Identifies Genes Essential for Oxidative Phosphorylation.
A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae.
A genome-wide screen identifies the evolutionarily conserved KEOPS complex as a telomere regulator.
A High-Throughput Radioactivity-Based Assay for Screening SARS-CoV-2 nsp10-nsp16 Complex.
A homozygous truncating mutation in PUS3 expands the role of tRNA modification in normal cognition.
A human mitochondrial GTP binding protein related to tRNA modification may modulate phenotypic expression of the deafness-associated mitochondrial 12S rRNA mutation.
A human mitochondrial transcription factor is related to RNA adenine methyltransferases and binds S-adenosylmethionine.
A Left-Handed RNA Double Helix Bound by the Zalpha Domain of the RNA-Editing Enzyme ADAR1.
A limited number of pseudouridine residues in the human atac spliceosomal UsnRNAs as compared to human major spliceosomal UsnRNAs
A map of 5-methylcytosine residues in Trypanosoma brucei tRNA revealed by sodium bisulfite sequencing.
A METTL3-METTL14 complex mediates mammalian nuclear RNA N-adenosine methylation.
A minimalist glutamyl-tRNA synthetase dedicated to aminoacylation of the tRNAAsp QUC anticodon.
A mitochondrial rRNA dimethyladenosine methyltransferase in Arabidopsis.
A new function of S-adenosylmethionine: the ribosyl moiety of AdoMet is the precursor of the cyclopentenediol moiety of the tRNA wobble base queuine.
A new mechanism for chloramphenicol, florfenicol and clindamycin resistance: methylation of 23S ribosomal RNA at A2503.
A new RNA synthetic method with a 2'-O-(2-cyanoethoxymethyl) protecting group.
A novel cloverleaf structure found in mammalian mitochondrial tRNA(Ser) (UCN).
A novel human tRNA-dihydrouridine synthase involved in pulmonary carcinogenesis.
A novel link between the biosynthesis of aromatic amino acids and transfer RNA modification in Escherichia coli.
A novel methyltransferase required for the formation of the hypermodified nucleoside wybutosine in eucaryotic tRNA.
A novel minimum ribozyme with oxidoreduction activity.
A novel Nop5-sRNA interaction that is required for efficient archaeal box C/D sRNP formation.
A Novel RNA Editing Sensor Tool and a Specific Agonist Determine Neuronal Protein Expression of RNA-Edited Glycine Receptors and Identify a Genomic APOBEC1 Dimorphism as a New Genetic Risk Factor of Epilepsy.
A novel translational repressor mRNA is edited extensively in livers containingtumors caused by the transgene expression of the apoB mRNA-editing enzyme.
A novel unanticipated type of pseudouridine synthase with homologs in bacteria, archaea, and eukarya.
A paradigm for biological sulfur transfers via persulfide groups: a persulfide-disulfide-thiol cycle in 4-thiouridine biosynthesis.
A paradigm for local conformational control of function in the ribosome: binding of ribosomal protein S19 to Escherichia coli 16S rRNA in the presence of S7 is required for methylation of m2G966 and blocks methylation of m5C967 by their respective methyltransferases.
A previously unidentified activity of yeast and mouse RNA:pseudouridine synthases 1 (Pus1p) on tRNAs.
A primordial RNA modification enzyme: the case of tRNA (m1A) methyltransferase.
A primordial tRNA modification required for the evolution of life?
A pseudouridine synthase module is essential for mitochondrial protein synthesis and cell viability.
A purified selenophosphate-dependent enzyme from Salmonella typhimurium catalyzes the replacement of sulfur in 2-thiouridine residues in tRNAs with selenium.
A role for the universal Kae1/Qri7/YgjD (COG0533) family in tRNA modification.
A second function for pseudouridine synthases: A point mutant of RluD unable to form pseudouridines 1911, 1915, and 1917 in Escherichia coli 23S ribosomal RNA restores normal growth to an RluD-minus strain.
A second type of N7-guanine RNA cap methyltransferase in an unusual locus of a large RNA virus genome.
A single acetylation of 18S rRNA is essential for biogenesis of the small ribosomal subunit in Saccharomyces cerevisiae.
A single methyltransferase YefA (RlmCD) catalyses both m5U747 and m5U1939 modifications in Bacillus subtilis 23S rRNA.
A single zinc ion is sufficient for an active Trypanosoma brucei tRNA editing deaminase.
A small RNA derived from RNA coactivator SRA blocks steroid receptor signaling via inhibition of Pus1p-mediated pseudouridylation of SRA: evidence of a novel RNA binding domain in the N-terminus of steroid receptors.
A specific modification next to the anticodon of phenylalanine transfer ribonucleic acid.
A splice site mutation in the methyltransferase gene FTSJ1 in Xp11.23 is associated with non-syndromic mental retardation in a large Belgian family (MRX9).
A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor ofN6-methyladenosine demethylase FTO.
A structural, phylogenetic, and functional study of 15.5-kD/Snu13 protein binding on U3 small nucleolar RNA.
A subcomplex of human mitochondrial RNase P is a bifunctional methyltransferase--extensive moonlighting in mitochondrial tRNA biogenesis.
A third member of the RNA-specific adenosine deaminase gene family, ADAR3, contains both single- and double-stranded RNA binding domains.
A tRNA methyltransferase paralog is important for ribosome stability and cell division in Trypanosoma brucei.
A truncated aminoacyl-tRNA synthetase modifies RNA.
A U3 snoRNP protein with homology to splicing factor PRP4 and G beta domains is required for ribosomal RNA processing.
A Unique RNA Fold in the Ruma-RNA-Cofactor Ternary Complex Contributes to Substrate Selectivity and Enzymatic Function
A unique RNA Fold in the RumA-RNA-cofactor ternary complex contributes to substrate selectivity and enzymatic function.
A vastly increased chemical variety of RNA modifications that includes a thioacetal structure
A-to-I and C-to-U editing within transfer RNAs.
A-to-I RNA editing of BLCAP lost the inhibition to STAT3 activation in cervicalcancer.
ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.
Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders.
Aberrant RNA homeostasis in amyotrophic lateral sclerosis: potential for newtherapeutic targets?
Abnormality of m6A mRNA Methylation Is Involved in Alzheimer's Disease.
Absolute and relative quantification of RNA modifications via biosynthetic isotopomers.
Acquisition of a bacterial RumA-type tRNA(uracil-54, C5)-methyltransferase by Archaea through an ancient horizontal gene transfer.
Acquisition of the wobble modification in mitochondrial tRNALeu(CUN) bearing the G12300A mutation suppresses the MELAS molecular defect.
Actin-binding protein ABP140 is a methyltransferase for 3-methylcytidine at position 32 of tRNAs in Saccharomyces cerevisiae.
Active site in RrmJ, a heat shock-induced methyltransferase.
Active site mapping and substrate specificity of bacterial Hen1, a manganese-dependent 3' terminal RNA ribose 2'O-methyltransferase.
Active Site of Lysyl-tRNA Synthetase: Structural Studies of the Adenylation Reaction
Acute spinal cord injury persistently reduces R/G RNA editing of AMPA receptors.
ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia.
ADAR2 functions as a tumor suppressor via editing IGFBP7 in esophageal squamous cell carcinoma.
Adenosine-to-inosine RNA editing mediated by ADARs in esophageal squamous cell carcinoma.
Agmatidine, a modified cytidine in the anticodon of archaeal tRNA(Ile), base pairs with adenosine but not with guanosine.
Agmatine-conjugated cytidine in a tRNA anticodon is essential for AUA decoding in archaea.
AI-empowered integrative structural characterization of m 6 A methyltransferase complex.
AID Recognizes Structured DNA for Class Switch Recombination.
AID Recognizes Structured DNA for Class Switch Recombination.
Alanine-scanning mutagenesis of the predicted rRNA-binding domain of ErmC' redefines the substrate-binding site and suggests a model for protein-RNA interactions.
ALKBH1 is an RNA dioxygenase responsible for cytoplasmic and mitochondrial tRNA modifications.
ALKBH5 Inhibits Pancreatic Cancer Motility by Decreasing Long Non-Coding RNA KCNK15-AS1 Methylation.
ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility.
ALKBH5 promotes invasion and metastasis of gastric cancer by decreasing methylation of the lncRNA NEAT1.
ALKBH5-m(6)A-FOXM1 signaling axis promotes proliferation and invasion of lungadenocarcinoma cells under intermittent hypoxia.
ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNA.
Altered adenosine-to-inosine RNA editing in human cancer
Altered editing in cyclic nucleotide phosphodiesterase 8A1 gene transcripts of systemic lupus erythematosus T lymphocytes
Altered Editing of Serotonin 2C Receptor Pre-mRNA in the Prefrontal Cortex of Depressed Suicide Victims
Alternate rRNA secondary structures as regulators of translation
Alternative conformations of the archaeal Nop56/58-fibrillarin complex imply flexibility in box C/D RNPs.
Alternative Conformations of the Archaeal Nop56/58-Fibrillarin Complex Imply Flexibility in Box C/D RNPs.
Alternative splicing and extensive RNA editing of human TPH2 transcripts.
Alternative Tertiary Structure of tRNA for Recognition by a Posttranscriptional Modification Enzyme
Alternative tertiary structure of tRNA for recognition by a posttranscriptional modification enzyme.
Alu-dependent RNA editing of GLI1 promotes malignant regeneration in multiple myeloma.
Aminoacylation of the anticodon stem by a tRNA-synthetase paralog: relic of an ancient code?
AML1-ETO requires enhanced C/D box snoRNA/RNP formation to induce self-renewal and leukaemia.
AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders
An adenosine deaminase that generates inosine at the wobble position of tRNAs.
An adenosine-to-inosine tRNA-editing enzyme that can perform C-to-U deamination of DNA.
An aminoacyl-tRNA synthetase-like protein encoded by the Escherichia coli yadB gene glutamylates specifically tRNAAsp.
An archaeal orthologue of the universal protein Kae1 is an iron metalloprotein which exhibits atypical DNA-binding properties and apurinic-endonuclease activity in vitro.
An arginine-aspartate network in the active site of bacterial TruB is critical for catalyzing pseudouridine formation.
An association study of the m6A genes with major depressive disorder in Chinese Hanpopulation.
An ATP-binding cassette transporter and two rRNA methyltransferases are involved in resistance to avilamycin in the producer organism Streptomyces viridochromogenes Tu57.
An early step in wobble uridine tRNA modification requires the Elongator complex.
An essential function of Saccharomyces cerevisiae RNA triphosphatase Cet1 is to stabilize RNA guanylyltransferase Ceg1 against thermal inactivation.
An essential yeast protein, CBF5p, binds in vitro to centromeres and microtubules.
An extended dsRBD is required for post-transcriptional modification in human tRNAs.
An extended dsRBD is required for post-transcriptional modification in human tRNAs.
An extended structure of the APOBEC3G catalytic domain suggests a unique holoenzyme model
An extensive allelic series of Drosophila kae1 mutants reveals diverse and tissue-specific requirements for t6A biogenesis
An Improved Synthesis of Inosine 3′-Phosphoramidite
An intact Box C sequence in the U3 snRNA is required for binding of fibrillarin, the protein common to the major family of nucleolar snRNPs.
An RNA modification enzyme directly senses reactive oxygen species for translational regulation in Enterococcus faecalis
An RNA-modifying enzyme that governs both the codon and amino acid specificities of isoleucine tRNA.
Analysis of deletion phenotypes and GFP fusions of 21 novel Saccharomyces cerevisiae open reading frames.
Analysis of GTP addition in the reverse (3'-5') direction by human tRNA His guanylyltransferase.
Analysis of pre-mRNA and pre-rRNA processing factor Snu13p structure and mutants.
Analysis of sequence and structural features that identify the B/C motif of U3 small nucleolar RNA as the recognition site for the Snu13p-Rrp9p protein pair.
Analysis of Snu13p mutations reveals differential interactions with the U4 snRNA and U3 snoRNA.
Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Analysis of the function of E. coli 23S rRNA helix-loop 69 by mutagenesis.
Antiviral amphipathic oligo- and polyribonucleotides: analogue development and biological studies.
APOBEC3A is implicated in a novel class of G-to-A mRNA editing in WT1 transcripts.
Aquifex aeolicus Trm1[tRNA (m2(2)G26) methyltransferase] has a novel recognition mechanism of the substrate RNA.
Aquifex aeolicus tRNA (N2,N2-guanine)-dimethyltransferase (Trm1) catalyzes transfer of methyl groups not only to guanine 26 but also to guanine 27 in tRNA.
Arabidopsis N6-methyladenosine methyltransferase FIONA1 regulates floral transition by affecting the splicing of FLC and the stability of floral activators SPL3 and SEP3
Arabidopsis tRNA adenosine deaminase arginine edits the wobble nucleotide of chloroplast tRNAArg(ACG) and is essential for efficient chloroplast translation.
Archaeal Pus10 proteins can produce both pseudouridine 54 and 55 in tRNA.
Archease from Pyrococcus abyssi improves substrate specificity and solubility of a tRNA m5C methyltransferase.
Architecture of the Human Mitochondrial Iron-Sulfur Cluster Assembly Machinery.
Architecture of the yeast Elongator complex.
Architecture of the yeast small subunit processome.
Archtecture of the yeast small subunit processome
Artificial intelligence-assisted cryoEM structure of Bfr2-Lcp5 complex observed in the yeast small subunit processome
Assay of both activities of the bifunctional tRNA-modifying enzyme MnmC reveals a kinetic basis for selective full modification of cmnm5s2U to mnm5s2U.
Assembly of the archaeal box C/D sRNP can occur via alternative pathways and requires temperature-facilitated sRNA remodeling.
Assignment of 2'-O-methyltransferases to Modification Sites on the Mammalian Mitochondrial Large Subunit 16S rRNA.
Association between obesity-related gene FTO and ADHD.
Asymmetric dimerization of adenosine deaminase acting on RNA facilitates substrate recognition.
Atomic structure of a folate/FAD-dependent tRNA T54 methyltransferase
Atomic structure of a folate/FAD-dependent tRNA T54 methyltransferase
Atomic structure of a folate/FAD-dependent tRNA T54 methyltransferase.
Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine.
Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine.
Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine.
Backbone resonance assignments of the 48 kDa dimeric putative 18S rRNA-methyltransferase Nep1 from Methanocaldococcus jannaschii.
Bacterial Hen1 is a 3' terminal RNA ribose 2'-O-methyltransferase component of a bacterial RNA repair cassette.
Base methylations in the double-stranded RNA by a fused methyltransferase bearing unwinding activity.
Binding Induced RNA Conformational Changes Control Substrate Recognition and Catalysis by the Thiostrepton-resistance Methyltransferase (Tsr).
Binding of adenosine-based ligands to the MjDim1 rRNA methyltransferase: implications for reaction mechanism and drug design.
Binding of adenosine-based ligands to the MjDim1 rRNA methyltransferase: implications for reaction mechanism and drug design.
Binding of adenosine-based ligands to the MjDim1 rRNA methyltransferase: implications for reaction mechanism and drug design.
Binding of L7Ae protein to the K-turn of archaeal snoRNAs: a shared RNA binding motif for C/D and H/ACA box snoRNAs in Archaea.
Binding of the human Prp31 Nop domain to a composite RNA-protein platform in U4 snRNP.
Binding of the human Prp31 Nop domain to a composite RNA-protein platform in U4 snRNP.
Biochemical and Computational Analysis of the Substrate Specificities of Cfr and RlmN Methyltransferases
Biochemical and genetic analysis of RNA cap guanine-N2 methyltransferases from Giardia lamblia and Schizosaccharomyces pombe.
Biochemical and structural characterization of a thermostable Dps protein with His-type ferroxidase centers and outer metal-binding sites.
Biochemical and structural insights into the mechanisms of SARS coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex.
Biochemical characterization of mRNA capping enzyme from Faustovirus
Biogenesis and growth phase-dependent alteration of 5-methoxycarbonylmethoxyuridine in tRNA anticodons
Biogenesis and intranuclear trafficking of human box C/D and H/ACA RNPs.
Biogenesis of 2-agmatinylcytidine catalyzed by the dual protein and RNA kinase TiaS.
Biogenesis of glutaminyl-mt tRNAGln in human mitochondria.
Bioinformatic analyses of the tRNA: (guanine 26, N2,N2)-dimethyltransferase (Trm1) family.
Biosynthesis and function of tRNA modifications in Archaea.
Biosynthesis of 7-deazaguanosine-modified tRNA nucleosides: a new role for GTP cyclohydrolase I.
Biosynthesis of a hypermodified nucleotide in Saccharomyces carlsbergensis 17S and HeLa-cell 18S ribosomal ribonucleic acid.
Biosynthesis of archaeosine, a novel derivative of 7-deazaguanosine specific to archaeal tRNA, proceeds via a pathway involving base replacement on the tRNA polynucleotide chain.
Biosynthesis of selenophosphate.
Biosynthesis of threonylcarbamoyl adenosine (t6A), a universal tRNA nucleoside.
Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA.
Biosynthesis of wyosine derivatives in tRNA(Phe) of Archaea: role of a remarkable bifunctional tRNA(Phe):m1G/imG2 methyltransferase.
Biosynthesis of wyosine derivatives in tRNA: an ancient and highly diverse pathway in Archaea.
Box C/D guide RNAs recognize a maximum of 10 nt of substrates
Box C/D guide RNAs recognize a maximum of 10 nt of substrates
Box C/D snoRNP catalysed methylation is aided by additional pre-rRNA base-pairing.
Box H/ACA small ribonucleoproteins.
Bud23 methylates G1575 of 18S rRNA and is required for efficient nuclear export of pre-40S subunits.
C-->U editing of neurofibromatosis 1 mRNA occurs in tumors that express both thetype II transcript and apobec-1, the catalytic subunit of the apolipoprotein BmRNA-editing enzyme.
Caenorhabditis elegans pseudouridine synthase 1 activity in vivo: tRNA is a substrate, but not U2 small nuclear RNA.
cAMP-dependent transcription of the human CYP21B (P-450C21) gene requires a cis-regulatory element distinct from the consensus cAMP-regulatory element.
Cap methyltransferase selective binding and methylation of GpppG-RNA are stimulated by importin-alpha.
Cap-specific terminal -methylation of RNA by an RNA polymerase II-associated methyltransferase.
Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II-associated methyltransferase.
Cap-specific, terminal N-methylation by a mammalian mAm methyltransferase.
Catalysis by the second class of tRNA(m1G37) methyl transferase requires a conserved proline.
Cbf5p, the putative pseudouridine synthase of H/ACA-type snoRNPs, can form a complex with Gar1p and Nop10p in absence of Nhp2p and box H/ACA snoRNAs.
CDK13 RNA Over-Editing Mediated by ADAR1 Associates with Poor Prognosis of Hepatocellular Carcinoma Patients.
cDNA cloning and sequencing of human fibrillarin, a conserved nucleolar protein recognized by autoimmune antisera.
Cfr and RlmN contain a single [4Fe-4S] cluster, which directs two distinct reactivities for S-adenosylmethionine: methyl transfer by SN2 displacement and radical generation.
Changes in conformational equilibria regulate the activity of the Dcp2 decapping enzyme.
Changes of N6-methyladenosine modulators promote breast cancer progression.
Chapter 21 - Aberrant AID Expression by Pathogen Infection
Characterization and structure of the Aquifex aeolicus protein DUF752: a bacterial tRNA-methyltransferase (MnmC2) functioning without the usually fused oxidase domain (MnmC1)
Characterization and structure of the Aquifex aeolicus protein DUF752: a bacterial tRNA-methyltransferase (MnmC2) functioning without the usually fused oxidase domain (MnmC1).
Characterization of a B. subtilis minor isoleucine tRNA deduced from tDNA having a methionine anticodon CAT.
Characterization of a whole set of tRNA molecules in an aerobic hyper-thermophilic Crenarchaeon, Aeropyrum pernix K1.
Characterization of GTPase activity of TrmE, a member of a novel GTPase superfamily, from Thermotoga maritima.
Characterization of hMTr1, a human Cap1 2'-O-ribose methyltransferase.
Characterization of human, Schizosaccharomyces pombe, and Candida albicans mRNA cap methyltransferases and complete replacement of the yeast capping apparatus by mammalian enzymes.
Characterization of novel human Intragenic Antimicrobial Peptides, incorporation and release studies from ureasil-polyether hybrid matrix
Characterization of the 23 S ribosomal RNA m5U1939 methyltransferase from Escherichia coli.
Characterization of the human tRNA-guanine transglycosylase: confirmation of the heterodimeric subunit structure.
Characterization of two homologous 2'-O-methyltransferases showing different specificities for their tRNA substrates.
Characterization of Two Homologous 2'-O-Methyltransferases Showing Different Specificities for Their tRNA Substrates.
Characterization of Two Homologous 2'-O-Methyltransferases Showing Different Specificities for Their tRNA Substrates.
Characterization of yeast protein Deg1 as pseudouridine synthase (Pus3) catalyzing the formation of psi 38 and psi 39 in tRNA anticodon loop.
Chemical Approach for the Study of the ‘Kissing Complex’ of Moloney murine leukaemia Virus
Chemical incorporation of 1‑methyladenosine into oligonucleotides
Chemical synthesis of a biologically active natural tRNA with its minor bases.
Chemical synthesis of RNA including 5-taurinomethyluridine
Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediate
Chloroplast development at low temperatures requires a homolog of DIM1, a yeast gene encoding the 18S rRNA dimethylase.
Chromosome 8 BAC array comparative genomic hybridization and expression analysis identify amplification and overexpression of TRMT12 in breast cancer.
Cloning and characterization of a p53-related protein kinase expressed in interleukin-2-activated cytotoxic T-cells, epithelial tumor cell lines, and the testes.
Cloning and characterization of an aminoglycoside resistance determinant from Micromonospora zionensis.
Cloning and characterization of the 23S RNA pseudouridine 2633 synthase from Bacillus subtilis.
Cloning and characterization of the Schizosaccharomyces pombe tRNA:pseudouridine synthase Pus1p.
Cloning and characterization of three human cDNAs encoding mRNA (guanine-7-)-methyltransferase, an mRNA cap methylase.
Cloning and characterization of tRNA (m1A58) methyltransferase (TrmI) from Thermus thermophilus HB27, a protein required for cell growth at extreme temperatures.
Cloning and characterization of two human cDNAs encoding the mRNA capping enzyme.
Cloning and mapping of a human novel cDNA (NHP2L1) that encodes a protein highly homologous to yeast nuclear protein NHP2.
Cloning and restriction mapping of the trmA gene coding for transfer ribonucleic acid (5-methyluridine)-methyltransferase in Escherichia coli K-12.
Cloning of a human tRNA isopentenyl transferase.
Cloning of an Apobec-1-binding protein that also interacts with apolipoprotein B mRNA and evidence for its involvement in RNA editing
Cocrystal structure of a tRNA Psi55 pseudouridine synthase: nucleotide flipping by an RNA-modifying enzyme.
Common thiolation mechanism in the biosynthesis of tRNA thiouridine and sulphur-containing cofactors.
Comparative analysis of the 15.5kD box C/D snoRNP core protein in the primitive eukaryote Giardia lamblia reveals unique structural and functional features.
Comparative analysis of the 15.5kD box C/D snoRNP core protein in the primitive eukaryote Giardia lamblia reveals unique structural and functional features.
Complete chemical structures of human mitochondrial tRNAs
Comprehensive phylogenetic analysis of evolutionarily conserved rRNA adenine dimethyltransferase suggests diverse bacterial contributions to the nucleus-encoded plastid proteome.
Conformational change of pseudouridine 55 synthase upon its association with RNA substrate.
Conformational communication mediates the reset step in t6A biosynthesis.
Conformational proofreading of distant 40S ribosomal subunit maturation events by a long-range communication mechanism.
Conformational Stability Adaptation of a Double-Stranded RNA-Binding Domain to Transfer RNA Ligand.
Conformational Switch Regulates the DNA Cytosine Deaminase Activity of Human APOBEC3B.
Conformational Switch Regulates the DNA Cytosine Deaminase Activity of Human APOBEC3B.
Conformational switches control early maturation of the eukaryotic small ribosomal subunit.
Conservation of an intricate circuit for crucial modifications of the tRNAPhe anticodon loop in eukaryotes.
Conservation of structure and mechanism by Trm5 enzymes.
Conserved amino acids in each subunit of the heteroligomeric tRNA m1A58 Mtase from Saccharomyces cerevisiae contribute to tRNA binding.
Conserved cysteine residues of GidA are essential for biogenesis of 5-carboxymethylaminomethyluridine at tRNA anticodon
Conserved cysteine residues of GidA are essential for biogenesis of 5-carboxymethylaminomethyluridine at tRNA anticodon
Conserved cysteine residues of GidA are essential for biogenesis of 5-carboxymethylaminomethyluridine at tRNA anticodon.
Conserved network of proteins essential for bacterial viability.
Conserved P-loop GTPases of unknown function in bacteria: an emerging and vital ensemble in bacterial physiology.
Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis.
Control of catalytic cycle by a pair of analogous tRNA modification enzymes.
Control of human potassium channel inactivation by editing of a small mRNA hairpin.
Control of substrate specificity by a single active site residue of the KsgA methyltransferase.
Control of Substrate Specificity by a Single Active Site Residue of the KsgA Methyltransferase.
Coordinate expression of NADPH-dependent flavin reductase, Fre-1, and Hint-related 7meGMP-directed hydrolase, DCS-1.
Coupling of N7-methyltransferase and 3'-5' exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading.
Covalent Intermediate in the Catalytic Mechanism of the Radical S-Adenosyl-l-methionine Methyl Synthase RlmN Trapped by Mutagenesis.
Critical residues for cofactor binding and catalytic activity in the aminoglycoside resistance methyltransferase Sgm.
Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states.
Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation
Cryo-EM Structure of an Extended SARS-CoV-2 Replication and Transcription Complex Reveals an Intermediate State in Cap Synthesis.
Cryo-EM Structure of an Extended SARS-CoV-2 Replication and Transcription Complex Reveals an Intermediate State in Cap Synthesis.
Cryo-EM structure of the EBV ribonucleotide reductase BORF2 and mechanism of APOBEC3B inhibition.
Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution.
Cryo-EM structures of human m6A writer complexes.
CryoEM structure of the low-complexity domain of hnRNPA2 and its conversion to pathogenic amyloid
Crystal and solution structures of methyltransferase RsmH provide basis for methylation of C1402 in 16S rRNA.
Crystal and solution structures of methyltransferase RsmH provide basis for methylation of C1402 in 16S rRNA.
Crystal structure and cap binding analysis of the methyltransferase of langat virus
Crystal structure and functional analysis of Dcp2p from Schizosaccharomyces pombe
Crystal Structure and Functional Analysis of the Sars-Coronavirus RNA CAP 2'-O-Methyltransferase Nsp10/Nsp16 Complex.
Crystal structure and mutational study of a unique SpoU family archaeal methylase that forms 2'-O-methylcytidine at position 56 of tRNA
Crystal structure and mutational study of a unique SpoU family archaeal methylase that forms 2'-O-methylcytidine at position 56 of tRNA.
Crystal structure and RNA binding properties of the RNA recognition motif (RRM) and AlkB domains in human AlkB homolog 8 (ABH8), an enzyme catalyzing tRNA hypermodification.
Crystal structure and RNA binding properties of the RNA recognition motif (RRM) and AlkB domains in human AlkB homolog 8 (ABH8), an enzyme catalyzing tRNA hypermodification.
Crystal structure and RNA binding properties of the RNA recognition motif (RRM) and AlkB domains in human AlkB homolog 8 (ABH8), an enzyme catalyzing tRNA hypermodification.
Crystal structure of a Cbf5-Nop10-Gar1 complex and implications in RNA-guided pseudouridylation and dyskeratosis congenita.
Crystal structure of a fibrillarin homologue from Methanococcus jannaschii, a hyperthermophile, at 1.6 A resolution.
Crystal structure of a fibrillarin homologue from Methanococcus jannaschii, a hyperthermophile, at 1.6 A resolution.
Crystal structure of a junction between B-DNA and Z-DNA reveals two extruded bases.
Crystal structure of a junction between two Z-DNA helices.
Crystal structure of a novel JmjC-domain-containing protein, TYW5, involved in tRNA modification.
Crystal structure of a novel JmjC-domain-containing protein, TYW5, involved in tRNA modification.
Crystal structure of a novel JmjC-domain-containing protein, TYW5, involved in tRNA modification.
Crystal structure of a Y-box binding protein 1 (YB-1)-RNA complex reveals key features and residues interacting with RNA.
Crystal structure of an H/ACA box ribonucleoprotein particle
Crystal structure of an RluF-RNA complex: a base-pair rearrangement is the key to selectivity of RluF for U2604 of the ribosome.
Crystal structure of an RluF-RNA complex: a base-pair rearrangement is the key to selectivity of RluF for U2604 of the ribosome.
Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity.
Crystal structure of archaeal tRNA(m(1)G37)methyltransferase aTrm5.
Crystal structure of archaeal tRNA(m(1)G37)methyltransferase aTrm5.
Crystal structure of archaeosine tRNA-guanine transglycosylase.
Crystal structure of archaeosine tRNA-guanine transglycosylase.
Crystal structure of Bacillus anthracis ThiI, a tRNA-modifying enzyme containing the predicted RNA-binding THUMP domain.
Crystal structure of Bacillus subtilis S-adenosylmethionine:tRNA ribosyltransferase-isomerase.
Crystal structure of Bacillus subtilis TrmB, the tRNA (m7G46) methyltransferase.
Crystal structure of Bacillus subtilis TrmB, the tRNA (m7G46) methyltransferase.
Crystal structure of DNA cytidine deaminase ABOBEC3G catalytic deamination domain suggests a binding mode of full-length enzyme to single-stranded DNA
Crystal structure of elongator subcomplex Elp4-6
Crystal structure of ErmC', an rRNA methyltransferase which mediates antibiotic resistance in bacteria.
Crystal structure of ErmC', an rRNA methyltransferase which mediates antibiotic resistance in bacteria.
Crystal structure of ErmE - 23S rRNA methyltransferase in macrolide resistance.
Crystal structure of ErmE - 23S rRNA methyltransferase in macrolide resistance.
Crystal structure of glutamyl-queuosine tRNAAsp synthetase complexed with L-glutamate: structural elements mediating tRNA-independent activation of glutamate and glutamylation of tRNAAsp anticodon.
Crystal Structure of Glutamyl-Queuosine Trnaasp Synthetase Complexed with L-Glutamate: Structural Elements Mediating tRNA-Independent Activation of Glutamate and Glutamylation of Trnaasp Anticodon.
Crystal structure of human ABAD/HSD10 with a bound inhibitor: implications for design of Alzheimer's disease therapeutics
Crystal structure of human cytoplasmic tRNAHis-specific 5'-monomethylphosphate capping enzyme.
Crystal structure of human diphosphoinositol phosphatase 1
Crystal structure of human diphosphoinositol phosphatase 1.
Crystal structure of human METTL6, the m3C methyltransferase
Crystal structure of human Pus10, a novel pseudouridine synthase.
Crystal Structure of Human Pus10, a Novel Pseudouridine Synthase.
Crystal structure of human YTHDC2 YTH domain.
Crystal structure of IscA, an iron-sulfur cluster assembly protein from Escherichia coli.
Crystal structure of IscA, an iron-sulfur cluster assembly protein from Escherichia coli.
Crystal Structure of IscS, a Cysteine Desulfurase from Escherichia coli
Crystal structure of IscS, a cysteine desulfurase from Escherichia coli.
Crystal structure of KsgA, a universally conserved rRNA adenine dimethyltransferase in Escherichia coli
Crystal structure of KsgA, a universally conserved rRNA adenine dimethyltransferase in Escherichia coli.
Crystal structure of Methanocaldococcus jannaschii Trm4 complexed with sinefungin.
Crystal structure of Mj1640/DUF358 protein reveals a putative SPOUT-class RNA methyltransferase
Crystal structure of Mj1640/DUF358 protein reveals a putative SPOUT-class RNA methyltransferase.
Crystal Structure of Non-Structural Protein 10 from Severe Acute Respiratory Syndrome Coronavirus-2.
Crystal structure of pseudouridine synthase RluA: indirect sequence readout through protein-induced RNA structure
Crystal structure of pseudouridine synthase RluA: indirect sequence readout through protein-induced RNA structure.
Crystal structure of QueC from Bacillus subtilis: an enzyme involved in preQ1 biosynthesis.
Crystal structure of RlmAI: implications for understanding the 23S rRNA G745/G748-methylation at the macrolide antibiotic-binding site.
Crystal structure of RlmAI: implications for understanding the 23S rRNA G745/G748-methylation at the macrolide antibiotic-binding site.
Crystal Structure of Rlmm, the 2'O-Ribose Methyltransferase for C2498 of Escherichia Coli 23S Rrna
Crystal Structure of RNA 3'-Terminal Phosphate Cyclase, a Ubiquitous Enzyme with Unusual Topology
Crystal structure of RumA, an iron-sulfur cluster containing E. coli ribosomal RNA 5-methyluridine methyltransferase.
Crystal Structure of Ruma, an Iron-Sulfur Cluster Containing E. Coli Ribosomal RNA 5-Methyluridine Methyltransferase.
Crystal structure of Rv2118c: an AdoMet-dependent methyltransferase from Mycobacterium tuberculosis H37Rv.
Crystal structure of Rv2118c: an AdoMet-dependent methyltransferase from Mycobacterium tuberculosis H37Rv.
Crystal structure of S-adenosylmethionine:tRNA ribosyltransferase-isomerase (QueA) from Thermotoga maritima at 2.0 A resolution reveals a new fold.
Crystal structure of SARS-CoV-2 nsp10 bound to nsp14-ExoN domain reveals an exoribonuclease with both structural and functional integrity.
Crystal structure of SARS-CoV-2 nsp10 bound to nsp14-ExoN domain reveals an exoribonuclease with both structural and functional integrity.
Crystal structure of Staphylococcus aureus tRNA adenosine deaminase TadA in complex with RNA.
Crystal structure of Sulfolobus tokodaii Sua5 complexed with L-threonine and AMPPNP.
Crystal structure of the ancient, Fe-S scaffold IscA reveals a novel protein fold.
Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications.
Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications.
Crystal structure of the apo forms of psi 55 tRNA pseudouridine synthase from Mycobacterium tuberculosis: a hinge at the base of the catalytic cleft.
Crystal Structure of the APOBEC3G Catalytic Domain Reveals Potential Oligomerization Interfaces.
Crystal Structure of the Avilamycin Resistance-Conferring Methyltransferase Avira from Streptomyces Viridochromogenes
Crystal structure of the avilamycin resistance-conferring methyltransferase AviRa from Streptomyces viridochromogenes.
Crystal structure of the bifunctional tRNA modification enzyme MnmC from Escherichia coli
Crystal structure of the bifunctional tRNA modification enzyme MnmC from Escherichia coli.
Crystal structure of the catalytic domain of HIV-1 restriction factor APOBEC3G in complex with ssDNA.
Crystal structure of the catalytic domain of RluD, the only rRNA pseudouridine synthase required for normal growth of Escherichia coli
Crystal structure of the catalytic domain of RluD, the only rRNA pseudouridine synthase required for normal growth of Escherichia coli.
Crystal structure of the dimeric Urm1 from the yeast Saccharomyces cerevisiae
Crystal Structure of the DNA Cytosine Deaminase APOBEC3F: The Catalytically Active and HIV-1 Vif-Binding Domain.
Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain.
Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain.
Crystal structure of the Escherichia coli 23S rRNA:m5C methyltransferase RlmI (YccW) reveals evolutionary links between RNA modification enzymes
Crystal structure of the Escherichia coli 23S rRNA:m5C methyltransferase RlmI (YccW) reveals evolutionary links between RNA modification enzymes.
Crystal structure of the Escherichia coli glucose-inhibited division protein B (GidB) reveals a methyltransferase fold.
Crystal structure of the Escherichia coli glucose-inhibited division protein B (GidB) reveals a methyltransferase fold.
Crystal structure of the FTO protein reveals basis for its substrate specificity
Crystal structure of the FTO protein reveals basis for its substrate specificity.
Crystal structure of the highly divergent pseudouridine synthase TruD reveals a circular permutation of a conserved fold.
Crystal structure of the highly divergent pseudouridine synthase TruD reveals a circular permutation of a conserved fold.
Crystal structure of the human PRPK-TPRKB complex.
Crystal Structure of the Human tRNA Guanine Transglycosylase Catalytic Subunit QTRT1.
Crystal Structure of the Human tRNA Guanine Transglycosylase Catalytic Subunit QTRT1.
Crystal Structure of the Human tRNA m(1)A58 Methyltransferase-tRNA3(Lys) Complex: Refolding of Substrate tRNA Allows Access to the Methylation Target.
Crystal Structure of the Human tRNA m(1)A58 Methyltransferase-tRNA3(Lys) Complex: Refolding of Substrate tRNA Allows Access to the Methylation Target.
Crystal Structure of the Human tRNA mA58 Methyltransferase-tRNA Complex: Refolding of Substrate tRNA allows Access to the Methylation Target.
Crystal Structure of the Nosiheptide-Resistance Methyltransferase of Streptomyces actuosus
Crystal structure of the radical SAM enzyme catalyzing tricyclic modified base formation in tRNA.
Crystal structure of the RluD pseudouridine Synthase catalytic module, an enzyme that modifies 23S rRNA and is essential for normal cell growth of Escherichia coli
Crystal structure of the RluD pseudouridine synthase catalytic module, an enzyme that modifies 23S rRNA and is essential for normal cell growth of Escherichia coli.
Crystal structure of the RNA demethylase ALKBH5 from zebrafish.
Crystal Structure of the Spliceosomal 15.5Kd Protein Bound to a U4 Snrna Fragment
Crystal structure of the spliceosomal 15.5kD protein bound to a U4 snRNA fragment.
Crystal structure of the Thermus thermophilus 16 S rRNA methyltransferase RsmC in complex with cofactor and substrate guanosine.
Crystal structure of the transcription factor sc-mtTFB offers insights into mitochondrial transcription.
Crystal structure of the transcription factor sc-mtTFB offers insights into mitochondrial transcription.
Crystal structure of the Tum1 protein from the yeast Saccharomyces cerevisiae.
Crystal structure of the two-subunit tRNA m(1)A58 methyltransferase TRM6-TRM61 from Saccharomyces cerevisiae.
Crystal structure of the YTH domain of YTHDF2 reveals mechanism for recognition of N6-methyladenosine.
Crystal structure of the Zalpha domain of the human editing enzyme ADAR1 bound to left-handed Z-DNA.
Crystal Structure of Thermus thermophilus tRNA m(1)A(58) Methyltransferase and Biophysical Characterization of Its Interaction with tRNA.
Crystal structure of Thermus thermophilus tRNA m1A58 methyltransferase and biophysical characterization of its interaction with tRNA.
Crystal structure of tRNA adenosine deaminase (TadA) from Aquifex aeolicus.
Crystal structure of tRNA m1G9 methyltransferase Trm10: insight into the catalytic mechanism and recognition of tRNA substrate
Crystal structure of tRNA m1G9 methyltransferase Trm10: insight into the catalytic mechanism and recognition of tRNA substrate.
Crystal Structure of tRNA N(2),N(2)-Guanosine Dimethyltransferase Trm1 from Pyrococcus horikoshii
Crystal Structure of tRNA N(2),N(2)-Guanosine Dimethyltransferase Trm1 from Pyrococcus horikoshii
Crystal structure of tRNA N2,N2-guanosine dimethyltransferase Trm1 from Pyrococcus horikoshii.
Crystal structure of tRNA pseudouridine synthase TruA from Thermus thermophilus HB8.
Crystal structure of tRNA-guanine transglycosylase: RNA modification by base exchange.
Crystal structure of TruD, a novel pseudouridine synthase with a new protein fold
Crystal structure of TruD, a novel pseudouridine synthase with a new protein fold.
Crystal structure of YecO from Haemophilus influenzae (HI0319) reveals a methyltransferase fold and a bound S-adenosylhomocysteine.
Crystal structure of YecO from Haemophilus influenzae (HI0319) reveals a methyltransferase fold and a bound S-adenosylhomocysteine.
Crystal structures of human DcpS in ligand-free and m7GDP-bound forms suggest a dynamic mechanism for scavenger mRNA decapping.
Crystal Structures of Human RNA Demethylase Alkbh5 Reveal Basis for Substrate Recognition.
Crystal structures of the bifunctional tRNA methyltransferase Trm5a
Crystal structures of the catalytic domains of pseudouridine synthases RluC and RluD from Escherichia coli
Crystal structures of the catalytic domains of pseudouridine synthases RluC and RluD from Escherichia coli.
Crystal structures of the conserved tRNA-modifying enzyme GidA: implications for its interaction with MnmE and substrate.
Crystal structures of the conserved tRNA-modifying enzyme GidA: implications for its interaction with MnmE and substrate
Crystal structures of the conserved tRNA-modifying enzyme GidA: implications for its interaction with MnmE and substrate
Crystal structures of the Gon7/Pcc1 and Bud32/Cgi121 complexes provide a model for the complete yeast KEOPS complex.
Crystal structures of the human RNA demethylase Alkbh5 reveal basis for substrate recognition
Crystal structures of the human RNA demethylase Alkbh5 reveal basis for substrate recognition
Crystal structures of the tRNA:m2G6 methyltransferase Trm14/TrmN from two domains of life.
Crystal structures of the tRNA:m2G6 methyltransferase Trm14/TrmN from two domains of life.
Crystal structures of tRNA-guanine transglycosylase (TGT) in complex with novel and potent inhibitors unravel pronounced induced-fit adaptations and suggest dimer formation upon substrate binding.
Crystallization and characterization of a fragment of pseudouridine synthase RluC from Escherichia coli.
Crystallization and preliminary crystallographic analysis of nosiheptide-resistance methyltransferase from Streptomyces actuosus in complex with SAM.
Crystallization and preliminary X-ray characterization of queD from Bacillus subtilis, an enzyme involved in queuosine biosynthesis.
Crystallization and preliminary X-ray characterization of the nitrile reductase QueF: a queuosine-biosynthesis enzyme.
Crystallographic snapshots of eukaryotic dimethylallyltransferase acting on tRNA: insight into tRNA recognition and reaction mechanism.
Cysteine of sequence motif VI is essential for nucleophilic catalysis by yeast tRNA m5C methyltransferase.
Cytosine-5 RNA methylation links protein synthesis to cell metabolism.
DcpS as a therapeutic target for spinal muscular atrophy.
DcpS can act in the 5'-3' mRNA decay pathway in addition to the 3'-5' pathway.
Decapping Enzyme NUDT12 Partners with BLMH for Cytoplasmic Surveillance of NAD-Capped RNAs.
Decapping reaction of mRNA requires Dcp1 in fission yeast: its characterization in different species from yeast to human.
Deciphering Determinants in Ribosomal Methyltransferases That Confer Antimicrobial Resistance
Decoding the Mechanism of Specific RNA Targeting by Ribosomal Methyltransferases.
Deduced RNA binding mechanism of ThiI based on structural and binding analyses of a minimal RNA ligand.
Deep Knot Structure for Construction of Active Site and Cofactor Binding Site of tRNA Modification Enzyme
Deep knot structure for construction of active site and cofactor binding site of tRNA modification enzyme.
Defects in t 6 A tRNA modification due to GON7 and YRDC mutations lead to Galloway-Mowat syndrome.
Defects in tRNA Anticodon Loop 2'-O-Methylation Are Implicated in Nonsyndromic X-Linked Intellectual Disability due to Mutations in FTSJ1.
Deficient methylation and formylation of mt-tRNA(Met) wobble cytosine in a patient carrying mutations in NSUN3.
Deficit of tRNA(Lys) modification by Cdkal1 causes the development of type 2 diabetes in mice.
Deletion of gene encoding methyltransferase (gidB) confers high-level antimicrobial resistance in Salmonella.
Deletion of the Escherichia coli pseudouridine synthase gene truB blocks formation of pseudouridine 55 in tRNA in vivo, does not affect exponential growth, but confers a strong selective disadvantage in competition with wild-type cells.
Deletion of the MTO2 gene related to tRNA modification causes a failure in mitochondrial RNA metabolism in the yeast Saccharomyces cerevisiae.
Determinants of the CmoB carboxymethyl transferase utilized for selective tRNA wobble modification.
Determinants of the CmoB carboxymethyl transferase utilized for selective tRNA wobble modification.
Determinants of the CmoB carboxymethyl transferase utilized for selective tRNA wobble modification.
Determinants of tRNA editing and modification: Avoiding conundrums, affecting function.
Determination of DNA and RNA Methylation in Circulating Tumor Cells by Mass Spectrometry.
Determination of queuosine derivatives by reverse-phase liquid chromatography for the hypomodification study of Q-bearing tRNAs from various mammal liver cells.
Determination of the target nucleosides for members of two families of 16S rRNA methyltransferases that confer resistance to partially overlapping groups of aminoglycoside antibiotics.
Development of metachronous rectal cancers in a young man with dyskeratosis congenita: a case report.
Different mechanisms for pseudouridine formation in yeast 5S and 5.8S rRNAs.
Differential roles of archaeal box H/ACA proteins in guide RNA-dependent and independent pseudouridine formation.
Differential roles of human PUS10 in miRNA processing and tRNA pseudouridylation.
Differentiating analogous tRNA methyltransferases by fragments of the methyl donor.
Dim1p is required for efficient splicing and export of mRNA encoding lid1p, a component of the fission yeast anaphase-promoting complex.
Dim2p, a KH-domain protein required for small ribosomal subunit synthesis.
Dimerisation-dependent GTPase reaction of MnmE: how potassium acts as GTPase-activating element.
Dimerisation-dependent GTPase reaction of MnmE: how potassium acts as GTPase-activating element.
Dimerization of elongator protein 1 is essential for Elongator complex assembly.
Direct evidence for enzyme persulfide and disulfide intermediates during 4-thiouridine biosynthesis.
Direct evidence that ThiI is an ATP pyrophosphatase for the adenylation of uridine in 4-thiouridine biosynthesis.
Discovery and biological characterization of geranylated RNA in bacteria.
Discovery and characterization of an amidinotransferase involved in the modification of archaeal tRNA.
Discovery and characterization of tRNAIle lysidine synthetase (TilS).
Discovery of a gene family critical to wyosine base formation in a subset of phenylalanine-specific transfer RNAs.
Discovery of epoxyqueuosine (oQ) reductase reveals parallels between halorespiration and tRNA modification.
Discovery of the beta-barrel-type RNA methyltransferase responsible for N6-methylation of N6-threonylcarbamoyladenosine in tRNAs.
Disruption and functional analysis of six ORFs of chromosome IV: YDL103c (QRI1), YDL105w (QRI2), YDL112w (TRM3), YDL113c, YDL116w (NUP84) and YDL167c (NRP1).
Dissecting the roles of a strictly conserved tyrosine in substrate recognition and catalysis by pseudouridine 55 synthase
Distinct iron-sulfur cluster assembly complexes exist in the cytosol and mitochondria of human cells.
Distinct substrate specificities of the human tRNA methyltransferases TRMT10A and TRMT10B.
Distinct tRNA modifications in the thermo-acidophilic archaeon, Thermoplasma acidophilum.
Division of labour: tRNA methylation by the NSun2 tRNA methyltransferases Trm4a and Trm4b in fission yeast.
Dodecamer Structure of Severe Acute Respiratory Syndrome Coronavirus Nonstructural Protein nsp10
Doing it in reverse: 3'-to-5' polymerization by the Thg1 superfamily.
Domain Organization and Crystal Structure of the Catalytic Domain of E.coli RluF, a Pseudouridine Synthase that Acts on 23S rRNA
Domain organization and crystal structure of the catalytic domain of E.coli RluF, a pseudouridine synthase that acts on 23S rRNA.
Domain V of 23S rRNA contains all the structural elements necessary for recognition by the ErmE methyltransferase.
Down-Regulation of m6A mRNA Methylation Is Involved in Dopaminergic Neuronal Death.
Downregulation of N-methyladenosine binding YTHDF2 protein mediated by miR-493-3p suppresses prostate cancer by elevating N-methyladenosine levels.
DrosophilaYBX1 homolog YPS promotes ovarian germ line stem cell development by preferentially recognizing 5-methylcytosine RNAs.
Dual conformational recognition by Z-DNA binding protein is important for the B-Z transition process.
Dynamic association of capping enzymes with transcribing RNA polymerase II.
Dynamic inosinome profiles reveal novel patient stratification and gender-specific differences in glioblastoma.
Dynamic mA mRNA methylation reveals the role of METTL3-mA-CDCP1 signaling axis in chemical carcinogenesis.
Dynamic modulation of Dnmt2-dependent tRNA methylation by the micronutrient queuine.
Dynamics of RNA modification by a multi-site-specific tRNA methyltransferase.
Dysregulated N6-methyladenosine methylation writer METTL3 contributes to the proliferation and migration of gastric cancer.
Dysregulated N6-methyladenosine methylation writer METTL3 contributes to the proliferation and migration of gastric cancer.
Early-onset epilepsy and postnatal lethality associated with an editing-deficientGluR-B allele in mice.
Editing modifies the GABAA receptor subunit α3
Effect of a mutation in the anticodon of human mitochondrial tRNAPro on its post-transcriptional modification pattern.
Effects of mutagenesis in the switch I region and conserved arginines of Escherichia coli MnmE protein, a GTPase involved in tRNA modification.
Effects on transcription of mutations in ygjD, yeaZ, and yjeE genes, which are involved in a universal tRNA modification in Escherichia coli.
Ein neuer Zugang zu 2’-O-Alkylribonucleosiden und Eigenschaften deren Oligonucleotide
Electrostatic Potential in the tRNA Binding Evolution of Dihydrouridine Synthases.
Electrostatic Potential in the tRNA Binding Evolution of Dihydrouridine Synthases.
Elongator complex influences telomeric gene silencing and DNA damage response by its role in wobble uridine tRNA modification.
Elongator, a multisubunit component of a novel RNA polymerase II holoenzyme for transcriptional elongation.
Emerging themes in radical SAM chemistry.
Enzymatic characterization of three human RNA adenosine methyltransferases reveals diverse substrate affinities and reaction optima
Enzymatic formation of queuosine and of glycosyl queuosine in yeast tRNAs microinjected into Xenopus laevis oocytes. The effect of the anticodon loop sequence.
Enzymatic modification of tRNAs: MiaB is an iron-sulfur protein.
Enzymatic synthesis of Q nucleoside containing mannose in the anticodon of tRNA: isolation of a novel mannosyltransferase from a cell-free extract of rat liver.
Enzymology of tRNA modification in the bacterial MnmEG pathway.
Epigenetic control of rDNA loci in response to intracellular energy status
Epigenetic loss of m1A RNA demethylase ALKBH3 in Hodgkin lymphoma targets collagen, conferring poor clinical outcome.
Epigenetic loss of RNA-methyltransferase NSUN5 in glioma targets ribosomes to drive a stress adaptive translational program
ErmE methyltransferase recognizes features of the primary and secondary structure in a motif within domain V of 23 S rRNA.
Escherichia coli dimethylallyl diphosphate:tRNA dimethylallyltransferase: a binding mechanism for recombinant enzyme.
Escherichia coli dimethylallyl diphosphate:tRNA dimethylallyltransferase: essential elements for recognition of tRNA substrates within the anticodon stem-loop.
Escherichia coli mutant SELD enzymes. The cysteine 17 residue is essential for selenophosphate formation from ATP and selenide.
Escherichia coli QueD is a 6-carboxy-5,6,7,8-tetrahydropterin synthase.
Essential role of METTL3-mediated mA modification in glioma stem-like cells maintenance and radioresistance.
Essential role of METTL3-mediated mA modification in glioma stem-like cells maintenance and radioresistance.
Eukaryotic stand-alone pseudouridine synthases – RNA modifying enzymes and emerging regulators of gene expression?
Eukaryotic wobble uridine modifications promote a functionally redundant decoding system.
Evidence for an early gene duplication event in the evolution of the mitochondrial transcription factor B family and maintenance of rRNA methyltransferase activity in human mtTFB1 and mtTFB2.
Evidence for natural gene transfer from gram-positive cocci to Escherichia coli.
Evidence for the transfer of sulfane sulfur from IscS to ThiI during the in vitro biosynthesis of 4-thiouridine in Escherichia coli tRNA.
Evidence that the folate-dependent proteins YgfZ and MnmEG have opposing effects on growth and on activity of the iron-sulfur enzyme MiaB.
Evidence that ThiI, an enzyme shared between thiamin and 4-thiouridine biosynthesis, may be a sulfurtransferase that proceeds through a persulfide intermediate.
Evolutionarily conserved proteins MnmE and GidA catalyze the formation of two methyluridine derivatives at tRNA wobble positions.
Evolutionary conservation of the human nucleolar protein fibrillarin and its functional expression in yeast.
Expanded tRNA methyltransferase family member TRMT9B regulates synaptic growth and function
Expanding role of the jumonji C domain as an RNA hydroxylase.
Expanding the Kinome World: A New Protein Kinase Family Widely Conserved in Bacteria
Expression and analysis of the SAM-dependent RNA methyltransferase Rsm22 from Saccharomyces cerevisiae.
Expression and purification of untagged and histidine-tagged folate-dependent tRNA:m5U54 methyltransferase from Bacillus subtilis.
Expression and roles of Wilms' tumor 1-associating protein in glioblastoma.
Expression and roles of Wilms' tumor 1-associating protein in glioblastoma.
Expression of Demethylase Genes, FTO and ALKBH1, Is Associated with Prognosis of Gastric Cancer.
Expression of Demethylase Genes, FTO and ALKBH1, Is Associated with Prognosis of Gastric Cancer.
Expression of the mRNA (N6-adenosine)-methyltransferase S-adenosyl-L-methionine binding subunit mRNA in cultured cells.
Expression profiles and prognostic significance of RNA N6-methyladenosine-related genes in patients with hepatocellular carcinoma: evidence from independent datasets
Expression profiles and prognostic significance of RNA N6-methyladenosine-related genes in patients with hepatocellular carcinoma: evidence from independent datasets.
Expression, purification and preliminary X-ray analysis of a fibrillarin homolog from Methanococcus jannaschii, a hyperthermophile.
Extensive 5'-surveillance guards against non-canonical NAD-caps of nuclear mRNAs in yeast.
FAD/Folate-Dependent tRNA Methyltransferase: Flavin as a new methyl-transfer agent.
Family background of children with Down's syndrome and of children with a similar degree of mental retardation.
Fat mass and obesity-associated (FTO) protein regulates adult neurogenesis.
Fat mass-and obesity-associated (FTO) gene variant is associated with obesity: longitudinal analyses in two cohort studies and functional test.
FICC-Seq: a method for enzyme-specified profiling of methyl-5-uridine in cellular RNA.
Fine-tuning of the ribosomal decoding center by conserved methyl-modifications in the Escherichia coli 16S rRNA.
FIONA1 is an RNA N6-methyladenosine methyltransferase affecting Arabidopsis photomorphogenesis and flowering
FIONA1-Mediated m6 A Modification Regulates the Floral Transition in Arabidopsis
First-In-Class Small Molecule Inhibitors of the Single-Strand DNA Cytosine Deaminase APOBEC3G.
First-In-Class Small Molecule Inhibitors of the Single-Strand DNA Cytosine Deaminase APOBEC3G.
Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein
Fluorescent properties of an unnatural nucleobase, 2-amino-6-(2-thienyl)purine, in DNA and RNA fragments.
Formation of m2G6 in Methanocaldococcus jannaschii tRNA catalyzed by the novel methyltransferase Trm14.
Formation of the conserved pseudouridine at position 55 in archaeal tRNA.
Formation of thiolated nucleosides present in tRNA from Salmonella enterica serovar Typhimurium occurs in two principally distinct pathways.
FoxM1 Drives a Feed-Forward STAT3-Activation Signaling Loop That Promotes the Self-Renewal and Tumorigenicity of Glioblastoma Stem-like Cells.
Fragment Ligands of the m 6 A-RNA Reader YTHDF2.
From bacterial to human dihydrouridine synthase: automated structure determination.
From cyclohydrolase to oxidoreductase: discovery of nitrile reductase activity in a common fold.
FTO expression is associated with the occurrence of gastric cancer and prognosis.
FTO expression is associated with the occurrence of gastric cancer and prognosis.
FTO haplotyping underlines high obesity risk for European populations.
FTO is involved in Alzheimer's disease by targeting TSC1-mTOR-Tau signaling.
FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N(6)-Methyladenosine RNADemethylase.
FTO regulates the chemo-radiotherapy resistance of cervical squamous cell carcinoma (CSCC) by targeting β-catenin through mRNA demethylation.
FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis.
FTO-mediated formation of N(6)-hydroxymethyladenosine and N(6)-formyladenosine in mammalian RNA.
Function and detection of 5-methylcytosine in eukaryotic RNA.
Functional analysis of mRNA scavenger decapping enzymes.
Functional and Structural Impact of Target Uridine Substitutions on the H/ACA Ribonucleoprotein Particle Pseudouridine Synthase
Functional categorization of the conserved basic amino acid residues in TrmH (tRNA (Gm18) methyltransferase) enzymes.
Functional characterization of the eukaryotic cysteine desulfurase Nfs1p from Saccharomyces cerevisiae.
Functional characterization of the mammalian mRNA decapping enzyme hDcp2.
Functional characterization of the YmcB and YqeV tRNA methylthiotransferases of Bacillus subtilis.
Functional diversity of the rhodanese homology domain: the Escherichia coli ybbB gene encodes a selenophosphate-dependent tRNA 2-selenouridine synthase.
Functional effect of deletion and mutation of the Escherichia coli ribosomal RNA and tRNA pseudouridine synthase RluA.
Functional homology between yeast piD261/Bud32 and human PRPK: both phosphorylate p53 and PRPK partially complements piD261/Bud32 deficiency.
Functional Implications for a Prototypical K-Turn Binding Protein from Structural and Dynamical Studies of 15.5K
Functional interaction of a novel 15.5kD [U4/U6.U5] tri-snRNP protein with the 5' stem-loop of U4 snRNA.
Functional link between the mammalian exosome and mRNA decapping.
Functional organization of box C/D RNA-guided RNA methyltransferase.
Functional promiscuity of the COG0720 family.
Functional redundancy of Spb1p and a snR52-dependent mechanism for the 2'-O-ribose methylation of a conserved rRNA position in yeast.
Functional requirement of a site-specific ribose methylation in ribosomal RNA.
Functional specialization of domains tandemly duplicated within 16S rRNA methyltransferase RsmC
Functional specialization of domains tandemly duplicated within 16S rRNA methyltransferase RsmC.
Functionally critical residues in the aminoglycoside resistance-associated methyltransferase RmtC play distinct roles in 30S substrate recognition.
Functionally critical residues in the aminoglycoside resistance-associated methyltransferase RmtC play distinct roles in 30S substrate recognition.
Functions and consequences of AID/APOBEC-mediated DNA and RNA deamination
Functions and Regulation of RNA Editing by ADAR Deaminases
Further insights into the tRNA modification process controlled by proteins MnmE and GidA of Escherichia coli.
GAR1 is an essential small nucleolar RNP protein required for pre-rRNA processing in yeast.
GCD14p, a repressor of GCN4 translation, cooperates with Gcd10p and Lhp1p in the maturation of initiator methionyl-tRNA in Saccharomyces cerevisiae.
Gcn4 misregulation reveals a direct role for the evolutionary conserved EKC/KEOPS in the t6A modification of tRNAs.
Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis.
Genetic alterations of mA regulators predict poorer survival in acute myeloid leukemia.
Genetic analysis identifies a function for the queC (ybaX) gene product at an initial step in the queuosine biosynthetic pathway in Escherichia coli.
Genetic and biochemical analysis of yeast and human cap trimethylguanosine synthase: functional overlap of 2,2,7-trimethylguanosine caps, small nuclear ribonucleoprotein components, pre-mRNA splicing factors, and RNA decay pathways.
Genetic associations and regulation of expression indicate an independent role for14q32 snoRNAs in human cardiovascular disease.
Genetic dissection of synthesis and function of modified nucleosides in bacterial transfer RNA.
Genetic interactions show the importance of rRNA modification machinery for the role of Rps15p during ribosome biogenesis in S. cerevisiae.
Genetic mapping and cloning of the gene (trmC) responsible for the synthesis of tRNA (mnm5s2U)methyltransferase in Escherichia coli K12.
Genetic variants in the Fat and Obesity Associated (FTO) gene and risk ofAlzheimer's disease.
Genome-wide association scan shows genetic variants in the FTO gene are associatedwith obesity-related traits.
Germline copy number variation in the YTHDC2 gene: does it have a role in finding a novel potential molecular target involved in pancreatic adenocarcinoma susceptibility?
Germline NPM1 mutations lead to altered rRNA 2'-O-methylation and cause dyskeratosis congenita.
Giardia lamblia RNA cap guanine-N2 methyltransferase (Tgs2).
Global analysis of A-to-I RNA editing reveals association with common disease variants.
Glu-Q-tRNA(Asp) synthetase coded by the yadB gene, a new paralog of aminoacyl-tRNA synthetase that glutamylates tRNA(Asp) anticodon.
Glycosidic bond conformation preference plays a pivotal role in catalysis of RNA pseudouridylation: a combined simulation and structural study.
Harnessing human ADAR2 for RNA repair - Recoding a PINK1 mutation rescues mitophagy.
HBXIP-elevated methyltransferase METTL3 promotes the progression of breast cancervia inhibiting tumor suppressor let-7g.
Helicase of Type 2 Porcine Reproductive and Respiratory Syndrome Virus Strain HV Reveals a Unique Structure.
HEN1 recognizes 21-24 nt small RNA duplexes and deposits a methyl group onto the 2' OH of the 3' terminal nucleotide.
High precision NMR structure of YhhP, a novel Escherichia coli protein implicated in cell division.
High precision NMR structure of YhhP, a novel Escherichia coli protein implicated in cell division.
High tRNA Transferase NSUN2 Gene Expression is Associated with Poor Prognosis inHead and Neck Squamous Carcinoma.
High-resolution structure of eukaryotic Fibrillarin interacting with Nop56 amino-terminal domain.
High-resolution structures of the SARS-CoV-2 2'- O -methyltransferase reveal strategies for structure-based inhibitor design.
High-resolution structures of the SARS-CoV-2 2'- O -methyltransferase reveal strategies for structure-based inhibitor design.
High-resolution structures of the SARS-CoV-2 2'--methyltransferase reveal strategies for structure-based inhibitor design.
hLARP7 C-terminal domain contains an xRRM that binds the 3' hairpin of 7SK RNA.
HNRNPA2/B1 is upregulated in endocrine-resistant LCC9 breast cancer cells and alters the miRNA transcriptome when overexpressed in MCF-7 cells.
How U38, 39, and 40 of many tRNAs become the targets for pseudouridylation by TruA.
How U38, 39, and 40 of Many tRNAs Become the Targets for Pseudouridylation by TruA.
How U38, 39, and 40 of Many tRNAs Become the Targets for Pseudouridylation by TruA.
Human Abh3 Structure and Key Residues for Oxidative Demethylation to Reverse DNA/RNA Damage.
Human AlkB homolog ABH8 Is a tRNA methyltransferase required for wobble uridine modification and DNA damage survival.
Human AlkB homologue 5 is a nuclear 2-oxoglutarate dependent oxygenase and a direct target of hypoxia-inducible factor 1alpha (HIF-1alpha).
Human ALKBH3-induced m(1)A demethylation increases the CSF-1 mRNA stability inbreast and ovarian cancer cells.
Human BLCAP transcript: new editing events in normal andcancerous tissues
Human cells have a limited set of tRNA anticodon loop substrates of the tRNA isopentenyltransferase TRIT1 tumor suppressor
Human Dcp2: a catalytically active mRNA decapping enzyme located in specific cytoplasmic structures.
Human fibrillarin forms a sub-complex with splicing factor 2-associated p32, protein arginine methyltransferases, and tubulins alpha 3 and beta 1 that is independent of its association with preribosomal ribonucleoprotein complexes.
Human mitochondrial diseases caused by lack of taurine modification in mitochondrial tRNAs.
Human mitochondrial transcription factor B1 methylates ribosomal RNA at a conserved stem-loop.
Human mitochondrial tRNAs: biogenesis, function, structural aspects, and diseases.
Human mRNA cap methyltransferase: alternative nuclear localization signal motifs ensure nuclear localization required for viability.
Human NAT10 is an ATP-dependent RNA acetyltransferase responsible for N4-acetylcytidine formation in 18S rRNA.
Human RNA Methyltransferase BCDIN3D Regulates MicroRNA Processing.
Human TRMT1 catalyzes m2G or m22G formation on tRNAs in a substrate-dependent manner
Human TRMU encoding the mitochondrial 5-methylaminomethyl-2-thiouridylate-methyltransferase is a putative nuclear modifier gene for the phenotypic expression of the deafness-associated 12S rRNA mutations.
Hydroxylation of a conserved tRNA modification establishes non-universal genetic code in echinoderm mitochondria.
Hypermethylated-capped selenoprotein mRNAs in mammals.
Hypermethylation of 28S ribosomal RNA in β-thalassemia trait carriers.
Hypermethylation of the cap structure of both yeast snRNAs and snoRNAs requires a conserved methyltransferase that is localized to the nucleolus.
Hypermethylation of yeast telomerase RNA by the snRNA and snoRNA methyltransferase Tgs1.
Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m⁶A-demethylation of NANOG mRNA.
Identification and characterization of a human tRNA-specific adenosine deaminase related to the ADAR family of pre-mRNA editing enzymes.
Identification and characterization of RsmE, the founding member of a new RNA base methyltransferase family.
Identification and characterization of the Thermus thermophilus 5-methylcytidine (m5C) methyltransferase modifying 23 S ribosomal RNA (rRNA) base C1942.
Identification and Characterization of the Thermus thermophilus 5-Methylcytidine (m5C) Methyltransferase Modifying 23 S Ribosomal RNA (rRNA) Base C1942.
Identification and characterization of the tRNA:Psi 31-synthase (Pus6p) of Saccharomyces cerevisiae.
Identification and characterization of tRNA (Gm18) methyltransferase from Thermus thermophilus HB8: domain structure and conserved amino acid sequence motifs.
Identification and codon reading properties of 5-cyanomethyl uridine, a new modified nucleoside found in the anticodon wobble position of mutant haloarchaeal isoleucine tRNAs.
Identification and site of action of the remaining four putative pseudouridine synthases in Escherichia coli.
Identification of 2-methylthio cyclic N6-threonylcarbamoyladenosine (ms2ct6A) as a novel RNA modification at position 37 of tRNAs
Identification of 5-hydroxycytidine at position 2501 concludes characterization of modified nucleotides in E. coli 23S rRNA.
Identification of 8-methyladenosine as the modification catalyzed by the radical SAM methyltransferase Cfr that confers antibiotic resistance in bacteria.
Identification of a bifunctional enzyme MnmC involved in the biosynthesis of a hypermodified uridine in the wobble position of tRNA.
Identification of a gene involved in the generation of 4-thiouridine in tRNA.
Identification of a novel 5-aminomethyl-2-thiouridine methyltransferase in tRNA modification.
Identification of a novel gene encoding a flavin-dependent tRNA:m5U methyltransferase in bacteria--evolutionary implications.
Identification of a novel methyltransferase, Bmt2, responsible for the N-1-methyl-adenosine base modification of 25S rRNA in Saccharomyces cerevisiae
Identification of a novel tRNA wobble uridine modifying activity in the biosynthesis of 5-methoxyuridine.
Identification of a novel tRNA wobble uridine modifying activity in the biosynthesis of 5-methoxyuridine.
Identification of a quality-control mechanism for mRNA 5'-end capping.
Identification of a tRNA isopentenyltransferase gene from Arabidopsis thaliana.
Identification of Aquifex aeolicus tRNA (m2(2G26) methyltransferase gene.
Identification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cells.
Identification of CGI-121, a novel PRPK (p53-related protein kinase)-binding protein.
Identification of determinants for tRNA substrate recognition by Escherichia coli C/U34 2'-O-methyltransferase.
Identification of determinants in the protein partners aCBF5 and aNOP10 necessary for the tRNA:Psi55-synthase and RNA-guided RNA:Psi-synthase activities.
Identification of entacapone as a chemical inhibitor of FTO mediating metabolic regulation through FOXO1
Identification of Escherichia coli m2G methyltransferases: I. the ycbY gene encodes a methyltransferase specific for G2445 of the 23 S rRNA.
Identification of Escherichia coli m2G methyltransferases: II. The ygjO gene encodes a methyltransferase specific for G1835 of the 23 S rRNA.
Identification of eukaryotic and prokaryotic methylthiotransferase for biosynthesis of 2-methylthio-N6-threonylcarbamoyladenosine in tRNA.
Identification of factors required for m(6) A mRNA methylation in Arabidopsis reveals a role for the conserved E3 ubiquitin ligase HAKAI.
Identification of factors required for m6 A mRNA methylation in Arabidopsis reveals a role for the conserved E3 ubiquitin ligase HAKAI
Identification of factors required for m6 A mRNA methylation in Arabidopsis reveals a role for the conserved E3 ubiquitin ligase HAKAI
Identification of four genes necessary for biosynthesis of the modified nucleoside queuosine.
Identification of human tRNA:m5C methyltransferase catalysing intron-dependent m5C formation in the first position of the anticodon of the pre-tRNA Leu (CAA).
Identification of novel methyltransferases, Bmt5 and Bmt6, responsible for the m3U methylations of 25S rRNA in Saccharomyces cerevisiae.
Identification of pseudouridine methyltransferase in Escherichia coli.
Identification of the 16S rRNA m5C967 methyltransferase from Escherichia coli.
Identification of the chloroplast adenosine-to-inosine tRNA editing enzyme.
Identification of the enzyme responsible for N1-methylation of pseudouridine 54 in archaeal tRNAs.
Identification of the mAm Methyltransferase PCIF1 Reveals the Location and Functions of mAm in the Transcriptome.
Identification of the methyltransferase targeting C2499 in Deinococcus radiodurans 23S ribosomal RNA.
Identification of the miaB gene, involved in methylthiolation of isopentenylated A37 derivatives in the tRNA of Salmonella typhimurium and Escherichia coli.
Identification of the rrmA gene encoding the 23S rRNA m1G745 methyltransferase in Escherichia coli and characterization of an m1G745-deficient mutant.
Identification of the RsmG methyltransferase target as 16S rRNA nucleotide G527 and characterization of Bacillus subtilis rsmG mutants.
Identification of the Saccharomyces cerevisiae RNA:pseudouridine synthase responsible for formation of psi(2819) in 21S mitochondrial ribosomal RNA.
Identification of the TRM2 gene encoding the tRNA(m5U54)methyltransferase of Saccharomyces cerevisiae.
Identification of the tRNA-dihydrouridine synthase family.
Identification of the yeast gene encoding the tRNA m1G methyltransferase responsible for modification at position 9.
Identification of two Escherichia coli pseudouridine synthases that show multisite specificity for 23S RNA.
Identification of two tRNA thiolation genes required for cell growth at extremely high temperatures.
Identification of yeast tRNA Um(44) 2'-O-methyltransferase (Trm44) and demonstration of a Trm44 role in sustaining levels of specific tRNA(Ser) species.
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase.
Identifying the methyltransferases for m(5)U747 and m(5)U1939 in 23S rRNA using MALDI mass spectrometry.
Implications of a functional large ribosomal RNA with only three modified nucleotides.
In Human Pseudouridine Synthase 1 (hPus1), a C-Terminal Helical Insert Blocks tRNA from Binding in the Same Orientation as in the Pus1 Bacterial Homologue TruA, Consistent with Their Different Target Selectivities.
In Human Pseudouridine Synthase 1 (hPus1), a C-Terminal Helical Insert Blocks tRNA from Binding in the Same Orientation as in the Pus1 Bacterial Homologue TruA, Consistent with Their Different Target Selectivities.
In silico analysis of the tRNA:m1A58 methyltransferase family: homology-based fold prediction and identification of new members from Eubacteria and Archaea.
In vitro synthesis of selenocysteinyl-tRNA(UCA) from seryl-tRNA(UCA): involvement and characterization of the selD gene product.
Inactivation of KsgA, a 16S rRNA methyltransferase, causes vigorous emergence of mutants with high-level kasugamycin resistance.
Inactivation of the Fto gene protects from obesity.
Increased adenosine-to-inosine RNA editing in rheumatoid arthritis
Increased N6-methyladenosine causes infertility is associated with FTO expression.
Induction of sporulation in Saccharomyces cerevisiae leads to the formation of N6-methyladenosine in mRNA: a potential mechanism for the activity of the IME4 gene.
Influence of phylogeny on posttranscriptional modification of rRNA in thermophilic prokaryotes: the complete modification map of 16S rRNA of Thermus thermophilus.
Influence of temperature on tRNA modification in archaea: Methanococcoides burtonii (optimum growth temperature [Topt], 23 degrees C) and Stetteria hydrogenophila (Topt, 95 degrees C).
Initiator tRNAs from archaebacteria show common unique sequence characteristics.
Inositol hexakisphosphate is bound in the ADAR2 core and required for RNA editing.
Insights into catalysis by a knotted TrmD tRNA methyltransferase.
Insights into Catalysis by a Knotted TrmD tRNA Methyltransferase.
Insights into DNA substrate selection by APOBEC3G from structural, biochemical, and functional studies.
Insights into folate/FAD-dependent tRNA methyltransferase mechanism: role of two highly conserved cysteines in catalysis.
Insights into molecular plasticity in protein complexes from Trm9-Trm112 tRNA modifying enzyme crystal structure.
Insights into molecular plasticity in protein complexes from Trm9-Trm112 tRNA modifying enzyme crystal structure.
Insights into the hyperthermostability and unusual region-specificity of archaeal Pyrococcus abyssi tRNA m1A57/58 methyltransferase.
Insights into the hyperthermostability and unusual region-specificity of archaeal Pyrococcus abyssi tRNA m1A57/58 methyltransferase.
Insights into the hyperthermostability and unusual region-specificity of archaeal Pyrococcus abyssi tRNA m1A57/58 methyltransferase.
Insights into the structure, function and evolution of the radical-SAM 23S rRNA methyltransferase Cfr that confers antibiotic resistance in bacteria.
Insights into the structure, mechanism, and regulation of scavenger mRNA decapping activity
Insights into the structure, mechanism, and regulation of scavenger mRNA decapping activity
Insights into the structure, mechanism, and regulation of scavenger mRNA decapping activity.
Interaction mode between catalytic and regulatory subunits in glucosidase II involved in ER glycoprotein quality control
Interaction of the tylosin-resistance methyltransferase RlmA II at its rRNA target differs from the orthologue RlmA I.
Intrinsic resistance to aminoglycosides in Enterococcus faecium is conferred by the 16S rRNA m5C1404-specific methyltransferase EfmM.
Introduction of hypermodified nucleotides in RNA.
Intron-dependent formation of pseudouridines in the anticodon of Saccharomyces cerevisiae minor tRNA(Ile).
Iron-sulfur cluster assembly: characterization of IscA and evidence for a specific and functional complex with ferredoxin.
Iron-sulfur cluster biosynthesis in bacteria: Mechanisms of cluster assembly and transfer.
IscS is a sulfurtransferase for the in vitro biosynthesis of 4-thiouridine in Escherichia coli tRNA.
Isd11p protein activates the mitochondrial cysteine desulfurase Nfs1p protein.
Isolation and characterization of a human cDNA for mRNA 5'-capping enzyme.
Isolation and characterization of MOD5, a gene required for isopentenylation of cytoplasmic and mitochondrial tRNAs of Saccharomyces cerevisiae.
Isolation and characterization of SUA5, a novel gene required for normal growth in Saccharomyces cerevisiae.
Isolation and characterization of the human tRNA-(N1G37) methyltransferase (TRM5) and comparison to the Escherichia coli TrmD protein.
Isolation and characterization of the TRM1 locus, a gene essential for the N2,N2-dimethylguanosine modification of both mitochondrial and cytoplasmic tRNA in Saccharomyces cerevisiae.
Isolation and characterization of the yeast mRNA capping enzyme beta subunit gene encoding RNA 5'-triphosphatase, which is essential for cell viability.
Isolation and sequencing of NOP1. A yeast gene encoding a nucleolar protein homologous to a human autoimmune antigen.
Isolation of 5-hydroxyuridine (iso-barbituridine) from yeast ribonucleic acids.
Isolation of temperature-sensitive mutants for mRNA capping enzyme in Saccharomyces cerevisiae.
Isolation of the gene (miaE) encoding the hydroxylase involved in the synthesis of 2-methylthio-cis-ribozeatin in tRNA of Salmonella typhimurium and characterization of mutants.
KIAA1429 contributes to liver cancer progression through N6-methyladenosine-dependent post-transcriptional modification of GATA3.
KIAA1429 regulates the migration and invasion of hepatocellular carcinoma by altering m6A modification of ID2 mRNA.
Kinetic and functional analysis of the small RNA methyltransferase HEN1: the catalytic domain is essential for preferential modification of duplex RNA.
Kissing G domains of MnmE monitored by X-ray crystallography and pulse electron paramagnetic resonance spectroscopy
Kissing G domains of MnmE monitored by X-ray crystallography and pulse electron paramagnetic resonance spectroscopy.
KMT9 monomethylates histone H4 lysine 12 and controls proliferation of prostate cancer cells.
Known bioactive small molecules probe the function of a widely conserved but enigmatic bacterial ATPase, YjeE.
Lack of pseudouridine 38/39 in the anticodon arm of yeast cytoplasmic tRNA decreases in vivo recoding efficiency.
LC/MS analysis and deep sequencing reveal the accurate RNA composition in the HIV-1 virion.
LC/MS analysis of cellular RNA reveals NAD-linked RNA.
Letter: The structure of Q* nucleoside isolated from rabbit liver transfer ribonucleic acid.
Life without the essential bacterial tRNA Ile2-lysidine synthetase TilS: a case of tRNA gene recruitment in Bacillus subtilis.
Ligand-mediated anticodon conformational changes occur during tRNA methylation by a TrmD methyltransferase.
Local cerebral glucose consumption during ethanol withdrawal in the rat: effects of single and multiple episodes and previous convulsive seizures.
Loss of 5-methylcytosine alters the biogenesis of vault-derived small RNAs to coordinate epidermal differentiation.
Loss of a conserved 7-methylguanosine modification in 16S rRNA confers low-level streptomycin resistance in bacteria.
Loss of a Conserved tRNA Anticodon Modification Perturbs Plant Immunity.
Loss of a universal tRNA feature.
Loss of Ftsj1 perturbs codon-specific translation efficiency in the brain and is associated with X-linked intellectual disability.
Loss of the ribosomal RNA methyltransferase NSUN5 impairs global protein synthesis and normal growth
m(6)A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells bySustaining FOXM1 Expression and Cell Proliferation Program.
m(6)A demethylase FTO facilitates tumor progression in lung squamous cell carcinomaby regulating MZF1 expression.
m(6)A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of GlioblastomaStem Cells.
m1A Regulated Genes Modulate PI3K/AKT/mTOR and ErbB Pathways in GastrointestinalCancer.
m6A modification of U6 snRNA modulates usage of two major classes of pre-mRNA 5' splice site
M6A-mediated upregulation of LINC00958 increases lipogenesis and acts as a nanotherapeutic target in hepatocellular carcinoma.
mA demethylase ALKBH5 inhibits pancreatic cancer tumorigenesis by decreasing WIF-1 RNA methylation and mediating Wnt signaling.
mA methyltransferase METTL3 suppresses colorectal cancer proliferation and migration through p38/ERK pathways.
mA modification suppresses ocular melanoma through modulating HINT2 mRNA translation.
mA mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade.
mA mRNA methylation initiated by METTL3 directly promotes YAP translation and increases YAP activity by regulating the MALAT1-miR-1914-3p-YAP axis to induce NSCLC drug resistance and metastasis.
mA mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer.
mA mRNA Methylation Regulates Human β-Cell Biology in Physiological States and in Type 2 Diabetes.
mA-induced lncRNA RP11 triggers the dissemination of colorectal cancer cells via upregulation of Zeb1.
Major Reorientation of tRNA Substrates Defines Specificity of Dihydrouridine Synthases.
Major reorientation of tRNA substrates defines specificity of dihydrouridine synthases.
Mammalian ALKBH8 possesses tRNA methyltransferase activity required for the biogenesis of multiple wobble uridine modifications implicated in translational decoding.
Mammalian nuclear TRUB1, mitochondrial TRUB2, and cytoplasmic PUS10 produce conserved pseudouridine 55 in different sets of tRNA.
Mammalian Nudix proteins cleave nucleotide metabolite caps on RNAs.
Mechanism and substrate specificity of tRNA-guanine transglycosylases (TGTs): tRNA-modifying enzymes from the three different kingdoms of life share a common catalytic mechanism.
Mechanism of 5' splice site transfer for human spliceosome activation.
Mechanism of dihydrouridine synthase 2 from yeast and the importance of modifications for efficient tRNA reduction.
Mechanism of mitoribosomal small subunit biogenesis and preinitiation.
Mechanism of N-methylation by the tRNA m1G37 methyltransferase Trm5.
Mechanism of N6-threonylcarbamoyladenonsine (t(6)A) biosynthesis: isolation and characterization of the intermediate threonylcarbamoyl-AMP.
Mechanisms of substrate recognition and N6-methyladenosine demethylation revealed by crystal structures of ALKBH5-RNA complexes.
Mechanistic characterization of the sulfur-relay system for eukaryotic 2-thiouridine biogenesis at tRNA wobble positions.
Mechanistic insight into the ribosome biogenesis functions of the ancient protein KsgA.
Mechanistic insights into m6A modification of U6 snRNA by human METTL16.
Mechanistic insights into small RNA recognition and modification by the HEN1 methyltransferase.
Mechanistic insights into sulfur relay by multiple sulfur mediators involved in thiouridine biosynthesis at tRNA wobble positions.
Mechanistic investigations of the pseudouridine synthase RluA using RNA containing 5-fluorouridine.
Mechanistic studies of Bacillus subtilis QueF, the nitrile oxidoreductase involved in queuosine biosynthesis.
Meclofenamic acid selectively inhibits FTO demethylation of m6A over ALKBH5.
Messenger RNA guanylyltransferase from Saccharomyces cerevisiae. Large scale purification, subunit functions, and subcellular localization.
Methylaminedeprotectionprovidesincreasedyield of oligoribonucleotides
Methylated 23S rRNA nucleotide m2G1835 of Escherichia coli ribosome facilitates subunit association.
Methylation as a crucial step in plant microRNA biogenesis.
Methylation by NSun2 represses the levels and function of microRNA 125b.
Methylation of 12S rRNA is necessary for in vivo stability of the small subunit of the mammalian mitochondrial ribosome.
Methylation of 23S rRNA nucleotide G745 is a secondary function of the RlmAI methyltransferase.
Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan.
Methylation of Structured RNA by the m6A Writer METTL16 Is Essential for Mouse Embryonic Development.
Methylation of Structured RNA by the m6A Writer METTL16 Is Essential for Mouse Embryonic Development.
Methylation of tRNAAsp by the DNA methyltransferase homolog Dnmt2.
Methylation protects miRNAs and siRNAs from a 3'-end uridylation activity in Arabidopsis.
Methyltransferase that modifies guanine 966 of the 16 S rRNA: functional identification and tertiary structure.
Methyltransferase that modifies guanine 966 of the 16 S rRNA: functional identification and tertiary structure.
Mettl14 inhibits bladder TIC self-renewal and bladder tumorigenesis through N-methyladenosine of Notch1.
METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and PromotesLeukemogenesis via mRNA m(6)A Modification.
METTL14 Suppresses CRC Progression via Regulating N6-Methyladenosine-DependentPrimary miR-375 Processing.
METTL14 suppresses the metastatic potential of hepatocellular carcinoma by modulating N -methyladenosine-dependent primary MicroRNA processing.
METTL15 interacts with the assembly intermediate of murine mitochondrial small ribosomal subunit to form m4C840 12S rRNA residue.
METTL15 introduces N4-methylcytidine into human mitochondrial 12S rRNA and is required for mitoribosome biogenesis.
METTL3 and ALKBH5 oppositely regulate mA modification of mRNA, which dictates the fate of hypoxia/reoxygenation-treated cardiomyocytes.
METTL3 facilitates tumor progression via an mA-IGF2BP2-dependent mechanism in colorectal carcinoma.
METTL3 Inhibitors for Epitranscriptomic Modulation of Cellular Processes.
METTL3 promote tumor proliferation of bladder cancer by accelerating pri-miR221/222 maturation in m6A-dependent manner.
METTL3 Promotes the Proliferation and Mobility of Gastric Cancer Cells
METTL3 Promotes the Proliferation and Mobility of Gastric Cancer Cells.
Mettl3-mediated mA RNA methylation regulates the fate of bone marrow mesenchymal stem cells and osteoporosis.
METTL4 is an snRNA mAm methyltransferase that regulates RNA splicing.
MiaB protein from Thermotoga maritima. Characterization of an extremely thermophilic tRNA-methylthiotransferase.
MiaB protein is a bifunctional radical-S-adenosylmethionine enzyme involved in thiolation and methylation of tRNA.
MiaB, a bifunctional radical-S-adenosylmethionine enzyme involved in the thiolation and methylation of tRNA, contains two essential [4Fe-4S] clusters.
MicroRNA-145 Modulates -Methyladenosine Levels by Targeting the 3'-Untranslated mRNA Region of the -Methyladenosine Binding YTH Domain Family 2 Protein.
MiR-33a suppresses proliferation of NSCLC cells via targeting METTL3 mRNA.
Missense mutation in pseudouridine synthase 1 (PUS1) causes mitochondrial myopathyand sideroblastic anemia (MLASA).
Mitochondria-specific RNA-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial tRNAs. Implications for the molecular pathogenesis of human mitochondrial diseases.
Mitochondrial 16S rRNA Is Methylated by tRNA Methyltransferase TRMT61B in All Vertebrates.
Mitochondrial myopathy and sideroblastic anemia (MLASA): missense mutation in the pseudouridine synthase 1 (PUS1) gene is associated with the loss of tRNA pseudouridylation.
Mitochondrial tRNA import in Toxoplasma gondii.
MnmA and IscS are required for in vitro 2-thiouridine biosynthesis in Escherichia coli.
Modifications Modulate Anticodon Loop Dynamics and Codon Recognition of E. coli tRNA(Arg1,2).
Modulation of microRNA editing, expression and processing by ADAR2 deaminase in glioblastoma.
Molecular architecture of the 90S small subunit pre-ribosome
Molecular architecture of the 90S small subunit pre-ribosome.
Molecular architecture of the human U4/U6.U5 tri-snRNP.
Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1
Molecular basis for transfer RNA recognition by the double-stranded RNA-binding domain of human dihydrouridine synthase 2.
Molecular basis of box C/D RNA-protein interactions; cocrystal structure of archaeal L7Ae and a box C/D RNA.
Molecular Basis of Box C/D RNA-Protein Interactions; Cocrystal Structure of Archaeal L7Ae and a Box C/D RNA.
Molecular basis of tRNA recognition by the Elongator complex.
Molecular biology. Internal mRNA methylation finally finds functions.
Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editing
Molecular cloning of the Escherichia coli miaA gene involved in the formation of delta 2-isopentenyl adenosine in tRNA.
Molecular determinants of dihydrouridine synthase activity.
Molecular evolution of dihydrouridine synthases.
Molecular Interactions of a DNA Modifying Enzyme APOBEC3F Catalytic Domain with a Single-Stranded DNA.
Molecular phylogenetics and comparative modeling of HEN1, a methyltransferase involved in plant microRNA biogenesis.
Molecular phylogenetics of the RrmJ/fibrillarin superfamily of ribose 2'-O-methyltransferases.
Molecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA.
Molecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA.
Molybdenum cofactor biosynthesis in humans: identification of a persulfide group in the rhodanese-like domain of MOCS3 by mass spectrometry.
Monomeric tRNA (m(7)G46) methyltransferase from Escherichia coli presents a novel structure at the function-essential insertion
Monomeric tRNA (m(7)G46) methyltransferase from Escherichia coli presents a novel structure at the function-essential insertion
Mouse Trmt2B protein is a dual specific mitochondrial metyltransferase responsible for mU formation in both tRNA and rRNA.
MRM2 and MRM3 are involved in biogenesis of the large subunit of the mitochondrial ribosome.
MRM2 encodes a novel yeast mitochondrial 21S rRNA methyltransferase.
mRNA capping enzyme. Isolation and characterization of the gene encoding mRNA guanylytransferase subunit from Saccharomyces cerevisiae.
mRNA circularization by METTL3-eIF3h enhances translation and promotes oncogenesis.
mRNA:guanine-N7 cap methyltransferases: identification of novel members of the family, evolutionary analysis, homology modeling, and analysis of sequence-structure-function relationships.
MSS1, a nuclear-encoded mitochondrial GTPase involved in the expression of COX1 subunit of cytochrome c oxidase.
MTA is an Arabidopsis messenger RNA adenosine methylase and interacts with a homolog of a sex-specific splicing factor.
MTERF4 regulates translation by targeting the methyltransferase NSUN4 to the mammalian mitochondrial ribosome.
MTO1 codes for a mitochondrial protein required for respiration in paromomycin-resistant mutants of Saccharomyces cerevisiae.
mU54 tRNA Hypomodification by Lack of TRMT2A Drives the Generation of tRNA-Derived Small RNAs.
Multi-site-specific 16S rRNA methyltransferase RsmF from Thermus thermophilus.
Multi-site-specific 16S rRNA methyltransferase RsmF from Thermus thermophilus.
Multi-site-specific 16S rRNA methyltransferase RsmF from Thermus thermophilus.
Multi-site-specific 16S rRNA methyltransferase RsmF from Thermus thermophilus.
Multiple enzymatic activities associated with severe acute respiratory syndrome coronavirus helicase.
Multiple mRNA decapping enzymes in mammalian cells.
Multisite-specific archaeosine tRNA-guanine transglycosylase (ArcTGT) from Thermoplasma acidophilum, a thermo-acidophilic archaeon.
Multisite-specific tRNA:m5C-methyltransferase (Trm4) in yeast Saccharomyces cerevisiae: identification of the gene and substrate specificity of the enzyme.
Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase reveal aspartate 102 as the active site nucleophile.
Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase to elucidate the role of serine 103 for enzymatic activity.
Mutagenesis of the modified bases, m(5)U1939 and psi2504, in Escherichia coli 23S rRNA.
Mutagenesis of the peptidyltransferase center of 23S rRNA: the invariant U2449 is dispensable.
Mutation in TRMU related to transfer RNA modification modulates the phenotypic expression of the deafness-associated mitochondrial 12S ribosomal RNA mutations.
Mutation in WDR4 impairs tRNA m(7)G46 methylation and causes a distinct form of microcephalic primordial dwarfism.
Mutational analysis of the Saccharomyces cerevisiae ABD1 gene: cap methyltransferase activity is essential for cell growth.
Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature.
Mutations in MTO2 related to tRNA modification impair mitochondrial gene expression and protein synthesis in the presence of a paromomycin resistance mutation in mitochondrial 15 S rRNA.
Mutations in rsmG, encoding a 16S rRNA methyltransferase, result in low-level streptomycin resistance and antibiotic overproduction in Streptomyces coelicolor A3(2).
Mutations in the FTSJ1 gene coding for a novel S-adenosylmethionine-binding protein cause nonsyndromic X-linked mental retardation.
Mutations of the RNA-Specific Adenosine Deaminase Gene (DSRAD) Are Involved in Dyschromatosis Symmetrica Hereditaria
Mutually exclusive substrate selection strategy by human m3C RNA transferases METTL2A and METTL6.
Mycobacterium tuberculosis Rv2118c codes for a single-component homotetrameric m1A58 tRNA methyltransferase.
N(6)-methyladenosine ALKBH5 promotes non-small cell lung cancer progress byregulating TIMP3 stability.
N-Deoxyadenosine Methylation in Mammalian Mitochondrial DNA.
N-methyladenosine contributes to cellular phenotype in a genetically-defined model of breast cancer progression.
N1-methyladenosine profiling of long non-coding RNA in colorectal cancer.
N2-methylation of guanosine at position 10 in tRNA is catalyzed by a THUMP domain-containing, S-adenosylmethionine-dependent methyltransferase, conserved in Archaea and Eukaryota.
N6-Acetyladenosine: a new modified nucleoside from Methanopyrus kandleri tRNA.
N6-adenosine methylation in mRNA: substrate specificity and enzyme complexity.
N6-methyladenosine demethylase FTO suppresses clear cell renal cell carcinoma through a novel FTO-PGC-1α signalling axis.
N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO.
N6-methyladenosine induced miR-143-3p promotes the brain metastasis of lung cancer via regulation of VASH1.
N6-methyladenosine METTL3 promotes the breast cancer progression via targetingBcl-2.
N6-methyladenosine-related Genomic Targets are Altered in Breast Cancer Tissue and Associated with Poor Survival.
New and convenient protection system for pseudouridine, highly suitable for solid-phase oligoribonucleotide synthesis
New bioinformatic tools for analysis of nucleotide modifications in eukaryotic rRNA.
New function of vitamin B12: cobamide-dependent reduction of epoxyqueuosine to queuosine in tRNAs of Escherichia coli and Salmonella typhimurium.
New structural insights reveal an expanded reaction cycle for inositol pyrophosphate hydrolysis by human DIPP1.
New structural insights reveal an expanded reaction cycle for inositol pyrophosphate hydrolysis by human DIPP1.
Nhp2p and Nop10p are essential for the function of H/ACA snoRNPs.
NMethyladenosine methyltransferase ZCCHC4 mediates ribosomal RNA methylation.
NMR structure of human restriction factor APOBEC3A reveals substrate binding and enzyme specificity.
NMR-based Structural Analysis of Threonylcarbamoyl-AMP Synthase and Its Substrate Interactions.
Nop2p is required for pre-rRNA processing and 60S ribosome subunit synthesis in yeast.
Nop5p is a small nucleolar ribonucleoprotein component required for pre-18 S rRNA processing in yeast.
Novel long noncoding RNA NMR promotes tumor progression via NSUN2 and BPTF inesophageal squamous cell carcinoma.
Novel methyltransferase for modified uridine residues at the wobble position of tRNA.
Novel plasmid-mediated 16S rRNA m1A1408 methyltransferase, NpmA, found in a clinically isolated Escherichia coli strain resistant to structurally diverse aminoglycosides.
NSUN2 modified by SUMO-2/3 promotes gastric cancer progression and regulates mRNA m5C methylation.
NSUN3 and ABH1 modify the wobble position of mt-tRNAMet to expand codon recognition in mitochondrial translation.
NSUN3 methylase initiates 5-formylcytidine biogenesis in human mitochondrial tRNA(Met).
NSUN3-mediated mitochondrial tRNA 5-formylcytidine modification is essential for embryonic development and respiratory complexes in mice
NSUN4 is a dual function mitochondrial protein required for both methylation of 12S rRNA and coordination of mitoribosomal assembly.
NSUN6 is a human RNA methyltransferase that catalyzes formation of m5C72 in specific tRNAs.
Nuclear Magnetic Resonance Structure of the APOBEC3B Catalytic Domain: Structural Basis for Substrate Binding and DNA Deaminase Activity.
Nucleolar KKE/D repeat proteins Nop56p and Nop58p interact with Nop1p and are required for ribosome biogenesis.
Nucleolar maturation of the human small subunit processome.
Nucleotide sequence of nuclear 5.4 S RNA of mouse cells.
Nucleotide sequence of the erythromycin resistance gene of the conjugative transposon Tn1545.
Nucleotide sequence of tRNA(Thr1) of Escherichia coli and of the gene (thrV) that encodes it.
Nucleotide sequences encoding and promoting expression of three antibiotic resistance genes indigenous to Streptomyces.
N⁶-Methyladenosine Landscape of Glioma Stem-Like Cells: METTL3 Is Essential for the Expression of Actively Transcribed Genes and Sustenance of the Oncogenic Signaling.
N⁶-Methyladenosine Landscape of Glioma Stem-Like Cells: METTL3 Is Essential for theExpression of Actively Transcribed Genes and Sustenance of the Oncogenic Signaling
Oncogene c-Myc promotes epitranscriptome mA reader YTHDF1 expression in colorectal cancer.
Oncogene c-Myc promotes epitranscriptome mA reader YTHDF1 expression in colorectal cancer.
Over expression of a tRNA(Leu) isoacceptor changes charging pattern of leucine tRNAs and reveals new codon reading.
Overexpression of the thiostrepton-resistance gene from Streptomyces azureus in Escherichia coli and characterization of recognition sites of the 23S rRNA A1067 2'-methyltransferase in the guanosine triphosphatase center of 23S ribosomal RNA.
Overexpression of YTHDF1 is associated with poor prognosis in patients with hepatocellular carcinoma
Overexpression of YTHDF1 is associated with poor prognosis in patients withhepatocellular carcinoma.
Overexpression, crystallization and preliminary X-ray crystallographic analysis of Pseudomonas aeruginosa MnmE, a GTPase involved in tRNA modification.
Overview of distinct 5-methylcytosine profiles of messenger RNA in human hepatocellular carcinoma and paired adjacent non-tumor tissues.
p53 acts as a safeguard of translational control by regulating fibrillarin and rRNAmethylation in cancer.
Partial activity is seen with many substitutions of highly conserved active site residues in human Pseudouridine synthase 1.
Partial Methylation at Am100 in 18S rRNA of Baker's Yeast Reveals Ribosome Heterogeneity on the Level of Eukaryotic rRNA Modification.
PCIF1 Catalyzes m6Am mRNA Methylation to Regulate Gene Expression.
Phylogenetic analysis of the eukaryotic RNA (cytosine-5)-methyltransferases.
Phylogenomic analysis of 16S rRNA:(guanine-N2) methyltransferases suggests new family members and reveals highly conserved motifs and a domain structure similar to other nucleic acid amino-methyltransferases.
Plasmid-mediated 16S rRNA methylases among extended-spectrum beta-lactamase-producing Enterobacteriaceae isolates.
Plasticity and diversity of tRNA anticodon determinants of substrate recognition by eukaryotic A37 isopentenyltransferases.
Pmt1, a Dnmt2 homolog in Schizosaccharomyces pombe, mediates tRNA methylation in response to nutrient signaling.
Point mutations in yeast CBF5 can abolish in vivo pseudouridylation of rRNA.
Posttranscriptional modifications in the A-loop of 23S rRNAs from selected archaea and eubacteria.
Pre-steady-state kinetic analysis of the three Escherichia coli pseudouridine synthases TruB, TruA, and RluA reveals uniformly slow catalysis.
Precursor complex structure of pseudouridine synthase TruB suggests coupling of active site perturbations to an RNA-sequestering peripheral protein domain
Presence and coding properties of 2'-O-methyl-5-carbamoylmethyluridine (ncm5Um) in the wobble position of the anticodon of tRNA(Leu) (U*AA) from brewer's yeast.
Principles Governing A-to-I RNA Editing in the Breast Cancer Transcriptome.
Probing N6-methyladenosine RNA modification status at single nucleotide resolution in mRNA and long noncoding RNA.
Probing the substrate specificity of the bacterial Pnkp/Hen1 RNA repair system using synthetic RNAs.
Profiling of RNA modifications by multiplexed stable isotope labelling.
Profound downregulation of the RNA editing enzyme ADAR2 in ALS spinal motor neurons
Properties of small rRNA methyltransferase RsmD: Mutational and kinetic study.
Protection of the Queuosine Biosynthesis Enzyme QueF from Irreversible Oxidation by a Conserved Intramolecular Disulfide
Protein degradation and dynamic tRNA thiolation fine-tune translation at elevated temperatures.
Protein phosphatase methyltransferase 1 (Ppm1p) is the sole activity responsible for modification of the major forms of protein phosphatase 2A in yeast.
Proteomic analysis of the human KEOPS complex identifies C14ORF142 as a core subunit homologous to yeast Gon7.
Proteomic and 3D structure analyses highlight the C/D box snoRNP assembly mechanism and its control
Pseudouridine at position 55 in tRNA controls the contents of other modified nucleotides for low-temperature adaptation in the extreme-thermophilic eubacterium Thermus thermophilus.
Pseudouridine formation in archaeal RNAs: The case of Haloferax volcanii.
Pseudouridine mapping in the Saccharomyces cerevisiae spliceosomal U small nuclear RNAs (snRNAs) reveals that pseudouridine synthase pus1p exhibits a dual substrate specificity for U2 snRNA and tRNA.
Pseudouridine modification in Caenorhabditis elegans spliceosomal snRNAs: unique modifications are found in regions involved in snRNA-snRNA interactions.
Pseudouridine Modification Inhibits Muscleblind-like 1 (MBNL1) Binding to CCUG Repeats and Minimally Structured RNA through Reduced RNA Flexibility.
Pseudouridine synthase 1: a site-specific synthase without strict sequence recognition requirements.
Pseudouridine synthetase Pus1 of Saccharomyces cerevisiae: kinetic characterisation, tRNA structural requirement and real-time analysis of its complex with tRNA.
Pseudouridines and pseudouridine synthases of the ribosome.
Pseudouridylation at position 32 of mitochondrial and cytoplasmic tRNAs requires two distinct enzymes in Saccharomyces cerevisiae.
Pseudouridylation goes regulatory.
Pseudouridylation of tRNA-Derived Fragments Steers Translational Control in Stem Cells.
Psi35 in the branch site recognition region of U2 small nuclear RNA is important for pre-mRNA splicing in Saccharomyces cerevisiae.
Purification and cDNA cloning of the AdoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase.
Purification and characterization of the human elongator complex.
Purification, cloning, and characterization of the 16 S RNA m2G1207 methyltransferase from Escherichia coli.
Purification, cloning, and characterization of the 16S RNA m5C967 methyltransferase from Escherichia coli.
Purification, cloning, and properties of the 16S RNA pseudouridine 516 synthase from Escherichia coli.
Purification, crystallization and preliminary crystallographic analysis of the 16S rRNA methyltransferase RsmI from Escherichia coli.
Purification, structure, and properties of Escherichia coli tRNA pseudouridine synthase I.
PUS7 mutations impair pseudouridylation in humans and cause intellectual disability and microcephaly.
Pyruvate formate lyase is structurally homologous to type I ribonucleotide reductase.
Pyruvate is the source of the two carbons that are required for formation of the imidazoline ring of 4-demethylwyosine.
Qri7/OSGEPL, the mitochondrial version of the universal Kae1/YgjD protein, is essential for mitochondrial genome maintenance.
Quantitative analysis of 5HT(2C) receptor RNA editing patterns in psychiatric disorders.
Quantitative analysis of ribonucleoside modifications in tRNA by HPLC-coupled mass spectrometry.
Radical mediated ring formation in the biosynthesis of the hypermodified tRNA base wybutosine.
Radical-mediated enzymatic methylation: a tale of two SAMS.
RAM/Fam103a1 is required for mRNA cap methylation.
Rational Design of RNA Editing Guide Strands: Cytidine Analogs at the Orphan Position.
Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma.
Recognition and Cleavage of Human tRNA Methyltransferase TRMT1 by the SARS-CoV-2 Main Protease
Recognition elements in rRNA for the tylosin resistance methyltransferase RlmA(II).
Recognition of a complex substrate by the KsgA/Dim1 family of enzymes has been conserved throughout evolution.
Recombinant human mRNA cap methyltransferase binds capping enzyme/RNA polymerase IIo complexes.
Reconstituting bacterial RNA repair and modification in vitro.
Reconstitution and characterization of eukaryotic N6-threonylcarbamoylation of tRNA using a minimal enzyme system.
Reconstitution and structural analysis of the yeast box H/ACA RNA-guided pseudouridine synthase
Reconstitution and structural analysis of the yeast box H/ACA RNA-guided pseudouridine synthase.
Reduced levels of protein recoding by A-to-I RNA editing in Alzheimer's disease
Reduced m6A modification predicts malignant phenotypes and augmented Wnt/PI3K-Akt signaling in gastric cancer.
Reduced mA mRNA methylation is correlated with the progression of human cervical cancer.
Reduced misreading of asparagine codons by Escherichia coli tRNALys with hypomodified derivatives of 5-methylaminomethyl-2-thiouridine in the wobble position.
Reduction of GluR2 RNA editing, a molecular change that increases calcium influx through AMPA receptors, selective in the spinal ventral gray of patients with amyotrophic lateral sclerosis
Region-specific alterations of A-to-I RNA editing of serotonin 2c receptor in the cortex of suicides with major depression
Regulation of expression and catalytic activity of Escherichia coli RsmG methyltransferase.
Reliable Chemical Synthesis of Oligoribonucleotides (RNA) with 2′-O-[(Triisopropylsilyl)oxy]methyl(2′-O-tom)-Protected Phosphoramidites
Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins.
Requirement for IscS in biosynthesis of all thionucleosides in Escherichia coli.
Ribosomal RNA guanine-(N2)-methyltransferases and their targets.
Ribosome biogenesis factor Tsr3 is the aminocarboxypropyl transferase responsible for 18S rRNA hypermodification in yeast and humans
Rit1, a tRNA backbone-modifying enzyme that mediates initiator and elongator tRNA discrimination.
RlmCD-mediated U747 methylation promotes efficient G748 methylation by methyltransferase RlmAII in 23S rRNA in Streptococcus pneumoniae; interplay between two rRNA methylations responsible for telithr
RlmN and Cfr are radical SAM enzymes involved in methylation of ribosomal RNA
RluD, a highly conserved pseudouridine synthase, modifies 50S subunits more specifically and efficiently than free 23S rRNA.
RmtC introduces G1405 methylation in 16S rRNA and confers high-level aminoglycoside resistance on Gram-positive microorganisms.
RNA Cytidine Acetyltransferase of Small-Subunit Ribosomal RNA: Identification of Acetylation Sites and the Responsible Acetyltransferase in Fission Yeast, Schizosaccharomyces pombe.
RNA editing (R/G site) and flip–flop splicing of the AMPA receptorsubunit GluR2 in nervous tissue of epilepsy patients
RNA editing by adenosine deaminases generates RNA and protein diversity.
RNA editing in RHOQ promotes invasion potential in colorectal cancer.
RNA editing of drives early tumor invasion and metastasis in familial esophageal cancer.
RNA editing of apolipoprotein B mRNA. Sequence specificity determined by in vitrocoupled transcription editing.
RNA editing of Filamin A pre-mRNA regulates vascular contraction and diastolic blood pressure
RNA editing of the 5-HT2C receptor is reduced in schizophrenia
RNA editing of the serotonin 5HT2C receptor and its effects on cell signalling, pharmacology and brain function
RNA helicase module in an acetyltransferase that modifies a specific tRNA anticodon
RNA helicase module in an acetyltransferase that modifies a specific tRNA anticodon.
RNA helicase YTHDC2 promotes cancer metastasis via the enhancement of the efficiencyby which HIF-1α mRNA is translated.
RNA hyperediting and alternative splicing of hematopoietic cell phosphatase (PTPN6) gene in acute myeloid leukemia.
RNA m6A methyltransferase METTL3 regulates invasiveness of melanoma cells by matrixmetallopeptidase 2.
RNA mA methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail.
RNA mA Methyltransferase METTL3 Promotes The Growth Of Prostate Cancer By Regulating Hedgehog Pathway.
RNA methylation by radical SAM enzymes RlmN and Cfr proceeds via methylene transfer and hydride shift.
RNA methylation by the MIS complex regulates a cell fate decision in yeast.
RNA methylation under heat shock control.
RNA methyltransferases in plants: Breakthroughs in function and evolution
RNA methyltransferases utilize two cysteine residues in the formation of 5-methylcytosine.
RNA modification landscape of the human mitochondrial tRNA regulates protein synthesis.
RNA N6-methyladenosine demethylase FTO promotes breast tumor progression through inhibiting BNIP3.
RNA N6-methyladenosine methyltransferase-like 3 promotes liver cancer progression through YTHDF2-dependent posttranscriptional silencing of SOCS2.
RNA nucleotide methylation.
RNA recognition mechanism of eukaryote tRNA (m7G46) methyltransferase (Trm8-Trm82 complex).
RNA sequence and two-dimensional structure features required for efficient substrate modification by the Saccharomyces cerevisiae RNA:{Psi}-synthase Pus7p.
RNA-guided RNA modification: functional organization of the archaeal H/ACA RNP.
RNA-protein mutually induced fit: structure of Escherichia coli isopentenyl-tRNA transferase in complex with tRNA(Phe).
RNA-Protein Mutually Induced Fit: STRUCTURE OF ESCHERICHIA COLI ISOPENTENYL-tRNA TRANSFERASE IN COMPLEX WITH tRNA(Phe).
RNA:(guanine-N2) methyltransferases RsmC/RsmD and their homologs revisited--bioinformatic analysis and prediction of the active site based on the uncharacterized Mj0882 protein structure.
RNA:pseudouridine synthetase Pus1 from Saccharomyces cerevisiae: oligomerization property and stoichiometry of the complex with yeast tRNA(Phe).
Role of human mitochondrial Nfs1 in cytosolic iron-sulfur protein biogenesis and iron regulation.
Roles of Arabidopsis ATP/ADP isopentenyltransferases and tRNA isopentenyltransferases in cytokinin biosynthesis.
Roles of conserved amino acid sequence motifs in the SpoU (TrmH) RNA methyltransferase family.
Rrp8p is a yeast nucleolar protein functionally linked to Gar1p and involved in pre-rRNA cleavage at site A2.
rystal structure of the yeast heterodimeric ADAT2/3 deaminase.
S-Adenosyl-S-carboxymethyl-L-homocysteine: a novel cofactor found in the putative tRNA-modifying enzyme CmoA.
S-Adenosyl-S-carboxymethyl-L-homocysteine: a novel cofactor found in the putative tRNA-modifying enzyme CmoA.
S-Adenosylmethionine-dependent radical-based modification of biological macromolecules.
Saccharomyces cerevisiae Mod5p-II contains sequences antagonistic for nuclear and cytosolic locations.
SAXS analysis of the tRNA-modifying enzyme complex MnmE/MnmG reveals a novel interaction mode and GTP-induced oligomerization.
Selenium-containing tRNA(Glu) and tRNA(Lys) from Escherichia coli: purification, codon specificity and translational activity.
Selenophosphate synthetase. Enzyme properties and catalytic reaction.
Sequence analysis and overexpression of the Zymomonas mobilis tgt gene encoding tRNA-guanine transglycosylase: purification and biochemical characterization of the enzyme.
Sequence analysis and structure prediction of 23S rRNA:m1G methyltransferases reveals a conserved core augmented with a putative Zn-binding domain in the N-terminus and family-specific elaborations in the C-terminus.
Sequence analysis and structure prediction of aminoglycoside-resistance 16S rRNA:m7G methyltransferases.
Sequence analysis of a 13.4 kbp fragment from the left arm of chromosome XV reveals a malate dehydrogenase gene, a putative Ser/Thr protein kinase, the ribosomal L25 gene and four new open reading frames.
Sequence and genetic analysis of NHP2: a moderately abundant high mobility group-like nuclear protein with an essential function in Saccharomyces cerevisiae.
Sequence and properties of pIM13, a macrolide-lincosamide-streptogramin B resistance plasmid from Bacillus subtilis.
Sequence preference and structural heterogeneity of BZ junctions.
Sequence preference and structural heterogeneity of BZ junctions.
Sequence-specific and Shape-selective RNA Recognition by the Human RNA 5-Methylcytosine Methyltransferase NSun6.
Sequence-structure-function analysis of the bifunctional enzyme MnmC that catalyses the last two steps in the biosynthesis of hypermodified nucleoside mnm5s2U in tRNA.
Sequence-structure-function relationships of a tRNA (m7G46) methyltransferase studied by homology modeling and site-directed mutagenesis.
Sequence-structure-function relationships of Tgs1, the yeast snRNA/snoRNA cap hypermethylase.
Sequence-structure-function studies of tRNA:m5C methyltransferase Trm4p and its relationship to DNA:m5C and RNA:m5U methyltransferases.
Sequential 2'-O-methylation of archaeal pre-tRNATrp nucleotides is guided by the intron-encoded but trans-acting box C/D ribonucleoprotein of pre-tRNA.
Sinorhizobium meliloti YrbA binds divalent metal cations using two conserved histidines.
siRNAs compete with miRNAs for methylation by HEN1 in Arabidopsis.
Site-directed cleavage of RNA.
Site-directed mutants of 16S rRNA reveal important RNA domains for KsgA function and 30S subunit assembly.
Site-selected introduction of modified purine and pyrimidine ribonucleosides into RNA by automated phosphoramidite chemistry.
Site-specific methylation of 18S ribosomal RNA by SNORD42A is required for acutemyeloid leukemia cell proliferation.
Sites of action of two ribosomal RNA methylases responsible for resistance to aminoglycosides.
Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia.
Small-Molecule Inhibitors of METTL3, the Major Human Epitranscriptomic Writer.
Small-Molecule Inhibitors of METTL3, the Major Human Epitranscriptomic Writer.
Small-molecule modulators of TRMT2A decrease PolyQ aggregation and PolyQ-induced cell death.
Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia.
Snapshots of dynamics in synthesizing N(6)-isopentenyladenosine at the tRNA anticodon
Snapshots of dynamics in synthesizing N(6)-isopentenyladenosine at the tRNA anticodon
Snapshots of dynamics in synthesizing N(6)-isopentenyladenosine at the tRNA anticodon.
Snapshots of tRNA sulphuration via an adenylated intermediate
Snapshots of tRNA sulphuration via an adenylated intermediate
Snapshots of tRNA sulphuration via an adenylated intermediate.
Solid phase synthesis of the 5'-half of the initiator t-RNA from B. subtilis.
Solution structure of an rRNA methyltransferase (ErmAM) that confers macrolide-lincosamide-streptogramin antibiotic resistance.
Solution structure of an rRNA methyltransferase (ErmAM) that confers macrolide-lincosamide-streptogramin antibiotic resistance.
Solution structure of Kti11p from Saccharomyces cerevisiae reveals a novel zinc-binding module.
Solution structure of Kti11p from Saccharomyces cerevisiae reveals a novel zinc-binding module.
Solution structure of the RNA recognition domain of METTL3-METTL14 N6-methyladenosine methyltransferase.
Solution structure of Urm1 and its implications for the origin of protein modifiers.
Spb1p is a putative methyltransferase required for 60S ribosomal subunit biogenesis in Saccharomyces cerevisiae.
Spb1p is a yeast nucleolar protein associated with Nop1p and Nop58p that is able to bind S-adenosyl-L-methionine in vitro.
Spb1p-directed formation of Gm2922 in the ribosome catalytic center occurs at a late processing stage.
Specificity and kinetics of 23S rRNA modification enzymes RlmH and RluD.
Specificity and mechanism of RNA cap guanine-N2 methyltransferase (Tgs1).
Specificity shifts in the rRNA and tRNA nucleotide targets of archaeal and bacterial m5U methyltransferases.
SPL1-1, a Saccharomyces cerevisiae mutation affecting tRNA splicing.
Stepwise maturation of the peptidyl transferase region of human mitoribosomes.
Steroid Receptor RNA Activator (SRA) Modification by the Human Pseudouridine Synthase 1 (hPus1p): RNA Binding, Activity, and Atomic Model
Steroid Receptor RNA Activator (SRA) Modification by the Human Pseudouridine Synthase 1 (hPus1p): RNA Binding, Activity, and Atomic Model
Steroid receptor RNA activator (SRA) modification by the human pseudouridine synthase 1 (hPus1p): RNA binding, activity, and atomic model.
Stresses that Raise NpA Levels Induce Protective Nucleoside Tetraphosphate Capping of Bacterial RNA.
Structural alterations of the cysteine desulfurase IscS of Salmonella enterica serovar Typhimurium reveal substrate specificity of IscS in tRNA thiolation.
Structural analyses of NudT16-ADP-ribose complexes direct rational design of mutants with improved processing of poly(ADP-ribosyl)ated proteins.
Structural analyses of NudT16-ADP-ribose complexes direct rational design of mutants with improved processing of poly(ADP-ribosyl)ated proteins.
Structural analysis of human 2'-O-ribose methyltransferases involved in mRNA cap structure formation.
Structural analysis of human 2'-O-ribose methyltransferases involved in mRNA cap structure formation.
Structural analysis of the activation-induced deoxycytidine deaminase required in immunoglobulin diversification.
Structural analysis of the essential resuscitation promoting factor YeaZ suggests a mechanism of nucleotide regulation through dimer reorganization.
Structural analysis of the SARS-CoV-2 methyltransferase complex involved in RNA cap creation bound to sinefungin.
Structural and biochemical insights into 2'-O-methylation at the 3'-terminal nucleotide of RNA by Hen1.
Structural and biochemical insights into 2'-O-methylation at the 3'-terminal nucleotide of RNA by Hen1.
Structural and catalytic analyses of the InsP 6 kinase activities of higher plant ITPKs.
Structural and catalytic roles of the human 18SrRNA methyltransferases DIMT1 in ribosome assembly and translation
Structural and Dynamic Insights into Redundant Function of YTHDF Proteins.
Structural and evolutionary bioinformatics of the SPOUT superfamily of methyltransferases.
Structural and functional characterization of KEOPS dimerization by Pcc1 and its role in t6A biosynthesis
Structural and functional characterization of Rv2966c protein reveals an RsmD-like methyltransferase from Mycobacterium tuberculosis and the role of its N-terminal domain in target recognition
Structural and functional characterization of Rv2966c protein reveals an RsmD-like methyltransferase from Mycobacterium tuberculosis and the role of its N-terminal domain in target recognition.
Structural and functional divergence within the Dim1/KsgA family of rRNA methyltransferases.
Structural and functional divergence within the Dim1/KsgA family of rRNA methyltransferases.
Structural and functional divergence within the Dim1/KsgA family of rRNA methyltransferases.
Structural and functional evidence of high specificity of Cbf5 for ACA trinucleotide.
Structural and functional insights into human tRNA guanine transgylcosylase
Structural and functional insights into the molecular mechanism of rRNA m6A methyltransferase RlmJ.
Structural and Functional Insights Into the Molecular Mechanism of Rrna M6A Methyltransferase Rlmj.
Structural and Functional Insights Into the Molecular Mechanism of Rrna M6A Methyltransferase Rlmj.
Structural and functional insights into tRNA binding and adenosine N1-methylation by an archaeal Trm10 homologue.
Structural and Functional Insights Into tRNA Binding and Adenosine N1-Methylation by an Archaeal Trm10 Homologue.
Structural and Functional Insights Into tRNA Binding and Adenosine N1-Methylation by an Archaeal Trm10 Homologue.
Structural and functional studies of Bud23-Trm112 reveal 18S rRNA N7-G1575 methylation occurs on late 40S precursor ribosomes
Structural and functional studies of Bud23-Trm112 reveal 18S rRNA N7-G1575 methylation occurs on late 40S precursor ribosomes.
Structural and functional studies of the Thermus thermophilus 16S rRNA methyltransferase RsmG
Structural and functional studies of the Thermus thermophilus 16S rRNA methyltransferase RsmG
Structural and functional studies of the Thermus thermophilus 16S rRNA methyltransferase RsmG.
Structural and kinetic characterization of Escherichia coli TadA, the wobble-specific tRNA deaminase.
Structural and kinetic characterization of Escherichia coli TadA, the wobble-specific tRNA deaminase.
Structural and mechanistic basis of mammalian Nudt12 RNA deNADding.
Structural and thermodynamic evidence for a stabilizing role of Nop5p in S-adenosyl-L-methionine binding to fibrillarin.
Structural bases for 16 S rRNA methylation catalyzed by ArmA and RmtB methyltransferases
Structural bases for 16 S rRNA methylation catalyzed by ArmA and RmtB methyltransferases
Structural bases for 16 S rRNA methylation catalyzed by ArmA and RmtB methyltransferases.
Structural basis for binding of RNA and cofactor by a KsgA methyltransferase.
Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases.
Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases.
Structural basis for Fe-S cluster assembly and tRNA thiolation mediated by IscS protein-protein interactions.
Structural basis for Fe-S cluster assembly and tRNA thiolation mediated by IscS protein-protein interactions.
Structural basis for Fe-S cluster assembly and tRNA thiolation mediated by IscS protein-protein interactions.
Structural basis for hypermodification of the wobble uridine in tRNA by bifunctional enzyme MnmC.
Structural basis for hypermodification of the wobble uridine in tRNA by bifunctional enzyme MnmC.
Structural basis for inhibition of the fat mass and obesity associated protein (FTO)
Structural basis for late maturation steps of the human mitoribosomal large subunit.
Structural basis for lysidine formation by ATP pyrophosphatase accompanied by a lysine-specific loop and a tRNA-recognition domain.
Structural basis for lysidine formation by ATP pyrophosphatase accompanied by a lysine-specific loop and a tRNA-recognition domain.
Structural basis for m7G-cap hypermethylation of small nuclear, small nucleolar and telomerase RNA by the dimethyltransferase TGS1.
Structural basis for m7G-cap hypermethylation of small nuclear, small nucleolar and telomerase RNA by the dimethyltransferase TGS1.
Structural basis for methyl transfer by a radical SAM enzyme.
Structural basis for methyl transfer by a radical SAM enzyme.
Structural basis for METTL6-mediated m3C RNA methylation.
Structural basis for nucleotide recognition by the ectoenzyme CD203c.
Structural basis for recognition of human 7SK long noncoding RNA by the La-related protein Larp7.
Structural Basis for Regulation of METTL16, an S-Adenosylmethionine Homeostasis Factor.
Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase.
Structural basis for site-specific ribose methylation by box C/D RNA protein complexes.
Structural basis for site-specific ribose methylation by box C/D RNA protein complexes.
Structural basis for substrate binding and catalytic mechanism of a human RNA:m5C methyltransferase NSun6
Structural basis for substrate binding and catalytic mechanism of a human RNA:m5C methyltransferase NSun6.
Structural basis for substrate placement by an archaeal box C/D ribonucleoprotein particle.
Structural basis for substrate placement by an archaeal box C/D ribonucleoprotein particle.
Structural basis for substrate placement by an archaeal box C/D ribonucleoprotein particle.
Structural Basis for Sulfur Relay to RNA Mediated by Heterohexameric TusBCD Complex
Structural basis for sulfur relay to RNA mediated by heterohexameric TusBCD complex.
Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B.
Structural Basis for the Discriminative Recognition of N6-Methyladenosine RNA by the Human YT521-B Homology Domain Family of Proteins.
Structural basis for the dual U4 and U4atac snRNA-binding specificity of spliceosomal protein hPrp31.
Structural basis for the methylation of A1408 in 16S rRNA by a panaminoglycoside resistance methyltransferase NpmA from a clinical isolate and analysis of the NpmA interactions with the 30S ribosomal subunit.
Structural basis for the methylation of A1408 in 16S rRNA by a panaminoglycoside resistance methyltransferase NpmA from a clinical isolate and analysis of the NpmA interactions with the 30S ribosomal subunit.
Structural basis for the methylation of A1408 in 16S rRNA by a panaminoglycoside resistance methyltransferase NpmA from a clinical isolate and analysis of the NpmA interactions with the 30S ribosomal subunit.
Structural basis for the methylation of G1405 in 16S rRNA by aminoglycoside resistance methyltransferase Sgm from an antibiotic producer: a diversity of active sites in m7G methyltransferases.
Structural basis for the methylation of G1405 in 16S rRNA by aminoglycoside resistance methyltransferase Sgm from an antibiotic producer: a diversity of active sites in m7G methyltransferases.
Structural basis for the methylation of G1405 in 16S rRNA by aminoglycoside resistance methyltransferase Sgm from an antibiotic producer: a diversity of active sites in m7G methyltransferases.
Structural Basis for the Specificity of Human Nudt16 and its Regulation by Inosine Monophosphate.
Structural basis for translational fidelity ensured by transfer RNA lysidine synthetase.
Structural basis for translational fidelity ensured by transfer RNA lysidine synthetase.
Structural basis of 7SK RNA 5'-gamma-phosphate methylation and retention by MePCE.
Structural basis of AdoMet-dependent aminocarboxypropyl transfer reaction catalyzed by tRNA-wybutosine synthesizing enzyme, TYW2
Structural basis of AdoMet-dependent aminocarboxypropyl transfer reaction catalyzed by tRNA-wybutosine synthesizing enzyme, TYW2
Structural basis of AdoMet-dependent aminocarboxypropyl transfer reaction catalyzed by tRNA-wybutosine synthesizing enzyme, TYW2.
Structural basis of antagonism of human APOBEC3F by HIV-1 Vif.
Structural Basis of Biological Nitrile Reduction.
Structural basis of biological nitrile reduction.
Structural basis of dcp2 recognition and activation by dcp1
Structural basis of DNA binding to human YB-1 cold shock domain regulated by phosphorylation.
Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling.
Structural basis of mismatch recognition by a SARS-CoV-2 proofreading enzyme.
Structural basis of mRNA-cap recognition by Dcp1-Dcp2.
Structural basis of N6-adenosine methylation by the METTL3-METTL14 complex
Structural basis of nucleic acid recognition and 6mA demethylation by human ALKBH1.
Structural basis of prokaryotic NAD-RNA decapping by NudC
Structural basis of regulated m 7 G tRNA modification by METTL1-WDR4.
Structural basis of RNA conformational switching in the transcriptional regulator 7SK RNP.
Structural basis of RNA processing by human mitochondrial RNase P
Structural basis of tRNA agmatinylation essential for AUA codon decoding
Structural basis of tRNA agmatinylation essential for AUA codon decoding
Structural basis of tRNA agmatinylation essential for AUA codon decoding.
Structural basis of tRNA modification with CO2 fixation and methylation by wybutosine synthesizing enzyme TYW4.
Structural basis of tRNA modification with CO2 fixation and methylation by wybutosine synthesizing enzyme TYW4.
Structural bioinformatics analysis of enzymes involved in the biosynthesis pathway of the hypermodified nucleoside ms(2)io(6)A37 in tRNA.
Structural characterization of B. subtilis m1A22 tRNA methyltransferase TrmK: insights into tRNA recognition
Structural characterization of glycinamide-RNase-transformylase T fromMycobacterium tuberculosis.
Structural comparison of tRNA m(1)A58 methyltransferases revealed different molecular strategies to maintain their oligomeric architecture under extreme conditions.
Structural comparison of yeast snoRNP and spliceosomal protein Snu13p with its homologs
Structural Consequences of Nucleophosmin Mutations in Acute Myeloid Leukemia.
Structural determinants of APOBEC3B non-catalytic domain for molecular assembly and catalytic regulation.
Structural determinants of HIV-1 Vif susceptibility and DNA binding in APOBEC3F.
Structural features of the guide:target RNA duplex required for archaeal box C/D sRNA-guided nucleotide 2'-O-methylation.
Structural Insight Into hnRNP A2/B1 Homodimerization and DNA Recognition.
Structural insight into human N6amt1-Trm112 complex functioning as a protein methyltransferase.
Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis.
Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis.
Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis.
Structural insight into the mechanism of stabilization of the 7SK small nuclear RNA by LARP7.
Structural insight into the methyltransfer mechanism of the bifunctional Trm5
Structural insights into actin filament recognition by commonly used cellular actin markers
Structural insights into dimethylation of 12S rRNA by TFB1M: indispensable role in translation of mitochondrial genes and mitochondrial function.
Structural insights into dimethylation of 12S rRNA by TFB1M: indispensable role in translation of mitochondrial genes and mitochondrial function.
Structural insights into dimethylation of 12S rRNA by TFB1M: indispensable role in translation of mitochondrial genes and mitochondrial function.
Structural insights into dpCoA-RNA decapping by NudC.
Structural insights into FTO's catalytic mechanism for the demethylation of multiple RNA substrates
Structural Insights into HIV-1 Vif-APOBEC3F Interaction.
Structural insights into mechanisms of the small RNA methyltransferase HEN1.
Structural insights into mechanisms of the small RNA methyltransferase HEN1.
Structural Insights Into Methyltransferase Ksga Function in 30S Ribosomal Subunit Biogenesis
Structural insights into methyltransferase KsgA function in 30S ribosomal subunit biogenesis.
Structural insights into the catalytic mechanism of Escherichia coli selenophosphate synthetase.
Structural insights into the function of 23S rRNA methyltransferase RlmG (m2G1835) from Escherichia coli
Structural insights into the function of aminoglycoside-resistance A1408 16S rRNA methyltransferases from antibiotic-producing and human pathogenic bacteria.
Structural insights into the function of aminoglycoside-resistance A1408 16S rRNA methyltransferases from antibiotic-producing and human pathogenic bacteria.
Structural insights into the GTPase domain of Escherichia coli MnmE protein.
Structural Insights into the Methylation of C1402 in 16S rRNA by Methyltransferase RsmI
Structural insights into the molecular mechanism of the m(6)A writer complex.
Structural insights into the molecular mechanism of the m(6)A writer complex.
Structural insights into the RNA methyltransferase domain of METTL16.
Structural insights into the stimulation of S. pombe Dnmt2 catalytic efficiency by the tRNA nucleoside queuosine.
Structural Investigations on the Interactions between Cytidine Deaminase Human APOBEC3G and DNA.
Structural Investigations on the Interactions between Cytidine Deaminase Human APOBEC3G and DNA.
Structural mechanism of substrate RNA recruitment in H/ACA RNA-guided pseudouridine synthase.
Structural model of the M7G46 Methyltransferase TrmB in complex with tRNA
Structural organization of box C/D RNA-guided RNA methyltransferase.
Structural organization of box C/D RNA-guided RNA methyltransferase.
Structural rearrangements in the active site of the Thermus thermophilus 16S rRNA methyltransferase KsgA in a binary complex with 5'-methylthioadenosine.
Structural rearrangements in the active site of the Thermus thermophilus 16S rRNA methyltransferase KsgA in a binary complex with 5'-methylthioadenosine.
Structural rearrangements in the active site of the Thermus thermophilus 16S rRNA methyltransferase KsgA in a binary complex with 5'-methylthioadenosine.
Structural study of the H/ACA snoRNP components Nop10p and the 3' hairpin of U65 snoRNA
Structural study of the H/ACA snoRNP components Nop10p and the 3' hairpin of U65 snoRNA.
Structure analysis of the conserved methyltransferase domain of human trimethylguanosine synthase TGS1.
Structure analysis of the conserved methyltransferase domain of human trimethylguanosine synthase TGS1.
Structure and function of archaeal box C/D sRNP core proteins.
Structure and function of archaeal box C/D sRNP core proteins.
Structure and function of the antibiotic resistance-mediating methyltransferase AviRb from Streptomyces viridochromogenes
Structure and function of the antibiotic resistance-mediating methyltransferase AviRb from Streptomyces viridochromogenes.
Structure and function of the bacterial decapping enzyme NudC
Structure and function of the bacterial decapping enzyme NudC.
Structure and function of the NS5 methyltransferase domain from Usutu virus
Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex.
Structure and mechanism of yeast RNA triphosphatase: an essential component of the mRNA capping apparatus.
Structure and mechanism of yeast RNA triphosphatase: an essential component of the mRNA capping apparatus.
Structure and mechanism of yeast RNA triphosphatase: an essential component of the mRNA capping apparatus.
Structure and organization of Escherichia coli genes involved in biosynthesis of the deazaguanine derivative queuine, a nutrient factor for eukaryotes.
Structure and regulation of ZCCHC4 in m6A-methylation of 28S rRNA.
Structure and regulation of ZCCHC4 in mA-methylation of 28S rRNA.
Structure determination of fibrillarin from the hyperthermophilic archaeon Pyrococcus furiosus.
Structure determination of two new amino acid-containing derivatives of adenosine from tRNA of thermophilic bacteria and archaea.
Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA
Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA
Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA.
Structure of a pre-catalytic spliceosome.
Structure of a reaction intermediate mimic in t6A biosynthesis bound in the active site of the TsaBD heterodimer from Escherichia coli.
Structure of a TrmA-RNA complex: A consensus RNA fold contributes to substrate selectivity and catalysis in m5U methyltransferases.
Structure of a TrmA-RNA complex: A consensus RNA fold contributes to substrate selectivity and catalysis in m5U methyltransferases.
Structure of active human telomerase with telomere shelterin protein TPP1.
Structure of an archaeal TYW1, the enzyme catalyzing the second step of wye-base biosynthesis
Structure of an archaeal TYW1, the enzyme catalyzing the second step of wye-base biosynthesis.
Structure of an essential bacterial protein YeaZ (TM0874) from Thermotoga maritima at 2.5 A resolution.
Structure of D-tyrosyl-tRNATyr deacylase using home-source Cu Kalpha and moderate-quality iodide-SAD data: structural polymorphism and HEPES-bound enzyme states
Structure of dihydrouridine synthase C (DusC) from Escherichia coli
Structure of dihydrouridine synthase C (DusC) from Escherichia coli.
Structure of H/ACA RNP protein Nhp2p reveals cis/trans isomerization of a conserved proline at the RNA and Nop10 binding interface.
Structure of H/ACA RNP Protein Nhp2p Reveals Cis/Trans Isomerization of a Conserved Proline at the RNA and Nop10 Binding Interface.
Structure of human DNMT2, an enigmatic DNA methyltransferase homolog that displays denaturant-resistant binding to DNA.
Structure of human DNMT2, an enigmatic DNA methyltransferase homolog that displays denaturant-resistant binding to DNA.
Structure of human Fe-S assembly subcomplex reveals unexpected cysteine desulfurase architecture and acyl-ACP-ISD11 interactions.
Structure of human RNA N6-methyladenine demethylase ALKBH5 provides insights into its mechanisms of nucleic acid recognition and demethylation.
Structure of human RNA N6-methyladenine demethylase ALKBH5 provides insights into its mechanisms of nucleic acid recognition and demethylation.
Structure of human telomerase holoenzyme with bound telomeric DNA.
Structure of Nucleophosmin DNA-binding Domain and Analysis of Its Complex with a G-quadruplex Sequence from the c-MYC Promoter.
Structure of protein L7Ae bound to a K-turn derived from an archaeal box H/ACA sRNA at 1.8 A resolution.
Structure of Protein L7Ae Bound to a K-Turn Derived from an Archaeal Box H/ACA sRNA at 1.8 A Resolution.
Structure of Saccharomyces cerevisiae mitochondrial Qri7 in complex with AMP
Structure of Saccharomyces cerevisiae mitochondrial Qri7 in complex with AMP.
Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP.
Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP.
Structure of the archaeal Kae1/Bud32 fusion protein MJ1130: a model for the eukaryotic EKC/KEOPS subcomplex.
Structure of the bifunctional methyltransferase YcbY (RlmKL) that adds the m7G2069 and m2G2445 modifications in Escherichia coli 23S rRNA
Structure of the bifunctional methyltransferase YcbY (RlmKL) that adds the m7G2069 and m2G2445 modifications in Escherichia coli 23S rRNA.
Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation.
Structure of the DNA deaminase domain of the HIV-1 restriction factor APOBEC3G.
Structure of the Essential MTERF4:NSUN4 Protein Complex Reveals How an MTERF Protein Collaborates to Facilitate rRNA Modification.
Structure of the guanylyltransferase domain of human mRNA capping enzyme.
Structure of the guanylyltransferase domain of human mRNA capping enzyme.
Structure of the human frataxin-bound iron-sulfur cluster assembly complex provides insight into its activation mechanism.
Structure of the human MTERF4-NSUN4 protein complex that regulates mitochondrial ribosome biogenesis.
Structure of the human MTERF4-NSUN4 protein complex that regulates mitochondrial ribosome biogenesis.
Structure of the Kti11/Kti13 Heterodimer and Its Double Role in Modifications of tRNA and Eukaryotic Elongation Factor 2.
Structure of the Kti11/Kti13 Heterodimer and its Double Role in Modifications of tRNA and Eukaryotic Elongation Factor 2.
Structure of the Kti11/Kti13 Heterodimer and its Double Role in Modifications of tRNA and Eukaryotic Elongation Factor 2.
Structure of the Lifeact-F-actin complex
Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome.
Structure of the pseudouridine synthase RsuA from Haemophilus influenzae.
Structure of the RNA 3'-phosphate cyclase-adenylate intermediate illuminates nucleotide specificity and covalent nucleotidyl transfer.
Structure of the RNA-dependent RNA polymerase from COVID-19 virus.
Structure of the Saccharomyces cerevisiae Cet1-Ceg1 mRNA capping apparatus.
Structure of the Saccharomyces cerevisiae Cet1-Ceg1 mRNA Capping Apparatus.
Structure of the Saccharomyces cerevisiae Hrr25:Mam1 monopolin subcomplex reveals a novel kinase regulator.
Structure of the Saccharomyces cerevisiae Hrr25:Mam1 monopolin subcomplex reveals a novel kinase regulator.
Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors.
Structure of the Shq1-Cbf5-Nop10-Gar1 complex and implications for H/ACA RNP biogenesis and dyskeratosis congenita
Structure of the Shq1-Cbf5-Nop10-Gar1 complex and implications for H/ACA RNP biogenesis and dyskeratosis congenita.
Structure of the thiostrepton resistance methyltransferase.S-adenosyl-L-methionine complex and its interaction with ribosomal RNA.
Structure of the thiostrepton-resistance methyltransferase-S-adenosyl-L-methionine complex and its interaction with ribosomal RNA
Structure of the yeast tRNA m7G methylation complex.
Structure of the Yeast tRNA M7G Methylation Complex.
Structure of the YTH domain of human YTHDF2 in complex with an m(6)A mononucleotide reveals an aromatic cage for m(6)A recognition.
Structure of tRNA dimethylallyltransferase: RNA modification through a channel.
Structure of tRNA methyltransferase complex of Trm7 and Trm734 reveals a novel binding interface for tRNA recognition.
Structure of tRNA Pseudouridine Synthase TruB and Its RNA Complex: RNA Recognition Through a Combination of Rigid Docking and Induced Fit
Structure of tRNA pseudouridine synthase TruB and its RNA complex: RNA recognition through a combination of rigid docking and induced fit.
Structure of wye (Yt base) and wyosine (Yt) from Torulopsis utilis phenylalanine transfer ribonucleic acid.
Structure prediction and phylogenetic analysis of a functionally diverse family of proteins homologous to the MT-A70 subunit of the human mRNA:m(6)A methyltransferase.
Structure, biosynthesis, and function of queuosine in transfer RNA.
Structure, interaction and real-time monitoring of the enzymatic reaction of wild-type APOBEC3G
Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase.
Structure-Activity Relationships and Antileukemia Effects of the Tricyclic Benzoic Acid FTO Inhibitors
Structure-Based Design of Selective Fat Mass and Obesity Associated Protein (FTO) Inhibitors
Structure-function analysis of Escherichia coli MnmG (GidA), a highly conserved tRNA-modifying enzyme.
Structure-function analysis of human TYW2 enzyme required for the biosynthesis of a highly modified Wybutosine (yW) base in phenylalanine-tRNA.
Structure-function analysis of the mRNA cap methyltransferase of Saccharomyces cerevisiae.
Structure-function analysis of yeast piD261/Bud32, an atypical protein kinase essential for normal cell life.
Structure-guided discovery of the metabolite carboxy-SAM that modulates tRNA function
Structure-guided discovery of the metabolite carboxy-SAM that modulates tRNA function.
Structures and mechanisms of tRNA methylation by METTL1-WDR4.
Structures of a putative RNA 5-methyluridine methyltransferase, Thermus thermophilus TTHA1280, and its complex with S-adenosyl-L-homocysteine.
Structures of human ADAR2 bound to dsRNA reveal base-flipping mechanism and basis for site selectivity.
Structures of human ALKBH5 demethylase reveal a unique binding mode for specific single stranded m6A RNA demethylation.
Structures of human ALKBH5 demethylase reveal a unique binding mode for specific single-stranded N6-methyladenosine RNA demethylation.
Structures of human ALKBH5 demethylase reveal a unique binding mode for specific single-stranded N6-methyladenosine RNA demethylation.
Structures of RNA 3'-phosphate cyclase bound to ATP reveal the mechanism of nucleotidyl transfer and metal-assisted catalysis.
Structures of RNA 3'-phosphate cyclase bound to ATP reveal the mechanism of nucleotidyl transfer and metal-assisted catalysis.
Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation
Structures of the human pre-catalytic spliceosome and its precursor spliceosome.
Studies on polynucleotides, lxviii the primary structure of yeast phenylalanine transfer RNA.
Studies on the function of two adjacent N6,N6-dimethyladenosines near the 3' end of 16 S ribosomal RNA of Escherichia coli. III. Purification and properties of the methylating enzyme and methylase-30 S interactions.
Studies on the function of two adjacent N6,N6-dimethyladenosines near the 3' end of 16S ribosomal RNA of Escherichia coli. IV. The effect of the methylgroups on ribosomal subunit interaction.
Substitutions in an active site loop of Escherichia coli IscS result in specific defects in Fe-S cluster and thionucleoside biosynthesis in vivo.
Substrate binding analysis of the 23S rRNA methyltransferase RrmJ.
Substrate Recognition and Modification by the Nosiheptide Resistance Methyltransferase
Substrate recognition of tRNA (Guanosine-2'-)-methyltransferase from Thermus thermophilus HB27.
Substrate requirements for ErmC' methyltransferase activity.
Substrate RNA positioning in the archaeal H/ACA ribonucleoprotein complex
Substrate specificity and properties of the Escherichia coli 16S rRNA methyltransferase, RsmE.
Substrate specificity of the pseudouridine synthase RluD in Escherichia coli.
Substrate tRNA recognition mechanism of a multisite-specific tRNA methyltransferase, Aquifex aeolicus Trm1, based on the X-ray crystal structure
Substrate tRNA recognition mechanism of a multisite-specific tRNA methyltransferase, Aquifex aeolicus Trm1, based on the X-ray crystal structure
Substrate tRNA recognition mechanism of a multisite-specific tRNA methyltransferase, Aquifex aeolicus Trm1, based on the X-ray crystal structure.
Substrate tRNA recognition mechanism of eubacterial tRNA (m1A58) methyltransferase (TrmI).
SufA/IscA: reactivity studies of a class of scaffold proteins involved in [Fe-S] cluster assembly.
Suppression of mA reader Ythdf2 promotes hematopoietic stem cell expansion.
Switching Demethylation Activities between AlkB Family RNA/DNA Demethylases through Exchange of Active-Site Residues.
Synthesis and Characterization of the Native Anticodon Domain of E. coli tRNALys: Simultaneous Incorporation of Modified Nucleosides mnm5s2U, t6A, and Pseudouridine Using Phosphoramidite Chemistry
Synthesis and hybridization studies on two complementary nona(2'-O-methyl)ribonucleotides.
Synthesis and Incorporation of 2′-O-Methyl-Pseudouridine into Oligonucleotides
Synthesis and properties of 2'-O-methyl-2-thiouridine and oligoribonucleotides containing 2'-O-methyl-2-thiouridine.
Synthesis and studies on the effect of 2-thiouridine and 4-thiouridine on sugar conformation and RNA duplex stability.
Synthesis of 2′-O-[(Triisopropylsilyl)oxy]methyl (= tom)-Protected Ribonucleoside Phosphoramidites Containing Various Nucleobase Analogues
Synthesis of a 3-methyluridine phosphoramidite to investigate the role of methylation in a ribosomal RNA hairpin.
Synthesis of helix 69 of Escherichia coli 23S rRNA containing its natural modified nucleosides, m(3)Psi and Psi.
Synthesis of modified nucleosides for the incorporation into tRNAs
Synthesis of N-Methylated Ribonucleosides for RNA Synthesis
Synthesis of the Anticodon Hairpin tRNAfMet Containing N-{[9-(β-D-Ribofuranosyl)-9H-purin-6-yl]carbamoyl}-L-threonine (=N6-{{[(1S,2R)-1-Carboxy-2-hydroxypropyl]amino}carbonyl}adenosine, t6A)
Synthesis of the tRNALys,3 Anticodon Stem-Loop Domain Containing the Hypermodified ms2t6A Nucleoside
Synthesis, base pairing properties and trans-lesion synthesis by reverse transcriptases of oligoribonucleotides containing the oxidatively damaged base 5-hydroxycytidine.
Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.
Tad1p, a yeast tRNA-specific adenosine deaminase, is related to the mammalian pre-mRNA editing enzymes ADAR1 and ADAR2.
tadA, an essential tRNA-specific adenosine deaminase from Escherichia coli.
Target recognition, RNA methylation activity and transcriptional regulation of the Dictyostelium discoideum Dnmt2-homologue (DnmA)
Targeting the RNA m(6)A Reader YTHDF2 Selectively Compromises Cancer Stem Cells inAcute Myeloid Leukemia.
Taurine as a constituent of mitochondrial tRNAs: new insights into the functions of taurine and human mitochondrial diseases.
Taurine-containing uridine modifications in tRNA anticodons are required to decipher non-universal genetic codes in ascidian mitochondria
Temperature sensitive nop2 alleles defective in synthesis of 25S rRNA and large ribosomal subunits in Saccharomyces cerevisiae.
Tertiary network in mammalian mitochondrial tRNAAsp revealed by solution probing and phylogeny.
Tertiary structure checkpoint at anticodon loop modification in tRNA functional maturation
Tertiary structure checkpoint at anticodon loop modification in tRNA functional maturation.
Tertiary structure checkpoint at anticodon loop modification in tRNA functional maturation.
The 18S ribosomal RNA m6 A methyltransferase Mettl5 is required for normal walking behavior in Drosophila.
The 18S rRNA dimethylase Dim1p is required for pre-ribosomal RNA processing in yeast.
The 2'-O-methyltransferase responsible for modification of yeast tRNA at position 4.
The 2-thiouridylase function of the human MTU1 (TRMU) enzyme is dispensable for mitochondrial translation.
The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism.
The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism.
The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism.
The 3.8 angstrom structure of the U4/U6.U5 tri-snRNP: Insights into spliceosome assembly and catalysis
The activity of an ancient atypical protein kinase is stimulated by ADP-ribose in vitro.
The ADAR protein family
The Alazami Syndrome-Associated Protein LARP7 Guides U6 Small Nuclear RNA Modification and Contributes to Splicing Robustness.
The AlkB domain of mammalian ABH8 catalyzes hydroxylation of 5-methoxycarbonylmethyluridine at the wobble position of tRNA.
The aminoglycoside resistance methyltransferase Sgm impedes RsmF methylation at an adjacent rRNA nucleotide in the ribosomal A site.
The Antiviral and Cancer Genomic DNA Deaminase APOBEC3H Is Regulated by an RNA-Mediated Dimerization Mechanism.
The ApaH-like phosphatase TbALPH1 is the major mRNA decapping enzyme of trypanosomes
The APOBEC-2 crystal structure and functional implications for the deaminase AID.
The APOBEC3C crystal structure and the interface for HIV-1 Vif binding.
The archaeal COG1901/DUF358 SPOUT-methyltransferase members, together with pseudouridine synthase Pus10, catalyze the formation of 1-methylpseudouridine at position 54 of tRNA.
The archaeon Haloarcula marismortui has few modifications in the central parts of its 23S ribosomal RNA.
The Association Between the FTO rs9939609 Variant and Malignant Pleural Mesothelioma Risk: A Case-Control Study.
The ATP-mediated formation of the YgjD-YeaZ-YjeE complex is required for the biosynthesis of tRNA t6A in Escherichia coli
The ATPase activity of an 'essential' Bacillus subtilis enzyme, YdiB, is required for its cellular function and is modulated by oligomerization.
The avilamycin resistance determinants AviRa and AviRb methylate 23S rRNA at the guanosine 2535 base and the uridine 2479 ribose.
The Bacillus subtilis open reading frame ysgA encodes the SPOUT methyltransferase RlmP forming 2'- O-methylguanosine at position 2553 in the A-loop of 23S rRNA
The bipartite structure of the tRNA m1A58 methyltransferase from S. cerevisiae is conserved in humans.
The Bowen-Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Psi1191 in yeast 18S rRNA.
The box H + ACA snoRNAs carry Cbf5p, the putative rRNA pseudouridine synthase.
The box H/ACA ribonucleoprotein complex: interplay of RNA and protein structures in post-transcriptional RNA modification.
The box H/ACA RNP assembly factor Naf1p contains a domain homologous to Gar1p mediating its interaction with Cbf5p.
The C-terminal end of the Trypanosoma brucei editing deaminase plays a critical role in tRNA binding.
The carboxyl-terminal extension of yeast tRNA m5C methyltransferase enhances the catalytic efficiency of the amino-terminal domain.
The catalytic domain of topological knot tRNA methyltransferase (TrmH) discriminates between substrate tRNA and non-substrate tRNA via an induced-fit process.
The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs.
The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs.
The Cm56 tRNA modification in archaea is catalyzed either by a specific 2'-O-methylase, or a C/D sRNP.
The coiled-coil domain of the Nop56/58 core protein is dispensable for sRNP assembly but is critical for archaeal box C/D sRNP-guided nucleotide methylation.
The complete set of H/ACA snoRNAs that guide rRNA pseudouridylations in Saccharomyces cerevisiae.
The complete set of tRNA species in Nanoarchaeum equitans.
The complete structure of small.subunit processome
The complete structure of the small-subunit processome.
The conformation of 23S rRNA nucleotide A2058 determines its recognition by the ErmE methyltransferase.
The conserved Cys-X1-X2-Cys motif present in the TtcA protein is required for the thiolation of cytidine in position 32 of tRNA from Salmonella enterica serovar Typhimurium.
The conserved Wobble uridine tRNA thiolase Ctu1-Ctu2 is required to maintain genome integrity.
The critical function of the plastid rRNA methyltransferase, CMAL, in ribosome biogenesis and plant development.
The crystal structure and small-angle X-ray analysis of CsdL/TcdA reveal a new tRNA binding motif in the MoeB/E1 superfamily.
The Crystal Structure and Small-Angle X-Ray Analysis of Csdl/Tcda Reveal a New tRNA Binding Motif in the Moeb/E1 Superfamily.
The crystal structure of E. coli rRNA pseudouridine synthase RluE.
The Crystal Structure of E. coli rRNA Pseudouridine Synthase RluE.
The crystal structure of Nep1 reveals an extended SPOUT-class methyltransferase fold and a pre-organized SAM-binding site.
The crystal structure of Nep1 reveals an extended SPOUT-class methyltransferase fold and a pre-organized SAM-binding site.
The crystal structure of Pyrococcus abyssi tRNA (uracil-54, C5)-methyltransferase provides insights into its tRNA specificity.
The Crystal Structure of Pyrococcus Abyssi tRNA (Uracil-54, C5)-Methyltransferase Provides Insights Into its tRNA Specificity.
The Crystal Structure of Pyrococcus Abyssi tRNA (Uracil-54, C5)-Methyltransferase Provides Insights Into its tRNA Specificity.
The crystal structure of the lysyl-tRNA synthetase (LysU) from Escherichia coli
The crystal structure of the lysyl-tRNA synthetase (LysU) from Escherichia coli.
The crystal structure of the Methanocaldococcus jannaschii multifunctional L7Ae RNA-binding protein reveals an induced-fit interaction with the box C/D RNAs.
The crystal structure of the Methanocaldococcus jannaschii multifunctional L7Ae RNA-binding protein reveals an induced-fit interaction with the box C/D RNAs.
The Crystal Structure of the Methanocaldococcus jannaschii Multifunctional L7Ae RNA-Binding Protein Reveals an Induced-Fit Interaction with the Box C/D RNAs.
The crystal structure of the Pyrococcus abyssi mono-functional methyltransferase PaTrm5b
The Crystal Structure of the Z[beta] Domain of the RNA-editing Enzyme ADAR1 Reveals Distinct Conserved Surfaces Among Z-domains.
The cysteine desulfurase IscS is required for synthesis of all five thiolated nucleosides present in tRNA from Salmonella enterica serovar typhimurium.
The deazapurine biosynthetic pathway revealed: in vitro enzymatic synthesis of PreQ(0) from guanosine 5'-triphosphate in four steps.
The DIM1 gene responsible for the conserved m6(2)Am6(2)A dimethylation in the 3'-terminal loop of 18 S rRNA is essential in yeast.
The Dnmt2 RNA methyltransferase homolog of Geobacter sulfurreducens specifically methylates tRNA-Glu.
The effect of FTO rs9939609 on major depression differs across MDD subtypes.
The effect of FTO rs9939609 on major depression differs across MDD subtypes.
The Elongator Subcomplex Elp456 is a Hexameric Reca-Like ATPase.
The elp2 subunit is essential for elongator complex assembly and functional regulation
The epitranscriptome m6A writer METTL3 promotes chemo- and radioresistance in pancreatic cancer cells.
The Era GTPase recognizes the GAUCACCUCC sequence and binds helix 45 near the 3' end of 16S rRNA.
The Escherichia coli FtsH protein is a prokaryotic member of a protein family of putative ATPases involved in membrane functions, cell cycle control, and gene expression.
The Escherichia coli RlmN methyltransferase is a dual-specificity enzyme that modifies both rRNA and tRNA and controls translational accuracy.
The Escherichia coli trmE (mnmE) gene, involved in tRNA modification, codes for an evolutionarily conserved GTPase with unusual biochemical properties.
The Escherichia coli YadB gene product reveals a novel aminoacyl-tRNA synthetase like activity.
The Escherichia coli YadB gene product reveals a novel aminoacyl-tRNA synthetase like activity.
The essential Gcd10p-Gcd14p nuclear complex is required for 1-methyladenosine modification and maturation of initiator methionyl-tRNA.
The essential interaction between yeast mRNA capping enzyme subunits is not required for triphosphatase function in vivo.
The expansion of Inosine at the wobble position of tRNAs, and its role in the evolution of proteomes
The First Structure of an RNA m5C Methyltransferase, Fmu, Provides Insight into Catalytic Mechanism and Specific Binding of RNA Substrate
The first structure of an RNA m5C methyltransferase, Fmu, provides insight into catalytic mechanism and specific binding of RNA substrate.
The flavoprotein Mcap0476 (RlmFO) catalyzes m5U1939 modification in Mycoplasma capricolum 23S rRNA.
The FtsJ/RrmJ heat shock protein of Escherichia coli is a 23 S ribosomal RNA methyltransferase.
The Gcd10p/Gcd14p complex is the essential two-subunit tRNA(1-methyladenosine) methyltransferase of Saccharomyces cerevisiae.
The GTPase activity and C-terminal cysteine of the Escherichia coli MnmE protein are essential for its tRNA modifying function.
The H/ACA RNP assembly factor SHQ1 functions as an RNA mimic.
The Handling of the Mechanistic Probe 5-Fluorouridine by the Pseudouridine Synthase TruA and Its Consistency with the Handling of the Same Probe by the Pseudouridine Synthases TruB and RluA.
The highly conserved KEOPS/EKC complex is essential for a universal tRNA modification, t6A.
The human 18S rRNA base methyltransferases DIMT1L and WBSCR22-TRMT112 but not rRNA modification are required for ribosome biogenesis.
The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112.
The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112.
The human EKC/KEOPS complex is recruited to Cullin2 ubiquitin ligases by the human tumour antigen PRAME.
The human interferon-regulated ISG95 protein interacts with RNA polymerase II and shows methyltransferase activity.
The human methyltransferase ZCCHC4 catalyses N6-methyladenosine modification of 28S ribosomal RNA.
The human mitochondrial 12S rRNA mC methyltransferase METTL15 is required for mitochondrial function.
The human ortholog of archaeal Pus10 produces pseudouridine 54 in select tRNAs where its recognition sequence contains a modified residue.
The Human tRNA m ( 5) C methyltransferase Misu is multisite-specific.
The human tRNA(m(2)(2)G(26))dimethyltransferase: functional expression and characterization of a cloned hTRM1 gene.
The identification of the tRNA substrates for the supK tRNA methylase.
The immunophilin-interacting protein AtFIP37 from Arabidopsis is essential for plant development and is involved in trichome endoreduplication
The isolation and characterization of N-[9-(beta-D-ribofuranosyl)-purin-6-ylcarbamoyl]glycine from yeast transfer RNA.
The K-loop, a general feature of the Pyrococcus C/D guide RNAs, is an RNA structural motif related to the K-turn.
The last rRNA methyltransferase of E. coli revealed: the yhiR gene encodes adenine-N6 methyltransferase specific for modification of A2030 of 23S ribosomal RNA.
The m(6)A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells.
The m1A58 modification in eubacterial tRNA: An overview of tRNA recognition and mechanism of catalysis by Trm
The m6A demethylase FTO promotes the growth of lung cancer cells by regulating them6A level of USP7 mRNA.
The m6A methyltransferase METTL3 promotes osteosarcoma progression by regulating them6A level of LEF1.
The M6A methyltransferase METTL3: acting as a tumor suppressor in renal cell carcinoma.
The mA eraser FTO facilitates proliferation and migration of human cervical cancer cells.
The mA methyltransferase METTL3 promotes bladder cancer progression via AFF4/NF-κB/MYC signaling network.
The mA-suppressed P2RX6 activation promotes renal cancer cells migration and invasion through ATP-induced Ca influx modulating ERK1/2 phosphorylation and MMP9 signaling pathway.
The methyl group of the N6-methyl-N6-threonylcarbamoyladenosine in tRNA of Escherichia coli modestly improves the efficiency of the tRNA.
The methylthiolation reaction mediated by the Radical-SAM enzymes.
The methyltransferase adaptor protein Trm112 is involved in biogenesis of both ribosomal subunits.
The methyltransferase YfgB/RlmN is responsible for modification of adenosine 2503 in 23S rRNA.
The METTL5-TRMT112 N6-methyladenosine methyltransferase complex regulates mRNA translation via 18S rRNA methylation
The modified wobble nucleoside uridine-5-oxyacetic acid in tRNAPro(cmo5UGG) promotes reading of all four proline codons in vivo.
The ms2io6A37 modification of tRNA in Salmonella typhimurium regulates growth on citric acid cycle intermediates.
The N-methyladenosine (mA)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells.
The NADH diphosphatase encoded by the Saccharomyces cerevisiae NPY1 nudix hydrolase gene is located in peroxisomes.
The Neurofibromatosis Type I Messenger RNA Undergoes Base-Modification RNA Editing
The nucleotide sequence of a threonine transfer ribonucleic acid from Escherichia coli.
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.
The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.
The O-Carbamoyltransferase TobZ Catalyzes an Ancient Enzymatic Reaction.
The obesity related gene, FTO, interacts with APOE, and is associated withAlzheimer's disease risk: a prospective cohort study.
The open reading frame TTC1157 of Thermus thermophilus HB27 encodes the methyltransferase forming N(2)-methylguanosine at position 6 in tRNA.
The output of the tRNA modification pathways controlled by the Escherichia coli MnmEG and MnmC enzymes depends on the growth conditions and the tRNA species.
The p27 catalytic subunit of the apolipoprotein B mRNA editing enzyme is a cytidine deaminase
The presence of modified nucleotides is required for cloverleaf folding of a human mitochondrial tRNA.
The presence of N-[9-(beta-D-ribofuranosyl)purin-6-ylcarbamoyl]threonine in serine, methionine and lysine transfer RNA's from Escherichia coli.
The protective effect of the obesity-associated rs9939609 A variant in fat mass- and obesity-associated gene on depression.
The protective effect of the obesity-associated rs9939609 A variant in fat mass- and obesity-associated gene on depression.
The pseudouridine synthase RluD is required for normal ribosome assembly and function in Escherichia coli.
The Pseudouridine Synthase RPUSD4 Is an Essential Component of Mitochondrial RNA Granules.
The ribosomal components responsible for kasugamycin dependence, and its suppression, in a mutant of Escherichia coli.
The ribosomal RNA m5C methyltransferase NSUN-1 modulates healthspan and oogenesis in Caenorhabditis elegans
The ribosome assembly factor Nep1 responsible for Bowen-Conradi syndrome is a pseudouridine-N1-specific methyltransferase
The ribosome assembly factor Nep1 responsible for Bowen-Conradi syndrome is a pseudouridine-N1-specific methyltransferase.
The rlmB gene is essential for formation of Gm2251 in 23S rRNA but not for ribosome maturation in Escherichia coli.
The rluC gene of Escherichia coli codes for a pseudouridine synthase that is solely responsible for synthesis of pseudouridine at positions 955, 2504, and 2580 in 23 S ribosomal RNA.
The RNA acetyltransferase driven by ATP hydrolysis synthesizes N4-acetylcytidine of tRNA anticodon.
The RNA editing enzyme APOBEC1 induces somatic mutations and a compatible mutational signature is present in esophageal adenocarcinomas
The RNA methyltransferase NSUN6 suppresses pancreatic cancer development by regulating cell proliferation.
The RNA Modification Database: 1999 update.
The role of the cysteine residues of ThiI in the generation of 4-thiouridine in tRNA.
The rRNA mA methyltransferase METTL5 is involved in pluripotency and developmental programs.
The Saccharomyces cerevisiae Pus2 protein encoded by YGL063w ORF is a mitochondrial tRNA:Psi27/28-synthase.
The Saccharomyces cerevisiae TAN1 gene is required for N4-acetylcytidine formation in tRNA.
The Saccharomyces cerevisiae U2 snRNA:pseudouridine-synthase Pus7p is a novel multisite-multisubstrate RNA:Psi-synthase also acting on tRNAs.
The scavenger mRNA decapping enzyme DcpS is a member of the HIT family of pyrophosphatases.
The small nucleolar RNP protein NOP1 (fibrillarin) is required for pre-rRNA processing in yeast.
The Solution Structure and DNA-Binding Properties of the Cold-Shock Domain of the Human Y-Box Protein Yb-1.
The solution structure of the Zalpha domain of the human RNA editing enzyme ADAR1 reveals a prepositioned binding surface for Z-DNA.
The specificities of four yeast dihydrouridine synthases for cytoplasmic tRNAs.
The spoU gene of Escherichia coli, the fourth gene of the spoT operon, is essential for tRNA (Gm18) 2'-O-methyltransferase activity.
The ssDNA Mutator APOBEC3A Is Regulated by Cooperative Dimerization.
The structural basis for specific decoding of AUA by isoleucine tRNA on the ribosome.
The structural basis for tRNA recognition and pseudouridine formation by pseudouridine synthase I.
The Structural Basis of Edc3- and Scd6-Mediated Activation of the Dcp1:Dcp2 Mrna Decapping Complex
The structural gene (trmD) for the tRNA(m1G)methyltransferase is part of a four polypeptide operon in Escherichia coli K-12.
The structure of APOBEC1 and insights into its RNA and DNA substrate selectivity.
The Structure of Escherichia coli TcdA (Also Known As CsdL) Reveals a Novel Topology and Provides Insight into the tRNA Binding Surface Required for N(6)-Threonylcarbamoyladenosine Dehydratase Activity.
The Structure of Escherichia coli TcdA (Also Known As CsdL) Reveals a Novel Topology and Provides Insight into the tRNA Binding Surface Required for N-Threonylcarbamoyladenosine Dehydratase Activity.
The Structure of the Box C/D Enzyme Reveals Regulation of RNA Methylation.
The structure of the hypothetical protein smu.1377c from Streptococcus mutans suggests a role in tRNA modification.
The Structure of the Rlmb 23S Rrna Methyltransferase Reveals a New Methyltransferase Fold with a Unique Knot
The structure of the RlmB 23S rRNA methyltransferase reveals a new methyltransferase fold with a unique knot.
The structure of the RNA m5C methyltransferase YebU from Escherichia coli reveals a C-terminal RNA-recruiting PUA domain
The structure of the RNA m5C methyltransferase YebU from Escherichia coli reveals a C-terminal RNA-recruiting PUA domain.
The structure of the TrmE GTP-binding protein and its implications for tRNA modification
The structure of the TrmE GTP-binding protein and its implications for tRNA modification.
The structure of the TsaB/TsaD/TsaE complex reveals an unexpected mechanism for the bacterial t6A tRNA-modification.
The structure of the yrdC gene product from Escherichia coli reveals a new fold and suggests a role in RNA binding.
The structure of the yrdC gene product from Escherichia coli reveals a new fold and suggests a role in RNA binding.
The structures of non-CG-repeat Z-DNAs co-crystallized with the Z-DNA-binding domain, hZ{alpha}ADAR1
The structures of non-CG-repeat Z-DNAs co-crystallized with the Z-DNA-binding domain, hZ{alpha}ADAR1
The study of METTL3 and METTL14 expressions in childhood ETV6/RUNX1-positive acute lymphoblastic leukemia.
The Sua5 protein is essential for normal translational regulation in yeast.
The sulfurtransferase activity of Uba4 presents a link between ubiquitin-like protein conjugation and activation of sulfur carrier proteins
The synthesis of 2'-O-[(Triisopropylsilyl)oxy] methyl (TOM) phosphoramidites of methylated ribonucleosides (m1G, m2G, m22G, m1I, m3U, m4C, m6A, m62A) for use in automated RNA solid-phase synthesis
The Synthesis of Allyl- and Ailyioxycarbonyl-Protected RNA Phosphoramidites. Useful Reagents for Solid-Phase Synthesis of RNAs with Base-Labile Modifications
The synthesis of oligoribonucleotides containing N6-alkyladenosines and 2-methylthio-N6-alkyladenosines via post-synthetic modification of precursor oligomers.
The Treacher Collins syndrome (TCOF1) gene product is involved in pre-rRNAmethylation.
The tRNA methyltransferase NSun2 stabilizes p16INK⁴ mRNA by methylating the 3'-untranslated region of p16.
The tRNA recognition mechanism of folate/FAD-dependent tRNA methyltransferase (TrmFO).
The tRNA recognition mechanism of the minimalist SPOUT methyltransferase, TrmL
The tRNA recognition mechanism of the minimalist SPOUT methyltransferase, TrmL
The tRNA recognition mechanism of the minimalist SPOUT methyltransferase, TrmL.
The tylosin-resistance methyltransferase RlmA(II) (TlrB) modifies the N-1 position of 23S rRNA nucleotide G748.
The U6 snRNA m6A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention
The universal Kae1 protein and the associated Bud32 kinase (PRPK), a mysterious protein couple probably essential for genome maintenance in Archaea and Eukarya.
The universal YrdC/Sua5 family is required for the formation of threonylcarbamoyladenosine in tRNA.
The use of labilebaseprotectinggroups in oligoribonucleotidesynthesis
The wobble hypothesis revisited: uridine-5-oxyacetic acid is critical for reading of G-ending codons.
The ybiN gene of Escherichia coli encodes adenine-N6 methyltransferase specific for modification of A1618 of 23 S ribosomal RNA, a methylated residue located close to the ribosomal exit tunnel.
The yeast gene YNL292w encodes a pseudouridine synthase (Pus4) catalyzing the formation of psi55 in both mitochondrial and cytoplasmic tRNAs.
The yeast ribosome synthesis factor Emg1 is a novel member of the superfamily of alpha/beta knot fold methyltransferases.
The Yeast Ribosome Synthesis Factor Emg1 is a Novel Member of the Superfamily of Alpha/Beta Knot Fold Methyltransferases.
The yeast Saccharomyces cerevisiae YDL112w ORF encodes the putative 2'-O-ribose methyltransferase catalyzing the formation of Gm18 in tRNAs.
The yeast tRNA:pseudouridine synthase Pus1p displays a multisite substrate specificity.
The yfhQ gene of Escherichia coli encodes a tRNA:Cm32/Um32 methyltransferase.
The yfiC gene of E. coli encodes an adenine-N6 methyltransferase that specifically modifies A37 of tRNA1Val(cmo5UAC).
The yggH gene of Escherichia coli encodes a tRNA (m7G46) methyltransferase.
The YqfN protein of Bacillus subtilis is the tRNA: m1A22 methyltransferase (TrmK).
Thio-modification of yeast cytosolic tRNA requires a ubiquitin-related system that resembles bacterial sulfur transfer systems.
Thiobases in Escherchia coli Transfer RNA: 2-Thiocytosine and 5-Methylaminomethyl-2-thiouracil.
Three distinct 3-methylcytidine (m(3)C) methyltransferases modify tRNA and mRNA in mice and humans.
THUMP from archaeal tRNA:m22G10 methyltransferase, a genuine autonomously folding domain.
THUMP--a predicted RNA-binding domain shared by 4-thiouridine, pseudouridine synthases and RNA methylases.
THUMPD3-TRMT112 is a m2G methyltransferase working on a broad range of tRNA substrates.
Topological Characterization of Human and Mouse mC Epitranscriptome Revealed by Bisulfite Sequencing.
TRAM, a predicted RNA-binding domain, common to tRNA uracil methylation and adenine thiolation enzymes.
Transcriptome-wide map of mA circRNAs identified in a rat model of hypoxia mediated pulmonary hypertension.
Transfer and isomerization of the ribose moiety of AdoMet during the biosynthesis of queuosine tRNAs, a new unique reaction catalyzed by the QueA protein from Escherichia coli.
Transfer RNA demethylase ALKBH3 promotes cancer progression via induction oftRNA-derived small RNAs.
Transfer RNA modification enzymes from Pyrococcus furiosus: detection of the enzymatic activities in vitro.
Transfer RNA recognition by the Escherichia coli delta2-isopentenyl-pyrophosphate:tRNA delta2-isopentenyl transferase: dependence on the anticodon arm structure.
Transfer RNA(5-methylaminomethyl-2-thiouridine)-methyltransferase from Escherichia coli K-12 has two enzymatic activities.
Transfer RNA-pseudouridine synthetase Pus1 of Saccharomyces cerevisiae contains one atom of zinc essential for its native conformation and tRNA recognition.
Translational adaptation to heat stress is mediated by RNA 5-methylcytosine in Caenorhabditis elegans
Translational defects of Escherichia coli mutants deficient in the Um(2552) 23S ribosomal RNA methyltransferase RrmJ/FTSJ.
Translational infidelity-induced protein stress results from a deficiency in Trm9-catalyzed tRNA modifications.
Translational misreading: a tRNA modification counteracts a +2 ribosomal frameshift.
Trm112 Is Required for Bud23-Mediated Methylation of the 18S rRNA at Position G1575.
Trm112p is a 15-kDa zinc finger protein essential for the activity of two tRNA and one protein methyltransferases in yeast.
Trm11p and Trm112p are both required for the formation of 2-methylguanosine at position 10 in yeast tRNA.
Trm13p, the tRNA:Xm4 modification enzyme from Saccharomyces cerevisiae is a member of the Rossmann-fold MTase superfamily: prediction of structure and active site.
Trm4 and Nsun2 RNA:mC Methyltransferases Form Metabolite-Dependent, Covalent Adducts with Previously Methylated RNA.
TRM6/61 connects PKCα with translational control through tRNAi(Met) stabilization: impact on tumorigenesis.
Trm7p catalyses the formation of two 2'-O-methylriboses in yeast tRNA anticodon loop.
Trm9-Catalyzed tRNA Modifications Regulate Global Protein Expression by Codon-Biased Translation
TRMT1-Catalyzed tRNA Modifications Are Required for Redox Homeostasis To Ensure Proper Cellular Proliferation and Oxidative Stress Survival
TRMT10A dysfunction is associated with abnormalities in glucose homeostasis, short stature and microcephaly.
TRMT2B is responsible for both tRNA and rRNA mU-methylation in human mitochondria.
Trmt61B is a methyltransferase responsible for 1-methyladenosine at position 58 of human mitochondrial tRNAs.
tRNA binding, positioning and modification by the pseudouridine synthase Pus10.
tRNA m7G methyltransferase Trm8p/Trm82p: evidence linking activity to a growth phenotype and implicating Trm82p in maintaining levels of active Trm8p.
tRNA N6-adenosine threonylcarbamoyltransferase defect due to KAE1/TCS3 (OSGEP) mutation manifest by neurodegeneration and renal tubulopathy.
tRNA recognition by a bacterial tRNA Xm32 modification enzyme from the SPOUT methyltransferase superfamily.
tRNA transfers to the limelight.
tRNA-modifying MiaE protein from Salmonella typhimurium is a nonheme diiron monooxygenase.
tRNAGlu wobble uridine methylation by Trm9 identifies Elongator's key role for zymocin-induced cell death in yeast.
tRNAHis guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'-3' DNA polymerases.
tRNAHis guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'-3' DNA polymerases.
tRNAHis guanylyltransferase (THG1), a unique 3′-5′ nucleotidyl transferase, shares unexpected structural homology with canonical 5′-3′ DNA polymerases.
tRNAHis maturation: an essential yeast protein catalyzes addition of a guanine nucleotide to the 5' end of tRNAHis.
TRUB1 is the predominant pseudouridine synthase acting on mammalian mRNA via a predictable and conserved code.
TtcA a new tRNA-thioltransferase with an Fe-S cluster.
Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance.
Two different kinds of interaction modes of deaminase APOBEC3A with single-stranded DNA in solution detected by nuclear magnetic resonance.
Two proteins that form a complex are required for 7-methylguanosine modification of yeast tRNA.
U2 snRNA is inducibly pseudouridylated at novel sites by Pus7p and snR81 RNP.
Ubiquitin-related modifier Urm1 acts as a sulphur carrier in thiolation of eukaryotic transfer RNA.
Ultrafast Cleavage and Deprotection of Oligonucleotides Synthesis and Use of CAc Derivatives
Underediting of glutamate receptor GluR-B mRNA in malignant gliomas.
Understanding the Structure, Multimerization, Subcellular Localization and mC Selectivity of a Genomic Mutator and Anti-HIV Factor APOBEC3H.
Unexpected accumulation of ncm(5)U and ncm(5)S(2) (U) in a trm9 mutant suggests an additional step in the synthesis of mcm(5)U and mcm(5)S(2)U.
Unexpected expansion of tRNA substrate recognition by the yeast m1G9 methyltransferase Trm10.
Unique Features of the m6A Methylome in Arabidopsis thaliana
Unique structural and stabilizing roles for the individual pseudouridine residues in the 1920 region of Escherichia coli 23S rRNA.
Unveiling structural and functional divergences of bacterial tRNA dihydrouridine synthases: perspectives on the evolution scenario.
Upregulated METTL3 promotes metastasis of colorectal Cancer via miR-1246/SPRED2/MAPK signaling pathway.
Uridin-5-oxy acetic acid: a new minor constituent from E. coli valine transfer RNA I.
Variants in PUS7 Cause Intellectual Disability with Speech Delay, Microcephaly,Short Stature, and Aggressive Behavior.
Variants in SUP45 and TRM10 underlie natural variation in translation termination efficiency in Saccharomyces cerevisiae.
Vip1 is a kinase and pyrophosphatase switch that regulates inositol diphosphate signaling.
Vip1 is a kinase and pyrophosphatase switch that regulates inositol diphosphate signaling.
Visualizing formation of the active site in the mitochondrial ribosome.
Visualizing late states of human 40S ribosomal subunit maturation.
Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.
Whole exome sequencing identifies a splicing mutation in NSUN2 as a cause of a Dubowitz-like syndrome.
Widespread occurrence of 5-methylcytosine in human coding and non-coding RNA.
Wilms' tumor 1-associating protein promotes renal cell carcinoma proliferation by regulating CDK2 mRNA stability.
Wilms' tumour 1-associating protein inhibits endothelial cell angiogenesis by m6A-dependent epigenetic silencing of desmoplakin in brain arteriovenous malformation.
Wobble modification deficiency in mutant tRNAs in patients with mitochondrial diseases.
WTAP Expression Predicts Poor Prognosis in Malignant Glioma Patients.
WTAP Expression Predicts Poor Prognosis in Malignant Glioma Patients.
WTAP facilitates progression of hepatocellular carcinoma via m6A-HuR-dependent epigenetic silencing of ETS1.
X-ray crystal structure of a hypothetical Sua5 protein from Sulfolobus tokodaii strain 7.
X-ray structure of tRNA pseudouridine synthase TruD reveals an inserted domain with a novel fold
X-ray structure of tRNA pseudouridine synthase TruD reveals an inserted domain with a novel fold.
X-ray structures of U2 snRNA-branchpoint duplexes containing conserved pseudouridines.
YbeA is the m3Psi methyltransferase RlmH that targets nucleotide 1915 in 23S rRNA.
YccW is the m5C methyltransferase specific for 23S rRNA nucleotide 1962.
Yeast 18S rRNA dimethylase Dim1p: a quality control mechanism in ribosome synthesis?
Yeast Kre33 and human NAT10 are conserved 18S rRNA cytosine acetyltransferases that modify tRNAs assisted by the adaptor Tan1/THUMPD1.
Yeast mitochondrial initiator tRNA is methylated at guanosine 37 by the Trm5-encoded tRNA (guanine-N1-)-methyltransferase.
Yeast mRNA cap methyltransferase is a 50-kilodalton protein encoded by an essential gene.
Yeast Nfs1p is involved in thio-modification of both mitochondrial and cytoplasmic tRNAs.
Yeast Nop2 and Rcm1 methylate C2870 and C2278 of the 25S rRNA, respectively
Yeast Nop2 and Rcm1 methylate C2870 and C2278 of the 25S rRNA, respectively.
Yeast NOP2 encodes an essential nucleolar protein with homology to a human proliferation marker.
Yeast Rrp8p, a novel methyltransferase responsible for m1A 645 base modification of 25S rRNA.
Yeast serine isoacceptor tRNAs: variations of their content as a function of growth conditions and primary structure of the minor tRNA(Ser)GCU.
Yeast targets for mRNA methylation.
Yeast Trm7 interacts with distinct proteins for critical modifications of the tRNAPhe anticodon loop.
YebU is a m5C methyltransferase specific for 16 S rRNA nucleotide 1407.
YgdE is the 2'-O-ribose methyltransferase RlmM specific for nucleotide C2498 in bacterial 23S rRNA.
YhiQ Is RsmJ, the Methyltransferase Responsible for Methylation of G1516 in 16S rRNA of E. coli.
YibK is the 2'-O-methyltransferase TrmL that modifies the wobble nucleotide in Escherichia coli tRNA(Leu) isoacceptors.
YrdC exhibits properties expected of a subunit for a tRNA threonylcarbamoyl transferase.
YTH domain family 2 orchestrates epithelial-mesenchymal transition/proliferation dichotomy in pancreatic cancer cells.
YTH domain family 2 promotes lung cancer cell growth by facilitating6-phosphogluconate dehydrogenase mRNA translation.
YTHDF1 Regulates Tumorigenicity and Cancer Stem Cell-Like Activity in Human Colorectal Carcinoma
YTHDF1 Regulates Tumorigenicity and Cancer Stem Cell-Like Activity in Human Colorectal Carcinoma.
YTHDF2 reduction fuels inflammation and vascular abnormalization in hepatocellular carcinoma.
YTHDF2 suppresses cell proliferation and growth via destabilizing the EGFR mRNA inhepatocellular carcinoma.
Zipper head mechanism of telomere synthesis by human telomerase.

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