Traditional Name Full name Synonym GI Orf COG UniProt Structures (PDB id)

Position

Modification
type

Complex Enzyme Type Organism
15.5kD Ribosomal protein L7Ae 159111753 GL50803_11287 COG1358 A8BMJ0 3O85
C/D RNP Giardia lamblia
ABH1 Nucleic acid dioxygenase ALKBH1 ALKBH1 87298839
Homo sapiens
ADAT2 adenosine deaminase, tRNA specific 2 dJ20N2.1, TAD2 None Q7Z6V5
deaminase Homo sapiens
ADAT3 adenosine deaminase, tRNA specific 3 TAD3 None Q96EY9
deaminase Homo sapiens
ALKBH5 ABH5, OFOXD1 148539642 Q6P6C2 4NJ4, 4NRM, 4NRO, 4NRP, 4NRQ, 4O7X, 4OCT, 4O61
m:many A
demethylase Homo sapiens
ALKBH8 Alkylated DNA repair protein alkB homolog 8 ABH8 189027650 COG3145 Q96BT7 3THT, 3THP
t:34 mchm5U
t:34 mcm5s2U
t:34 mcm5U
t:34 mcm5Um
ALKBH8/TRM112 methyltransferase, hydroxylase Homo sapiens
Abd1 RNA cap guanine-N7 methyltransferase MceS 416567 YBR1602 COG2226 P32783
m:0 m7Gpp(pN)
methyltransferase Saccharomyces cerevisiae
ArcS glutamine:preQ0-tRNA amidinotransferase or Archaeosine Synthase Archaeosine synthase, Glutamine:preQ0-tRNA amidinotransferase 3024970 COG1549 Q58428
t:15 G+
amidinotransferase Methanocaldococcus jannaschii
ArcTGT Archaeosine tRNA-guanine transglycosylase None
t:13 G+
t:15 G+
transglycosylase Thermoplasma acidophilum
ArmA rRNA adenine N-7-methyltransferase aminoglycoside resistance 16S rRNA methyltransferase 124021052 armA COG2813 Q6F5A0 3FZG
s:1405(1405) m7G
methyltransferase Escherichia coli
AviRa rRNA guanine N-1-methyltransferase avilamycin resistance 23S rRNA methyltransferase 28380397 aviRa COG1041 Q9F5K5 1O9G, 1O9H
l:2535(2535) m1G
methyltransferase Streptomyces viridochromogenes
AviRb rRNA (uridine-2'-O-)-methyltransferase avilamycin resistance 23S rRNA methyltransferase 60593969 aviRb COG0566 Q9F5K6 1X7O, 1X7P
l:2479(2479) Um
methyltransferase Streptomyces viridochromogenes
BCDIN3 RNA cap gamma-methyltransferase 7SK snRNA methylphosphate capping enzyme (MePCE), Bicoid-interacting protein 3 homolog 74758999 MEPCE COG2264 Q7L2J0
n:0 m7Gpp(pN)
methyltransferase Homo sapiens
BCDIN3D BCDIN3 domain containing 32171233 Q7Z5W3
pre-miRNA:0 mm(pN)
methyltransferase Homo sapiens
Bmt2 YBR141C 330443457 YBR1118 P38278
l:2142(1784) m1A
methyltransferase Saccharomyces cerevisiae
Bmt5 6322095 YIL096C P40493
l:2634(2265) m3U
methyltransferase Saccharomyces cerevisiae
Bmt6 YLR063W 6323092 L2174 Q12291
l:2843(2474) m3U
methyltransferase Saccharomyces cerevisiae
Bud23 Bud23 140499 YCR47C COG2230 P25627
s:1575(1338) m7G
methyltransferase Saccharomyces cerevisiae
Bud32 Serine/threonine-protein kinase BUD32 PRPK, LDB14, YGR262c 6321701 COG3642 P53323
t:37 t6A
EKC/KEOPS kinase Saccharomyces cerevisiae
CDAT8 tRNA-specific cytidine deaminase MK0935 238537840 COG2131 Q8TWU6 3G8Q
t:8 U
deaminase Methanopyrus kandleri
CDKAL1 CDK5 regulatory subunit associated protein 1 like 1 FLJ20342 None Q5VV42
threonylcarbamoyladenosine synthetase Homo sapiens
CMTr1 cap methyltranferase 1 hMTr1, FTSJD2, KIAA0082 74750894 FTSJD2, KIAA0082 COG0293 Q8N1G2
n:1 m7GpppNm
m:1 m7GpppNm
methyltransferase Homo sapiens
CMTr2 cap methyltranferase 2 hMTr2, FTSJD1, FLJ11171 269849596 FTSJD1, FLJ11171 COG0293 Q8IYT2
n:2 m7GpppNmNm
m:2 m7GpppNmNm
methyltransferase Homo sapiens
CTU1 cytosolic thiouridylase subunit 1 MGC17332, NCS6 None Q7Z7A3
thiolase Homo sapiens
Cbf5 H/ACA ribonucleoprotein complex subunit 4 dyskerine 461698 YLR175W COG0130 P33322 3UAI, 3U28
t:many Y
s:many Y
l:many Y
n:many Y
H/ACA RNP pseudouridine synthase Saccharomyces cerevisiae
Cbf5 PF1785 18978157 COG0130 Q7LWY0 3HJW, 3HJY
l:many Y
n:many Y
t:many Y
s:many Y
H/ACA RNP pseudouridine synthase Pyrococcus furiosus
Ceg1 GTP-RNA guanylyltransferase GTase, Mce1 1322697 CEG1 COG5226 Q01159 3KYH
m:0 m7Gpp(pN)
guanylyltransferase Saccharomyces cerevisiae
Cet1 RNA triphosphatase Cet1 Polynucleotide 5'-triphosphatase, mRNA 5'-triphosphatase, Tpase 308153424 P1433 COG4943 O13297 1D8HA, 1D8HB, 1D8HC, 1D8IA, 1D8IB, 1D8IC
m:0 m7Gpp(pN)
triphosphatase/hydrolase Saccharomyces cerevisiae
Cfr Ribosomal RNA large subunit methyltransferase Cfr pSCFS1 75466541 COG0820 Q9FBG4
l:2503(2503) m2,8A
l:2503(2503) m8A
methyltransferase Staphylococcus sciuri
Cgi121 MJ0187 15668359 COG1617 Q57646 2K8Y, 3ENH
t:37 t6A
EKC/KEOPS pseudouridine synthase Methanocaldococcus jannaschii
Cgi121 YML036w 154199620 COG1617 Q03705
t:37 t6A
EKC/KEOPS pseudouridine synthase Saccharomyces cerevisiae
CmoA tRNA (uridine-5-oxyacetic acid methyl ester)(34) synthase YecO 3025151 b1870 COG2226 P76290 4GEK, 4IWN
t:34 cmo5U
t:34 mcmo5U
methyltransferase Escherichia coli
CmoA tRNA (cmo5U34)-methyltransferase YecO 16272273 COG2226 P43985 1IM8
t:34 cmo5U
methyltransferase Haemophilus influenzae
CmoB tRNA 5-methoxyuridine(34) synthase YecP 3025152 b1871 COG2230 P76291 4QNX,4QNU,4QNV
t:34 cmo5U
t:34 mcmo5U
carboxymethyltransferase Escherichia coli
DIMT1L dimethyladenosine transferase DIMT1 1143076922
s:1850(1518) m6,6A
s:1851(1519) m6,6A
methyltransferase Homo sapiens
DR_0049 DR_0049 None
methyltransferase Deinococcus radiodurans
Dcp2 RNA decapping complex subunit 2 74675930 dcp2 COG0494 O13828 2A6T
hydrolase Schizosaccharomyces pombe
DcpS Scavenger mRNA-decapping enzyme DcpS DCS-1, Hint-related 7meGMP-directed hydrolase, HINT5 116241325 HSPC015 COG5075 Q96C86 1ST0, 1ST4, 1XML, 1XMM
hydrolase Homo sapiens
DnmA DNA (cytosine-5)-methyltransferase DNA -methyltransferase None Q54JH6
t:38 m5C
methyltransferase Dictyostelium discoideum
Dnmt2 tRNA (cytosine(38)-C(5))-methyltransferase 4758184 TRDMT1 COG0270 O14717 1G55
t:38 m5C
methyltransferase Homo sapiens
Dnmt2 tRNA (cytosine(38)-C(5))-methyltransferase GSU0227 39995337 Q74GL9
t:38 m5C
methyltransferase Geobacter sulfurreducens
Dus1 tRNA-dihydrouridine synthase 1 1730621 YML080W COG0042 P53759
t:16 D
t:17 D
dihydrouridine synthase Saccharomyces cerevisiae
Dus2 tRNA-dihydrouridine synthase 2 Smm1p 1730664 YNR015W COG0042 P53720
t:20 D
dihydrouridine synthase Saccharomyces cerevisiae
Dus2 tRNA-dihydrouridine(20) synthase [NAD(P)+]-like DUS2L 8923374 COG0042 Q9NX74 4WFS,4WFT
dihydrouridine synthase Homo sapiens
Dus3 tRNA-dihydrouridine synthase 3 547573 YLR401C Q06053
t:47 D
dihydrouridine synthase Saccharomyces cerevisiae
Dus4 tRNA-dihydrouridine synthase 4 2833204 YLR405W, L8084.2 COG0042 Q06063
t:20a D
t:20b D
dihydrouridine synthase Saccharomyces cerevisiae
DusA tRNA dihydrouridine synthase A YjbN 3183570 yjbN, b4049 COG0042 P32695
t:20 D
dihydrouridine synthase Escherichia coli
DusB tRNA dihydrouridine synthase B YhdG 78100051 yhdG,b3260 COG0042 P0ABT5
t:16 D
t:20a D
t:20 D
t:17 D
dihydrouridine synthase Escherichia coli
DusC tRNA dihydrouridine synthase C YohI 466094 yohI, b2140 COG0042 P33371 3w9z
t:20 D
t:20a D
t:17 D
t:16 D
dihydrouridine synthase Escherichia coli
ELP1 Elongator complex protein 1 IKAP, TOT1, IKI3 None O95163
Homo sapiens
ELP3 elongator acetyltransferase complex subunit 3 FLJ10422 KAT9 None Q9H9T3
acetyltransferase Homo sapiens
EfmM rRNA cytydine C-5-methyltransferase kanamycin and tobramycin resistance 16S rRNA methyltransferase 383329552 efmM E9KIK3 3M4X
s:1404(1404) m5C
methyltransferase Enterococcus faecium
Elp1 Elongator complex protein 1 IKI3, TOT1 2498477 L3502.7 COG5290 Q06706
Elongator complex Saccharomyces cerevisiae
Elp2 Elongator complex protein 2 TOT2 1176045 G7725 COG2319 P42935
Elongator complex Saccharomyces cerevisiae
Elp3 Elongator complex protein 3 HPA1, TOT3 6325171 COG1243 Q02908
Elongator complex Saccharomyces cerevisiae
Elp4 Elongator complex protein 4 HAP1, TOT7 6325155 COG0467 Q02884
Elongator complex Saccharomyces cerevisiae
Elp5 Elongator complex protein 5 ELP5, HAP2, TOT5, IKI1 377656546 COG1074 P38874
Elongator complex Saccharomyces cerevisiae
Elp6 Elongator complex protein 6 HAP3, TOT6 6323972 YM9924.04 COG1021 Q04868
Elongator complex Saccharomyces cerevisiae
ErmAM rRNA adenine N-6-methyltransferase macrolide-lincosamide-streptogramin B resistance 23S rRNA methyltransferase 127202 ermAM COG0030 P21236 1YUB
l:2085(2085) m6A
methyltransferase Streptococcus pneumoniae
ErmBC rRNA adenine N-6-methyltransferase 127199 COG0030 P10738
l:2058(2058) m6A
methyltransferase Escherichia coli
ErmC' rRNA adenine N-6-methyltransferase macrolide-lincosamide-streptogramin B resistance 23S rRNA methyltransferase 127198 ermC' COG0030 P13956 1QAM, 1QAN, 1QAO, 1QAQ
l:2085(2058) m6A
methyltransferase Bacillus subtilis
FBL rRNA 2′-O-methyltransferase fibrillarin FIB1, FLRN, fibrillarin 12056465 COG1889 P22087 2IPX
l:many Xm
s:many Xm
C/D RNP methyltransferase Homo sapiens
FTO Alpha-ketoglutarate-dependent dioxygenase FTO KIAA1752 122937263 Q9C0B1 3LFM
m:many A
m:many f6A
m:many hm6A
demethylase Homo sapiens
FTSJ1 FtsJ RNA methyltransferase homolog 1 JM23 CDLIV SPB1 TRM7 TRMT7 None Q9UET6
methyltransferase Homo sapiens
FlpA Fibrillarin-like rRNA/tRNA 2′-O-methyltransferase aFib, Fibrillarin-like 15897821 C33_014 COG1889 P58032 3PLA, 3ID5, 3ID6
l:many Xm
s:many Xm
C/D RNP methyltransferase Sulfolobus solfataricus
FlpA Fibrillarin-like rRNA/tRNA 2′-O-methyltransferase aFib, MJ0697, Fibrillarin-like 15668878 COG1889 Q58108 1G8S, 1FBN
l:many Xm
s:many Xm
C/D RNP methyltransferase Methanocaldococcus jannaschii
FlpA Fibrillarin-like rRNA/tRNA 2′-O-methyltransferase aFib, PH0052, Fibrillarin-like 14590005 COG1889 O57811 1G8A
l:many Xm
s:many Xm
C/D RNP methyltransferase Pyrococcus horikoshii
FlpA Fibrillarin-like rRNA/tRNA 2′-O-methyltransferase aFib, Fibrillarin-like, PF0059 18976431 COG1889 Q8U4M2 2NNW, 3NVM
l:many Xm
s:many Xm
C/D RNP methyltransferase Pyrococcus furiosus
FlpA Fibrillarin-like rRNA/tRNA 2′-O-methyltransferase aFib, Fibrillarin-like, AF_2087 11499669 COG1889 O28192 1NT2
l:many Xm
s:many Xm
C/D RNP methyltransferase Archaeoglobus fulgidus
GON7 GON7, KEOPS complex subunit 14q32.12 None Q9BXV9
Homo sapiens
Gar1 H/ACA ribonucleoprotein complex subunit 1 120941 YHR089C COG3277 P28007 3UAI, 3U28
H/ACA RNP Saccharomyces cerevisiae
GluQRS tRNA glutamyl-Q(34) synthetase YadB 85674352 b0144 COG0008 P27305 1NZJ, 4A91
t:34 gluQtRNA
aminoacyl-tRNA synthetase-like Escherichia coli
HCAP1 RNA-capping enzyme HCE, mRNA 5'-triphosphatase, GTP--RNA guanylyltransferase 6685628 RNGTT COG5226 O60942 3S24
m:0 m7Gpp(pN)
triphosphatase, guanylyltransferase Homo sapiens
HSD17B10 3-hydroxyacyl-CoA dehydrogenase type-2 SDR5C1, ERAB, HADH2, MRPP2, SCHAD, XH98G2 2492759 COG1028 Q99714 1SO8, 1U7T, 2O23
mtRNase P Homo sapiens
Hcm1 RNA cap guanine-N7 methyltransferase mRNA cap methyltransferase, RG7MT1, hCMT1, hMet 74735378 RNMT, KIAA0398 COG2226 O43148 3EPP, 3BGV
m:1 m7Gpp(pN)
methyltransferase Homo sapiens
Hen1 Small RNA 2′-O-methyltransferase CORYMBOSA 2, HUA ENHANCER 1 15638615 T13K14.70 COG2227 Q9C5Q8 3HTX
miRNA:3' end Xm
methyltransferase Arabidopsis thaliana
Hen1 Cthe_2767 125975249 COG2227 A3DJ37 3JWI, 3JWG
undefined RNA:3' end Xm
methyltransferase Clostridium thermocellum
ISCU iron-sulfur cluster assembly enzyme ISU2, hnifU, IscU None Q9H1K1
Homo sapiens
Ime4 N6-adenosine-methyltransferase IME4 Mrm(m6A), Spo8 1174426 YGL192W, G1337 COG4725 P41833
m:many m6A
methyltransferase Saccharomyces cerevisiae
IscA Iron-binding protein iscA YfhF 16130453 b2528 COG0316 P0AAC8 1S98
Escherichia coli
IscS Cysteine desulfurase IscS subfamily NuvC 67466100 b2530 COG1104 P0A6B7 1P3W, 3LMV
cysteine desulfurase Escherichia coli
KamB rRNA adenine N-1-methyltransferase aminoglycoside-resistance 16S rRNA methyltransferase 85813531 kamB COG4106 P25920 3MQ2
s:1408(1408) m1A
methyltransferase Streptomyces sp. DSM 40477
Kti11 Diphthamide biosynthesis protein 3 DPH3 21648335 COG5216 Q3E840 1YOP,1YWS,4D4P,4D4O
Saccharomyces cerevisiae
Kti12 Killer toxin insensitivity protein 12 6322739 YKL446, YKL500 COG4088 P34253
Saccharomyces cerevisiae
Kti13 Alpha-tubulin suppressor 1 ATS1 330443378 FUN28, YAL006 COG5184 P31386 4D4Q,4D4O,4D4P
Saccharomyces cerevisiae
Kti14 Casein kinase I homolog HRR25 HRR25 6325052 COG0515 P29295
Saccharomyces cerevisiae
L7Ae 50S ribosomal protein L7Ae rpl7ae, PF1367 18977739 COG1358 Q8U160 3NMU
C/D RNP Pyrococcus furiosus
L7Ae 50S ribosomal protein L7Ae rpl7ae, SSO0091 15897054 C04_031 COG1358 P55858 3ICX, 3ID5, 3ID6
C/D RNP Sulfolobus solfataricus
L7Ae 50S ribosomal protein L7Ae rpl7ae, MJ1203 15669389 COG1358 P54066 1RA4, 1XBI, 1SDS
C/D RNP Methanocaldococcus jannaschii
L7Ae 50S ribosomal protein L7Ae rpl7ae, AF_0764 11498370 COG1358 O29494 1RLG
C/D RNP Archaeoglobus fulgidus
LAGE3 L antigen family member 3 ITBA2 CVG5 DXS9951E DXS9879E ESO3 Pcc1 None Q14657
Homo sapiens
METTL1 tRNA (guanine-N(7)-)-methyltransferase TRMB 167004078 C12orf1 COG0220 Q9UBP6 3CKK
t:46 m7G
TRMB/WDR4 methyltransferase Homo sapiens
METTL14 KIAA1627 24308265 COG4725 Q9HCE5
m:many m6A
METTL3-METTL14 methyltransferase Homo sapiens
METTL2 Methyltransferase-like protein 2A METTL2A 165932357
methyltransferase Homo sapiens
METTL3 N6-adenosine-methyltransferase 70 kDa subunit MTA70 21361827 COG4725 Q86U44
m:many m6A
methyltransferase Homo sapiens
METTL6 methyltransferase like 6 MGC24132 None Q8TCB7
methylthiotransferase Homo sapiens
MOCS3 molybdenum cofactor synthesis 3 UBA4, dJ914P20.3 None O95396
adenylyltransferase, sulfurtransferase Homo sapiens
MRM1 rRNA methyltransferase 1, mitochondrial 40068479 COG0566 Q6IN84
l:1145(2251) Gm
methyltransferase Homo sapiens
MRM2 rRNA methyltransferase 2, mitochondrial FTSJ2, FJH1 7019377 COG0293 Q9UI43 2NYU
l:1369(2552) Um
methyltransferase Homo sapiens
MRM3 rRNA methyltransferase 3, mitochondrial RNMTL1 962608793
l:1370(2553) Gm
methyltransferase Homo sapiens
MTA70 N6-adenosine-methyltransferase MT-A70-like 1063721623
methyltransferase Arabidopsis thaliana
Man/Gal-Q-transferase tRNA-queuine glycosyltransferase None
t:34 galQtRNA
t:34 manQtRNA
hexose transferase various eukaryotes
Mettl16 U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase 102126585
methyltransferase Homo sapiens
MiaA tRNA (adenosine(37)-N6)-dimethylallyltransferase TrpX 127087 b4171 COG0324 P16384 3FOZ, 2ZM5, 2ZXU
t:37 i6A
dimethylallyltransferase Escherichia coli
MiaB tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase YleA 83288203 b0661 COG0621 P0AEI1
t:37 ms2i6A
methylthiotransferase Escherichia coli
MiaE tRNA 2-methylthio-N6-isopentenyl adenosine(37) hydroxylase 312708 STM4471 COG4445 Q08015 2ITB
t:37 ms2io6A
hydroxylase Salmonella typhimurium
MnmA tRNA 2-thiouridine(34) synthase TrmU, AsuE, YcfB 8039808 b1123 COG0482 P25745 2DET, 2DEU, 2DER
t:34 s2U
t:34 mnm5s2U
thiolase Escherichia coli
MnmA tRNA-specific 2-thiouridylase mnmA TrmU 15900060 COG0482 Q97T38 2HMA
t:34 s2U
t:34 mnm5s2U
thiolase Streptococcus pneumoniae
MnmCD tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase / FAD-dependent cmnm(5)s(2)U34 oxidoreductase TrmC, MnmC 20140544 yfcK, b2324 COG4121 P77182 3AWI, 3PS9
t:34 mnm5s2U
t:34 mnm5U
methyltransferase/oxidoreductase Escherichia coli
MnmCD tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmCD 218929828 COG4121 Q8ZD36 3PVC, 3SGL
t:34 mnm5s2U
t:34 mnm5U
methyltransferase/oxidoreductase Yersinia pestis
MnmD MnmD tRNA methyltransferase MnmC2 15606976 aq_1980 COG752 O67789 3VYW
t:34 mnm5s2U
t:34 mnm5U
methyltransferase Aquifex aeolicus
MnmE tRNA uridine(34) 5-carboxymethylaminomethyl synthesis GTPase ThdF, TrmE 2851487 b3706 COG0486 P25522 2GJ8, 2GJ9, 2GJA
t:34 mnm5s2U
t:34 mnm5U
t:34 cmnm5Um
t:34 cmnm5s2U
MnmE/MnmG GTPase Escherichia coli
MnmE tRNA modification GTPase MnmE ThdF, TrmE 21674894 COG0486 Q8KAS1 3GEE, 3GEI
t:34 cmnm5s2U
t:34 cmnm5U
MnmE/MnmG GTPase Chlorobium tepidum
MnmE tRNA modification GTPase MnmE TrmE 17232169 COG0486 Q8YN91 3GEH
t:34 cmnm5s2U
t:34 cmnm5U
MnmE/MnmG GTPase Nostoc sp.
MnmE tRNA modification GTPase MnmE TrmE 15643037 COG0486 Q9WYA4 1XZP, 1XZQ
t:34 cmnm5s2U
t:34 cmnm5U
MnmE/MnmG GTPase Thermotoga maritima
MnmG tRNA uridine(34) 5-carboxymethylaminomethyl synthesis enzyme GidA, TrmF 62288115 b3741 COG0445 P0A6U3 3CP2, 3CES
t:34 mnm5s2U
t:34 mnm5U
t:34 cmnm5Um
t:34 cmnm5s2U
MnmG/MnmE other Escherichia coli
MnmG tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GidA 21675089 COG0445 Q8KA85 3CP8
t:34 cmnm5s2U
t:34 cmnm5U
MnmG/MnmE other Chlorobium tepidum
MnmG tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GidA 15606146 COG0445 O66962 2ZXH, 2ZXI
t:34 cmnm5s2U
t:34 cmnm5U
MnmG/MnmE other Aquifex aeolicus
MnmH tRNA 2-selenouridine(34) synthase SelU, YbbB 2506609 ybbB, b0503 COG2603 P33667
t:34 cmnm5ges2U
t:34 mnm5se2U
t:34 mnm5ges2U
selenotransferase/geranyltransferase Escherichia coli
Mod5 tRNA dimethylallyltransferase, mitochondrial IPTase, IPPT 2507067 YOR274W COG0324 P07884 3EPH, 3EPK, 3EPJ, 3EPL
t:37 i6A
dimethylallyltransferase Saccharomyces cerevisiae
Mod5 tRNA dimethylallyltransferase, mitochondrial TRIT1, IPT 31581534 COG0324 Q9H3H1
t:37 i6A
dimethylallyltransferase Homo sapiens
Mrm1 rRNA methyltransferase, mitochondrial Pet56 1346886 YOR201C COG0566 P25270
l:2270(2251) Gm
methyltransferase Saccharomyces cerevisiae
Mrm2 Ribosomal RNA methyltransferase MRM2, mitochondrial 1723920 YGL136C COG0293 P53123
l:2791(2552) Um
methyltransferase Saccharomyces cerevisiae
Mss1 tRNA modification GTPase MSS1 Pet53 1709142 YMR023C COG0486 P32559
Mss1/Mto1 GTPase Saccharomyces cerevisiae
MtaB Threonylcarbamoyladenosine tRNA methylthiotransferase MtaB YqeV 1730990 BSU25430 COG0621 P54462
t:37 ms2t6A
methyltiotransferase Bacillus subtilis
MtaB Threonylcarbamoyladenosine tRNA methylthiotransferase tRNA-t(6)A37 methylthiotransferase, Cdkal1 21617853 COG0621 Q91WE6
t:37 ms2t6A
methylthiotransferase Mus musculus
Mto1 Mitochondrial translation optimization protein 1 Ips1 115502421 YGL236C COG0445 P53070
t:34 cmnm5s2U
Mto1/Mss1 other Saccharomyces cerevisiae
Mtu1 Mitochondrial tRNA-specific 2-thiouridylase 1 Mto2, SLM3 6320172 D2761 COG0482 Q12093
t:34 cmnm5s2U
sulfurtransferase Saccharomyces cerevisiae
NAT10 N-acetyltransferase 10 ALP, KIAA1709 221316723 COG1444 Q9H0A0
s:1338(1060) ac4C
s:1843(1510) ac4C
acetyltransferase Homo sapiens
NFS1 NFS1, cysteine desulfurase NifS, IscS None Q9Y697
desulfurase Homo sapiens
NHP2L1 NHP2-like protein 1 15.5kD 51317376 COG1358 P55769 1E7K, 2OZB
C/D RNP Homo sapiens
NRM Nosiheptide Resistance Methyltransferase Nosiheptide Resistance Methyltransferase None
l:1067(1067) Am
methylthiotransferase Streptomyces actuosus
NSUN3 tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial NOL1/NOP2/Sun domain family member 3 None
methyltransferase Homo sapiens
NSUN4 5-methylcytosine rRNA methyltransferase NSUN4, mitochondrial NOL1/NOP2/Sun domain family member 4 370879165 4FP9
s:841(None) m5C
methyltransferase Homo sapiens
NSUN6 tRNA (cytosine-5-)-methyltransferase NSUN6 1189131264 5WWT, 5WWQ, 5WWR, 5WWS,
methyltransferase Homo sapiens
Ncs2 Cytoplasmic tRNA 2-thiolation protein 2 CTU2, TUC2 125863506 N1913 COG0037 P53923
t:34 mcm5s2U
Nsc2/Ncs6 thiolase Saccharomyces cerevisiae
Ncs6 Cytoplasmic tRNA 2-thiolation protein 1 Ctu1, Tuc1 50593215 YGL211W COG0037 P53088
t:34 cmnm5s2U
Nsc2/Ncs6 thiolase Saccharomyces cerevisiae
Nep1 Ribosomal RNA small subunit methyltransferase NEP1 Emg1 6323215 L9470.5 COG1756 Q06287 3BBD, 3BBE, 3BBH
s:1191(966) m1Y
methyltransferase Saccharomyces cerevisiae
Nep1 Ribosomal RNA small subunit methyltransferase Nep1 MJ0557 20532166 COG1756 Q57977 3BBE, 3BBD, 3BBH
s:914(966) m1Y
methyltransferase Methanocaldococcus jannaschii
Nfs1 Cysteine desulfurase, mitochondrial Spl1 45644965 YCL017C COG1104 P25374
cysteine desulfurase Saccharomyces cerevisiae
Nhp2 H/ACA ribonucleoprotein complex subunit 2 15.5kD 59799862 YDL208W COG1358 P32495
H/ACA RNP Saccharomyces cerevisiae
Nop1 rRNA 2′-O-methyltransferase fibrillarin Fibrillarin, Lot3p 6320190 YDL014W COG1889 P15646
s:many Xm
l:many Xm
C/D RNP methyltransferase Saccharomyces cerevisiae
Nop10 H/ACA ribonucleoprotein complex subunit 3 54036193 YHR072W-A COG2260 Q6Q547 1Y2Y, 3UAI, 3U28
H/ACA RNP Saccharomyces cerevisiae
Nop2 Nucleolar protein 2 Yna1, N2428, YNL2428W 730166 YNL061W COG0144 P40991
l:2870(2501) m5C
methyltransferase Saccharomyces cerevisiae
Nop56 Nucleolar protein 56 Sik1 2833223 YLR197W COG1498 Q12460
C/D RNP Saccharomyces cerevisiae
Nop56/58 Archaeal nucleolar protein homolog Nop5, PF0060 18976432 COG1498 Q8U4M1 2NNW, 3NVM
C/D RNP Pyrococcus furiosus
Nop56/58 Pre mRNA splicing protein Nop5, SSO0939 15897820 COG1498 Q97ZH3 3ICX, 3ID5, 3ID6
C/D RNP Sulfolobus solfataricus
Nop56/58 Archaeal nucleolar protein homolog Nop5, AF_2088 11499670 COG1498 O28191 1NT2
C/D RNP Archaeoglobus fulgidus
Nop58 Nucleolar protein 58 Nop5p 2833225 YOR310C COG1498 Q12499
C/D RNP Saccharomyces cerevisiae
NpmA rRNA adenine N-1-methyltransferase aminoglycoside-resistance 16S rRNA methyltransferase 157734594 npmA COG0220 A8C927 3P2E, 3P2I, 3P2K, 3PB3, 3MTE, 4OX9
s:1408(1408) m1A
methyltransferase Escherichia coli
Nsr rRNA (adenosine-2'-O-)-methyltransferase Nosiheptide-resistance methyltransferase 1654413 nsh P72385 3NK6, 3NK7
l:1067(1067) Am
methyltransferase Streptomyces actuosus
OSGEP O-sialoglycoprotein endopeptidase PRSMG1 GCPL1 OSGEP1 KAE1 TCS3 None Q9NPF4
endopeptidase Homo sapiens
PUS10 pseudouridine synthase 10 FLJ32312 None Q3MIT2
pseudouridine synthase Homo sapiens
PUS3 tRNA pseudouridine(38/39) synthase 199559784 FKSG32
pseudouridine synthase Homo sapiens
PUS7 pseudouridine synthase 7 FLJ20485 None Q96PZ0
pseudouridine synthase Homo sapiens
Pcc1 PF2011 18978383 COG2892 Q8TZI1 3ENC, 3ENO
t:37 t6A
EKC/KEOPS methyltransferase Pyrococcus furiosus
Pcc1 Polarized growth chromatin-associated controller 1 YKR095W-A 398365493 COG2892 Q3E833
t:37 t6A
EKC/KEOPS methyltransferase Saccharomyces cerevisiae
Pmt1 Protein O-MannosylTransferase YDL095W None PMT1
methyltransferase Schizosaccharomyces pombe
Pus1 tRNA pseudouridine synthase 1 3122655 YPL212C COG0101 Q12211
t:27 Y
t:28 Y
t:35 Y
t:34 Y
t:36 Y
n:44 Y
pseudouridine synthase Saccharomyces cerevisiae
Pus1 tRNA pseudouridine synthase 1, mitochondrial 70166645 PP8985 COG0101 Q9Y606 4J37,4ITS,4IQM,4NZ7,4NZ6
t:28 Y
t:27 Y
other:236 Y
t:30 Y
pseudouridine synthase Homo sapiens
Pus10 tRNA pseudouridine synthase Pus10 PusX 74536148 COG1258 Q8U1R6
t:54 Y
t:55 Y
pseudouridine synthase Pyrococcus furiosus
Pus2 tRNA pseudouridine synthase 2 347595823 YGL063W COG0101 P53167
t:27 Y
pseudouridine synthase Saccharomyces cerevisiae
Pus3 tRNA pseudouridine synthase 3 Deg1p, Hrm3 399356 YFL001W COG0101 P31115
t:39 Y
t:38 Y
pseudouridine synthase Saccharomyces cerevisiae
Pus4 tRNA pseudouridine synthase 4 1353109 YNL292W COG0130 P48567
t:55 Y
pseudouridine synthase Saccharomyces cerevisiae
Pus5 Pseudouridine synthase 5 74644954 YLR165c COG0564 Q06244
l:2819(2580) Y
pseudouridine synthase Saccharomyces cerevisiae
Pus6 Pseudouridylate synthase 6 1723726 YGR169C COG0564 P53294
t:31 Y
pseudouridine synthase Saccharomyces cerevisiae
Pus7 Multisubstrate pseudouridine synthase 7 6324817 YOR243C COG0585 Q08647
t:13 Y
s:many Y
n:56 Y
t:35 Y
n:35 Y
pseudouridine synthase Saccharomyces cerevisiae
Pus8 Bifunctional protein RIB2 Rib2 2501674 YOL066c COG0564 Q12362
t:32 Y
pseudouridine synthase/deaminase Saccharomyces cerevisiae
Pus9 tRNA pseudouridine synthase 9, mitochondrial 6320168 YDL036c COG0564 Q12069
t:32 Y
pseudouridine synthase Saccharomyces cerevisiae
QTRT2 queuine tRNA-ribosyltransferase accessory subunit 2 FLJ12960 None Q9H974
transglycosylase Homo sapiens
Qri7 t(6)A37 threonylcarbamoyladenosine biosynthesis protein QRI7 OSGEPL, YDL104C 6320099 D2366 COG0533 P43122 3WUH
t:37 t6A
threonylcarbamoyltransferase Saccharomyces cerevisiae
QueA tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase 67471968 b0405 COG0809 P0A7F9
t:34 QtRNA
isomerase Escherichia coli
QueF preQ1 synthase YgcD 2495654 yqcD, b2794 COG2904 Q46920
t:34 QtRNA
oxidoreductase Escherichia coli
QueF NADPH-dependent 7-cyano-7-deazaguanine reductase ykvM, BSU13750 81555909 COG0780 O31678 4F8B, 4FGC
t:34 QtRNA
oxidoreductase Bacillus subtilis
QueG tRNA epoxyqueuosine(34) reductase YjeS 16131988 COG1600 P39288
t:34 QtRNA
oxidoreductase Escherichia coli
RNMTL1 RNA methyltransferase-like protein 1 8922534 HC90 COG0566 Q9HC36
l:1370(2553) Gm
methyltransferase Homo sapiens
RPUSD4 RNA pseudouridylate synthase domain-containing protein 4 None
l:1397(None) Y
pseudouridine synthase Homo sapiens
Rcm1 Ribosomal RNA Cytosine Methyltransferase 1 Ynl022c 398365407 N2815 COG0144 P53972
l:2278(1935) m5C
methyltransferase Saccharomyces cerevisiae
Rit1 tRNA A64-2′-O-ribosylphosphate transferase 1350603 YMR283C, YM8021.09C COG2365 P23796
t:64 Ar(p)
phosphotransferase Saccharomyces cerevisiae
RlmA(I) Ribosomal RNA large subunit methyltransferase A RrmA, YebH 549542 b1822 COG2226 P36999 1P91
l:745(745) m1G
methyltransferase Escherichia coli
RlmA(II) 23S rRNA (guanine(748)-N(1))-methyltransferase TlrB 4210927 COG2226 Q9S1M6
l:748(748) m1G
methyltransferase Streptomyces fradiae
RlmB Ribosomal RNA large subunit methyltransferase B YjfH, JW4138 52783780 b4180 COG0566 P63177 1GZ0
l:2251(2251) Gm
methyltransferase Escherichia coli
RlmC Ribosomal RNA large subunit methyltransferase C YbgF, RumB 2501407 ybgF, b0859 COG2265 P75817
l:747(747) m5U
methyltransferase Escherichia coli
RlmC 23S rRNA (uracil(747)-C(5))-methyltransferase PYRAB11450 50401700 PAB0760 COG2265 Q9UZK1
l:887(747) m5U
methyltransferase Pyrococcus abyssi
RlmCD 23S rRNA (uracil-C(5))-methyltransferase RlmCD YefA 50401309 BSU06730 COG2265 O31503
l:749(747) m5U
l:1968(1939) m5U
methyltransferase Bacillus subtilis
RlmCD 23S rRNA (Uracil-C(5))-methyltransferase RlmCD None SpnNT_01953
methyltransferase Streptococcus pneumoniae
RlmD Ribosomal RNA large subunit methyltransferase D RumA, YgcA 388478792 ygcA, b2776 COG2265 P55138 2BH2, 1UWV
l:1939(1939) m5U
methyltransferase Escherichia coli
RlmE Ribosomal RNA large subunit methyltransferase E RrmJ, Ftsj, MrsF, JW3146 83287970 b3179, c3936, z4541, Ecs4058 COG0293 P0C0R7 1EIZ,1EJO
l:2552(2552) Um
methyltransferase Escherichia coli
RlmF Ribosomal RNA large subunit methyltransferase F YbiN, JW5107 3915947 b0807 COG3129 P75782
l:1618(1618) m6A
methyltransferase Escherichia coli
RlmFO 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmFO Mcap0476 123535705 COG1206 Q2SS13
l:1947(1939) m5U
methyltransferase Mycoplasma capricolum
RlmG Ribosomal RNA large subunit methyltransferase G YgjO 90111535 b3084, JW5513 COG2813 P42596
l:1835(1835) m2G
methyltransferase Escherichia coli
RlmH Ribosomal RNA large subunit methyltransferase H YbeA 67476028 b0636 COG1576 P0A8I8 1NS5
l:1915(1915) m3Y
methyltransferase Escherichia coli
RlmI Ribosomal RNA large subunit methyltransferase I yccW, JW5898 13432272 b0967 COG1092 P75876 3C0K
l:1962(1962) m5C
methyltransferase Escherichia coli
RlmJ Ribosomal RNA large subunit methyltransferase J yhiR 586675 b3499, JW3466 COG2961 P37634 4BLW,4BLV,4BLU
l:2030(2030) m6A
methyltransferase Escherichia coli
RlmKL Ribosomal RNA large subunit methyltransferase KL YcbY 2501582 b0948, JW0931 COG0116 P75864 3V8V, 3V97
l:2069(2069) m7G
l:2445(2445) m2G
methyltransferase Escherichia coli
RlmM Ribosomal RNA large subunit methyltransferase M YgdE 83287984 b1976 COG2933 P0ADR6
l:2498(2498) Cm
methyltransferase Escherichia coli
RlmN tRNA (adenosine(37)-C2)-methyltransferase / Ribosomal RNA large subunit methyltransferase N TrmG, YfgB 549552 b2517 COG0820 P36979 3RF9, 3RFA
t:37 m2A
l:2503(2503) m2A
methyltransferase Escherichia coli
RlmO Ribosomal RNA large subunit methyltransferase O TTHA1493 55981462 COG1092 Q5SI81 4DMG
l:1964(1942) m5C
methyltransferase Thermus thermophilus
RluA tRNA pseudouridine(32) synthase / Ribosomal large subunit pseudouridine synthase A YabO 76363883 yabO, b0058 COG0564 P0AA37 2I82
t:32 Y
l:746(746) Y
pseudouridine synthase Escherichia coli
RluB Ribosomal large subunit pseudouridine synthase B YciL 1175678 yciL, b1269 COG1187 P37765
l:2605(2605) Y
pseudouridine synthase Escherichia coli
RluB Ribosomal large subunit pseudouridine synthase B 251757325 ypul COG1187 P35159
l:2633(2604) Y
pseudouridine synthase Bacillus subtilis
RluC Ribosomal large subunit pseudouridine synthase C YceC 76363884 yceC, b1086 COG0564 P0AA39 1V9K, 1XPI
l:2504(2504) Y
l:2580(2580) Y
l:955(955) Y
pseudouridine synthase Escherichia coli
RluD Ribosomal large subunit pseudouridine synthase D YfiI, SfhB 2507541 yfiI, b2594 COG0564 P33643 1PRZ, 1QYU, 1V9F, 2IST
l:1911(1911) Y
l:1915(1915) Y
l:1917(1917) Y
pseudouridine synthase Escherichia coli
RluE Ribosomal large subunit pseudouridine synthase E YmfC 3916025 ymfC, b1135 COG1187 P75966 2OML, 2OLW
l:2457(2457) Y
pseudouridine synthase Escherichia coli
RluF Ribosomal large subunit pseudouridine synthase F YjbC 418534 yjbC, b4022 COG1187 P32684 2GML, 3DH3
l:2604(2604) Y
pseudouridine synthase Escherichia coli
RmtB 16S rRNA methyltransferase RmtB 410610030 Q763K9 3FRI, 3FRH, 3B89
s:1405(1405) m7G
methyltransferase Escherichia coli
Rra1 Ribosomal RNA cytidine Acetyltransferase 1 KRE33 6324197 N1216, N1858 COG1444 P53914
t:12 ac4C
s:1773(1510) ac4C
s:1280(1060) ac4C
acetyltransferase Saccharomyces cerevisiae
Rrp8 Ribosomal RNA-processing protein 8 YDR083W 398365487 D4461 COG0500 P38961
l:645(571) m1A
methyltransferase Saccharomyces cerevisiae
RsmA Ribosomal RNA small subunit methyltransferase A KsgA, JW0050 125699 b0051 COG0030 P06992 1QYR, 3TPZ, 4ADV
s:1518(1518) m6,6A
s:1519(1519) m6,6A
methyltransferase Escherichia coli
RsmA Dimethyladenosine transferase Dim1 1169344 YPL266W COG0030 P41819
s:1779(1518) m6,6A
s:1780(1519) m6,6A
methyltransferase Saccharomyces cerevisiae
RsmA Ribosomal RNA small subunit methyltransferase A At5g66360 42573814 AT5G66360 COG0030 Q9FK02
s:1914(1518) m6,6A
s:1915(1519) m6,6A
methyltransferase Arabidopsis thaliana
RsmA Dimethyladenosine transferase 1, mitochondrial DIMT1, h-mtTFB1 74751555 CGI-75 COG0030 Q8WVM0
methyltransferase Homo sapiens
RsmA Ribosomal RNA small subunit methyltransferase A KsgA, Dim1, MJ1029 15669218 COG0030 Q58435 3FYD, 3FYC, 3GRR, 3GRU, 3GRV, 3GRY
methyltransferase Methanocaldococcus jannaschii
RsmA Ribosomal RNA small subunit methyltransferase A KsgA, TTHA0083 55980052 COG0030 Q5SM60 3FUT, 3FUU, 3FUW, 3FUV, 3FUX
s:1491(1518) m6,6A
s:1492(1519) m6,6A
methyltransferase Thermus thermophilus
RsmB Ribosomal RNA small subunit methyltransferase B Fmu/Fmv, RrmB, Sun, YhdB 1169715 b3289 COG0144 P36929 1SQF, 1SQG
s:967(967) m5C
methyltransferase Escherichia coli
RsmC Ribosomal RNA small subunit methyltransferase C YjjT 732118 yjjT, b4371 COG2813 P39406 2PJD
s:1207(1207) m2G
methyltransferase Escherichia coli
RsmD Ribosomal RNA small subunit methyltransferase D YhhF 83288061 b3465, JW3430 COG0742 P0ADX9 2FPO
s:966(966) m2G
methyltransferase Escherichia coli
RsmD Ribosomal RNA small subunit methyltransferase D Rv2966c 15610103 COG0742 P95128 3P9N
methyltransferase Mycobacterium tuberculosis
RsmE Ribosomal RNA small subunit methyltransferase E YggJ 84027953 b2946 COG1385 P0AGL7
s:1498(1498) m3U
methyltransferase Escherichia coli
RsmF Ribosomal RNA small subunit methyltransferase F YebU, JW5301 3915994 b1835 COG0144 P76273 2FRX
s:1407(1407) m5C
methyltransferase Escherichia coli
RsmF Ribosomal RNA small subunit methyltransferase F TTHA1387 55981356 COG0144 Q5SII2 3M6U, 3M6V, 3M6W, 3M6X
s:1378(1400) m5C
s:1382(1404) m5C
s:1385(1407) m5C
methyltransferase Thermus thermophilus
RsmG Ribosomal RNA small subunit methyltransferase G GidB, JW3718 62288117 b3740 COG0357 P0A6U5 1XDZ, 1JSX
s:527(527) m7G
methyltransferase Escherichia coli
RsmG Ribosomal RNA small subunit methyltransferase G gidB 121190 COG0357 P25813 1XDZ
s:533(527) m7G
methyltransferase Bacillus subtilis
RsmG Ribosomal RNA small subunit methyltransferase G GidB, TTHA1971 62298017 COG0357 Q9LCY2 3G8B, 3G88, 3G89, 3G8A
s:510(527) m7G
methyltransferase Thermus thermophilus
RsmH Ribosomal RNA small subunit methyltransferase H mraW 42560200 COG0275 P60390 3TKA
s:1402(1402) m4Cm
methyltransferase Escherichia coli
RsmI Ribosomal RNA small subunit methyltransferase I yraL 1789535 COG0313 P67087
s:1403(1403) m4Cm
methyltransferase Escherichia coli
RsmJ Ribosomal RNA small subunit methyltransferase J YhiQ 388479744 COG0742 P68567 2PGX
s:1516(1516) m2G
methyltransferase Escherichia coli
RsuA Ribosomal small subunit pseudouridine synthase A YejD 76364197 yejD, b2183, c2720, z3442, ECs3075, SF2270, S2399 COG1187 P0AA43 1KSV, 1KSL, 1KSK
s:516(516) Y
pseudouridine synthase Escherichia coli
SCS9 SUPPRESSOR OF CSB3 9 None
t:32 Xm
t:34 Xm
methyltransferase Arabidopsis thaliana
Sap185 SIT4-associating protein SAP185 6322363 J0840 COG2253 P40856
thiolase Saccharomyces cerevisiae
Sap190 SIT4-associating protein SAP190 330443662 COG2253 P36123
thiolase Saccharomyces cerevisiae
SelD Selenide,water dikinase FdhB 134423 b1764 COG0709 P16456
selenophosphate synthase Escherichia coli
Sgm rRNA adenine N-7-methyltransferase Sisomicin-gentamicin resistance methylase 75383291 sgm COG2263 Q7M0R2 3LCU, 3LCV
s:1405(1405) m7G
methyltransferase Micromonospora zionensis
Sit4 Serine/threonine-protein phosphatase PP1-1 PPH1 6320156 D2693 COG0639 P20604
protein phosphatase Saccharomyces cerevisiae
Snu13 13 kDa ribonucleoprotein-associated protein YEL026W 731411 YEL026W COG1358 P39990 2ALE
C/D RNP Saccharomyces cerevisiae
Spb1 AdoMet-dependent rRNA methyltransferase SPB1 YCL54W, YCL431 6226708 YCL054W COG0293 P25582
l:2922(2551) Gm
methyltransferase Saccharomyces cerevisiae
Sua5 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 417826 G1660 COG0009 P32579
t:37 t6A
EKC/KEOPS threonylcarbamoyladenosine synthetase Saccharomyces cerevisiae
TFB1M Dimethyladenosine transferase 1, mitochondrial h-mtTFB, CGI75 315013580
s:936(None) m6,6A
s:937(None) m6,6A
methyltransferase Homo sapiens
TGT Queuine tRNA-ribosyltransferase catalytic subunit 1 QTRT1, TGUT 221218971
Homo sapiens
THG1L tRNA-histidine guanylyltransferase 1 like ICF45 FLJ11601 FLJ20546 IHG-1 hTHG1 None Q9NWX6
guanylyltransferase Homo sapiens
THUMPD1 THUMP domain containing 1 FLJ20274, Tan1 None Q9NXG2
Homo sapiens
TP53RK TP53 regulating kinase dJ101A2.2 prpk Nori-2p BUD32 None Q96S44
Homo sapiens
TPRKB TP53RK binding protein CGI-121 CGI121 None Q9Y3C4
Homo sapiens
TRM112 tRNA methyltransferase 112 homolog TRMT112 7705477 AD-001, HSPC152, HSPC170 COG2835 Q9UI30
methyltransferase Homo sapiens
TRM5 tRNA (guanine(37)-N1)-methyltransferase KIAA1393, TRMT5 145275187 COG2520 Q32P41
t:37 m1G
t:37 o2yW
methyltransferase Homo sapiens
TRMO tRNA-methyltransferase O 118600979 HSPC219 COG1720 Q9BU70
t: m6t6A
methyltransferase Homo sapiens
TRMT10A tRNA methyltransferase 10 homolog A RG9MTD2 22748659 Q8TBZ6 4FMW
t:9 m1G
methyltransferase Homo sapiens
TRMT10B tRNA methyltransferase 10 homolog B RG9MTD3 117606330 Q6PF06
t:9 m1G
methyltransferase Homo sapiens
TRMT10C tRNA methyltransferase 10 C, mitochondrial MRPP1, RG9MTD1 117647226 Q7L0Y3
t:9 m1G
t:9 m1A
mtRNase P methyltransferase Homo sapiens
TYW1 tRNA wybutosine-synthesizing protein 1 2501612 YPL207W COG0731 Q08960
t:37 yW
methyltransferase Saccharomyces cerevisiae
TYW2 tRNA wybutosine-synthesizing protein 2 Trm12, YMA5 2497109 YML005W COG2520 Q04235
t:37 yW
Alpha-amino-alpha-carboxypropyltransferase Saccharomyces cerevisiae
TYW2 tRNA wybutosine-synthesizing protein 2 TRMT12 74726289 COG2520 Q53H54
t:37 o2yW
Alpha-amino-alpha-carboxypropyltransferase Homo sapiens
TYW3 tRNA wybutosine-synthesizing protein 3 YGL050W 1322543 COG1590 P53177
t:37 yW
methyltransferase Saccharomyces cerevisiae
TYW4 Leucine carboxyl methyltransferase 2 PPM2, LCMT2 1420038 YOL141W Q08282 2ZW9, 2ZWA, 2ZZK
t:37 yW
methyltransferase, carboxymethyltransferase Saccharomyces cerevisiae
TYW5 tRNA yW-synthesizing enzyme 5 C2orf60 89242134 KOG2130 A2RUC4 3AL5, 3AL6
t:37 o2yW
hydroxylase Homo sapiens
Tad1 tRNA-specific adenosine deaminase 1 ADAT1, YGL243W 1723979 HRA400 COG0590 P53065
t:37 m1I
deaminase Saccharomyces cerevisiae
Tad1 tRNA-specific adenosine deaminase 1 hADAT1 302058269 ADAT1 Q9BUB4
t:37 m1I
deaminase Homo sapiens
Tad2 tRNA-specific adenosine deaminase subunit TAD2 ADAT2 1352970 YJL035C COG0590 P47058
t:34 I
Tad2/3 deaminase Saccharomyces cerevisiae
Tad2 tRNA-specific adenosine deaminase 2 ADAT2 72392897 Tb927.8.4180 COG0590 Q57W17
t:34 I
Tad2/3 deaminase Trypanosoma brucei
Tad3 tRNA-specific adenosine deaminase subunit TAD3 ADAT3 23822264 YLR316C COG0590 Q9URQ3
t:34 I
Tad2/3 deaminase Saccharomyces cerevisiae
Tad3 tRNA-specific adenosine deaminase 3 ADAT3 74026040 Tb11.01.6930 COG0590 Q381Q7
t:34 I
Tad2/3 deaminase Trypanosoma brucei
TadA tRNA-specific adenosine deaminase YfhC 90108581 yfhC, b2559 COG0590 P68398 1Z3A
t:34 I
deaminase Escherichia coli
TadA tRNA-specific adenosine deaminase, chloroplastic AtTadA 15221490 F14K14.18, F24J5.5 COG0590 Q9S7I0
t:34 I
deaminase Arabidopsis thaliana
Tan1 tRNA acetyltransferase TAN1 1723972 YGL232W COG1818 P53072
t:12 ac4C
Rra1/Tan1 Saccharomyces cerevisiae
Taw1 tRNA wyosine derivatives biosynthesis protein Taw1 MjTYW1 2501613 MJ0257 COG0731 Q57705
oxidoreductase Methanocaldococcus jannaschii
Taw1 tRNA wyosine derivatives biosynthesis protein Taw1 Tyw1 74571635 PH1705 COG0731 O59412 2YX0
oxidoreductase Pyrococcus horikoshii
Taw1 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase Tyw1 14520684 PAB2039 COG0731 Q9V1F9
t:37 mimG
oxidoreductase Pyrococcus abyssi
Taw2 tRNA wyosine derivatives biosynthesis protein Taw2 3025176 MJ1557 COG2520 Q58952 3A27
Alpha-amino-alpha-carboxypropyltransferase Methanocaldococcus jannaschii
Taw2 tRNA wyosine derivatives biosynthesis protein Taw2 74570968 PH0793 COG2520 O58523 3A25, 3A26
Alpha-amino-alpha-carboxypropyltransferase Pyrococcus horikoshii
Taw22 tRNA (guanine(37)-N1)-methyltransferase Trm5a/Taw22 Trm5a 14520331 PAB2272 COG2520 Q9V2G1
t:37 mimG
methyltransferase Pyrococcus abyssi
TcdA tRNA threonylcarbamoyladenosine dehydratase A YgdL, CsdL 16130719 csdL COG1179 Q46927 4RDI,4RDH,4D7A,4D79
t:37 ct6A
dehydratase Escherichia coli
Tgs1 Trimethylguanosine synthase 1 P2573 74583797 YPL157W COG0116 Q12052
snoRNA:0 m2,2,7Gpp(pN)
n:0 m2,2,7Gpp(pN)
methyltransferase Saccharomyces cerevisiae
Tgs1 trimethylguanosinesynthase 1 PRIP-interacting protein with methyltransferase motif (PIMT) 317373500 TGS1 COG2263 Q96RS0 3EGI, 3GDH
n:0 m2,2,7Gpp(pN)
snoRNA:0 m2,2,7Gpp(pN)
methyltransferase Homo sapiens
Tgs2 RNA cap guanine-N2 methyltransferase 159108485 GL50803_5613 COG2265 A8BW33
snoRNA:0 m2,2,7Gpp(pN)
n:0 m2,2,7Gpp(pN)
methyltransferase Giardia lamblia
Tgt tRNA guanosine(34) transglycosylase JW0396 67473024 b0406 COG0343 P0A847
t:34 QtRNA
transglycosylase Escherichia coli
Tgt Queuine tRNA-ribosyltransferase ZMO0363 283856241 COG0343 P28720 1Q2R, 1Q2S, 1WKF
t:34 preQ1tRNA
transglycosylase Zymomonas mobilis
TgtA 7-cyano-7-deazaguanine tRNA-ribosyltransferase Tgt, HVO_2001 13516848 Q9C4M3
t:15 G+
transglycosylase Haloferax volcanii
TgtA 7-cyano-7-deazaguanine tRNA-ribosyltransferase PH1116 14590946 COG0343 O58843 1J2B, 1IT8
t:15 preQ1tRNA
transglycosylase Pyrococcus horikoshii
Thg1 tRNA(His) guanylyltransferase 45270428 YGR024c COG4021 P53215
t:0 G
guanylyltransferase Saccharomyces cerevisiae
ThiI tRNA 4-thiouridine(8) synthase NuvA 2501549 b0423 COG0301 P77718
t:8 s4U
sulfurtransferase Escherichia coli
TiaS tRNA(Ile2) 2-agmatinylcytidine synthase TiaS AF_2259 74511356 COG1571 O28025 3AMU, 3AU7, 3AMT
agmatidine synthase Archaeoglobus fulgidus
TiaS tRNA(Ile2) 2-agmatinylcytidine synthase TiaS PF1855 18978227 COG1571 Q8TZX0 3U02
t:34 C+
agmatidine synthase Pyrococcus furiosus
TilS tRNA lysidine(34) synthetase MesJ, YaeN 1708989 b0188 COG0037 P52097 1WY5, 3A2K
t:34 k2C
lysidine synthase Escherichia coli
TilS tRNA(Ile)2-lysidine synthase GK0060 56418595 COG0037 Q5L3T3 3A2K, 3HJ7
t:34 k2C
lysidine synthase Geobacillus kaustophilus
TmcA tRNA cytidine(34) acetyltransferase YpfI, JW2459 2495648 b2474 COG1444 P76562 2ZPA
t:34 ac4C
acetyltransferase Escherichia coli
Trm-G10 tRNA (guanine(10)-N2)-dimethyltransferase (Pab)Trm-G10, PYRAB16240 327488511 PAB1283 COG1041 Q9UY84
t:10 m2,2G
methyltransferase Pyrococcus abyssi
Trm1 tRNA (guanine(26)-N(2))-dimethyltransferase, mitochondrial 136242 YDR120C COG1867 P15565
t:26 m2,2G
methyltransferase Saccharomyces cerevisiae
Trm1 tRNA (guanine(26)-N(2)/guanine(27)-N(2))-dimethyltransferase aq_841 15606194 COG1867 O67010 3AXS, 3AXT
t:26 m2,2G
t:27 m2,2G
methyltransferase Aquifex aeolicus
Trm1 tRNA (guanine(26)-N(2))-dimethyltransferase PH1829 14591578 COG1867 O59493 2DUL, 2EJT, 2EJU, 2YTZ
t:26 m2,2G
methyltransferase Pyrococcus horikoshii
Trm1 tRNA (guanine(26)-N(2))-dimethyltransferase hTRM1p 209862871 TRMT1 COG1867 Q9NXH9
t:26 m2,2G
methyltransferase Homo sapiens
Trm10 tRNA (guanine-N(1)-)-methyltransferase O0926 74645051 YOL093W COG2419 Q12400 4JWJ
t:9 m1G
methyltransferase Saccharomyces cerevisiae
Trm10 tRNA (adenine(9)-N1)-methyltransferase None 5A7T, 5A7Y, 5A7Z
methyltransferase Sulfolobus acidocaldarius
Trm11 tRNA guanosine-2′-O-methyltransferase TRM11 74655048 YOL124C COG1041 Q12463
t:10 m2G
methyltransferase Saccharomyces cerevisiae
Trm112 Multifunctional methyltransferase subunit TRM112 1730682 YNR046W COG2835 P53738 5CM2
Saccharomyces cerevisiae
Trm13 tRNA-2′-O-methyltransferase TRM13 6324447 YOL125w COG2230 Q12383
t:4 Cm
t:4 Am
methyltransferase Saccharomyces cerevisiae
Trm140 140 kDa actin-binding protein Abp140 398365899 COG2226 Q08641
t:32 m3C
methyltransferase Saccharomyces cerevisiae
Trm2 tRNA (uracil-5-)-methyltransferase Nud1, Rnc1 110825750 YKR056W COG2265 P33753
t:54 m5U
methyltransferase Saccharomyces cerevisiae
Trm3 tRNA (guanosine(18)-2′-O)-methyltransferase 74627230 YDL112W COG0566 Q07527
t:18 Gm
methyltransferase Saccharomyces cerevisiae
Trm4 Multisite-specific tRNA:(cytosine-C(5))-methyltransferase Ncl1p 586408 YBL024W COG0144 P38205
t:40 m5C
t:48 m5C
t:34 m5C
methyltransferase Saccharomyces cerevisiae
Trm4 tRNA (cytosine(34)-C(5))-methyltransferase hMisu, SAKI 39995082 NSUN2 COG0144 Q08J23
pre-tRNA:48 m5C
pre-tRNA:34 m5C
m:many m5C
other:many m5C
t:48 m5C
t:49 m5C
t:50 m5C
methyltransferase Homo sapiens
Trm4 tRNA (cytosine(49)-C(5))-methyltransferase PYRAB06230 14520840 PAB1947 COG0144 Q9V106
t:49 m5C
methyltransferase Pyrococcus abyssi
Trm44 tRNA (uridine-O(2)-)-methyltransferase 6325227 YPL030w COG2227 Q02648
t:44 Um
methyltransferase Saccharomyces cerevisiae
Trm5 tRNA (guanine-N(1)-)-methyltransferase 731672 YHR070W COG2520 P38793
t:37 m1I
t:37 yW
t:37 m1G
methyltransferase Saccharomyces cerevisiae
Trm5b tRNA (guanine(37)-N1)-methyltransferase Trm5b MJ0883 15669073 COG2520 Q58293 2ZZM, 2ZZN, 3AY0, 2YX1
t:37 m1G
methyltransferase Methanocaldococcus jannaschii
Trm5b tRNA (guanine(37)-N1)-methyltransferase Trm5b 14520947 PAB0505 COG2520 Q9V0Q0
t:37 yW-72
methyltransferase Pyrococcus abyssi
Trm6 tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 GCD10, TIF33 603585 YNL062C COG2519 P41814
Trm6/Trm61 Saccharomyces cerevisiae
Trm61 tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61 GCD14 6322336 YJL125C COG2519 P46959
t:58 m1A
Trm6/Trm61 methyltransferase Saccharomyces cerevisiae
Trm7 tRNA (cytidine(32)/guanosine(34)-2′-O)-methyltransferase Ybr1, FtsJ 586500 YBR061C COG0293 P38238
t:34 Gm
t:34 ncm5Um
t:32 Cm
methyltransferase Saccharomyces cerevisiae
Trm8 tRNA (guanine-N(7)-)-methyltransferase 32171782 YDL201W COG0220 Q12009 2VDU, 2VDV
t:46 m7G
Trm8/Trm82 methyltransferase Saccharomyces cerevisiae
Trm82 tRNA (guanine-N(7)-)-methyltransferase subunit TRM82 32363272 YDR165W COG2319 Q03774 2VDU
Trm8/Trm82 Saccharomyces cerevisiae
Trm9 tRNA (uracil-5-)-methyltransferase TRM9 YM9571.04 1730616 YML014W COG2226 P49957 5CM2
t:34 mcm5s2U
t:34 mcm5U
Trm9/Trm112 methyltransferase Saccharomyces cerevisiae
TrmA tRNA (uridine(54)-C5)-methyltransferase RumT 136247 b3965 COG2265 P23003 3BT7
t:54 m5U
methyltransferase Escherichia coli
TrmB tRNA (guanine(46)-N7)-methyltransferase YggH 67473592 b2960 COG0220 P0A8I5 3DXX, 3DXY, 3DXZ
t:46 m7G
methyltransferase Escherichia coli
TrmB tRNA (guanine-N(7)-)-methyltransferase ytmQ 14194920 COG0220 O34522 2FCA
t:46 m7G
methyltransferase Bacillus subtilis
TrmD tRNA (guanosine(37)-N1)-methyltransferase JW2588 67473571 b2607 COG0336 P0A873 1P9P
t:37 m1G
methyltransferase Escherichia coli
TrmFO Methylenetetrahydrofolate--tRNA-(uracil-54-)-methyltransferase TrmFO Gid, YlyC 3183519 BSU16130 COG1206 P39815
t:54 m5U
methyltransferase Bacillus subtilis
TrmFO Methylenetetrahydrofolate-tRNA-(uracil-54-)-methyltransferase TrmFO 55981411 COG1206 Q5SID2 3G5Q, 3G5R, 3G5S
t:54 m5s2U
methyltransferase Thermus thermophilus
TrmH tRNA (guanosine(18)-2′-O)-methyltransferase SpoU 84029292 z5077, ECs4526, SF3691, S4078, b3651 COG0566 P0AGJ2
t:18 Gm
methyltransferase Escherichia coli
TrmH tRNA (guanosine(18)-2′-O)-methyltransferase SpoU 55980096 TTHA0127 COG0566 Q9FAC4 1V2X
t:18 Gm
methyltransferase Thermus thermophilus
TrmI tRNA (adenine(57)-N(1)/adenine(58)-N(1))-methyltransferase TrmI pimT-like 5457862 PAB0283 COG2519 Q9V1J7 3LGA,3LHD,3MB5
t:58 m1A
t:57 m1I
methyltransferase Pyrococcus abyssi
TrmI tRNA (adenine(58)-N(1))-methyltransferase TrmI TT_C0244 46198552 COG2519 Q8GBB2 2PWY
t:58 m1A
methyltransferase Thermus thermophilus
TrmI tRNA (adenine(58)-N(1))-methyltransferase TrmI Rv2118c, MT2178 81669088 COG2519 O33253 1I9G
t:58 m1A
methyltransferase Mycobacterium tuberculosis
TrmJ tRNA (cytidine(32)/uridine(32)-2′-O)-methyltransferase YfhQ, JW2516 83287928 b2532 COG0565 P0AE01 4CND, 4CNE
t:32 Um
t:32 Cm
methyltransferase Escherichia coli
TrmJ tRNA (cytidine(32)-2′-O)-methyltransferase Saci_0621 70606436 COG0565 Q4JB16 4CNF, 4CNG
t:32 Cm
methyltransferase Sulfolobus acidocaldarius
TrmK tRNA (adenine(22)-N(1))-methyltransferase 332278123 YqfN P54471
t:22 m1A
methyltransferase Bacillus subtilis
TrmL tRNA (cytidine(34)-2′-O)-methyltransferase YibK 16131477 b3606, JW3581 COG0219 P0AGJ7 4JAK, 4JAL
t:34 Cm
t:34 cmnm5Um
methyltransferase Escherichia coli
TrmM tRNA (adenosine(37)-N6)-methyltransferase YfiC, TrmN6 13638617 COG4123 P31825
t:37 m6A
methyltransferase Escherichia coli
TrmN tRNA (guanine(6)-N2)-methyltransferase Trm14, MJ0438 15668614 COG0116 Q57880
t:6 m2G
methyltransferase Methanocaldococcus jannaschii
TrmN tRNA (guanine(6)-N2)-methyltransferase Trm14 46199459 TTC1157 COG0116 Q72IH5 3TMA
t:6 m2G
methyltransferase Thermus thermophilus
TrmO tRNA-methyltransferase O TsaA, YaeB 16128188 COG1720 P28634
t:37 m6t6A
methyltransferase Escherichia coli
TrmR tRNA mo5U methyltransferase yrrM, putative acyl-CoA O-methyltransferase None O32036 5ZW3
t:34 mo5U
methyltransferase Bacillus subtilis
TrmU Mitochondrial tRNA-specific 2-thiouridylase 1 MTU1, TRMT1 31542641 COG0482 O75648
t:34 tm5s2U
sulfurtransferase Homo sapiens
TrmU54 tRNA (uracil(54)-C(5))-methyltransferase PYRAB10780 14521283 PAB0719 COG2265 Q9UZR7 2VS1, 2JJQ
t:54 m5U
methyltransferase Pyrococcus abyssi
TrmY tRNA(pseudouridine54-N1)-methyltransferase HVO_1989 292656118 COG1901 D4GTL8
t:54 m1Y
methyltransferase Haloferax volcanii
TrmY tRNA(pseudouridine54-N1)-methyltransferase MJ1640 15669836 COG1901 Q59034 3AI9, 3AIA
t:54 m1Y
methyltransferase Methanocaldococcus jannaschii
Trmt6 tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 KIAA1153, TRM6 19923475 CGI-09 COG2519 Q9UJA5 5CCB,5CD1,5CCX
Trm6/Trm61 Homo sapiens
Trmt61A tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A C14orf172, TRM61 123173772 COG2519 Q96FX7 5CCB,5CD1,5CCX
t:58 m1A
Trm6/Trm61 methyltransferase Homo sapiens
Trmt61B tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial 222831587 COG2519 Q9BVS5 2B25
t:58 m1A
methyltransferase Homo sapiens
TruA tRNA pseudouridine(38,39,40) synthase HisT, AsuC, HisT, LeuK 123176 b2318 COG0101 P07649 1DJ0, 2NQP, 2NR0, 2NRE
t:39 Y
t:40 Y
t:38 Y
pseudouridine synthase Escherichia coli
TruB tRNA pseudouridine(55) synthase YhbA 42560511 yhbA, b3166 COG0130 P60340 1K8W, 1R3F, 1R3E, 1SGV, 1ZL3
t:55 Y
pseudouridine synthase Escherichia coli
TruC tRNA pseudouridine(65) synthase YqcB 108936020 yqcB, b2791 COG0564 P0AA41
t:65 Y
pseudouridine synthase Escherichia coli
TruD tRNA pseudouridine(13) synthase YgbO 2501601 ygbO, b2745 COG0585 Q57261 1SB7, 1SI7, 1SZW
t:13 Y
pseudouridine synthase Escherichia coli
TsaB tRNA N6-threonylcarbamoyladenosine(37) synthesis protein YeaZ 16129761 COG1214 P76256 1OKJ
t:37 t6A
TsaBDE endopeptidase Escherichia coli
TsaC tRNA N6-threonylcarbamoyladenosine(37) synthesis protein RimN, yrdC 2851671 COG0009 P45748 1HRU
t:37 t6A
threonylcarbamoyladenosine synthetase Escherichia coli
TsaD tRNA N6-threonylcarbamoyladenosine(37) synthesis protein YgjD 16130960 COG0533 P05852
t:37 t6A
TsaBDE threonylcarbamoyltransferase Escherichia coli
TsaE UPF0079 ATP-binding protein ydiB YdiB 16077658 COG0802 O05515
ATPase Bacillus subtilis
TsaE tRNA N6-threonylcarbamoyladenosine(37) synthesis protein YjeE 16131990 COG0802 P0AF67
t:37 t6A
TsaBDE ATPase Escherichia coli
Tsr rRNA (adenosine-2'-O-)-methyltransferase Thiostrepton Resistance 23S rRNA methyltransferase 136456 tsr COG0566 P18644 3GYQ
l:1067(1067) Am
methyltransferase Streptomyces cyaneus
TtcA tRNA 2-thiocytidine(32) synthetase YdaO 2495598 b1344 COG0037 P76055
t:32 s2C
thiolase Escherichia coli
TtuA tRNA-two-thiouridine synthesizing protein A TT_C0106 46198414 COG0037 Q72LF3
t:54 m5s2U
sulfurtransferase Thermus thermophilus
Tum1 Thiosulfate sulfurtransferase TUM1 51012915 COG2897 Q08686
thiosulfate sulfurtransferase Saccharomyces cerevisiae
TusA tRNA 2-thiouridine(34) synthase sirA, yhhP 16131342 COG0425 P0A890 3LVK, 3LVJ, 1DCJ
sulfurtransferase Escherichia coli
TusB tRNA 2-thiouridine(34) synthase yheL 16131222 COG2168 P45530 2D1P
TusBCD Escherichia coli
TusC tRNA 2-thiouridine(34) synthase yheM 16131223 COG2923 P45531 2D1P
TusBCD Escherichia coli
TusD tRNA 2-thiouridine(34) synthase yheN 16131224 COG1553 P45532 2D1P
TusBCD sulfurtransferase Escherichia coli
TusE tRNA 2-thiouridine synthesizing protein E yccK 90111197 COG2920 P0AB18
sulfurtransferase Escherichia coli
URM1 ubiquitin related modifier 1 MGC2668 None Q9BTM9
Homo sapiens
Uba4 Adenylyltransferase and sulfurtransferase UBA4 NCS3 6321903 COG0476 P38820
adenylyltransferase, sulfurtransferase Saccharomyces cerevisiae
Urm1 Ubiquitin-related modifier 1 45270480 COG5131 P40554
thiosulfate sulfurtransferase Saccharomyces cerevisiae
WBSCR22 18S rRNA (guanine-N(7))-methyltransferase MERM1, BUD23 21552765
s:1639(1338) m7G
WBSCR22-TRMT112 methyltransferase Homo sapiens
WDR4 tRNA (guanine-N(7)-)-methyltransferase subunit WDR4 16445428 COG2319 P57081
TRMB/WDR4 Homo sapiens
aTrm56 tRNA (cytidine(56)-2'-O)-methyltransferase PH0461 14590372 COG1303 O58214 2YY8
t:56 Um
methyltransferase Pyrococcus horikoshii
aTrm56 tRNA (cytidine(56)-2'-O)-methyltransferase 14521775 PAB1040 COG1303 Q9UYD1
t:56 Cm
methyltransferase Pyrococcus abyssi
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