| Full name: |
tRNA methyltransferase 10 homolog B |
| Synonym: |
RG9MTD3 |
| GI: |
117606330 |
| Orf: |
|
| COG: |
|
| UniProt: |
Q6PF06 |
| Structures: |
|
|
|
| Complex: |
|
| Enzyme type: |
methyltransferase |
| Position of modification - modification: |
t:9 - m1G
|
Comments:
Ortholog of yeast Trm10, cytoplasmic.
Protein sequence:
MDWKLEGSTQKVESPVLQGQEGILEETGEDGLPEGFQLLQIDAEGECQEGEILATGSTAWCSKNVQRKQR
HWEKIVAAKKSKRKQEKERRKANRAENPGICPQHSKRFLRALTKDKLLEAKHSGPRLCIDLSMTHYMSKK
ELSRLAGQIRRLYGSNKKADRPFWICLTGFTTDSPLYEECVRMNDGFSSYLLDITEEDCFSLFPLETLVY
LTPDSEHALEDVDLNKVYILGGLVDESIQKKVTFQKAREYSVKTARLPIQEYMVRNQNGKNYHSEILAIN
QVFDILSTYLETHNWPEALKKGVSSGKGYILRNSVE
Enzymatic activities:
| Reaction
| Substrate
| Type
| Position
|
|
G:m1G
|
tRNA (t) |
|
9 |
Publications:
| Title |
Authors |
Journal |
Details |
PubMed Id |
DOI |
| A subcomplex of human mitochondrial RNase P is a bifunctional methyltransferase--extensive moonlighting in mitochondrial tRNA biogenesis. |
Vilardo E, Nachbagauer C, Buzet A, Taschner A, Holzmann J, Rossmanith W... |
Nucleic Acids Res |
[details]
|
23042678
|
-
|