Modomics - A Database of RNA Modifications

Full name:	tRNA methyltransferase 10 homolog B
Synonym:	RG9MTD3
GI:	117606330
Orf:
COG:
UniProt:	Q6PF06
Structures:	\| \|
Complex:
Enzyme type:	methyltransferase
Position of modification - modification:	t:9 - m1G

Comments:

Ortholog of yeast Trm10, cytoplasmic.

Protein sequence:

MDWKLEGSTQKVESPVLQGQEGILEETGEDGLPEGFQLLQIDAEGECQEGEILATGSTAWCSKNVQRKQRHWEKIVAAKKSKRKQEKERRKANRAENPGI
CPQHSKRFLRALTKDKLLEAKHSGPRLCIDLSMTHYMSKKELSRLAGQIRRLYGSNKKADRPFWICLTGFTTDSPLYEECVRMNDGFSSYLLDITEEDCF
SLFPLETLVYLTPDSEHALEDVDLNKVYILGGLVDESIQKKVTFQKAREYSVKTARLPIQEYMVRNQNGKNYHSEILAINQVFDILSTYLETHNWPEALK
KGVSSGKGYILRNSVE

Enzymatic activities:

Reaction	Substrate	Type	Position
G:m1G	tRNA (t)		9

Publications:

Title	Authors	Journal	Details	PubMed Id	DOI
A subcomplex of human mitochondrial RNase P is a bifunctional methyltransferase--extensive moonlighting in mitochondrial tRNA biogenesis.	Vilardo E, Nachbagauer C, Buzet A, Taschner A, Holzmann J, Rossmanith W...	Nucleic Acids Res	[details]	23042678	-