Modomics - A Database of RNA Modifications

Full name:
Synonym:	YLR063W
GI:	6323092
Orf:	L2174
COG:
UniProt:	Q12291
Structures:	\| \|
Complex:
Enzyme type:	methyltransferase
Position of modification - modification:	l:2843(2474) - m3U

Comments:

Localized predominantly in the cytoplasm.

Protein sequence:

MLLMRRFAFLTSSVYFKYIPIYSQYHYSSQFPINMNPKKVAQLPVHNKSTLPPQEIIDLFKITFLEELYPKDQDNEKSPLTEQIQAVKSDLYNRDYNAAF
NNDSKRIAYCCRWSPSRATSYASVFAHFPELLKIIRCEIDDKDSNVLCIGGGAGGELVALASIFTLSRDFSSKFASALKIDNEVNKKPRNLNIQLVDIAD
WSTVVEKLTATIKSKWLYGDSEAESFNVNFTHKDCLQMTEPQDIKIYQGLDLITLLFTTNELFTQKKVESIKFLQRLNENCAPGCHLLILESAGSYSHIT
INNKKFPIQFLIDTILVGNRKDKGTTGPWSLVSENDSIWYRMDPKLDYSIPLENMRFFYRLYVKN

Enzymatic activities:

Reaction	Substrate	Type	Position
U:m3U	rRNA (r)	LSU-L/25S/eukaryotic cytosol	2843

Publications:

Title	Authors	Journal	Details	PubMed Id	DOI
Identification of novel methyltransferases, Bmt5 and Bmt6, responsible for the m3U methylations of 25S rRNA in Saccharomyces cerevisiae.	Sharma S, Yang J, Duttmann S, Watzinger P, Kotter P, Entian KD...	Nucleic Acids Res	[details]	24335083	-